产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
转铁蛋白受体(CD71)重组兔单克隆抗体[JF0956](ET1702-06)
目录 :
ET1702-06
规格 :
单克隆
价格 :
JF0956
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
JF0956
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
ET1702-06
产品名称 :
转铁蛋白受体(CD71)重组兔单克隆抗体[JF0956](ET1702-06)
类别 :
Recombinant Rabbit monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
JF0956
宿主 :
兔
应用 :
免疫印迹, 免疫组化-P, 免疫沉淀, FC
应用w/稀释 :
WB: 1:1, 000-1:2, 000;FC:1:50-1:100;免疫组化-P:1:50-1:200
反应物种 :
人类, 小鼠, 大鼠
免疫原 :
Synthetic peptide within human CD71 aa 10-50.
抗体亚型 :
IgG
靶蛋白 :
转铁蛋白受体(CD71)
靶标.UniProt数据库 :
P02786
靶标.同义词 :
CD 71 antibody; CD71 antibody; CD71 antigen antibody; IMD46 antibody; OTTHUMP00000208523 antibody; OTTHUMP00000208524 antibody; OTTHUMP00000208525 antibody; p90 antibody; sTfR antibody; T9 antibody; TFR 1 antibody; TfR antibody; TfR1 antibody; TFR1_HUMAN antibody; TFRC antibody; TR antibody; Transferrin receptor (p90 CD71) antibody; Transferrin receptor protein 1, serum form antibody; Trfr antibody
Target function/background :
CD71, also known as the transferrin receptor (TFR), is a type II membrane glycoprotein that exists as a disulfide-linked homodimer of two identical subunits. CD71 binds to two molecules of transferrin and a serum iron-transport protein, and directs the cellular uptake of iron via receptor-mediated endocytosis. CD71 is expressed, typically at high levels, on all proliferating cells, reticulocytes and erythroid precursors. It is not expressed on resting leukocytes, but is upregulated upon activation of lymphocytes, monocytes and macrophages. CD71 is also found on most dividing cells and on brain endothelium. A second transferrin receptor, TFR2, also mediates the uptake of transferrin-bound iron. TFR2 is a two-subunit homodimer and is highly expressed in liver as well as in hepatocytes and erythroid precursors. Mutations in the TFR2 gene result in hereditary hemochromatosis type III (HFE3), an iron overloading disorder predominant in Caucasians.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
85 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
355
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!
We hope to see you at your next discovery!