产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
MHC class I Recombinant Rabbit Monoclonal Antibody [JF10-38] (ET1702-47)
目录 :
ET1702-47
规格 :
单克隆
价格 :
JF10-38
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
JF10-38
反应物种 :
人类
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
ET1702-47
产品名称 :
MHC class I Recombinant Rabbit Monoclonal Antibody [JF10-38] (ET1702-47)
类别 :
Recombinant Rabbit monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
JF10-38
宿主 :
应用 :
免疫印迹, 免疫细胞化学, IF, 免疫组化-P, FC
应用w/稀释 :
WB: 1:1, 000-1:5, 000;免疫细胞化学/IF:1:100-1:500;免疫组化-P:1:50-1:200;FC:1:50-1:100
反应物种 :
人类
免疫原 :
Synthetic peptide within human HLA aa 270-310.
抗体亚型 :
IgG
靶蛋白 :
MHC class I
靶标.UniProt数据库 :
P04439
靶标.同义词 :
A 28 antibody; A 9 antibody; Antigen presenting molecule antibody; Aw 24 antibody; Aw 68 antibody; CLASS I HISTOCOMPATIBILITY ANTIGEN antibody; H2 K1 antibody; H2K antibody; HLA A antibody; HLA class I histocompatibility antigen A 1 alpha chain antibody; HLA class I histocompatibility antigen A 11 alpha chain antibody; HLA class I histocompatibility antigen A 2 alpha chain antibody; HLA class I histocompatibility antigen A 24 alpha chain antibody; HLA class I histocompatibility antigen A 3 alpha chain antibody; HLA class I histocompatibility antigen A 30 alpha chain antibody; HLA class I histocompatibility antigen A 32 alpha chain antibody; HLA class I histocompatibility antigen A 68 alpha chain antibody; HLAA antibody; Leukocyte antigen class I A antibody; Major histocompatibility complex class I A antibody; MHC class I antigen A 1 antibody; MHC class I antigen A*11 antibody; MHC class I antigen A*2 antibody; MHC class I antigen A*24 antibody; MHC class I antigen A*3 antibody; MHC class I antigen A*30 antibody; MHC class I antigen A*32 antibody; MHC class I antigen A*68 antibody; MHC class I antigen HLA A heavy chain antibody; MHC class I heavy chain H2 K antibody
Target function/background :
Major histocompatibility complex (MHC) molecules, also designated human leukocyte antigen (HLA) molecules, are cell-surface receptors that bind foreign peptides and present them to T lymphocytes. MHC class I molecules consist of two polypeptide chains, an a or heavy chain, and β-2-Microglobulin, a non-covalently associated protein. Cytotoxic T lymphocytes bind antigenic peptides presented by MHC class I molecules. Antigens that bind to MHC class I molecules are typically 8-10 residues in length and are stabilized in a peptide binding groove. MHC class II molecules are encoded by polymorphic MHC genes and consist of a non-covalent complex of an a and b chain. Helper T lymphocytes bind antigenic peptides presented by MHC class II molecules. MHC class II molecules bind 13-18 amino acid antigenic peptides. Accumulating in endosomal/lysosomal compartments and on the surface of B cells, HLA-DM and -DO molecules regulate binding of exogenous peptides to class II molecules (HLA-DR) by sustaining a conformation that favors peptide exchange. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
41 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
355
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!