产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
过氧化物酶体增殖物激活受体γ重组兔单克隆抗体[JF101-4](ET1702-57)
目录 :
ET1702-57
规格 :
单克隆
价格 :
JF101-4
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
JF101-4
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹
更多信息或购买 :
HUABIO 产品网页
产品信息
Catalog# :
ET1702-57
产品名称 :
过氧化物酶体增殖物激活受体γ重组兔单克隆抗体[JF101-4](ET1702-57)
类别 :
Recombinant Rabbit monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
JF101-4
宿主 :
兔
应用 :
免疫印迹
应用w/稀释 :
WB: 1:1, 000-1:2, 000
反应物种 :
人类, 小鼠, 大鼠
免疫原 :
Synthetic peptide within human PPAR gamma aa 110-150.
抗体亚型 :
IgG
靶蛋白 :
过氧化物酶体增殖物激活受体γ
靶标.UniProt数据库 :
P37231
靶标.同义词 :
CIMT1 antibody; GLM1 antibody; NR1C3 antibody; Nuclear receptor subfamily 1 group C member 3 antibody; OTTHUMP00000185032 antibody; OTTHUMP00000185036 antibody; Peroxisome proliferator activated nuclear receptor gamma variant 1 antibody; Peroxisome proliferator activated receptor gamma 1 antibody; Peroxisome Proliferator Activated Receptor gamma antibody; Peroxisome proliferator-activated receptor gamma antibody; PPAR gamma antibody; PPAR-gamma antibody; PPARG antibody; PPARG_HUMAN antibody; PPARG1 antibody; PPARG2 antibody; PPARgamma antibody
Target function/background :
Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptor subfamily of transcription factors. PPARs form heterodimers with retinoid X receptors (RXRs). These heterodimers regulate transcription of genes involved in insulin action, adipocyte differentiation, lipid metabolism and inflammation. PPARγ is implicated in numerous diseases including obesity, diabetes, atherosclerosis and cancer. PPARγ activators include prostanoids, fatty acids, thiazolidinediones and N-(2-benzoylphenyl) tyrosine analogues. A key component in adipocyte differentiation and fat-specific gene expression, PPARγ may modulate macrophage functions such as proinflammatory activities, and stimulate oxidized low-density lipoprotein (x-LDL) uptake. A Pro12Ala polymorphism of the PPARγ2 gene has been reported to reduce transactivation activity in vitro. This substitution may affect the immune response to ox-LDL and be associated with type 2 diabetes. In addition, the Pro12Ala variant of the PPARγ2 gene maybe correlated with abdominal obesity in type 2 diabetes.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
58 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
355
launch date :
2020&prior
更多信息或购买 :
HUABIO 产品网页
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!