产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
GATA4重组兔单克隆抗体[JA11-41](ET1704-32)
目录 :
ET1704-32
规格 :
单克隆
价格 :
JA11-41
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
JA11-41
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪
更多信息或购买 :
HUABIO 产品网页
产品信息
Catalog# :
ET1704-32
产品名称 :
GATA4重组兔单克隆抗体[JA11-41](ET1704-32)
类别 :
Recombinant Rabbit monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
JA11-41
宿主 :
兔
应用 :
免疫印迹, 免疫细胞化学, IF, FC
应用w/稀释 :
WB: 1:500-1:1, 000;免疫细胞化学/IF:1:50-1:200;FC:1:50-1:100
反应物种 :
人类, 小鼠, 大鼠
免疫原 :
重组蛋白
抗体亚型 :
IgG
靶蛋白 :
GATA4
靶标.UniProt数据库 :
P43694
靶标.同义词 :
ASD2 antibody; GATA 4 antibody; GATA binding protein 4 antibody; GATA-binding factor 4 antibody; gata4 antibody; GATA4_HUMAN antibody; MGC126629 antibody; Transcription factor GATA 4 antibody; Transcription factor GATA-4 antibody; Transcription factor GATA4 antibody; VSD1 antibody
Target function/background :
Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as in erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. Both GATA-4 and GATA-6 are found in heart, pancreas and ovary; lung and liver tissues exhibit GATA-6, but not GATA-4 expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart. Although expression patterns of the various GATA transcription factors may overlap, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
54 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
355
launch date :
2020&prior
更多信息或购买 :
HUABIO 产品网页
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!