产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
CD16重组兔单克隆抗体[JE49-79](ET7109-97)
目录 :
ET7109-97
规格 :
单克隆
价格 :
JE49-79
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
JE49-79
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
ET7109-97
产品名称 :
CD16重组兔单克隆抗体[JE49-79](ET7109-97)
类别 :
Recombinant Rabbit monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
JE49-79
宿主 :
应用 :
免疫印迹, 免疫组化-P
应用w/稀释 :
WB:1:500;免疫组化-P:1:50-1:200
反应物种 :
人类, 小鼠, 大鼠
免疫原 :
Recombinant protein within human CD16 aa 154-254.
抗体亚型 :
IgG
靶蛋白 :
CD16
靶标.UniProt数据库 :
P08637
靶标.同义词 :
CD 16 antibody; CD 16a antibody; CD16 antibody; CD16a antibody; CD16a antigen antibody; CD16B antibody; CD16b antigen antibody; Fc fragment of IgG antibody; Fc fragment of IgG low affinity IIIa receptor (CD16) antibody; Fc fragment of IgG low affinity IIIa receptor antibody; Fc fragment of IgG receptor IIIa antibody; Fc fragment of IgG, low affinity III, receptor (CD16) antibody; Fc fragment of IgG, low affinity III, receptor for (CD16) antibody; Fc fragment of IgG, low affinity IIIa, receptor (CD16) antibody; Fc fragment of IgG, low affinity IIIa, receptor (CD16a) antibody; Fc fragment of IgG, low affinity IIIa, receptor for antibody; Fc fragment of IgG, low affinity IIIb, receptor (CD16b) antibody; Fc fragment of IgG, low affinity IIIb, receptor for (CD16) antibody; Fc gamma R3 antibody; Fc gamma receptor III 2 (CD 16) antibody; Fc gamma receptor III A antibody; Fc gamma receptor IIIA antibody; Fc gamma receptor IIIb (CD 16) antibody; Fc gamma RIII alpha antibody; Fc gamma RIII antibody; Fc gamma RIII beta antibody; Fc gamma RIIIa antibody; Fc gamma RIIIb antibody; Fc of IgG antibody; Fc-gamma receptor III2 (CD 16) antibody; Fc-gamma receptor III2 (CD16) antibody; Fc-gamma receptor IIIb (CD16) antibody; Fc-gamma RIII antibody; Fc-gamma RIII-alpha antibody; Fc-gamma RIIIa antibody; FCG 3 antibody; FCG3 antibody; FCG3A_HUMAN antibody; FCgammaRIIIA antibody; FCGR 3 antibody; FCGR 3A antibody; FCGR3 antibody; FCGR3A antibody; FCGR3A protein antibody; FCGRIII antibody; FCGRIII-2 antibody; FcR 10 antibody; FcR-10 antibody; FcR10 antibody; FcRIII antibody; FcRIIIa antibody; IGFR 3 antibody; IGFR3 antibody; IgG Fc receptor III 1 antibody; IgG Fc receptor III 2 antibody; IgG Fc receptor III-2 antibody; IMD20 antibody; immunoglobulin G Fc receptor III antibody; immunoglobulin G Fc receptor III-2 antibody; Low affinity IIIa receptor antibody; Low affinity immunoglobulin gamma Fc region receptor III A antibody; Low affinity immunoglobulin gamma Fc region receptor III-A antibody; Low affinity immunoglobulin gamma Fc region receptor IIIB antibody; neutrophil-specific antigen NA antibody
Target function/background :
CD16, also known as FcγRIII, is a cluster of differentiation molecule found on the surface of natural killer cells, neutrophils, monocytes, and macrophages. CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), which participate in signal transduction. The most well-researched membrane receptor implicated in triggering lysis by NK cells, CD16 is a molecule of the immunoglobulin superfamily (IgSF) involved in antibody-dependent cellular cytotoxicity (ADCC). It can be used to isolate populations of specific immune cells through fluorescent-activated cell sorting (FACS) or magnetic-activated cell sorting, using antibodies directed towards CD16. CD16 is the type III Fcγ receptor. In humans, it exists in two different forms: FcγRIIIa (CD16a) and FcγRIIIb (CD16b), which have 96% sequence similarity in the extracellular immunoglobulin binding regions. While FcγRIIIa is expressed on mast cells, macrophages, and natural killer cells as a transmembrane receptor, FcγRIIIb is only expressed on neutrophils. In addition, FcγRIIIb is the only Fc receptor anchored to the cell membrane by a glycosyl-phosphatidylinositol (GPI) linker, and also plays a significant role in triggering calcium mobilization and neutrophil degranulation. FcγRIIIa and FcγRIIIb together are able to activate degranulation, phagocytosis, and oxidative burst, which allows neutrophils to clear opsonized pathogens.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
分子量 :
Predicted band size: 29 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
355
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!