产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
CD5重组兔单克隆抗体[JE25-41](ET7110-56)
目录 :
ET7110-56
规格 :
单克隆
价格 :
JE25-41
克隆性 :
单克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
JE25-41
反应物种 :
人类
应用 :
免疫印迹, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
ET7110-56
产品名称 :
CD5重组兔单克隆抗体[JE25-41](ET7110-56)
类别 :
Recombinant Rabbit monoclonal primary
共轭 :
未共轭
克隆性 :
单克隆
克隆编号 :
JE25-41
宿主 :
兔
应用 :
免疫印迹, 免疫组化-P
应用w/稀释 :
WB:1:500-1:2, 000;免疫组化-P:1:50
反应物种 :
人类
免疫原 :
Synthetic peptide within N terminal Human CD5.
抗体亚型 :
IgG
靶蛋白 :
CD5
靶标.UniProt数据库 :
P06127
靶标.同义词 :
CD 5 antibody; CD5 antibody; CD5 antigen (p56 62) antibody; CD5 antigen antibody; CD5 molecule antibody; CD5_HUMAN antibody; LEU1 antibody; LyA antibody; Lymphocyte antigen T1/Leu-1 antibody; OTTHUMP00000236973 antibody; T-cell surface glycoprotein CD5 antibody; T1 antibody
Target function/background :
CD5 is a cluster of differentiation expressed on the surface of T cells (various species) and in a subset of murine B cells known as B-1a. The expression of this receptor in human B cells has been a controversial topic and up to date there is no consensus regarding the role of this receptor as a marker of human B cells. B-1 cells have limited diversity of their B-cell receptor due to their lack of the enzyme terminal deoxynucleotidyl transferase (TdT) and are potentially self-reactive. CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by very strong stimuli (such as bacterial proteins) and not by normal tissue proteins. CD5 was used as a T-cell marker until monoclonal antibodies against CD3 were developed. In humans, the gene is located on the long arm of chromosome 11. There is no confirmed ligand for CD5 but there is evidence that CD72, a C-type lectin, may be a ligand or that CD5 may be homophilic, binding CD5 on the surface of other cells. CD5 includes a scavenger receptor cysteine-rich protein domain. T cells express higher levels of CD5 than B cells. CD5 is upregulated on T cells upon strong activation. In the thymus, there is a correlation with CD5 expression and strength of the interaction of the T cell towards self-peptides.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
分子量 :
55 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
355
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!
We hope to see you at your next discovery!