产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
Active+Pro Caspase-9 Rabbit Polyclonal Antibody (R1308-12)
目录 :
R1308-12
规格 :
多克隆
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
R1308-12
产品名称 :
Active+Pro Caspase-9 Rabbit Polyclonal Antibody (R1308-12)
类别 :
Rabbit polyclonal primary
共轭 :
未共轭
克隆性 :
多克隆
宿主 :
兔
应用 :
免疫印迹, 免疫组化-P
应用w/稀释 :
WB: 1:1, 000- 1:2, 000;免疫组化-P:1:200
反应物种 :
人类
免疫原 :
Synthetic peptide within human Caspase-9 aa 299-313/416.
抗体亚型 :
IgG
靶蛋白 :
Active+Pro Caspase-9
靶标.UniProt数据库 :
P55211
靶标.同义词 :
APAF-3 antibody; APAF3 antibody; Apoptosis related cysteine peptidase antibody; Apoptotic protease Mch-6 antibody; Apoptotic protease-activating factor 3 antibody; CASP-9 antibody; CASP9 antibody; CASP9_HUMAN antibody; Caspase 9 apoptosis related cysteine peptidase antibody; Caspase 9 Dominant Negative antibody; Caspase 9c antibody; Caspase-9 antibody; Caspase-9 subunit p10 antibody; ICE LAP6 antibody; ICE like apoptotic protease 6 antibody; ICE-LAP6 antibody; ICE-like apoptotic protease 6 antibody; MCH6 antibody; PPP1R56 antibody; protein phosphatase 1, regulatory subunit 56 antibody; RNCASP9 antibody
Target function/background :
Caspase-9 (ICE-LAP6, Mch6) is an important member of the cysteine aspartic acid protease (caspase) family. It is known to be involved in the activation cascade of caspases responsible for apoptosis execution. Upon apoptotic stimulation, cytochrome c released from mitochondria associates with the 47 kDa procaspase-9/Apaf 1. Apaf-1 mediated activation of caspase-9 involves instrinsic proteolytic processing resulting in cleavage at Asp315 and producing a p35 subunit. Another cleavage occurs at Asp330 producing a p37 subunit that can serve to amplify the apoptotic response. Cleaved caspase-9 further processes other caspase members, including caspase-3 and caspase-7, to initiate a caspase cascade, which leads to apoptosis.
产品形式 :
液体
纯化 :
免疫原亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
46/30/37 kDa (Predicted band size)
供应商 :
HUABIO
Volume :
100ul
价格 :
295
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!
We hope to see you at your next discovery!