产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
γ-微管兔多克隆抗体(R1411-2)
目录 :
R1411-2
规格 :
多克隆
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
R1411-2
产品名称 :
γ-微管兔多克隆抗体(R1411-2)
类别 :
Rabbit polyclonal primary
共轭 :
未共轭
克隆性 :
多克隆
宿主 :
应用 :
免疫印迹, 免疫细胞化学, 免疫组化-P
应用w/稀释 :
WB: 1: 1, 000
反应物种 :
人类, 小鼠, 大鼠
免疫原 :
Synthetic peptide within C-terminalhuman Gamma tubulin.
抗体亚型 :
IgG
靶蛋白 :
γ-微管
靶标.UniProt数据库 :
P23258
靶标.同义词 :
Gamma 1 tubulin antibody; Gamma 2 tubulin antibody; Gamma Tubulin 1 antibody; Gamma Tubulin 2 antibody; Gamma tubulin complex component 1 antibody; Gamma-2-tubulin antibody; GCP 1 antibody; GCP1 antibody; MGC131994 antibody; TBG2_HUMAN antibody; TUBG antibody; TUBG1 antibody; TUBG2 antibody; TUBGCP1 antibody; Tubulin gamma 1 chain antibody; Tubulin gamma 2 chain antibody; Tubulin gamma complex-associated protein 1 antibody; Tubulin gamma-2 chain antibody; tubulin, gamma 1 antibody; tubulin, gamma 2 antibody; tubulin, gamma polypeptide antibody; Xgam antibody
Target function/background :
The nucleosome, made up of DNA wound around eight core histone proteins (two each of H2A, H2B, H3, and H4), is the primary building block of chromatin. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Methylation at Lys-5 (H3K4me), Lys-37 (H3K36me) and Lys-80 (H3K79me) are linked to gene activation. Methylation at Lys-5 (H3K4me) facilitates subsequent acetylation of H3 and H4. Methylation at Lys-80 (H3K79me) is associated with DNA double-strand break (DSB) responses and is a specific target for TP53BP1. Methylation at Lys-10 (H3K9me) and Lys-28 (H3K27me) are linked to gene repression. Methylation at Lys-10 (H3K9me) is a specific target for HP1 proteins (CBX1, CBX3 and CBX5) and prevents subsequent phosphorylation at Ser-11 (H3S10ph) and acetylation of H3 and H4. Methylation at Lys-5 (H3K4me) and Lys-80 (H3K79me) require preliminary monoubiquitination of H2B at 'Lys-120'. Methylation at Lys-10 (H3K9me) and Lys-28 (H3K27me) are enriched in inactive X chromosome chromatin.
产品形式 :
液体
纯化 :
肽亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
17 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
295
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!