产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
细胞色素C兔多克隆抗体(R1510-41)
目录 :
R1510-41
规格 :
多克隆
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
蚕属, 人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 1
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 蚕属
Yu H, Wang X, Xu J, Ma Y, Zhang S, Yu D, et al. iTRAQ-based quantitative proteomics analysis of molecular mechanisms associated with Bombyx mori (Lepidoptera) larval midgut response to BmNPV in susceptible and near-isogenic strains. J Proteomics. 2017;165:35-50 pubmed 出版商
产品信息
Catalog# :
R1510-41
产品名称 :
细胞色素C兔多克隆抗体(R1510-41)
类别 :
Rabbit polyclonal primary
共轭 :
未共轭
克隆性 :
多克隆
宿主 :
应用 :
免疫印迹, 免疫细胞化学, 免疫组化-P, FC
应用w/稀释 :
WB: 1:1, 000-1:5, 000;ICC:1:50-1:200;免疫组化-P:1:50-1:200;FC:1:50-1:100
反应物种 :
人类, 小鼠, 大鼠
免疫原 :
Synthetic peptide within N-terminal human Cytochrome C.
抗体亚型 :
IgG
靶蛋白 :
细胞色素c
靶标.UniProt数据库 :
P99999
靶标.同义词 :
CYC antibody; CYC_HUMAN antibody; CYCS antibody; Cytochrome c antibody; Cytochrome c somatic antibody; HCS antibody; THC4 antibody
Target function/background :
Cytochrome c is a well characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial intermembrane space. More recent studies have identifed cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is translocated from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.
产品形式 :
液体
纯化 :
肽亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
12kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
295
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!