产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
Hsc70兔多克隆抗体(R1511-6)
目录 :
R1511-6
规格 :
多克隆
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
R1511-6
产品名称 :
Hsc70兔多克隆抗体(R1511-6)
类别 :
Rabbit polyclonal primary
共轭 :
未共轭
克隆性 :
多克隆
宿主 :
兔
应用 :
免疫印迹, 免疫细胞化学, 免疫组化-P
应用w/稀释 :
WB: 1:500-1:1, 000;ICC:1:50-1:200;免疫组化-P:1:50-1:200
反应物种 :
人类, 小鼠, 大鼠
免疫原 :
Synthetic peptide within N-terminal human HSP73.
抗体亚型 :
IgG
靶蛋白 :
Hsc70
靶标.UniProt数据库 :
P11142
靶标.同义词 :
2410008N15Rik antibody; Constitutive heat shock protein 70 antibody; Epididymis luminal protein 33 antibody; Epididymis secretory sperm binding protein Li 72p antibody; Heat shock 70 kDa protein 8 antibody; Heat shock 70kD protein 10 antibody; Heat shock 70kD protein 8 antibody; Heat shock 70kDa protein 8 antibody; Heat shock cognate 71 kDa protein antibody; Heat shock cognate protein 54 antibody; Heat shock cognate protein 71 kDa antibody; Heat shock protein 8 antibody; Heat shock protein A8 antibody; Heat shock protein family A (Hsp70) member 8 antibody; Heat-shock70-KD protein 10, formerly antibody; HEL 33 antibody; HEL S 72p antibody; HSC54 antibody; HSC71 antibody; Hsc73 antibody; HSP71 antibody; HSP73 antibody; HSP7C_HUMAN antibody; HSPA10 antibody; HSPA8 antibody; LAP1 antibody; Lipopolysaccharide associated protein 1 antibody; LPS associated protein 1 antibody; LPS associated protein antibody; MGC102007 antibody; MGC106514 antibody; MGC114311 antibody; MGC118485 antibody; MGC131511 antibody; MGC29929 antibody; N-myristoyltransferase inhibitor protein 71 antibody; NIP71 antibody
Target function/background :
The HSP 70 family is composed of four highly conserved proteins: HSP 70, HSC 70, GRP 75 and GRP 78. These proteins serve a variety of roles: they act as molecular chaperones facilitating the assembly of multi-protein complexes, participate in the translocation of polypeptides across cell membranes and to the nucleus, and aid in the proper folding of nascent polypeptide chains. All members of the family, except HSP 70, are constitutively expressed in primate cells. HSP 70 expression is strongly induced in response to heat stress. HSP 70 and HSC 70 play key roles in the cytosolic endoplasmic reticulum and mitochondrial import machinery and are found in both the cytosol and nucleus of mammalian cells. Both HSP 70 and HSC 70 are involved in the chaperoning of nascent polypeptide chains and in protecting cells against the accumulation of improperly folded proteins. GRP 78 is localized in the endoplasmic reticulum, where it receives imported secretory proteins and is involved in the folding and translocation of nascent peptide chains. GRP 75 expression is restricted to the mitochondrial matrix and aids in the translocation and folding of nascent polypeptide chains of both nuclear and mitochondrial origin. GRP 75 and GRP 78 are unresponsive to heat stress and are induced by glucose deprivation. It has been postulated that members of the HSP 70 family act as force-generating motors, relying on the hydrolysis of ATP for their activity.
产品形式 :
液体
纯化 :
肽亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
71 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
295
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!
We hope to see you at your next discovery!