产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
PKM2兔多克隆抗体(R1603-5)
目录 :
R1603-5
规格 :
多克隆
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
HUABIO 产品网页
产品信息
Catalog# :
R1603-5
产品名称 :
PKM2兔多克隆抗体(R1603-5)
类别 :
Rabbit polyclonal primary
共轭 :
未共轭
克隆性 :
多克隆
宿主 :
兔
应用 :
免疫印迹, 免疫细胞化学, 免疫组化-P, FC
应用w/稀释 :
WB: 1:500-1:1, 000;ICC:1:50-1:200;免疫组化-P:1:50-1:200;FC:1:50-1:100
反应物种 :
人类, 小鼠, 大鼠
免疫原 :
Recombinant protein corresponding to C terminal of Human PKM2 .
抗体亚型 :
IgG
靶蛋白 :
PKM2
靶标.UniProt数据库 :
P14618
靶标.同义词 :
CTHBP antibody; Cytosolic thyroid hormone binding protein antibody; Cytosolic thyroid hormone-binding protein antibody; KPYM_HUMAN antibody; MGC3932 antibody; OIP 3 antibody; OIP-3 antibody; OIP3 antibody; OPA interacting protein 3 antibody; Opa-interacting protein 3 antibody; p58 antibody; PK muscle type antibody; PK, muscle type antibody; PK2 antibody; PK3 antibody; PKM antibody; PKM2 antibody; pykm antibody; Pyruvate kinase 2/3 antibody; Pyruvate kinase 3 antibody; Pyruvate kinase isozymes M1/M2 antibody; Pyruvate kinase muscle antibody; Pyruvate kinase muscle isozyme antibody; pyruvate kinase PKM antibody; Pyruvate kinase, muscle 2 antibody; TCB antibody; THBP1 antibody; Thyroid hormone binding protein 1 antibody; Thyroid hormone binding protein cytosolic antibody; Thyroid hormone-binding protein 1 antibody; Tumor M2 PK antibody; Tumor M2-PK antibody
Target function/background :
Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival . Promotes in a STAT1-dependent manner, the expression of the immune checkpoint protein CD274 in ARNTL/BMAL1-deficient macrophages (By similarity).
产品形式 :
液体
纯化 :
蛋白亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
分子量 :
58 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
295
launch date :
2020&prior
更多信息或购买 :
HUABIO 产品网页
公司信息
HUABIO
Boston, Massachusetts
support@huabio.com
https://www.huabio.com
1-857-353-6600
公司总部: 美国
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!