产品简要
公司名称 :
HUABIO
产品类型 :
抗体
产品名称 :
GM130 (cis-Golgi Marker) Rabbit Polyclonal Antibody (R1608-7)
目录 :
R1608-7
规格 :
多克隆
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
Catalog# :
R1608-7
产品名称 :
GM130 (cis-Golgi Marker) Rabbit Polyclonal Antibody (R1608-7)
类别 :
Rabbit polyclonal primary
共轭 :
未共轭
克隆性 :
多克隆
宿主 :
兔
应用 :
免疫印迹, 免疫细胞化学, 免疫组化-P, FC
应用w/稀释 :
WB: 1:500-1:2, 000;ICC:1:50-1:200;免疫组化-P:1:50-1:200;FC:1:50-1:200
反应物种 :
人类, 小鼠, 大鼠
免疫原 :
Recombinant protein within human GM130 aa 64-231.
抗体亚型 :
IgG
靶蛋白 :
GM130 (cis-Golgi Marker)
靶标.UniProt数据库 :
Q08379
靶标.同义词 :
30 kDa cis Golgi matrix protein antibody; 130 kDa cis-Golgi matrix protein antibody; Cis golgi matrix protein GM130 antibody; GM130 antibody; Gm130 autoantigen antibody; GOGA2_HUMAN antibody; GOLGA 2 antibody; Golga2 antibody; Golgi autoantigen antibody; Golgi autoantigen golgin subfamily a 2 antibody; Golgi matrix protein GM130 antibody; Golgin 95 antibody; golgin A2 antibody; Golgin subfamily a 2 antibody; Golgin subfamily A member 2 antibody; Golgin-95 antibody; MGC20672 antibody; SY11 protein antibody
Target function/background :
Peripheral membrane component of the cis-Golgi stack that acts as a membrane skeleton that maintains the structure of the Golgi apparatus, and as a vesicle thether that facilitates vesicle fusion to the Golgi membrane. Together with p115/USO1 and STX5, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. Plays a central role in mitotic Golgi disassembly. Also plays a key role in spindle pole assembly and centrosome organization. Promotes the mitotic spindle pole assembly by activating the spindle assembly factor TPX2 to nucleate microtubules around the Golgi and capture them to couple mitotic membranes to the spindle. TPX2 then activates AURKA kinase and stimulates local microtubule nucleation. Upon filament assembly, nascent microtubules are further captured by GOLGA2, thus linking Golgi membranes to the spindle. Regulates the meiotic spindle pole assembly, probably via the same mechanism. Also regulates the centrosome organization. Also required for the Golgi ribbon formation and glycosylation of membrane and secretory proteins.
产品形式 :
液体
纯化 :
蛋白质A亲和纯化
浓度 :
1微克/微升
储存缓冲液 :
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
储存空调 :
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
分子量 :
130 kDa
供应商 :
HUABIO
Volume :
100ul
价格 :
295
launch date :
2020&prior
更多信息或购买 :
公司信息
HUABIO
Founded in 2007, HUABIO is dedicated to developing high-quality antibodies that advance innovation. We are passionate about the accuracy, efficiency, and consistency of our products. That is why we have invested in new production platforms, like recombinant rabbit monoclonals, alpaca nanobodies, and adopted aggressive QA standards to deliver cutting-edge antibodies with uncompromised quality.
We hope to see you at your next discovery!
We hope to see you at your next discovery!