产品简要
公司名称 :
Hytest
产品类型 :
抗体
产品名称 :
抗粘蛋白1糖蛋白抗体
目录 :
4M40-M4H2
规格 :
1毫克
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
M4H2
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫沉淀, 酶免疫法
更多信息或购买 :
Hytest 产品网页
文章摘录数: 2
出版应用/物种/样本/稀释参考文献
  • 免疫沉淀; 人类
  • 免疫印迹; 人类
Kovjazin R, Volovitz I, Kundel Y, Rosenbaum E, Medalia G, Horn G, et al. ImMucin: a novel therapeutic vaccine with promiscuous MHC binding for the treatment of MUC1-expressing tumors. Vaccine. 2011;29:4676-86 pubmed 出版商
Kovjazin R, Dubnik A, Horn G, Smorodinsky N, Hardan I, Shapira M, et al. Autoantibodies against the signal peptide domain of MUC1 in patients with multiple myeloma: Implications for disease diagnosis and prognosis. Exp Ther Med. 2012;3:1092-1098 pubmed
产品信息
产品名称 :
抗粘蛋白1糖蛋白抗体
目录号 :
4M40-M4H2
Spec:Description :
Specific for human MUC1 glycoprotein (peptide tandem repeat in MUC1 core). Affinity 1 x 108. Binds with high efficiency with different epitopes within the VNTR tandem repeat peptide region of MUC1 molecule, which have different conformations and peptide- carbohydrate compositions; reacts with VNTR20 recombinant unglycosylated fragment of MUC1 protein (and very weakly with monomeric MUC1 peptide), with deglycosylated and underglycosylated natural MUC1 (but not with completely glycosylated natural milk MUC1). Can be used for immunohistochemical staining of paraffin and frozen sections of breast, lung and ovarian tumor tissues. They may be used for staining of paraffin-embedded tissue sections fixed in neutral-buffered formalin and is compatible with commonly used histological fixatives. Also can be used in the form of enzyme conjugates for development in ELISA sandwich assays of under-glycosylated tumor-associated MUC1 mucins in human serum. They may be used in conjunction with MAbs M9E7, M8C9, M10G4 and M10H6 specific to unglycosylated VNTR region of MUC1 as capture reagents
Spec:Quantity :
1毫克
Categorization :
抗体
Spec:Clonality :
单克隆抗体
Spec:Applications :
EIA, 免疫组化
Spec:Host :
小鼠
Spec:Clone :
M4H2
Spec:Reactivity :
人类
Spec:Conjugate/Tag/Label :
未共轭
Spec:Brand/Trademark :
HyTest Ltd
Spec:Isotype :
IgG
Spec:Target :
抗粘蛋白1糖蛋白抗体
更多信息或购买 :
Hytest 产品网页
公司信息
Hytest
Intelligate 6th floor
Joukahaisenkatu 6, 20520, Turku
support@hytest.fi
http://www.hytest.fi
358-2-512-0900
公司总部: 芬兰
HyTest Ltd.位于芬兰图尔库市，为研究及工业领域生产销售高质量的免疫试剂。其产品包括心脏标志物、激素和毒素、人源蛋白、神经研究用试剂、感染和自免疾病试剂等。