产品简要
公司名称 :
Immuno-Biological Laboratories
产品类型 :
抗体
产品名称 :
sAPP-Beta-sw (6A1) Anti-Human Mouse IgG MoAb
目录 :
10321
规格 :
100微克
价格 :
499美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
6A1
反应物种 :
人类, 小鼠
应用 :
免疫印迹
文章摘录数: 7
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 3e
Li J, Chiu J, Ramanjulu M, Blass B, Pratico D. A pharmacological chaperone improves memory by reducing Aβ and tau neuropathology in a mouse model with plaques and tangles. Mol Neurodegener. 2020;15:1 pubmed 出版商
  • 免疫印迹; 小鼠; 1:50; 图 3e
Walter S, Jumpertz T, Hüttenrauch M, Ogorek I, Gerber H, Storck S, et al. The metalloprotease ADAMTS4 generates N-truncated Aβ4-x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer's disease. Acta Neuropathol. 2019;137:239-257 pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Mukadam A, Breusegem S, Seaman M. Analysis of novel endosome-to-Golgi retrieval genes reveals a role for PLD3 in regulating endosomal protein sorting and amyloid precursor protein processing. Cell Mol Life Sci. 2018;75:2613-2625 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 4a
Yan L, Deng Y, Gao J, Liu Y, Li F, Shi J, et al. Icariside II Effectively Reduces Spatial Learning and Memory Impairments in Alzheimer's Disease Model Mice Targeting Beta-Amyloid Production. Front Pharmacol. 2017;8:106 pubmed 出版商
  • 免疫印迹; 人类; 1:250; 图 8
Salta E, Sierksma A, Vanden Eynden E, De Strooper B. miR-132 loss de-represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain. EMBO Mol Med. 2016;8:1005-18 pubmed 出版商
Suh J, Romano D, Nitschke L, Herrick S, DiMarzio B, Dzhala V, et al. Loss of Ataxin-1 Potentiates Alzheimer's Pathogenesis by Elevating Cerebral BACE1 Transcription. Cell. 2019;178:1159-1175.e17 pubmed 出版商
Kizuka Y, Kitazume S, Fujinawa R, Saito T, Iwata N, Saido T, et al. An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease. EMBO Mol Med. 2015;7:175-89 pubmed 出版商
产品信息
目录号 :
10321
产品名 :
sAPP-Beta-sw (6A1) Anti-Human Mouse IgG MoAb
描述 :
This antibody can be stained in sAPPβ-sw gene transfected COS cells after fixation by 20% formalin containing methanol solution without any pretreatment by several cytochemical techniques such as Avidin Biotin Complex (ABC) Method. On the other hand, the antibody can not stained sAPPβ-wild type gene transfected COS cells by same procedure. The optimal dilution is about 5μg/ml, however, the dilution rate should be optimized by each laboratories. This antibody can be used for western blotting in concentration of about 5μg /ml. This antibody can not be used for immuno-precipitation.
抗物种 :
抗人类
宿主 :
小鼠
克隆编号 :
6A1
应用 :
免疫印迹
抗体类型 :
单克隆
抗体亚型 :
IgG3
免疫原 :
Synthetic peptide for C-Terminal of Human sAPPβ-sw (ISEVNL)
同义词 :
Soluble βAmyloid Precursor Protein -Swedish
储存 :
Lyophilized product, 5 years at 2 - 8 ℃, Solution, 2 years at -20 ℃
配方 :
冻干产品来自1% BSA在PBS含0.05% NaN3
规格 :
100微克
标价 :
499美元
说明 :
For research use only, not for use in diagnostic procedures.
公司信息
Immuno-Biological Laboratories
8201 Central Ave NE • Suite P
Minneapolis, MN 55432
mkowal@ibl-america.com
http://www.ibl-america.com
1-763-780-2955
公司总部: 美国