产品简要
公司名称 :
Immuno-Biological Laboratories
产品类型 :
抗体
产品名称 :
Amyloidβ (1-42) Anti-Human Rabbit IgG Affinity Purify
目录 :
18582
规格 :
50微克
价格 :
499美元
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类
应用 :
免疫印迹, 免疫组化
文章摘录数: 2
参考文献
Willén K, Edgar J, Hasegawa T, Tanaka N, Futter C, Gouras G. A? accumulation causes MVB enlargement and is modelled by dominant negative VPS4A. Mol Neurodegener. 2017;12:61 pubmed 出版商
Lin B, Hasegawa Y, Takane K, Koibuchi N, Cao C, Kim Mitsuyama S. High-Fat-Diet Intake Enhances Cerebral Amyloid Angiopathy and Cognitive Impairment in a Mouse Model of Alzheimer's Disease, Independently of Metabolic Disorders. J Am Heart Assoc. 2016;5: pubmed 出版商
产品信息
目录号 :
18582
产品名 :
Amyloidβ (1-42) Anti-Human Rabbit IgG Affinity Purify
描述 :
Alzheimer’s Disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein components of these plaques are beta amyloid peptide (Aβ), 40, 42 or 43 amino acid residues peptide cleaved from amyloid precursor protein by β-secretase and γ-secretase. Increased release of Aβ42 or Aβ43, which have a greater tendency to aggregate than Aβ40, occurs in individuals expressing certain genetic mutations ApoE alleles or may involve other undiscovered factors. Many researchers theorize that increased release of Aβ42/Aβ43 leads to the abnormal deposition of Aβ and the associated neurotoxicity in the brains of affected individuals.
抗物种 :
抗人类
宿主 :
应用 :
免疫组化, 免疫印迹
抗体类型 :
多克隆
免疫原 :
Synthetic peptide of a C-terminal part of Human Amyloidβ42.
同义词 :
淀粉样蛋白乙, A乙, Aβ
纯化 :
Affinity Purified with synthetic peptide.
特异性 :
Human Amyloidβ42 specific. Not cross-react with Human Amyloidβ40 or 43.
储存 :
Lyophilized product, 5 years at 2 - 8°C; Solution, 2 years at -20°C.
配方 :
冻干产品在PBS含1% BSA和0.05% NaN3
规格 :
50微克
标价 :
499美元
说明 :
For research use only, not for use in diagnostic procedures.
公司信息
Immuno-Biological Laboratories
8201 Central Ave NE • Suite P
Minneapolis, MN 55432
mkowal@ibl-america.com
www.ibl-america.com
1-763-780-2955
公司总部: 美国