产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
蛋白
产品名称 :
Human PDGF-CC Recombinant Protein, PeproTech
目录 :
100-00CC微克
规格 :
100微克
价格 :
美国648.00
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 7
参考文献
Li J, Li N, Chen Y, Hui S, Fan J, Ye B, et al. SPRY4 is responsible for pathogenesis of adolescent idiopathic scoliosis by contributing to osteogenic differentiation and melatonin response of bone marrow-derived mesenchymal stem cells. Cell Death Dis. 2019;10:805 pubmed 出版商
Ishihara J, Ishihara A, Fukunaga K, Sasaki K, White M, Briquez P, et al. Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing. Nat Commun. 2018;9:2163 pubmed 出版商
Shee K, Yang W, Hinds J, Hampsch R, Varn F, Traphagen N, et al. Therapeutically targeting tumor microenvironment-mediated drug resistance in estrogen receptor-positive breast cancer. J Exp Med. 2018;215:895-910 pubmed 出版商
Zhou X, Franklin R, Adler M, JACOX J, Bailis W, Shyer J, et al. Circuit Design Features of a Stable Two-Cell System. Cell. 2018;172:744-757.e17 pubmed 出版商
He C, Zhao C, Kumar A, Lee C, Chen M, Huang L, et al. Vasoprotective effect of PDGF-CC mediated by HMOX1 rescues retinal degeneration. Proc Natl Acad Sci U S A. 2014;111:14806-11 pubmed 出版商
Martino M, Briquez P, Ranga A, Lutolf M, Hubbell J. Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix. Proc Natl Acad Sci U S A. 2013;110:4563-8 pubmed 出版商
Van den Bergh R, Florence E, Vlieghe E, Boonefaes T, Grooten J, Houthuys E, et al. Transcriptome analysis of monocyte-HIV interactions. Retrovirology. 2010;7:53 pubmed 出版商
产品信息
产品类型 :
蛋白
产品名称 :
Human PDGF-CC Recombinant Protein, PeproTech
目录# :
100-00CC微克
规格 :
100微克
价格 :
美国648.00
克隆性 :
重组
纯度 :
HPLC, 十二烷基磺酸钠-PAGE
反应物种 :
人类
应用 :
Functional Assay: Assay-dependent
物种 :
人类
储存 :
-20°C
描述 :
The platelet-derived growth factor (PDGF) family of heparin-binding growth factors consists of five known members, denoted PDGF-AA, PDGF-BB, PDGF-AB, PDGF-CC and PDGF-DD. The mature and active form of these proteins, an anti-parallel, disulfide-linked dimer of two 12-14 kDa, polypeptide chains, is obtained through proteolytic processing of biologically inactive precursor proteins, which contain an N-terminal CUB domain and a PDGF/VEGF homologous domain. The PDGFs interact with two related protein tyrosine kinase receptors, PDGFR-alpha and PDGFR-beta, and are potent mitogens for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and certain tumor cells. They play an important role in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubules' epithelial cell development. Mature PDGFs are stored in platelet alpha-granules, and are released upon platelet activation. PDGF-AA, -AB, -BB and -CC signal primarily through the PDGFR-alpha receptor, whereas PDGF-DD interacts almost exclusively with the PDGFR-beta receptor.
格式 :
冻干
应用w/稀释 :
Functional Assay: Assay-dependent
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国