产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD34 Monoclonal Antibody (RAM34), FITC, eBioscience™
目录 :
11-0341-81
规格 :
50微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
异硫氰酸荧光素
克隆名称 :
RAM34
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫细胞化学, 流式细胞仪
更多信息或购买 :
文章摘录数: 268
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 2a
Bai L, Lyu Y, Shi G, Li K, Huang Y, Ma Y, et al. Polymerase I and transcript release factor transgenic mice show impaired function of hematopoietic stem cells. Aging (Albany NY). 2020;12:20152-20162 pubmed 出版商
  • 流式细胞仪; 小鼠
Ricci B, Tycksen E, Celik H, Belle J, Fontana F, Civitelli R, et al. Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics. elife. 2020;9: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2a
Nagai M, Noguchi R, Takahashi D, Morikawa T, Koshida K, Komiyama S, et al. Fasting-Refeeding Impacts Immune Cell Dynamics and Mucosal Immune Responses. Cell. 2019;178:1072-1087.e14 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1b
Rao T, Gupta M, Softic S, Wang L, Jang Y, Thomou T, et al. Attenuation of PKCδ enhances metabolic activity and promotes expansion of blood progenitors. EMBO J. 2018;37: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1e
Baumgartner C, Toifl S, Farlik M, Halbritter F, Scheicher R, Fischer I, et al. An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion. Cell Stem Cell. 2018;22:879-892.e6 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1
Kaufmann E, Sanz J, Dunn J, Khan N, Mendonça L, Pacis A, et al. BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis. Cell. 2018;172:176-190.e19 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2a
Guarnerio J, Mendez L, Asada N, Menon A, Fung J, Berry K, et al. A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche. Nat Commun. 2018;9:66 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 3b
Kasaai B, Caolo V, Peacock H, Lehoux S, Gomez Perdiguero E, Luttun A, et al. Erythro-myeloid progenitors can differentiate from endothelial cells and modulate embryonic vascular remodeling. Sci Rep. 2017;7:43817 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2a
Rychtarčíková Z, Lettlova S, Tomkova V, Korenkova V, Langerova L, Simonova E, et al. Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism. Oncotarget. 2017;8:6376-6398 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1b
You L, Li L, Zou J, Yan K, Belle J, Nijnik A, et al. BRPF1 is essential for development of fetal hematopoietic stem cells. J Clin Invest. 2016;126:3247-62 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 7a
Seki T, Hosaka K, Lim S, Fischer C, Honek J, Yang Y, et al. Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat. Nat Commun. 2016;7:12152 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3
Braun J, Meixner A, Brachner A, Foisner R. The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis. PLoS ONE. 2016;11:e0152278 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:400; 图 7
Miller M, Rosten P, Lemieux M, Lai C, Humphries R. Meis1 Is Required for Adult Mouse Erythropoiesis, Megakaryopoiesis and Hematopoietic Stem Cell Expansion. PLoS ONE. 2016;11:e0151584 pubmed 出版商
  • 流式细胞仪; 小鼠
Chen J, Miyanishi M, Wang S, Yamazaki S, Sinha R, Kao K, et al. Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenous perivascular niche. Nature. 2016;530:223-7 pubmed 出版商
  • 流式细胞仪; 小鼠
Cole C, Verdoni A, Ketkar S, Leight E, Russler Germain D, Lamprecht T, et al. PML-RARA requires DNA methyltransferase 3A to initiate acute promyelocytic leukemia. J Clin Invest. 2016;126:85-98 pubmed 出版商
  • 流式细胞仪; 大鼠; 图 2
Hu Y, Zhang Y, Tian K, Xun C, Wang S, Lv D. Effects of nerve growth factor and basic fibroblast growth factor dual gene modification on rat bone marrow mesenchymal stem cell differentiation into neuron-like cells in vitro. Mol Med Rep. 2016;13:49-58 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Zhang J, Li L, Baldwin A, Friedman A, Paz Priel I. Loss of IKKβ but Not NF-κB p65 Skews Differentiation towards Myeloid over Erythroid Commitment and Increases Myeloid Progenitor Self-Renewal and Functional Long-Term Hematopoietic Stem Cells. PLoS ONE. 2015;10:e0130441 pubmed 出版商
  • 流式细胞仪; 小鼠; 表 s3
Pannu J, Belle J, Forster M, Duerr C, Shen S, Kane L, et al. Ubiquitin specific protease 21 is dispensable for normal development, hematopoiesis and lymphocyte differentiation. PLoS ONE. 2015;10:e0117304 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Hu W, Dooley J, Chung S, Chandramohan D, Cimmino L, Mukherjee S, et al. miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a. Blood. 2015;125:2206-16 pubmed 出版商
  • 流式细胞仪; 小鼠
Weston W, Zayas J, Perez R, George J, Jurecic R. Dynamic equilibrium of heterogeneous and interconvertible multipotent hematopoietic cell subsets. Sci Rep. 2014;4:5199 pubmed 出版商
  • 流式细胞仪; 小鼠; 10 ug/ml; 表 1
Hittinger M, Czyz Z, Huesemann Y, Maneck M, Botteron C, Kaeufl S, et al. Molecular profiling of single Sca-1+/CD34+,- cells--the putative murine lung stem cells. PLoS ONE. 2013;8:e83917 pubmed 出版商
  • 流式细胞仪; 人类; 表 1
Alessio A, Beltrame M, Nascimento M, Vicente C, de Godoy J, Silva J, et al. Circulating progenitor and mature endothelial cells in deep vein thrombosis. Int J Med Sci. 2013;10:1746-54 pubmed 出版商
  • 流式细胞仪; 小鼠
Jenkins C, Shevchuk O, Giambra V, Lam S, Carboni J, Gottardis M, et al. IGF signaling contributes to malignant transformation of hematopoietic progenitors by the MLL-AF9 oncoprotein. Exp Hematol. 2012;40:715-723.e6 pubmed 出版商
  • 流式细胞仪; 小鼠
Ripich T, Jessberger R. SWAP-70 regulates erythropoiesis by controlling ?4 integrin. Haematologica. 2011;96:1743-52 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1, 2, 3
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  • 流式细胞仪; 小鼠; 图 1
Guibal F, Alberich Jorda M, Hirai H, Ebralidze A, Levantini E, Di Ruscio A, et al. Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia. Blood. 2009;114:5415-25 pubmed 出版商
Kalafati L, Kourtzelis I, Schulte Schrepping J, Li X, Hatzioannou A, Grinenko T, et al. Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity. Cell. 2020;183:771-785.e12 pubmed 出版商
Shao B, Wang L, Yu Y, Chen L, Gan N, Huang W. Effects of CD4+ T lymphocytes from ovariectomized mice on bone marrow mesenchymal stem cell proliferation and osteogenic differentiation. Exp Ther Med. 2020;20:84 pubmed 出版商
Patra D, Kim J, Zhang Q, Tycksen E, Sandell L. Site-1 protease ablation in the osterix-lineage in mice results in bone marrow neutrophilia and hematopoietic stem cell alterations. Biol Open. 2020;9: pubmed 出版商
Lisse T, Sharma M, Vishlaghi N, Pullagura S, Braun R. GDNF promotes hair formation and cutaneous wound healing by targeting bulge stem cells. NPJ Regen Med. 2020;5:13 pubmed 出版商
Zhang Y, Deng Z, Li Y, Yuan R, Yang M, Zhao Y, et al. Mesenchymal Stem Cells Provide Neuroprotection by Regulating Heat Stroke-Induced Brain Inflammation. Front Neurol. 2020;11:372 pubmed 出版商
Cui H, Joo S, Cho Y, Park J, Kim J, Seo C. Effect of Combining Low Temperature Plasma, Negative Pressure Wound Therapy, and Bone Marrow Mesenchymal Stem Cells on an Acute Skin Wound Healing Mouse Model. Int J Mol Sci. 2020;21: pubmed 出版商
Kuznetsova T, Smolina T, Makarenkova I, Ivanushko L, Persiyanova E, Ermakova S, et al. Immunoadjuvant Activity of Fucoidans from the Brown Alga Fucus evanescens. Mar Drugs. 2020;18: pubmed 出版商
Giannini S, Lee Sundlov M, Rivadeneyra L, Di Buduo C, Burns R, Lau J, et al. β4GALT1 controls β1 integrin function to govern thrombopoiesis and hematopoietic stem cell homeostasis. Nat Commun. 2020;11:356 pubmed 出版商
Hidalgo San Jose L, Sunshine M, Dillingham C, Chua B, Krutá M, Hong Y, et al. Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal. Cell Rep. 2020;30:69-80.e6 pubmed 出版商
Luo Z, Dai Y, Chen M, Zhu C, Wu K, Li G, et al. Silencing of RBP‑JK promotes the differentiation of bone marrow mesenchymal stem cells into vascular endothelial cells. Mol Med Rep. 2020;21:69-76 pubmed 出版商
Yamashita M, Passegue E. TNF-α Coordinates Hematopoietic Stem Cell Survival and Myeloid Regeneration. Cell Stem Cell. 2019;: pubmed 出版商
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Zhao M, Tao F, Venkatraman A, Li Z, Smith S, Unruh J, et al. N-Cadherin-Expressing Bone and Marrow Stromal Progenitor Cells Maintain Reserve Hematopoietic Stem Cells. Cell Rep. 2019;26:652-669.e6 pubmed 出版商
Chen Z, Amro E, Becker F, Holzer M, Rasa S, Njeru S, et al. Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation. J Exp Med. 2019;216:152-175 pubmed 出版商
Juban G, Saclier M, Yacoub Youssef H, Kernou A, Arnold L, Boisson C, et al. AMPK Activation Regulates LTBP4-Dependent TGF-β1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy. Cell Rep. 2018;25:2163-2176.e6 pubmed 出版商
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Singh K, Camera E, Krug L, Basu A, Pandey R, Munir S, et al. JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin. Nat Commun. 2018;9:3425 pubmed 出版商
Lee S, North K, Kim E, Jang E, Obeng E, Lu S, et al. Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations. Cancer Cell. 2018;34:225-241.e8 pubmed 出版商
Avigad Laron E, Aamar E, Enshell Seijffers D. The Mesenchymal Niche of the Hair Follicle Induces Regeneration by Releasing Primed Progenitors from Inhibitory Effects of Quiescent Stem Cells. Cell Rep. 2018;24:909-921.e3 pubmed 出版商
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Qian P, De Kumar B, He X, Nolte C, Gogol M, Ahn Y, et al. Retinoid-Sensitive Epigenetic Regulation of the Hoxb Cluster Maintains Normal Hematopoiesis and Inhibits Leukemogenesis. Cell Stem Cell. 2018;22:740-754.e7 pubmed 出版商
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Li Z, Zhang S, Cao L, Li W, Ye Y, Shi Z, et al. Tanshinone IIA and Astragaloside IV promote the angiogenesis of mesenchymal stem cell-derived endothelial cell-like cells via upregulation of Cx37, Cx40 and Cx43. Exp Ther Med. 2018;15:1847-1854 pubmed 出版商
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Huang W, Lai S, Chiu H, Chang M, Plikus M, Chan C, et al. Mobilizing Transit-Amplifying Cell-Derived Ectopic Progenitors Prevents Hair Loss from Chemotherapy or Radiation Therapy. Cancer Res. 2017;77:6083-6096 pubmed 出版商
Chaudhary J, Rath P. Microgrooved-surface topography enhances cellular division and proliferation of mouse bone marrow-derived mesenchymal stem cells. PLoS ONE. 2017;12:e0182128 pubmed 出版商
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Chacón Martínez C, Klose M, Niemann C, Glauche I, Wickström S. Hair follicle stem cell cultures reveal self-organizing plasticity of stem cells and their progeny. EMBO J. 2017;36:151-164 pubmed 出版商
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Soria Valles C, Gutierrez Fernandez A, Osorio F, Carrero D, Ferrando A, Colado E, et al. MMP-25 Metalloprotease Regulates Innate Immune Response through NF-?B Signaling. J Immunol. 2016;197:296-302 pubmed 出版商
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Pietras E, Mirantes Barbeito C, Fong S, Loeffler D, Kovtonyuk L, Zhang S, et al. Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal. Nat Cell Biol. 2016;18:607-18 pubmed 出版商
Agarwal S, Loder S, Sorkin M, Li S, Shrestha S, Zhao B, et al. Analysis of Bone-Cartilage-Stromal Progenitor Populations in Trauma Induced and Genetic Models of Heterotopic Ossification. Stem Cells. 2016;34:1692-701 pubmed 出版商
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Lee B, Koo J, Yun Jun J, Gavrilova O, Lee Y, Seo A, et al. A mouse model for a partially inactive obesity-associated human MC3R variant. Nat Commun. 2016;7:10522 pubmed 出版商
Loder S, Agarwal S, Sorkin M, Breuler C, Li J, Peterson J, et al. Lymphatic Contribution to the Cellular Niche in Heterotopic Ossification. Ann Surg. 2016;264:1174-1180 pubmed
Belle J, Petrov J, Langlais D, Robert F, Cencic R, Shen S, et al. Repression of p53-target gene Bbc3/PUMA by MYSM1 is essential for the survival of hematopoietic multipotent progenitors and contributes to stem cell maintenance. Cell Death Differ. 2016;23:759-75 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
CD34 Monoclonal Antibody (RAM34), FITC, eBioscience™
目录# :
11-0341-81
规格 :
50微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 1 µg/test
物种 :
小鼠
克隆 :
RAM34
抗体亚型 :
IgG2a, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
CD34 is a highly glycosylated monomeric with a molecular weight range of 111-115 kDa surface protein that is present on many stem cell populations. CD34 is a stem cell marker although its expression on human hematopoietic stem cells is reversible. CD34 may serve as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions. CD34 is possibly an adhesion molecule with a putative role for mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Further, CD34 could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to have a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C suggesting a putative role in signal transduction. Diseases associated with CD34 dysfunction include dermatofibrosarcoma and neurofibroma.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1 µg/test
别名 :
(E3-independent) E2 ubiquitin-conjugating enzyme R1; AU040960; CD34; CD34 antigen; CD34 molecule; CDC34; cell division cycle 34; cell division cycle 34 homolog; cluster designation 34; cluster of differentiation antigen 34; E2 ubiquitin-conjugating enzyme R1; E2-CDC34; hematopoietic progenitor cell antigen CD34; hematopoietic progenitor cell marker CD34; Mucosialin; RP11-328D5.2; sialomucin protein; type 1 transmembrane protein; UBC3; UBCH3; UBE2R1; ubiquitin carrier protein; ubiquitin conjugating enzyme E2 R1; ubiquitin-conjugating enzyme E2 R1; Ubiquitin-conjugating enzyme E2-32 kDa complementing; ubiquitin-conjugating enzyme E2-CDC34; Ubiquitin-protein ligase R1
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国