产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD36 Monoclonal Antibody (eBioNL07 (NL07)), FITC, eBioscience™
目录 :
11-0369-42
规格 :
100试验
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
异硫氰酸荧光素
克隆名称 :
eBioNL07(NL07)
反应物种 :
人类
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 15
出版应用/物种/样本/稀释 | 参考文献 |
---|---|
| |
Gruarin P, Ulliers D, Thorne R, Alessio M. Methionine 156 in the immunodominant domain of CD36 contributes to define the epitope recognized by the NL07 MoAb. Mol Cell Biochem. 2000;214:89-95 pubmed
| |
Alessio M, Greco N, Primo L, Ghigo D, Bosia A, Tandon N, et al. Platelet activation and inhibition of malarial cytoadherence by the anti-CD36 IgM monoclonal antibody NL07. Blood. 1993;82:3637-47 pubmed
| |
Alessio M, Ghigo D, Garbarino G, Geuna M, Malavasi F. Analysis of the human CD36 leucocyte differentiation antigen by means of the monoclonal antibody NL07. Cell Immunol. 1991;137:487-500 pubmed
|
产品信息
产品类型 :
抗体
产品名称 :
CD36 Monoclonal Antibody (eBioNL07 (NL07)), FITC, eBioscience™
目录# :
11-0369-42
规格 :
100试验
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 5 µL (0.25 µg)/test
物种 :
人类
克隆 :
eBioNL07(NL07)
抗体亚型 :
IgM
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
CD36 (fatty acid translocase, FAT) is an 88 kDa, ditopic glycosylated protein that belongs to the class B family of scavenger receptors. CD36 is expressed by most resting marginal zone B cells but not by follicular and B1 B cells, and is rapidly induced on Follicular B cells in vitro upon TLR and CD40 stimulation. CD36 does not affect the development of B cells, but modulates both primary and secondary antibody response. Similar to glucose transporter GLUT4, CD36 is translocated from intracellular pools to the plasma membrane following cell stimulation by insulin. In mouse, CD36 is responsible for gustatory perception of long-chain fatty acids. CD36 is preferentially found within lipid rafts, which facilitates its association with receptors, signaling and adapter molecules. CD36 binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. Further, CD36 may function as a cell adhesion molecule and directly mediates cyto-adherence of Plasmodium falciparum parasitized erythrocytes. Mutations in the CD36 gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants encoding the CD36 protein have been found.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 5 µL (0.25 µg)/test
别名 :
adipocyte membrane protein; BDPLT10; Cd36; CD36 antigen; CD36 antigen (collagen type I receptor, thrombospondin receptor); CD36 molecule; CD36 molecule (thrombospondin receptor); CD36 protein; CHDS7; cluster determinant 36; collagen type I receptor thrombospondin receptor; collagen type I receptor, thrombospondin receptor; FAT; FAT/CD36; fatty acid translocase; fatty acid translocase/CD36; fatty acid transport protein; glycoprotein IIIb; GP3B; GP4; GPIIIB; GPIV; I79_011940; Leukocyte differentiation antigen CD36; PAS IV; PAS4; PAS-4; PAS-4 protein; PASIV; Platelet collagen receptor; Platelet glycoprotein 4; platelet glycoprotein IV; Scarb3; scavenger receptor class B, member 3; SR-B3; Thrombospondin receptor
更多信息或购买 :
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