产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD40 Monoclonal Antibody (HM40-3), FITC, eBioscience™
目录 :
11-0402-86
规格 :
1毫克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
仓鼠
共轭标签 :
异硫氰酸荧光素
克隆名称 :
HM40-3
反应物种 :
小鼠, 大鼠
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 62
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 3
Sun H, Zhang J, Chen F, Chen X, Zhou Z, Wang H. Activation of RAW264.7 macrophages by the polysaccharide from the roots of Actinidia eriantha and its molecular mechanisms. Carbohydr Polym. 2015;121:388-402 pubmed 出版商
Schoeler K, Aufschnaiter A, Messner S, Derudder E, Herzog S, Villunger A, et al. TET enzymes control antibody production and shape the mutational landscape in germinal centre B cells. FEBS J. 2019;286:3566-3581 pubmed 出版商
Li Q, Liu C, Yue R, El Ashram S, Wang J, He X, et al. cGAS/STING/TBK1/IRF3 Signaling Pathway Activates BMDCs Maturation Following Mycobacterium bovis Infection. Int J Mol Sci. 2019;20: pubmed 出版商
Willis S, Tellier J, Liao Y, Trezise S, Light A, O Donnell K, et al. Environmental sensing by mature B cells is controlled by the transcription factors PU.1 and SpiB. Nat Commun. 2017;8:1426 pubmed 出版商
Wang H, Lin J, Zeng L, Ouyang C, Ran P, Yang P, et al. Der f 31, a novel allergen from Dermatophagoides farinae, activates epithelial cells and enhances lung-resident group 2 innate lymphoid cells. Sci Rep. 2017;7:8519 pubmed 出版商
Karim A, Reba S, Li Q, Boom W, Rojas R. Toll like Receptor 2 engagement on CD4+ T cells promotes TH9 differentiation and function. Eur J Immunol. 2017;47:1513-1524 pubmed 出版商
Hawkins K, Demars K, Alexander J, de Leon L, Pacheco S, Graves C, et al. Targeting resolution of neuroinflammation after ischemic stroke with a lipoxin A4 analog: Protective mechanisms and long-term effects on neurological recovery. Brain Behav. 2017;7:e00688 pubmed 出版商
Wang H, Mo L, Xiao X, An S, Liu X, Ba J, et al. Pplase of Dermatophagoides farinae promotes ovalbumin-induced airway allergy by modulating the functions of dendritic cells in a mouse model. Sci Rep. 2017;7:43322 pubmed 出版商
Wang H, Hu W, Liang Z, Zeng L, Li J, Yan H, et al. Thiol peroxiredoxin, a novel allergen from Bombyx mori, modulates functions of macrophages and dendritic cells. Am J Transl Res. 2016;8:5320-5329 pubmed
Cicchelero L, Denies S, Devriendt B, de Rooster H, Sanders N. Can dendritic cells improve whole cancer cell vaccines based on immunogenically killed cancer cells?. Oncoimmunology. 2015;4:e1048413 pubmed
Frodermann V, van Duijn J, van Pel M, Van Santbrink P, Bot I, Kuiper J, et al. Mesenchymal Stem Cells Reduce Murine Atherosclerosis Development. Sci Rep. 2015;5:15559 pubmed 出版商
Tsuji R, Koizumi H, Aoki D, Watanabe Y, Sugihara Y, Matsushita Y, et al. Lignin-rich enzyme lignin (LREL), a cellulase-treated lignin-carbohydrate derived from plants, activates myeloid dendritic cells via Toll-like receptor 4 (TLR4). J Biol Chem. 2015;290:4410-21 pubmed 出版商
Song L, Yang M, Knoff J, Wu T, Hung C. Cancer immunotherapy employing an innovative strategy to enhance CD4+ T cell help in the tumor microenvironment. PLoS ONE. 2014;9:e115711 pubmed 出版商
Zhang X, Liu Y, Zhang G, Shi J, Zhang X, Zheng X, et al. Synergic silencing of costimulatory molecules prevents cardiac allograft rejection. J Transl Med. 2014;12:142 pubmed 出版商
Nijhuis L, Olivier B, Dhawan S, Hilbers F, Boon L, Wolkers M, et al. Adrenergic ?2 receptor activation stimulates anti-inflammatory properties of dendritic cells in vitro. PLoS ONE. 2014;9:e85086 pubmed 出版商
Kamachi F, Harada N, Usui Y, Sakanishi T, Ishii N, Okumura K, et al. OX40 ligand regulates splenic CD8? dendritic cell-induced Th2 responses in vivo. Biochem Biophys Res Commun. 2014;444:235-40 pubmed 出版商
Murakami R, Denda Nagai K, Hashimoto S, Nagai S, Hattori M, Irimura T. A unique dermal dendritic cell subset that skews the immune response toward Th2. PLoS ONE. 2013;8:e73270 pubmed 出版商
Donius L, Orlando C, Weis J, Weis J. Generation of a novel Cr2 gene allele by homologous recombination that abrogates production of Cr2 but is sufficient for expression of Cr1. Immunobiology. 2014;219:53-63 pubmed 出版商
Martín López A, Acosta López L, García Camacho F, Contreras Gómez A, Molina Grima E. Co-culture of the 55-6 B cell hybridoma with the EL-4 thymoma cell. Effect on cell growth and monoclonal antibody production. Cytotechnology. 2013;65:655-62 pubmed 出版商
Seillet C, Rouquié N, Foulon E, Douin Echinard V, Krust A, Chambon P, et al. Estradiol promotes functional responses in inflammatory and steady-state dendritic cells through differential requirement for activation function-1 of estrogen receptor ?. J Immunol. 2013;190:5459-70 pubmed 出版商
Rehman A, Hemmert K, Ochi A, Jamal M, Henning J, Barilla R, et al. Role of fatty-acid synthesis in dendritic cell generation and function. J Immunol. 2013;190:4640-9 pubmed 出版商
Innes C, Hesse J, Palii S, Helmink B, Holub A, Sleckman B, et al. DNA damage activates a complex transcriptional response in murine lymphocytes that includes both physiological and cancer-predisposition programs. BMC Genomics. 2013;14:163 pubmed 出版商
Masani S, Han L, Yu K. Apurinic/apyrimidinic endonuclease 1 is the essential nuclease during immunoglobulin class switch recombination. Mol Cell Biol. 2013;33:1468-73 pubmed 出版商
Weinberger E, Himly M, Myschik J, Hauser M, Altmann F, Isakovic A, et al. Generation of hypoallergenic neoglycoconjugates for dendritic cell targeted vaccination: a novel tool for specific immunotherapy. J Control Release. 2013;165:101-9 pubmed 出版商
Arcipowski K, Bishop G. TRAF binding is required for a distinct subset of in vivo B cell functions of the oncoprotein LMP1. J Immunol. 2012;189:5165-70 pubmed 出版商
Ramon S, Bancos S, Thatcher T, Murant T, Moshkani S, Sahler J, et al. Peroxisome proliferator-activated receptor ? B cell-specific-deficient mice have an impaired antibody response. J Immunol. 2012;189:4740-7 pubmed 出版商
Chu Y, Soberon V, Glockner L, Beyaert R, Massoumi R, Van Loo G, et al. A20 and CYLD do not share significant overlapping functions during B cell development and activation. J Immunol. 2012;189:4437-43 pubmed 出版商
de Andres B, Prado C, Palacios B, Alía M, Jagtap S, Serrano N, et al. Dynamics of the splenic innate-like CD19?CD45Rlo cell population from adult mice in homeostatic and activated conditions. J Immunol. 2012;189:2300-8 pubmed 出版商
Kamphuis T, Meijerhof T, Stegmann T, Lederhofer J, Wilschut J, de Haan A. Immunogenicity and protective capacity of a virosomal respiratory syncytial virus vaccine adjuvanted with monophosphoryl lipid A in mice. PLoS ONE. 2012;7:e36812 pubmed 出版商
Jounai K, Ikado K, Sugimura T, Ano Y, Braun J, Fujiwara D. Spherical lactic acid bacteria activate plasmacytoid dendritic cells immunomodulatory function via TLR9-dependent crosstalk with myeloid dendritic cells. PLoS ONE. 2012;7:e32588 pubmed 出版商
Hampel F, Ehrenberg S, Hojer C, Draeseke A, Marschall Schröter G, Kühn R, et al. CD19-independent instruction of murine marginal zone B-cell development by constitutive Notch2 signaling. Blood. 2011;118:6321-31 pubmed 出版商
Ebensen T, Libanova R, Schulze K, Yevsa T, Morr M, Guzman C. Bis-(3',5')-cyclic dimeric adenosine monophosphate: strong Th1/Th2/Th17 promoting mucosal adjuvant. Vaccine. 2011;29:5210-20 pubmed 出版商
Boué J, Blanpied C, Brousset P, Vergnolle N, Dietrich G. Endogenous opioid-mediated analgesia is dependent on adaptive T cell response in mice. J Immunol. 2011;186:5078-84 pubmed 出版商
Cao S, Li Y, Ye J, Yang X, Chen L, Liu X, et al. Japanese encephalitis Virus wild strain infection suppresses dendritic cells maturation and function, and causes the expansion of regulatory T cells. Virol J. 2011;8:39 pubmed 出版商
Yabu M, Shime H, Hara H, Saito T, Matsumoto M, Seya T, et al. IL-23-dependent and -independent enhancement pathways of IL-17A production by lactic acid. Int Immunol. 2011;23:29-41 pubmed 出版商
Chu Y, Vahl J, Kumar D, Heger K, Bertossi A, Wójtowicz E, et al. B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice. Blood. 2011;117:2227-36 pubmed 出版商
DRUTMAN S, Trombetta E. Dendritic cells continue to capture and present antigens after maturation in vivo. J Immunol. 2010;185:2140-6 pubmed 出版商
Sugita S, Horie S, Yamada Y, Mochizuki M. Inhibition of B-cell activation by retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2010;51:5783-8 pubmed 出版商
Eidenschenk C, Crozat K, Krebs P, Arens R, Popkin D, Arnold C, et al. Flt3 permits survival during infection by rendering dendritic cells competent to activate NK cells. Proc Natl Acad Sci U S A. 2010;107:9759-64 pubmed 出版商
Nesbeth Y, Martinez D, Toraya S, Scarlett U, Cubillos Ruiz J, Rutkowski M, et al. CD4+ T cells elicit host immune responses to MHC class II-negative ovarian cancer through CCL5 secretion and CD40-mediated licensing of dendritic cells. J Immunol. 2010;184:5654-62 pubmed 出版商
Hirata Y, Hamanaka S, Onodera M. Transactivation of the dopamine receptor 3 gene by a single provirus integration results in development of B-cell lymphoma in transgenic mice generated from retrovirally transduced embryonic stem cells. Blood. 2010;115:3930-8 pubmed 出版商
Gulani J, Norbury C, Bonneau R, Beckwith C. The effect of Helicobacter hepaticus infection on immune responses specific to herpes simplex virus type 1 and characteristics of dendritic cells. Comp Med. 2009;59:534-44 pubmed
Gaudenzio N, Espagnolle N, Mars L, Liblau R, Valitutti S, Espinosa E. Cell-cell cooperation at the T helper cell/mast cell immunological synapse. Blood. 2009;114:4979-88 pubmed 出版商
Walsh K, Brady M, Finlay C, Boon L, Mills K. Infection with a helminth parasite attenuates autoimmunity through TGF-beta-mediated suppression of Th17 and Th1 responses. J Immunol. 2009;183:1577-86 pubmed 出版商
Zietara N, Łyszkiewicz M, Gekara N, Puchałka J, dos Santos V, Hunt C, et al. Absence of IFN-beta impairs antigen presentation capacity of splenic dendritic cells via down-regulation of heat shock protein 70. J Immunol. 2009;183:1099-109 pubmed 出版商
Turner J, Langley R, Johnston K, Gentil K, Ford L, Wu B, et al. Wolbachia lipoprotein stimulates innate and adaptive immunity through Toll-like receptors 2 and 6 to induce disease manifestations of filariasis. J Biol Chem. 2009;284:22364-78 pubmed 出版商
Hong Z, Huang X, Yin Z, Zhao W, Wang X. Immunosuppressive function of bone marrow mesenchymal stem cells on acute rejection of liver allografts in rats. Transplant Proc. 2009;41:403-9 pubmed 出版商
Silva Flannery L, Cabrera Mora M, Dickherber M, Moreno A. Polymeric linear Peptide chimeric vaccine-induced antimalaria immunity is associated with enhanced in vitro antigen loading. Infect Immun. 2009;77:1798-806 pubmed 出版商
Babbe H, McMenamin J, Hobeika E, Wang J, Rodig S, Reth M, et al. Genomic instability resulting from Blm deficiency compromises development, maintenance, and function of the B cell lineage. J Immunol. 2009;182:347-60 pubmed
Hadeiba H, Sato T, Habtezion A, Oderup C, Pan J, Butcher E. CCR9 expression defines tolerogenic plasmacytoid dendritic cells able to suppress acute graft-versus-host disease. Nat Immunol. 2008;9:1253-60 pubmed 出版商
Hussain S, He P, Subleski J, Hofseth L, Trivers G, Mechanic L, et al. Nitric oxide is a key component in inflammation-accelerated tumorigenesis. Cancer Res. 2008;68:7130-6 pubmed 出版商
Lee J, Dollins C, Boczkowski D, Sullenger B, Nair S. Activated B cells modified by electroporation of multiple mRNAs encoding immune stimulatory molecules are comparable to mature dendritic cells in inducing in vitro antigen-specific T-cell responses. Immunology. 2008;125:229-40 pubmed 出版商
de Haas A, Boddeke H, Biber K. Region-specific expression of immunoregulatory proteins on microglia in the healthy CNS. Glia. 2008;56:888-94 pubmed 出版商
Douin Echinard V, Laffont S, Seillet C, Delpy L, Krust A, Chambon P, et al. Estrogen receptor alpha, but not beta, is required for optimal dendritic cell differentiation and [corrected] CD40-induced cytokine production. J Immunol. 2008;180:3661-9 pubmed
Tenno M, Ohtsubo K, Hagen F, Ditto D, Zarbock A, Schaerli P, et al. Initiation of protein O glycosylation by the polypeptide GalNAcT-1 in vascular biology and humoral immunity. Mol Cell Biol. 2007;27:8783-96 pubmed
Elftman M, Norbury C, Bonneau R, Truckenmiller M. Corticosterone impairs dendritic cell maturation and function. Immunology. 2007;122:279-90 pubmed
Nabekura T, Nagasawa T, Nakauchi H, Onodera M. An immunotherapy approach with dendritic cells genetically modified to express the tumor-associated antigen, HER2. Cancer Immunol Immunother. 2008;57:611-22 pubmed
Munroe M, Bishop G. A costimulatory function for T cell CD40. J Immunol. 2007;178:671-82 pubmed
Ishiyama K, Ohdan H, Tokita D, Shishida M, Tanaka Y, Irei T, et al. Induction of endotoxin tolerance inhibits alloimmune responses. Transpl Immunol. 2006;16:158-65 pubmed
Nishikawa Y, Hikida M, Magari M, Kanayama N, Mori M, Kitamura H, et al. Establishment of lymphotoxin beta receptor signaling-dependent cell lines with follicular dendritic cell phenotypes from mouse lymph nodes. J Immunol. 2006;177:5204-14 pubmed
Rush J, Liu M, Odegard V, Unniraman S, Schatz D. Expression of activation-induced cytidine deaminase is regulated by cell division, providing a mechanistic basis for division-linked class switch recombination. Proc Natl Acad Sci U S A. 2005;102:13242-7 pubmed
Andrade R, Portillo J, Wessendarp M, Subauste C. CD40 signaling in macrophages induces activity against an intracellular pathogen independently of gamma interferon and reactive nitrogen intermediates. Infect Immun. 2005;73:3115-23 pubmed
产品信息
产品类型 :
抗体
产品名称 :
CD40 Monoclonal Antibody (HM40-3), FITC, eBioscience™
目录# :
11-0402-86
规格 :
1毫克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
亚美尼亚仓鼠
反应物种 :
小鼠, 大鼠
应用 :
Flow Cytometry: 1 µg/test
物种 :
小鼠, 大鼠
克隆 :
HM40-3
抗体亚型 :
IgM, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
The CD40 antigen is a single chain glycoprotein that is known to be a member of the tumor necrosis factor/nerve growth factor superfamily and shows a significant homology to the Hodgkin's disease associated antigen, CD30. CD40 is present on all B cells except plasma cells and is also found on some epithelial cells, carcinomas and lymphoid dendritic cells. CD40 has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of CD40, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with CD40 and serves as a mediator of the signal transduction. The interaction of CD40 and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of CD40 encoding distinct isoforms have been reported. Diseases associated with CD40 dysfunction include Type 3 Hyper-Igm immunodeficiency and CD40 ligand deficiency.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1 µg/test
别名 :
AI326936; B cell surface antigen CD40; B cell-associated molecule; B-cell surface antigen CD40; Bp50; CD antigen CD40; Cd40; CD40 antigen; CD40 antigen (TNF receptor superfamily member 5); CD40 antigen, TNF receptor superfamily member 5; CD40 molecule; CD40 molecule, TNF receptor superfamily member 5; CD40L receptor; CDw40; GP39; HIGM1; I79_006806; IGM; IMD3; Immunoglobulin M; ImmunoglobulinM; membrane protein CD40; MGC9013; p50; receptor for ligand CD154; sCD40; soluble CD40; T-BAM; T-cell differentiation antigen; Tnfrsf5; TRAP; tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily, member 5
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国