产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD45 Monoclonal Antibody (30-F11), FITC, eBioscience
目录 :
11-0451-81
规格 :
50微克
价格 :
美国53.75
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
异硫氰酸荧光素
克隆名称 :
30-F11
反应物种 :
小鼠, 大鼠
应用 :
免疫组化, 流式细胞仪
更多信息或购买 :
文章摘录数: 455
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 1:200; 图 s1b
Ambrosi T, Sinha R, Steininger H, Hoover M, Murphy M, Koepke L, et al. Distinct skeletal stem cell types orchestrate long bone skeletogenesis. elife. 2021;10: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2a
Kastenschmidt J, Coulis G, Farahat P, Pham P, Rios R, Cristal T, et al. A stromal progenitor and ILC2 niche promotes muscle eosinophilia and fibrosis-associated gene expression. Cell Rep. 2021;35:108997 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1a
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  • 流式细胞仪; 小鼠; 1:100; 图 1ba
Ahmed M, El Sayed A, Chen H, Zhao R, Yusuf M, Zuo Q, et al. Comparison between curcumin and all-trans retinoic acid in the osteogenic differentiation of mouse bone marrow mesenchymal stem cells. Exp Ther Med. 2019;17:4154-4166 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 8b
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  • 流式细胞仪; 小鼠; 图 6c
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  • 流式细胞仪; 小鼠; 图 7
Xiong J, Zhou M, Wang Y, Chen L, Xu W, Wang Y, et al. Protein Kinase D2 Protects against Acute Colitis Induced by Dextran Sulfate Sodium in Mice. Sci Rep. 2016;6:34079 pubmed 出版商
  • 免疫组化; 小鼠; 1:250; 图 8
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  • 免疫组化; 小鼠; 1:100; 图 s2
Yao Y, Norris E, Mason C, Strickland S. Laminin regulates PDGFR?(+) cell stemness and muscle development. Nat Commun. 2016;7:11415 pubmed 出版商
  • 流式细胞仪; 大鼠; 图 2
Hu Y, Zhang Y, Tian K, Xun C, Wang S, Lv D. Effects of nerve growth factor and basic fibroblast growth factor dual gene modification on rat bone marrow mesenchymal stem cell differentiation into neuron-like cells in vitro. Mol Med Rep. 2016;13:49-58 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
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  • 流式细胞仪; 小鼠; 图 s3
Ding X, Lucas T, Marcuzzi G, Pfister H, Eming S. Distinct functions of epidermal and myeloid-derived VEGF-A in skin tumorigenesis mediated by HPV8. Cancer Res. 2015;75:330-43 pubmed 出版商
  • 流式细胞仪; 小鼠
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  • 流式细胞仪; 小鼠; 1:200
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  • 流式细胞仪; 小鼠; 图 1
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  • 流式细胞仪; 小鼠
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Lin Z, Xi L, Chen S, Tao J, Wang Y, Chen X, et al. Uptake and trafficking of different sized PLGA nanoparticles by dendritic cells in imiquimod-induced psoriasis-like mice model. Acta Pharm Sin B. 2021;11:1047-1055 pubmed 出版商
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Gallot Y, Straughn A, Bohnert K, Xiong G, Hindi S, Kumar A. MyD88 is required for satellite cell-mediated myofiber regeneration in dystrophin-deficient mdx mice. Hum Mol Genet. 2018;27:3449-3463 pubmed 出版商
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Asosingh K, Weiss K, Queisser K, Wanner N, Yin M, Aronica M, et al. Endothelial cells in the innate response to allergens and initiation of atopic asthma. J Clin Invest. 2018;128:3116-3128 pubmed 出版商
Rosin J, Kurrasch D. In utero electroporation induces cell death and alters embryonic microglia morphology and expression signatures in the developing hypothalamus. J Neuroinflammation. 2018;15:181 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
CD45 Monoclonal Antibody (30-F11), FITC, eBioscience
目录# :
11-0451-81
规格 :
50微克
价格 :
美国53.75
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.5 µg/test
物种 :
小鼠
克隆 :
30-F11
抗体亚型 :
IgG2b, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues. CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains. CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells. CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45 has been shown to be an essential regulator of T- and B-cell antigen receptor signaling and suppresses JAK kinases to regulate cytokine receptor signaling. CD45 is also important in promoting cell survival by modulating integrin-mediated signal transduction pathway, DNA fragmentation during apoptosis and inhibition or upregulation of various immunological functions.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.5 µg/test
别名 :
B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen; T220 and B220
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国