产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
TCR gamma/delta Monoclonal Antibody (eBioGL3 (GL-3, GL3)), FITC, eBioscience™
目录 :
11-5711-85
规格 :
500微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
仓鼠
共轭标签 :
异硫氰酸荧光素
克隆名称 :
eBioGL3(GL-3, GL3)
反应物种 :
小鼠
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 45
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 1:200; 图 s8
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Akitsu A, Kakuta S, Saijo S, Iwakura Y. Rag2-deficient IL-1 Receptor Antagonist-deficient Mice Are a Novel Colitis Model in Which Innate Lymphoid Cell-derived IL-17 Is Involved in the Pathogenesis. Exp Anim. 2014;63:235-46 pubmed
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Shan M, You R, Yuan X, Frazier M, Porter P, Seryshev A, et al. Agonistic induction of PPAR? reverses cigarette smoke-induced emphysema. J Clin Invest. 2014;124:1371-81 pubmed 出版商
Yamamoto H, Nakamura Y, Sato K, Takahashi Y, Nomura T, Miyasaka T, et al. Defect of CARD9 leads to impaired accumulation of gamma interferon-producing memory phenotype T cells in lungs and increased susceptibility to pulmonary infection with Cryptococcus neoformans. Infect Immun. 2014;82:1606-15 pubmed 出版商
Lee P, Puppi M, Schluns K, Yu Lee L, Dong C, Lacorazza H. The transcription factor E74-like factor 4 suppresses differentiation of proliferating CD4+ T cells to the Th17 lineage. J Immunol. 2014;192:178-88 pubmed 出版商
Nakatsuka R, Matsuoka Y, Uemura Y, Sumide K, Iwaki R, Takahashi M, et al. Mouse dental pulp stem cells support human umbilical cord blood-derived hematopoietic stem/progenitor cells in vitro. Cell Transplant. 2015;24:97-113 pubmed 出版商
Grishkan I, Ntranos A, Calabresi P, Gocke A. Helper T cells down-regulate CD4 expression upon chronic stimulation giving rise to double-negative T cells. Cell Immunol. 2013;284:68-74 pubmed 出版商
Guo Y, Sun X, Shibata K, Yamada H, Muta H, Podack E, et al. CD30 is required for activation of a unique subset of interleukin-17A-producing ?? T cells in innate immunity against Mycobacterium bovis Bacillus Calmette-Guerin infection. Infect Immun. 2013;81:3923-34 pubmed 出版商
Kole A, He J, Rivollier A, Silveira D, Kitamura K, Maloy K, et al. Type I IFNs regulate effector and regulatory T cell accumulation and anti-inflammatory cytokine production during T cell-mediated colitis. J Immunol. 2013;191:2771-9 pubmed 出版商
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Jiang J, Champion C, Wei B, Liu G, Kelly K. CD8?CXCR5? T cells regulate pathology in the genital tract. Infect Dis Obstet Gynecol. 2013;2013:813238 pubmed 出版商
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Cheng P, Liu T, Zhou W, Zhuang Y, Peng L, Zhang J, et al. Role of gamma-delta T cells in host response against Staphylococcus aureus-induced pneumonia. BMC Immunol. 2012;13:38 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
TCR gamma/delta Monoclonal Antibody (eBioGL3 (GL-3, GL3)), FITC, eBioscience™
目录# :
11-5711-85
规格 :
500微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
亚美尼亚仓鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.5 µg/test
物种 :
小鼠
克隆 :
eBioGL3(GL-3, GL3)
抗体亚型 :
IgG
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
TCR gamma/delta (T-cell receptor gamma/delta) are specialized T-cells in the immune system. The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors. Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome. Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The autoantibodies block TH1-mediated inflammatory auto-destructive reactions and are believed to be a method by which the immune system compensates for disease. Most human T cells express the TCR alpha-beta and either CD4 or CD8 molecule (single positive, SP). However, a small number of T cells lack both CD4 and CD8 (double negative, DN). Increased percentages of alpha-beta DN T cells have been identified in some autoimmune and immunodeficiency disorders. Gamma-delta T cells are primarily found within the epithelium. They show less TCR diversity and recognize antigens differently than alpha-beta T cells. Subsets of gamma-delta T cells have shown antitumor and immunoregulatory activity.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.5 µg/test
别名 :
RGD1311300; similar to T cell receptor V delta 6; T cell receptor gamma locus; T3/TCR complex; TCR delta gamma; TCR gamma/delta; TCR-CD3 complex; Tcrg; Trg; Trg@
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国