产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IgM Monoclonal Antibody (II/41), FITC, eBioscience™
目录 :
11-5790-81
规格 :
50微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
异硫氰酸荧光素
克隆名称 :
II/41
反应物种 :
小鼠
应用 :
免疫组化, 免疫细胞化学, 流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 37
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 1b
Wang S, Xia P, Chen Y, Huang G, Xiong Z, Liu J, et al. Natural Killer-like B Cells Prime Innate Lymphocytes against Microbial Infection. Immunity. 2016;45:131-44 pubmed 出版商
Fallet B, Hao Y, Florova M, Cornille K, de Los Aires A, Girelli Zubani G, et al. Chronic Viral Infection Promotes Efficient Germinal Center B Cell Responses. Cell Rep. 2020;30:1013-1026.e7 pubmed 出版商
Schoeler K, Aufschnaiter A, Messner S, Derudder E, Herzog S, Villunger A, et al. TET enzymes control antibody production and shape the mutational landscape in germinal centre B cells. FEBS J. 2019;286:3566-3581 pubmed 出版商
Weng Q, Hu F, Zhang M, Dong Y, Lv C, Wang Y, et al. A protocol for generating induced T cells by reprogramming B cells in vivo. Cell Regen (Lond). 2018;7:7-15 pubmed 出版商
Stark A, Chandra A, Chakraborty K, Alam R, Carbonaro V, Clark J, et al. PI3Kδ hyper-activation promotes development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner. Nat Commun. 2018;9:3174 pubmed 出版商
Wang X, Zhang Y, Wang Z, Liu X, Zhu G, Han G, et al. Anti?IL?39 (IL?23p19/Ebi3) polyclonal antibodies ameliorate autoimmune symptoms in lupus?like mice. Mol Med Rep. 2017;: pubmed 出版商
Schweighoffer E, Nys J, Vanes L, Smithers N, Tybulewicz V. TLR4 signals in B lymphocytes are transduced via the B cell antigen receptor and SYK. J Exp Med. 2017;214:1269-1280 pubmed 出版商
Ikawa T, Masuda K, Endo T, Endo M, Isono K, Koseki Y, et al. Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of the B-lineage program. Genes Dev. 2016;30:2475-2485 pubmed
Lund P, Elias J, Davis M. Global Analysis of O-GlcNAc Glycoproteins in Activated Human T Cells. J Immunol. 2016;197:3086-3098 pubmed
van der Velden D, Lagraauw H, Wezel A, Launay P, Kuiper J, Huizinga T, et al. Mast cell depletion in the preclinical phase of collagen-induced arthritis reduces clinical outcome by lowering the inflammatory cytokine profile. Arthritis Res Ther. 2016;18:138 pubmed 出版商
Cheong T, Compagno M, Chiarle R. Editing of mouse and human immunoglobulin genes by CRISPR-Cas9 system. Nat Commun. 2016;7:10934 pubmed 出版商
Lu G, Duan J, Shu S, Wang X, Gao L, Guo J, et al. Ligase I and ligase III mediate the DNA double-strand break ligation in alternative end-joining. Proc Natl Acad Sci U S A. 2016;113:1256-60 pubmed 出版商
Tomokatsu I, Masuda K, Huijskens M, Satoh R, Kakugawa K, Agata Y, et al. Induced Developmental Arrest of Early Hematopoietic Progenitors Leads to the Generation of Leukocyte Stem Cells. Stem Cell Reports. 2015;5:716-27 pubmed
Canver M, SMITH E, Sher F, Pinello L, Sanjana N, Shalem O, et al. BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis. Nature. 2015;527:192-7 pubmed 出版商
Palmer V, Aziz Seible R, Kassmeier M, Rothermund M, Perry G, Swanson P. VprBP Is Required for Efficient Editing and Selection of Igκ+ B Cells, but Is Dispensable for Igλ+ and Marginal Zone B Cell Maturation and Selection. J Immunol. 2015;195:1524-37 pubmed 出版商
Weindel C, Richey L, Bolland S, Mehta A, Kearney J, Huber B. B cell autophagy mediates TLR7-dependent autoimmunity and inflammation. Autophagy. 2015;11:1010-24 pubmed 出版商
Li W, Yu R, Ma B, Yang Y, Jiao X, Liu Y, et al. Core fucosylation of IgG B cell receptor is required for antigen recognition and antibody production. J Immunol. 2015;194:2596-606 pubmed 出版商
Khoo L, Thiam C, Soh S, Angeli V. Splenic extrafollicular reactions and BM plasma cells sustain IgM response associated with hypercholesterolemia. Eur J Immunol. 2015;45:1300-12 pubmed 出版商
Cho J, Seo J, Lim C, Yang L, Shiratsuchi T, Lee M, et al. Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis. Cell Death Differ. 2015;22:1437-50 pubmed 出版商
Vettermann C, Timblin G, Lim V, Lai E, Schlissel M. The proximal J kappa germline-transcript promoter facilitates receptor editing through control of ordered recombination. PLoS ONE. 2015;10:e0113824 pubmed 出版商
Reynolds A, Kuraoka M, Kelsoe G. Natural IgM is produced by CD5- plasma cells that occupy a distinct survival niche in bone marrow. J Immunol. 2015;194:231-42 pubmed 出版商
Kläsener K, Maity P, Hobeika E, Yang J, Reth M. B cell activation involves nanoscale receptor reorganizations and inside-out signaling by Syk. elife. 2014;3:e02069 pubmed 出版商
Rouaud P, Saintamand A, Saad F, Carrion C, Lecardeur S, Cogne M, et al. Elucidation of the enigmatic IgD class-switch recombination via germline deletion of the IgH 3' regulatory region. J Exp Med. 2014;211:975-85 pubmed 出版商
Olive V, SABIO E, Bennett M, De Jong C, Biton A, McGann J, et al. A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis. elife. 2013;2:e00822 pubmed 出版商
Jones D, Jones M, Deiulio G, Racine R, MacNamara K, Winslow G. B cell activating factor inhibition impairs bacterial immunity by reducing T cell-independent IgM secretion. Infect Immun. 2013;81:4490-7 pubmed 出版商
Carofino B, Ayanga B, Justice M. A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL). Dis Model Mech. 2013;6:1494-506 pubmed 出版商
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Yu M, Chen Y, He Y, Podd A, Fu G, Wright J, et al. Critical role of B cell lymphoma 10 in BAFF-regulated NF-?B activation and survival of anergic B cells. J Immunol. 2012;189:5185-93 pubmed 出版商
McNamee E, Masterson J, Jedlicka P, Collins C, Williams I, Rivera Nieves J. Ectopic lymphoid tissue alters the chemokine gradient, increases lymphocyte retention and exacerbates murine ileitis. Gut. 2013;62:53-62 pubmed 出版商
Todd E, Deady L, Morley S. The actin-bundling protein L-plastin is essential for marginal zone B cell development. J Immunol. 2011;187:3015-25 pubmed 出版商
Wuerzberger Davis S, Chen Y, Yang D, Kearns J, Bates P, Lynch C, et al. Nuclear export of the NF-?B inhibitor I?B? is required for proper B cell and secondary lymphoid tissue formation. Immunity. 2011;34:188-200 pubmed 出版商
Racine R, McLaughlin M, Jones D, Wittmer S, MacNamara K, Woodland D, et al. IgM production by bone marrow plasmablasts contributes to long-term protection against intracellular bacterial infection. J Immunol. 2011;186:1011-21 pubmed 出版商
Santiago M, Benitez R, Montano M, Hasenkrug K, Greene W. Innate retroviral restriction by Apobec3 promotes antibody affinity maturation in vivo. J Immunol. 2010;185:1114-23 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
IgM Monoclonal Antibody (II/41), FITC, eBioscience™
目录# :
11-5790-81
规格 :
50微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.25 µg/test, Immunocytochemistry: 10 µg/mL, Immunohistochemistry: Assay-Dependent
物种 :
小鼠
克隆 :
II/41
抗体亚型 :
IgG2a, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
IgM (Immunoglobulin M) is expressed intracellularly during the early stages of B lymphopoiesis, and then on the surface of more mature B cells in the bone marrow and peripheral B cells. The isotype of a primary antibody and its application can result in background staining. Primary antibody background noise can be caused by binding to Fc receptors on target cells; by non-specific interactions with cellular proteins, carbohydrates, and lipids; or by cell autofluorescence. Isotype control antibodies can act as negative controls to help differentiate non-specific background signal from specific antibody signal because they have no relevant specificity to a target antigen. While isotype controls are most commonly used in flow cytometry, they are also useful in other applications such as chromatin immunoprecipitation (ChIP), immunohistochemistry, and gel shifts. Isotype controls should match with the primary antibody species and isotype so that the level of specific staining by the primary antibody may be accurately determined. If using directly labeled primary antibodies, the isotype control works best if conjugated with the same label as the test antibody.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.25 µg/test, Immunocytochemistry: 10 µg/mL, Immunohistochemistry: Assay-Dependent
别名 :
AGM1; AI326478; Igh6; Igh-6; Ighm; Igh-M; Igm; immunoglobulin heavy constant mu; MU; muH; VH
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国