产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
TCR V beta 5.1/5.2 Monoclonal Antibody (MR9-4), FITC, eBioscience™
目录 :
11-5796-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
异硫氰酸荧光素
克隆名称 :
MR9-4
反应物种 :
小鼠
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 12
出版应用/物种/样本/稀释 | 参考文献 |
---|---|
| |
del Rio M, Rodriguez Barbosa J, Kremmer E, Forster R. CD103- and CD103+ bronchial lymph node dendritic cells are specialized in presenting and cross-presenting innocuous antigen to CD4+ and CD8+ T cells. J Immunol. 2007;178:6861-6 pubmed
|
产品信息
产品类型 :
抗体
产品名称 :
TCR V beta 5.1/5.2 Monoclonal Antibody (MR9-4), FITC, eBioscience™
目录# :
11-5796-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.25 µg/test
物种 :
小鼠
克隆 :
MR9-4
抗体亚型 :
IgG1, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors. Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome. Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The autoantibodies block TH1-mediated inflammatory autodestructive reactions and are believed to be a method by which the immune system compensates for disease. Most human T cells express the TCR alpha-beta and either CD4 or CD8 molecule (single positive, SP). A small number of T cells lack both CD4 and CD8 (double negative, DN). Increased percentages of alpha-beta DN T cells have been identified in some autoimmune and immunodeficiency disorders. Gamma-delta T cells are primarily found within the epithelium. They show less TCR diversity and recognize antigens differently than alpha-beta T cells. Subsets of gamma-delta T cells have shown antitumor and immunoregulatory activity.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.25 µg/test
别名 :
TCR V beta5.1;TCR V beta5.2;TCRV乙5.1;TCRV乙5.2;TCRV beta5.1;TCRV beta5.2;Vb5.1;Vb5.2;Vbeta5.1;Vbeta5.2
更多信息或购买 :
公司信息
赛默飞世尔
微博分享
关注我们的微博
- 来邦网
- 英文来邦
相关产品
产品浏览
- HELIOS Monoclonal Antibody (22F6), FITC, eBioscience™ | 11-9883-80
- HELIOS Monoclonal Antibody (22F6), FITC, eBioscience™ | 11-9883-82
- Ly-6D Monoclonal Antibody (49-H4), PE, eBioscience™ | 12-5974-80
- c-Rel Monoclonal Antibody (1RELAH5), PE, eBioscience™ | 12-6111-80
- TIGIT Monoclonal Antibody (GIGD7), PE, eBioscience™ | 12-9501-80
问题和意见