| 出版应用/物种/样本/稀释 | 参考文献 |
|---|
| Zhu L, Xie X, Zhang L, Wang H, Jie Z, Zhou X, et al. TBK-binding protein 1 regulates IL-15-induced autophagy and NKT cell survival. Nat Commun. 2018;9:2812 pubmed 出版商 |
| Schedel M, Jia Y, Michel S, Takeda K, Domenico J, Joetham A, et al. 1,25D3 prevents CD8(+)Tc2 skewing and asthma development through VDR binding changes to the Cyp11a1 promoter. Nat Commun. 2016;7:10213 pubmed 出版商 |
| Sagoo P, Garcia Z, Breart B, Lemaître F, Michonneau D, Albert M, et al. In vivo imaging of inflammasome activation reveals a subcapsular macrophage burst response that mobilizes innate and adaptive immunity. Nat Med. 2016;22:64-71 pubmed 出版商 |
| Traka M, Podojil J, McCarthy D, Miller S, Popko B. Oligodendrocyte death results in immune-mediated CNS demyelination. Nat Neurosci. 2016;19:65-74 pubmed 出版商 |
| Joly A, Deepti A, Seignez A, Goloudina A, Hebrard S, Schmitt E, et al. The HSP90 inhibitor, 17AAG, protects the intestinal stem cell niche and inhibits graft versus host disease development. Oncogene. 2016;35:2842-51 pubmed 出版商 |
| Tousif S, Singh Y, Prasad D, Sharma P, Van Kaer L, Das G. T cells from Programmed Death-1 deficient mice respond poorly to Mycobacterium tuberculosis infection. PLoS ONE. 2011;6:e19864 pubmed 出版商 |
| Werner J, Busl E, Farkas S, Schlitt H, Geissler E, Hornung M. DX5+NKT cells display phenotypical and functional differences between spleen and liver as well as NK1.1-Balb/c and NK1.1+ C57Bl/6 mice. BMC Immunol. 2011;12:26 pubmed 出版商 |
| Jacobs C, Duewell P, Heckelsmiller K, Wei J, Bauernfeind F, Ellermeier J, et al. An ISCOM vaccine combined with a TLR9 agonist breaks immune evasion mediated by regulatory T cells in an orthotopic model of pancreatic carcinoma. Int J Cancer. 2011;128:897-907 pubmed 出版商 |
| Kim K, Ryu J, Ko J, Kim J, Kim H, Lee H, et al. FUT1 deficiency elicits immune dysregulation and corneal opacity in steady state and under stress. Cell Death Dis. 2020;11:285 pubmed 出版商 |
| Liu Z, Wen J, Wu C, Hu C, Wang J, Bao Q, et al. MicroRNA-200a induces immunosuppression by promoting PTEN-mediated PD-L1 upregulation in osteosarcoma. Aging (Albany NY). 2020;12:1213-1236 pubmed 出版商 |
| Klepsch V, Pommermayr M, Humer D, Brigo N, Hermann Kleiter N, Baier G. Targeting the orphan nuclear receptor NR2F6 in T cells primes tumors for immune checkpoint therapy. Cell Commun Signal. 2020;18:8 pubmed 出版商 |
| Chang L, Wang L, Ling N, Peng H, Chen M. Increase in liver γδ T cells with concurrent augmentation of IFN-β production during the early stages of a mouse model of acute experimental hepatitis B virus infection. Exp Ther Med. 2020;19:67-78 pubmed 出版商 |
| Shi L, Wang J, Ding N, Zhang Y, Zhu Y, Dong S, et al. Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy. Nat Commun. 2019;10:5421 pubmed 出版商 |
| Xu J, Pei S, Wang Y, Liu J, Qian Y, Huang M, et al. Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells. Front Immunol. 2019;10:1980 pubmed 出版商 |
| Fu Z, Ye J, Dean J, Bostick J, Weinberg S, Xiong L, et al. Requirement of Mitochondrial Transcription Factor A in Tissue-Resident Regulatory T Cell Maintenance and Function. Cell Rep. 2019;28:159-171.e4 pubmed 出版商 |
| Pyaram K, Kumar A, Kim Y, Noel S, Reddy S, Rabb H, et al. Keap1-Nrf2 System Plays an Important Role in Invariant Natural Killer T Cell Development and Homeostasis. Cell Rep. 2019;27:699-707.e4 pubmed 出版商 |
| Lee H, Kim K, Ryu J, Jeong H, Lee S, Kim M. Bilateral Effect of the Unilateral Corneal Nerve Cut on Both Ocular Surface and Lacrimal Gland. Invest Ophthalmol Vis Sci. 2019;60:430-441 pubmed 出版商 |
| Scheer S, Ackloo S, Medina T, Schapira M, Li F, Ward J, et al. A chemical biology toolbox to study protein methyltransferases and epigenetic signaling. Nat Commun. 2019;10:19 pubmed 出版商 |
| Soriano Romaní L, Contreras Ruiz L, López García A, Diebold Y, Masli S. Topical Application of TGF-β-Activating Peptide, KRFK, Prevents Inflammatory Manifestations in the TSP-1-Deficient Mouse Model of Chronic Ocular Inflammation. Int J Mol Sci. 2018;20: pubmed 出版商 |
| Liu Z, Ge Y, Wang H, Ma C, Feist M, Ju S, et al. Modifying the cancer-immune set point using vaccinia virus expressing re-designed interleukin-2. Nat Commun. 2018;9:4682 pubmed 出版商 |
| Tosello Boari J, Araujo Furlan C, Fiocca Vernengo F, Rodríguez C, Ramello M, Amezcua Vesely M, et al. IL-17RA-Signaling Modulates CD8+ T Cell Survival and Exhaustion During Trypanosoma cruzi Infection. Front Immunol. 2018;9:2347 pubmed 出版商 |
| Chandra S, Gray J, Kiosses W, Khurana A, Hitomi K, Crosby C, et al. Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae. Nat Commun. 2018;9:4279 pubmed 出版商 |
| Hirota K, Hashimoto M, Ito Y, Matsuura M, Ito H, Tanaka M, et al. Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis. Immunity. 2018;48:1220-1232.e5 pubmed 出版商 |
| Pang P, Zheng K, Wu S, Xü H, Deng L, Shi Y, et al. Baicalin Downregulates RLRs Signaling Pathway to Control Influenza A Virus Infection and Improve the Prognosis. Evid Based Complement Alternat Med. 2018;2018:4923062 pubmed 出版商 |
| Li J, Lee Y, Li Y, Jiang Y, Lu H, Zang W, et al. Co-inhibitory Molecule B7 Superfamily Member 1 Expressed by Tumor-Infiltrating Myeloid Cells Induces Dysfunction of Anti-tumor CD8+ T Cells. Immunity. 2018;48:773-786.e5 pubmed 出版商 |
| Sun C, Lan P, Han Q, Huang M, Zhang Z, Xu G, et al. Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion. Nat Commun. 2018;9:1241 pubmed 出版商 |
| Moreno Fernandez M, Giles D, Stankiewicz T, Sheridan R, Karns R, Cappelletti M, et al. Peroxisomal β-oxidation regulates whole body metabolism, inflammatory vigor, and pathogenesis of nonalcoholic fatty liver disease. JCI Insight. 2018;3: pubmed 出版商 |
| Kim D, Park H, Lim S, Koo J, Lee H, Choi J, et al. Regulation of chitinase-3-like-1 in T cell elicits Th1 and cytotoxic responses to inhibit lung metastasis. Nat Commun. 2018;9:503 pubmed 出版商 |
| Lu Y, Kim N, Jiang Y, Zhang H, Zheng D, Zhu F, et al. Cambogin suppresses dextran sulphate sodium-induced colitis by enhancing Treg cell stability and function. Br J Pharmacol. 2018;175:1085-1099 pubmed 出版商 |
| Gaya M, Barral P, Burbage M, Aggarwal S, Montaner B, Warren Navia A, et al. Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells. Cell. 2018;172:517-533.e20 pubmed 出版商 |
| Deng R, Hurtz C, Song Q, Yue C, Xiao G, Yu H, et al. Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease. Nat Commun. 2017;8:978 pubmed 出版商 |
| Chu F, Hu Y, Zhou Y, Guo M, Lu J, Zheng W, et al. MicroRNA-126 deficiency enhanced the activation and function of CD4+ T cells by elevating IRS-1 pathway. Clin Exp Immunol. 2017;: pubmed 出版商 |
| Wang H, Li J, Han Q, Yang F, Xiao Y, Xiao M, et al. IL-12 Influence mTOR to Modulate CD8+ T Cells Differentiation through T-bet and Eomesodermin in Response to Invasive Pulmonary Aspergillosis. Int J Med Sci. 2017;14:977-983 pubmed 出版商 |
| Robert R, Ang C, Sun G, Juglair L, Lim E, Mason L, et al. Essential role for CCR6 in certain inflammatory diseases demonstrated using specific antagonist and knockin mice. JCI Insight. 2017;2: pubmed 出版商 |
| Ma J, Teng X, Wang X, Fan X, Wu Y, Tian M, et al. A Multistage Subunit Vaccine Effectively Protects Mice Against Primary Progressive Tuberculosis, Latency and Reactivation. EBioMedicine. 2017;22:143-154 pubmed 出版商 |
| Yu Q, Wang X, Fan X. A New Adjuvant MTOM Mediates Mycobacterium tuberculosis Subunit Vaccine to Enhance Th1-Type T Cell Immune Responses and IL-2+ T Cells. Front Immunol. 2017;8:585 pubmed 出版商 |
| Friedrich C, Mamareli P, Thiemann S, Kruse F, Wang Z, Holzmann B, et al. MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium. PLoS Pathog. 2017;13:e1006357 pubmed 出版商 |
| Miao T, Symonds A, Singh R, Symonds J, Ogbe A, Omodho B, et al. Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation. J Exp Med. 2017;214:1787-1808 pubmed 出版商 |
| Cui N, Wang H, Su L, Zhang J, Long Y, Liu D. Role of Triggering Receptor Expressed on Myeloid Cell-1 Expression in Mammalian Target of Rapamycin Modulation of CD8+ T-cell Differentiation during the Immune Response to Invasive Pulmonary Aspergillosis. Chin Med J (Engl). 2017;130:1211-1217 pubmed 出版商 |
| Li Y, Liu X, Duan W, Tian H, Zhu G, He H, et al. Batf3-dependent CD8?+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages. EBioMedicine. 2017;18:188-198 pubmed 出版商 |
| Allen E, Jabouille A, Rivera L, Lodewijckx I, Missiaen R, Steri V, et al. Combined antiangiogenic and anti-PD-L1 therapy stimulates tumor immunity through HEV formation. Sci Transl Med. 2017;9: pubmed 出版商 |
| Jie Z, Liang Y, Yi P, Tang H, Soong L, Cong Y, et al. Retinoic Acid Regulates Immune Responses by Promoting IL-22 and Modulating S100 Proteins in Viral Hepatitis. J Immunol. 2017;198:3448-3460 pubmed 出版商 |
| Klein J, Moses K, Zelinskyy G, Sody S, Buer J, Lang S, et al. Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth. Nat Commun. 2017;8:14600 pubmed 出版商 |
| Cho J, Lee H, Ko H, Yoon B, Choe J, Kim K, et al. The TLR7 agonist imiquimod induces anti-cancer effects via autophagic cell death and enhances anti-tumoral and systemic immunity during radiotherapy for melanoma. Oncotarget. 2017;8:24932-24948 pubmed 出版商 |
| Zhang H, Qi Y, Yuan Y, Cai L, Xu H, Zhang L, et al. Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation. Sci Rep. 2017;7:41887 pubmed 出版商 |
| Berlato C, Khan M, Schioppa T, Thompson R, Maniati E, Montfort A, et al. A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer. J Clin Invest. 2017;127:801-813 pubmed 出版商 |
| Cruz L, Hashemifar S, Wu C, Cho S, Nguyen D, Lin L, et al. Excessive expression of miR-27 impairs Treg-mediated immunological tolerance. J Clin Invest. 2017;127:530-542 pubmed 出版商 |
| Aguilera T, Rafat M, Castellini L, Shehade H, Kariolis M, Hui A, et al. Reprogramming the immunological microenvironment through radiation and targeting Axl. Nat Commun. 2016;7:13898 pubmed 出版商 |
| Pangrazzi L, Meryk A, Naismith E, Koziel R, Lair J, Krismer M, et al. "Inflamm-aging" influences immune cell survival factors in human bone marrow. Eur J Immunol. 2017;47:481-492 pubmed 出版商 |
| Zhou Y, Weng X, Dou R, Tan X, Zhang T, Fang J, et al. Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice. Acta Pharmacol Sin. 2017;38:201-210 pubmed 出版商 |
| Chudnovskiy A, Mortha A, Kana V, Kennard A, Ramírez J, Rahman A, et al. Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome. Cell. 2016;167:444-456.e14 pubmed 出版商 |
| Gerriets V, Kishton R, Johnson M, Cohen S, Siska P, Nichols A, et al. Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression. Nat Immunol. 2016;17:1459-1466 pubmed 出版商 |
| Yang M, Chen S, Du J, He J, Wang Y, Li Z, et al. NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation. Nat Commun. 2016;7:12730 pubmed 出版商 |
| Clever D, Roychoudhuri R, Constantinides M, Askenase M, Sukumar M, Klebanoff C, et al. Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche. Cell. 2016;166:1117-1131.e14 pubmed 出版商 |
| Shi L, Fu T, Guan B, Chen J, Blando J, Allison J, et al. Interdependent IL-7 and IFN-? signalling in T-cell controls tumour eradication by combined ?-CTLA-4+?-PD-1 therapy. Nat Commun. 2016;7:12335 pubmed 出版商 |
| Haddad C, Bhattacharya P, Alharshawi K, Marinelarena A, Kumar P, El Sayed O, et al. Age-dependent divergent effects of OX40L treatment on the development of diabetes in NOD mice. Autoimmunity. 2016;49:298-311 pubmed 出版商 |
| Patel M, Kim J, Theodros D, Tam A, Velarde E, Kochel C, et al. Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma. J Immunother Cancer. 2016;4:28 pubmed 出版商 |
| Collins S, Chan Li Y, Oh M, Vigeland C, Limjunyawong N, Mitzner W, et al. Vaccinia vaccine-based immunotherapy arrests and reverses established pulmonary fibrosis. JCI Insight. 2016;1:e83116 pubmed |
| Tian Y, Kuo C, Akbari O, Ou J. Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission. Immunity. 2016;44:1204-14 pubmed 出版商 |
| Qi X, Gurung P, Malireddi R, Karmaus P, Sharma D, Vogel P, et al. Critical role of caspase-8-mediated IL-1 signaling in promoting Th2 responses during asthma pathogenesis. Mucosal Immunol. 2017;10:128-138 pubmed 出版商 |
| Martin B, Wang C, Zhang C, Kang Z, Gulen M, Zepp J, et al. T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis. Nat Immunol. 2016;17:583-92 pubmed 出版商 |
| Tosiek M, Fiette L, El Daker S, Eberl G, Freitas A. IL-15-dependent balance between Foxp3 and RORγt expression impacts inflammatory bowel disease. Nat Commun. 2016;7:10888 pubmed 出版商 |
| Watanabe N, Kaminuma O, Kitamura N, Hiroi T. Induced Treg Cells Augment the Th17-Mediated Intestinal Inflammatory Response in a CTLA4-Dependent Manner. PLoS ONE. 2016;11:e0150244 pubmed 出版商 |
| Yang L, Cai C, Feng Q, Shi Y, Zuo Q, Yang H, et al. Protective efficacy of the chimeric Staphylococcus aureus vaccine candidate IC in sepsis and pneumonia models. Sci Rep. 2016;6:20929 pubmed 出版商 |
| Singh S, Vedi S, Samrat S, Li W, Kumar R, Agrawal B. Heterologous Immunity between Adenoviruses and Hepatitis C Virus: A New Paradigm in HCV Immunity and Vaccines. PLoS ONE. 2016;11:e0146404 pubmed 出版商 |
| He L, Zhang Y, Ma G, Tan P, Li Z, Zang S, et al. Near-infrared photoactivatable control of Ca(2+) signaling and optogenetic immunomodulation. elife. 2015;4: pubmed 出版商 |
| Shao L, Zhou H, Zhang H, Qin L, Hwa J, Yun Z, et al. SENP1-mediated NEMO deSUMOylation in adipocytes limits inflammatory responses and type-1 diabetes progression. Nat Commun. 2015;6:8917 pubmed 出版商 |
| Wu J, Saleh M, Kirabo A, Itani H, Montaniel K, Xiao L, et al. Immune activation caused by vascular oxidation promotes fibrosis and hypertension. J Clin Invest. 2016;126:50-67 pubmed 出版商 |
| Suzuki Y, Maazi H, Sankaranarayanan I, Lam J, Khoo B, Soroosh P, et al. Lack of autophagy induces steroid-resistant airway inflammation. J Allergy Clin Immunol. 2016;137:1382-1389.e9 pubmed 出版商 |
| Singh Y, Garden O, Lang F, Cobb B. MicroRNA-15b/16 Enhances the Induction of Regulatory T Cells by Regulating the Expression of Rictor and mTOR. J Immunol. 2015;195:5667-77 pubmed 出版商 |
| Kawahara M, Takaku H. A tumor lysate is an effective vaccine antigen for the stimulation of CD4(+) T-cell function and subsequent induction of antitumor immunity mediated by CD8(+) T cells. Cancer Biol Ther. 2015;16:1616-25 pubmed 出版商 |
| Wang X, Huang Z, Chen Y, Lu X, Zhu P, Wen K, et al. A Multiple Antigenic Peptide Mimicking Peptidoglycan Induced T Cell Responses to Protect Mice from Systemic Infection with Staphylococcus aureus. PLoS ONE. 2015;10:e0136888 pubmed 出版商 |
| Yang B, Hagemann S, Mamareli P, Lauer U, Hoffmann U, Beckstette M, et al. Foxp3(+) T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation. Mucosal Immunol. 2016;9:444-57 pubmed 出版商 |
| Ampem G, Azegrouz H, Bacsadi Ã, Balogh L, Schmidt S, Thuróczy J, et al. Adipose tissue macrophages in non-rodent mammals: a comparative study. Cell Tissue Res. 2016;363:461-78 pubmed 出版商 |
| Vogel A, Brown D. Single-Dose CpG Immunization Protects Against a Heterosubtypic Challenge and Generates Antigen-Specific Memory T Cells. Front Immunol. 2015;6:327 pubmed 出版商 |
| Rose A, Hoffmann F, Hara J, Urschitz J, Moisyadi S, Hoffmann P, et al. Adjuvants may reduce in vivo transfection levels for DNA vaccination in mice leading to reduced antigen-specific CD8+ T cell responses. Hum Vaccin Immunother. 2015;11:2305-11 pubmed 出版商 |
| Li X, Xu J, Lv Z, Wang J, Sun S, Zhu W, et al. Inadequate activation of the HBsAg-specific Th cells by APCs leads to hyporesponsiveness to HBsAg vaccine in B10.S mice. Hum Vaccin Immunother. 2015;11:1735-43 pubmed 出版商 |
| Reis B, Lee K, Fanok M, Mascaraque C, Amoury M, Cohn L, et al. Leptin receptor signaling in T cells is required for Th17 differentiation. J Immunol. 2015;194:5253-60 pubmed 出版商 |
| Teng X, Tian M, Li J, Tan S, Yuan X, Yu Q, et al. Immunogenicity and protective efficacy of DMT liposome-adjuvanted tuberculosis subunit CTT3H vaccine. Hum Vaccin Immunother. 2015;11:1456-64 pubmed 出版商 |
| Annemann M, Wang Z, Plaza Sirvent C, Glauben R, Schuster M, Ewald Sander F, et al. IκBNS regulates murine Th17 differentiation during gut inflammation and infection. J Immunol. 2015;194:2888-98 pubmed 出版商 |
| Siggs O, Miosge L, Daley S, Asquith K, Foster P, Liston A, et al. Quantitative reduction of the TCR adapter protein SLP-76 unbalances immunity and immune regulation. J Immunol. 2015;194:2587-95 pubmed 出版商 |
| Stack G, Jones E, Marsden M, Stacey M, Snelgrove R, Lacaze P, et al. CD200 receptor restriction of myeloid cell responses antagonizes antiviral immunity and facilitates cytomegalovirus persistence within mucosal tissue. PLoS Pathog. 2015;11:e1004641 pubmed 出版商 |
| Santori F, Huang P, van de Pavert S, Douglass E, Leaver D, Haubrich B, et al. Identification of natural RORγ ligands that regulate the development of lymphoid cells. Cell Metab. 2015;21:286-298 pubmed 出版商 |
| Ohshio Y, Teramoto K, Hanaoka J, Tezuka N, Itoh Y, Asai T, et al. Cancer-associated fibroblast-targeted strategy enhances antitumor immune responses in dendritic cell-based vaccine. Cancer Sci. 2015;106:134-42 pubmed 出版商 |
| Niebling J, E Rünker A, Schallenberg S, Kretschmer K, Kempermann G. Myelin-specific T helper 17 cells promote adult hippocampal neurogenesis through indirect mechanisms. F1000Res. 2014;3:169 pubmed 出版商 |
| Simpson L, Patel S, Bhakta N, Choy D, Brightbill H, Ren X, et al. A microRNA upregulated in asthma airway T cells promotes TH2 cytokine production. Nat Immunol. 2014;15:1162-70 pubmed 出版商 |
| Hou H, Liu W, Wu S, Lu Y, Peng J, Zhu Y, et al. Tim-3 negatively mediates natural killer cell function in LPS-induced endotoxic shock. PLoS ONE. 2014;9:e110585 pubmed 出版商 |
| Burger M, Leung K, Bennett M, Winoto A. T cell-specific inhibition of multiple apoptotic pathways blocks negative selection and causes autoimmunity. elife. 2014;3: pubmed 出版商 |
| Fujiwara H, Maeda Y, Kobayashi K, Nishimori H, Matsuoka K, Fujii N, et al. Programmed death-1 pathway in host tissues ameliorates Th17/Th1-mediated experimental chronic graft-versus-host disease. J Immunol. 2014;193:2565-73 pubmed 出版商 |
| Dang S, Xu H, Xu C, Cai W, Li Q, Cheng Y, et al. Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis. Autophagy. 2014;10:1301-15 pubmed 出版商 |
| Montufar Solis D, Vigneswaran N, Nakra N, Schaefer J, Klein J. Hematopoietic not systemic impairment of Roquin expression accounts for intestinal inflammation in Roquin-deficient mice. Sci Rep. 2014;4:4920 pubmed 出版商 |
| Akitsu A, Kakuta S, Saijo S, Iwakura Y. Rag2-deficient IL-1 Receptor Antagonist-deficient Mice Are a Novel Colitis Model in Which Innate Lymphoid Cell-derived IL-17 Is Involved in the Pathogenesis. Exp Anim. 2014;63:235-46 pubmed |
| Mizukami J, Sato T, Camps M, Ji H, Rueckle T, Swinnen D, et al. ASK1 promotes the contact hypersensitivity response through IL-17 production. Sci Rep. 2014;4:4714 pubmed 出版商 |
| Ribeiro Gomes F, Roma E, Carneiro M, Doria N, Sacks D, Peters N. Site-dependent recruitment of inflammatory cells determines the effective dose of Leishmania major. Infect Immun. 2014;82:2713-27 pubmed 出版商 |
| Nagashima H, Okuyama Y, Asao A, Kawabe T, Yamaki S, Nakano H, et al. The adaptor TRAF5 limits the differentiation of inflammatory CD4(+) T cells by antagonizing signaling via the receptor for IL-6. Nat Immunol. 2014;15:449-56 pubmed 出版商 |
| Jie Z, Liang Y, Hou L, Dong C, Iwakura Y, Soong L, et al. Intrahepatic innate lymphoid cells secrete IL-17A and IL-17F that are crucial for T cell priming in viral infection. J Immunol. 2014;192:3289-300 pubmed 出版商 |
| Reba S, Li Q, Onwuzulike S, Ding X, Karim A, Hernandez Y, et al. TLR2 engagement on CD4(+) T cells enhances effector functions and protective responses to Mycobacterium tuberculosis. Eur J Immunol. 2014;44:1410-21 pubmed 出版商 |
| Molnarfi N, Schulze Topphoff U, Weber M, Patarroyo J, Prod homme T, Varrin Doyer M, et al. MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies. J Exp Med. 2013;210:2921-37 pubmed 出版商 |
| Wang S, Wu B, Xue J, Wang M, Chen R, Wang B. Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge. Hum Vaccin Immunother. 2014;10:461-8 pubmed 出版商 |
| Wong L, HATFIELD J, Brown M. Ikaros sets the potential for Th17 lineage gene expression through effects on chromatin state in early T cell development. J Biol Chem. 2013;288:35170-9 pubmed 出版商 |
| Wu B, Zou Q, Hu Y, Wang B. Interleukin-22 as a molecular adjuvant facilitates IL-17-producing CD8+ T cell responses against a HBV DNA vaccine in mice. Hum Vaccin Immunother. 2013;9:2133-41 pubmed 出版商 |
| Mandai Y, Takahashi D, Hase K, Obata Y, Furusawa Y, Ebisawa M, et al. Distinct Roles for CXCR6(+) and CXCR6(-) CD4(+) T Cells in the Pathogenesis of Chronic Colitis. PLoS ONE. 2013;8:e65488 pubmed 出版商 |
| Jia Y, Domenico J, Takeda K, Han J, Wang M, Armstrong M, et al. Steroidogenic enzyme Cyp11a1 regulates Type 2 CD8+ T cell skewing in allergic lung disease. Proc Natl Acad Sci U S A. 2013;110:8152-7 pubmed 出版商 |
| Chen Z, Kim S, Chamberlain N, Pickens S, Volin M, Volkov S, et al. The novel role of IL-7 ligation to IL-7 receptor in myeloid cells of rheumatoid arthritis and collagen-induced arthritis. J Immunol. 2013;190:5256-66 pubmed 出版商 |
| Yao C, Hirata T, Soontrapa K, Ma X, Takemori H, Narumiya S. Prostaglandin E? promotes Th1 differentiation via synergistic amplification of IL-12 signalling by cAMP and PI3-kinase. Nat Commun. 2013;4:1685 pubmed 出版商 |
| Jia Y, Takeda K, Han J, Joetham A, Marcus R, Lucas J, et al. Stepwise epigenetic and phenotypic alterations poise CD8+ T cells to mediate airway hyperresponsiveness and inflammation. J Immunol. 2013;190:4056-65 pubmed 出版商 |
| Helmersson S, Sundstedt A, Deronic A, Leanderson T, Ivars F. Amelioration of experimental autoimmune encephalomyelitis by the quinoline-3-carboxamide paquinimod: reduced priming of proinflammatory effector CD4(+) T cells. Am J Pathol. 2013;182:1671-80 pubmed 出版商 |
| Reis B, Rogoz A, Costa Pinto F, Taniuchi I, Mucida D. Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4? T cell immunity. Nat Immunol. 2013;14:271-80 pubmed 出版商 |
| Khan T, Wong E, Soni C, Rahman Z. Prolonged apoptotic cell accumulation in germinal centers of Mer-deficient mice causes elevated B cell and CD4+ Th cell responses leading to autoantibody production. J Immunol. 2013;190:1433-46 pubmed 出版商 |
| Sciumè G, Hirahara K, Takahashi H, Laurence A, Villarino A, Singleton K, et al. Distinct requirements for T-bet in gut innate lymphoid cells. J Exp Med. 2012;209:2331-8 pubmed 出版商 |
| Wan W, Lionakis M, Liu Q, Roffe E, Murphy P. Genetic deletion of chemokine receptor Ccr7 exacerbates atherogenesis in ApoE-deficient mice. Cardiovasc Res. 2013;97:580-8 pubmed 出版商 |
| Mishra A, Alves J, Krumbach K, Nigou J, Castro A, Geurtsen J, et al. Differential arabinan capping of lipoarabinomannan modulates innate immune responses and impacts T helper cell differentiation. J Biol Chem. 2012;287:44173-83 pubmed 出版商 |
| Gong Y, Wang Z, Liang Z, Duan H, Ouyang L, Yu Q, et al. Soluble MOG35-55/I-A(b) dimers ameliorate experimental autoimmune encephalomyelitis by reducing encephalitogenic T cells. PLoS ONE. 2012;7:e47435 pubmed 出版商 |
| Ito H, Yan X, Nagata N, Aritake K, Katsumata Y, Matsuhashi T, et al. PGD2-CRTH2 pathway promotes tubulointerstitial fibrosis. J Am Soc Nephrol. 2012;23:1797-809 pubmed 出版商 |
| Hayashi C, Papadopoulos G, Gudino C, Weinberg E, Barth K, Madrigal A, et al. Protective role for TLR4 signaling in atherosclerosis progression as revealed by infection with a common oral pathogen. J Immunol. 2012;189:3681-8 pubmed |
| Lemay C, Rintoul J, Kus A, Paterson J, Garcia V, Falls T, et al. Harnessing oncolytic virus-mediated antitumor immunity in an infected cell vaccine. Mol Ther. 2012;20:1791-9 pubmed 出版商 |
| Qu Z, Fu J, Ma H, Zhou J, Jin M, Mapara M, et al. PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease. Cell Biosci. 2012;2:23 pubmed 出版商 |
| Valdez P, Vithayathil P, Janelsins B, Shaffer A, Williamson P, Datta S. Prostaglandin E2 suppresses antifungal immunity by inhibiting interferon regulatory factor 4 function and interleukin-17 expression in T cells. Immunity. 2012;36:668-79 pubmed 出版商 |
| Seedhom M, Mathurin K, Kim S, Welsh R. Increased protection from vaccinia virus infection in mice genetically prone to lymphoproliferative disorders. J Virol. 2012;86:6010-22 pubmed 出版商 |
| Goicochea M, Zapata J, Bryant J, Davis H, Salvato M, Lukashevich I. Evaluation of Lassa virus vaccine immunogenicity in a CBA/J-ML29 mouse model. Vaccine. 2012;30:1445-52 pubmed 出版商 |
| Chatterjee S, Dwivedi V, Singh Y, Siddiqui I, Sharma P, Van Kaer L, et al. Early secreted antigen ESAT-6 of Mycobacterium tuberculosis promotes protective T helper 17 cell responses in a toll-like receptor-2-dependent manner. PLoS Pathog. 2011;7:e1002378 pubmed 出版商 |
| Nakahira M, Nakanishi K. Requirement of GATA-binding protein 3 for II13 gene expression in IL-18-stimulated Th1 cells. Int Immunol. 2011;23:761-72 pubmed 出版商 |
| Horie I, Abiru N, Sakamoto H, Iwakura Y, Nagayama Y. Induction of autoimmune thyroiditis by depletion of CD4+CD25+ regulatory T cells in thyroiditis-resistant IL-17, but not interferon-gamma receptor, knockout nonobese diabetic-H2h4 mice. Endocrinology. 2011;152:4448-54 pubmed 出版商 |
| Piehler D, Stenzel W, Grahnert A, Held J, Richter L, Kohler G, et al. Eosinophils contribute to IL-4 production and shape the T-helper cytokine profile and inflammatory response in pulmonary cryptococcosis. Am J Pathol. 2011;179:733-44 pubmed 出版商 |
| Do J, Visperas A, O Brien R, Min B. CD4 T cells play important roles in maintaining IL-17-producing ?? T-cell subsets in naive animals. Immunol Cell Biol. 2012;90:396-403 pubmed 出版商 |
| Xin L, Wanderley J, Wang Y, Vargas Inchaustegui D, Soong L. The magnitude of CD4(+) T-cell activation rather than TCR diversity determines the outcome of Leishmania infection in mice. Parasite Immunol. 2011;33:170-80 pubmed 出版商 |
| Lal G, Yin N, Xu J, Lin M, Schroppel S, Ding Y, et al. Distinct inflammatory signals have physiologically divergent effects on epigenetic regulation of Foxp3 expression and Treg function. Am J Transplant. 2011;11:203-14 pubmed 出版商 |
| Yabu M, Shime H, Hara H, Saito T, Matsumoto M, Seya T, et al. IL-23-dependent and -independent enhancement pathways of IL-17A production by lactic acid. Int Immunol. 2011;23:29-41 pubmed 出版商 |
| Wang S, Chang C, Yen M, Tu C, Chu C, Peng Y, et al. RNA interference-mediated silencing of Foxo3 in antigen-presenting cells as a strategy for the enhancement of DNA vaccine potency. Gene Ther. 2011;18:372-83 pubmed 出版商 |
| Yi J, Ingram J, Zajac A. IL-21 deficiency influences CD8 T cell quality and recall responses following an acute viral infection. J Immunol. 2010;185:4835-45 pubmed 出版商 |
| Eliçabe R, Cargnelutti E, Serer M, Stege P, Valdez S, Toscano M, et al. Lack of TNFR p55 results in heightened expression of IFN-? and IL-17 during the development of reactive arthritis. J Immunol. 2010;185:4485-95 pubmed 出版商 |
| Kitamura K, Farber J, Kelsall B. CCR6 marks regulatory T cells as a colon-tropic, IL-10-producing phenotype. J Immunol. 2010;185:3295-304 pubmed 出版商 |
| Sharabi A, Laronne Bar On A, Meshorer A, Haran Ghera N. Chemoimmunotherapy reduces the progression of multiple myeloma in a mouse model. Cancer Prev Res (Phila). 2010;3:1265-76 pubmed 出版商 |
| Tatum A, Watson A, Schell T. Direct presentation regulates the magnitude of the CD8+ T cell response to cell-associated antigen through prolonged T cell proliferation. J Immunol. 2010;185:2763-72 pubmed 出版商 |
| Nakamura R, Maeda N, Shibata K, Yamada H, Kase T, Yoshikai Y. Interleukin-15 is critical in the pathogenesis of influenza a virus-induced acute lung injury. J Virol. 2010;84:5574-82 pubmed 出版商 |
| Elftman M, Hunzeker J, Mellinger J, Bonneau R, Norbury C, Truckenmiller M. Stress-induced glucocorticoids at the earliest stages of herpes simplex virus-1 infection suppress subsequent antiviral immunity, implicating impaired dendritic cell function. J Immunol. 2010;184:1867-75 pubmed 出版商 |
| Do J, Fink P, Li L, Spolski R, Robinson J, Leonard W, et al. Cutting edge: spontaneous development of IL-17-producing gamma delta T cells in the thymus occurs via a TGF-beta 1-dependent mechanism. J Immunol. 2010;184:1675-9 pubmed 出版商 |
| Gulani J, Norbury C, Bonneau R, Beckwith C. The effect of Helicobacter hepaticus infection on immune responses specific to herpes simplex virus type 1 and characteristics of dendritic cells. Comp Med. 2009;59:534-44 pubmed |
| Hondowicz B, Batheja A, Metzgar M, Caton A, Erikson J. ICOS expression by effector T cells influences the ability of regulatory T cells to inhibit anti-chromatin B cell responses in recipient mice. J Autoimmun. 2010;34:460-8 pubmed 出版商 |
| Pierau M, Engelmann S, Reinhold D, Lapp T, Schraven B, Bommhardt U. Protein kinase B/Akt signals impair Th17 differentiation and support natural regulatory T cell function and induced regulatory T cell formation. J Immunol. 2009;183:6124-34 pubmed 出版商 |
| Horie I, Abiru N, Nagayama Y, Kuriya G, Saitoh O, Ichikawa T, et al. T helper type 17 immune response plays an indispensable role for development of iodine-induced autoimmune thyroiditis in nonobese diabetic-H2h4 mice. Endocrinology. 2009;150:5135-42 pubmed 出版商 |
| Vargas Inchaustegui D, Tai W, Xin L, Hogg A, Corry D, Soong L. Distinct roles for MyD88 and Toll-like receptor 2 during Leishmania braziliensis infection in mice. Infect Immun. 2009;77:2948-56 pubmed 出版商 |
| Ohnmacht C, Pullner A, King S, Drexler I, Meier S, Brocker T, et al. Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity. J Exp Med. 2009;206:549-59 pubmed 出版商 |
| Hadeiba H, Sato T, Habtezion A, Oderup C, Pan J, Butcher E. CCR9 expression defines tolerogenic plasmacytoid dendritic cells able to suppress acute graft-versus-host disease. Nat Immunol. 2008;9:1253-60 pubmed 出版商 |
| Ryan C, STAVELEY O CARROLL K, Schell T. Combined anti-CD40 conditioning and well-timed immunization prolongs CD8+ T cell accumulation and control of established brain tumors. J Immunother. 2008;31:906-20 pubmed 出版商 |
| Wesselkamper S, Eppert B, Motz G, Lau G, Hassett D, Borchers M. NKG2D is critical for NK cell activation in host defense against Pseudomonas aeruginosa respiratory infection. J Immunol. 2008;181:5481-9 pubmed |
| Ashcraft K, Hunzeker J, Bonneau R. Psychological stress impairs the local CD8+ T cell response to mucosal HSV-1 infection and allows for increased pathogenicity via a glucocorticoid receptor-mediated mechanism. Psychoneuroendocrinology. 2008;33:951-63 pubmed 出版商 |
| Ashcraft K, Bonneau R. Psychological stress exacerbates primary vaginal herpes simplex virus type 1 (HSV-1) infection by impairing both innate and adaptive immune responses. Brain Behav Immun. 2008;22:1231-40 pubmed 出版商 |
| Smith S, Ludwig M, Wohler J, Bullard D, Szalai A, Barnum S. Deletion of both ICAM-1 and C3 enhances severity of experimental autoimmune encephalomyelitis compared to C3-deficient mice. Neurosci Lett. 2008;442:158-60 pubmed 出版商 |
| Ciesielski M, Kozbor D, Castanaro C, Barone T, Fenstermaker R. Therapeutic effect of a T helper cell supported CTL response induced by a survivin peptide vaccine against murine cerebral glioma. Cancer Immunol Immunother. 2008;57:1827-35 pubmed 出版商 |
| Voehringer D, Liang H, Locksley R. Homeostasis and effector function of lymphopenia-induced "memory-like" T cells in constitutively T cell-depleted mice. J Immunol. 2008;180:4742-53 pubmed |
| Sridhar S, Reyes Sandoval A, Draper S, Moore A, Gilbert S, Gao G, et al. Single-dose protection against Plasmodium berghei by a simian adenovirus vector using a human cytomegalovirus promoter containing intron A. J Virol. 2008;82:3822-33 pubmed 出版商 |
| Ou R, Zhang M, Huang L, Flavell R, Koni P, Moskophidis D. Regulation of immune response and inflammatory reactions against viral infection by VCAM-1. J Virol. 2008;82:2952-65 pubmed 出版商 |
| Lacasse P, Denis J, Lapointe R, Leclerc D, Lamarre A. Novel plant virus-based vaccine induces protective cytotoxic T-lymphocyte-mediated antiviral immunity through dendritic cell maturation. J Virol. 2008;82:785-94 pubmed |
| Wanasen N, Xin L, Soong L. Pathogenic role of B cells and antibodies in murine Leishmania amazonensis infection. Int J Parasitol. 2008;38:417-29 pubmed |
| Morello C, Kelley L, Munks M, Hill A, Spector D. DNA immunization using highly conserved murine cytomegalovirus genes encoding homologs of human cytomegalovirus UL54 (DNA polymerase) and UL105 (helicase) elicits strong CD8 T-cell responses and is protective against systemic challenge. J Virol. 2007;81:7766-75 pubmed |
| Adams J, Webb M, Hu X, Staunton D, Barnum S. Disruption of the beta2-integrin CD11d (alphaDbeta2) gene fails to protect against experimental autoimmune encephalomyelitis. J Neuroimmunol. 2007;184:180-7 pubmed |
| Richards J, Chang X, Blaser B, Caligiuri M, Zheng P, Liu Y. Tumor growth impedes natural-killer-cell maturation in the bone marrow. Blood. 2006;108:246-52 pubmed |
| Veldhoen M, Hocking R, Atkins C, Locksley R, Stockinger B. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity. 2006;24:179-89 pubmed |
| Yoo J, Omori M, Gyarmati D, Zhou B, Aye T, Brewer A, et al. Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin. J Exp Med. 2005;202:541-9 pubmed |
