产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD115 (c-fms) Monoclonal Antibody (AFS98), PE, eBioscience™
目录 :
12-1152-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
PE
克隆名称 :
AFS98
反应物种 :
小鼠
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 156
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 1:100; 图 e7b
Jacome Galarza C, Percin G, Muller J, Mass E, Lazarov T, Eitler J, et al. Developmental origin, functional maintenance and genetic rescue of osteoclasts. Nature. 2019;568:541-545 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2a, 2c
Puchner A, Saferding V, Bonelli M, Mikami Y, Hofmann M, Brunner J, et al. Non-classical monocytes as mediators of tissue destruction in arthritis. Ann Rheum Dis. 2018;77:1490-1497 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s4a
Metghalchi S, Vandestienne M, Haddad Y, Esposito B, Dairou J, Tedgui A, et al. Indoleamine 2 3-dioxygenase knockout limits angiotensin II-induced aneurysm in low density lipoprotein receptor-deficient mice fed with high fat diet. PLoS ONE. 2018;13:e0193737 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 s5
Hara T, Nakaoka H, Hayashi T, Mimura K, Hoshino D, Inoue M, et al. Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes. Proc Natl Acad Sci U S A. 2017;114:E4416-E4424 pubmed 出版商
  • 流式细胞仪; 小鼠; 表 s1
Kraakman M, Lee M, Al Sharea A, Dragoljevic D, Barrett T, Montenont E, et al. Neutrophil-derived S100 calcium-binding proteins A8/A9 promote reticulated thrombocytosis and atherogenesis in diabetes. J Clin Invest. 2017;127:2133-2147 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:250
Thomas D, Clare S, Sowerby J, Pardo M, Juss J, Goulding D, et al. Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity. J Exp Med. 2017;214:1111-1128 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 s5
Scott C, Zheng F, De Baetselier P, Martens L, Saeys Y, De Prijck S, et al. Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells. Nat Commun. 2016;7:10321 pubmed 出版商
  • 流式细胞仪; 小鼠
Leiva M, Quintana J, Ligos J, Hidalgo A. Haematopoietic ESL-1 enables stem cell proliferation in the bone marrow by limiting TGFβ availability. Nat Commun. 2016;7:10222 pubmed 出版商
  • 流式细胞仪; 小鼠
Cole C, Verdoni A, Ketkar S, Leight E, Russler Germain D, Lamprecht T, et al. PML-RARA requires DNA methyltransferase 3A to initiate acute promyelocytic leukemia. J Clin Invest. 2016;126:85-98 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 1c
Merches K, Khairnar V, Knuschke T, Shaabani N, Honke N, Duhan V, et al. Virus-Induced Type I Interferon Deteriorates Control of Systemic Pseudomonas Aeruginosa Infection. Cell Physiol Biochem. 2015;36:2379-92 pubmed 出版商
  • 流式细胞仪; 小鼠
Weber B, Schuster S, Zysset D, Rihs S, Dickgreber N, Schürch C, et al. TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance. PLoS Pathog. 2014;10:e1003900 pubmed 出版商
  • 流式细胞仪; 小鼠; 2 ug/ml; 图 s10
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Zhu M, Van Dyke T, Gyurko R. Resolvin E1 regulates osteoclast fusion via DC-STAMP and NFATc1. FASEB J. 2013;27:3344-53 pubmed 出版商
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Rose S, Misharin A, Perlman H. A novel Ly6C/Ly6G-based strategy to analyze the mouse splenic myeloid compartment. Cytometry A. 2012;81:343-50 pubmed 出版商
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Courtial N, Smink J, Kuvardina O, Leutz A, Gothert J, Lausen J. Tal1 regulates osteoclast differentiation through suppression of the master regulator of cell fusion DC-STAMP. FASEB J. 2012;26:523-32 pubmed 出版商
Youn J, Collazo M, Shalova I, Biswas S, Gabrilovich D. Characterization of the nature of granulocytic myeloid-derived suppressor cells in tumor-bearing mice. J Leukoc Biol. 2012;91:167-81 pubmed 出版商
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Cook A, Turner A, Braine E, Pobjoy J, Lenzo J, Hamilton J. Regulation of systemic and local myeloid cell subpopulations by bone marrow cell-derived granulocyte-macrophage colony-stimulating factor in experimental inflammatory arthritis. Arthritis Rheum. 2011;63:2340-51 pubmed 出版商
Lenzo J, Turner A, Cook A, Vlahos R, Anderson G, Reynolds E, et al. Control of macrophage lineage populations by CSF-1 receptor and GM-CSF in homeostasis and inflammation. Immunol Cell Biol. 2012;90:429-40 pubmed 出版商
Yan S, Wang L, Liu N, Wang Y, Chu Y. Critical role of interleukin-17/interleukin-17 receptor axis in mediating Con A-induced hepatitis. Immunol Cell Biol. 2012;90:421-8 pubmed 出版商
Qian B, Li J, Zhang H, Kitamura T, Zhang J, Campion L, et al. CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis. Nature. 2011;475:222-5 pubmed 出版商
Diao J, Zhao J, Winter E, Cattral M. Tumors suppress in situ proliferation of cytotoxic T cells by promoting differentiation of Gr-1(+) conventional dendritic cells through IL-6. J Immunol. 2011;186:5058-67 pubmed 出版商
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Welch J, Yuan W, Ley T. PML-RARA can increase hematopoietic self-renewal without causing a myeloproliferative disease in mice. J Clin Invest. 2011;121:1636-45 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
CD115 (c-fms) Monoclonal Antibody (AFS98), PE, eBioscience™
目录# :
12-1152-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.06 µg/test
物种 :
小鼠
克隆 :
AFS98
抗体亚型 :
IgG2a, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
CSF1R (colony stimulating factor 1 receptor) is a cytokine that controls the production, differentiation, and function of macrophages. CSF1R mediates most if not all of the biological effects of CSF1. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. CSF1R is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in the gene encoding CSF1R have been associated with a predisposition to myeloid malignancy.Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and plays an important role in innate immunity and in inflammatory processes. The first intron of the CSF1R gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Mutations in the CSF1R gene have been associated with a predisposition to myeloid malignancy.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.06 µg/test
别名 :
AI323359; CD115; CD115 antigen; C-FMS; colony stimulating factor 1 receptor; colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog; CSF-1 receptor; CSF1R; CSF-1R; CSF-1-R; Csfmr; CSFR; EC 2.7.10.1; FIM2; Fim-2; FMS; fms proto-oncogene; HDLS; kinase CSFR; macrophage colony stimulating factor I receptor; macrophage colony-stimulating factor 1 receptor; McDonough feline sarcoma viral (v-fms) oncogene homolog; M-CSFR; M-CSF-R; mrfms; OTTHUMP00000224093; protein-tyrosine kinase; proto-oncogene c-Fms; proto-oncogene fms
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国