| 出版应用/物种/样本/稀释 | 参考文献 |
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| Blagih J, Zani F, Chakravarty P, Hennequart M, Pilley S, Hobor S, et al. Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses. Cell Rep. 2020;30:481-496.e6 pubmed 出版商 |
| Lu Y, Kim N, Jiang Y, Zhang H, Zheng D, Zhu F, et al. Cambogin suppresses dextran sulphate sodium-induced colitis by enhancing Treg cell stability and function. Br J Pharmacol. 2018;175:1085-1099 pubmed 出版商 |
| Zamarin D, Holmgaard R, Ricca J, Plitt T, Palese P, Sharma P, et al. Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity. Nat Commun. 2017;8:14340 pubmed 出版商 |
- 流式细胞仪; 人类; 1:200; 图 1
- 流式细胞仪; 小鼠; 1:200; 图 1
| Shi L, Fu T, Guan B, Chen J, Blando J, Allison J, et al. Interdependent IL-7 and IFN-? signalling in T-cell controls tumour eradication by combined ?-CTLA-4+?-PD-1 therapy. Nat Commun. 2016;7:12335 pubmed 出版商 |
| Li C, Li W, Xiao J, Jiao S, Teng F, Xue S, et al. ADAP and SKAP55 deficiency suppresses PD-1 expression in CD8+ cytotoxic T lymphocytes for enhanced anti-tumor immunotherapy. EMBO Mol Med. 2015;7:754-69 pubmed 出版商 |
| Kuwahara M, Suzuki J, Tofukuji S, Yamada T, Kanoh M, Matsumoto A, et al. The Menin-Bach2 axis is critical for regulating CD4 T-cell senescence and cytokine homeostasis. Nat Commun. 2014;5:3555 pubmed 出版商 |
| Kiesel J, Buchwald Z, Aurora R. Cross-presentation by osteoclasts induces FoxP3 in CD8+ T cells. J Immunol. 2009;182:5477-87 pubmed 出版商 |
| Gurusamy M, Tischner D, Shao J, Klatt S, Zukunft S, Bonnavion R, et al. G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators. Nat Commun. 2021;12:6798 pubmed 出版商 |
| Kalim K, Yang J, Modur V, Nguyen P, Li Y, Zheng Y, et al. Graded RhoA GTPase Expression in Treg Cells Distinguishes Tumor Immunity From Autoimmunity. Front Immunol. 2021;12:726393 pubmed 出版商 |
| Vick S, Kolupaev O, Perou C, Serody J. Anti-PD-1 Checkpoint Therapy Can Promote the Function and Survival of Regulatory T Cells. J Immunol. 2021;207:2598-2607 pubmed 出版商 |
| Lou Y, Wang J, Peng P, Wang S, Liu P, Xu L. Downregulated TNF-α Levels after Cryo-Thermal Therapy Drive Tregs Fragility to Promote Long-Term Antitumor Immunity. Int J Mol Sci. 2021;22: pubmed 出版商 |
| Ferrere G, Tidjani Alou M, Liu P, Goubet A, Fidelle M, Kepp O, et al. Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade. JCI Insight. 2021;6: pubmed 出版商 |
| Mendu S, Stremska M, Schappe M, Moser E, Krupa J, Rogers J, et al. Targeting the ion channel TRPM7 promotes the thymic development of regulatory T cells by promoting IL-2 signaling. Sci Signal. 2020;13: pubmed 出版商 |
| Drescher H, Schippers A, Rosenhain S, Gremse F, Bongiovanni L, Bruin A, et al. L-Selectin/CD62L is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men. Cells. 2020;9: pubmed 出版商 |
| Fenninger F, Han J, Stanwood S, Nohara L, Arora H, Choi K, et al. Mutation of an L-Type Calcium Channel Gene Leads to T Lymphocyte Dysfunction. Front Immunol. 2019;10:2473 pubmed 出版商 |
| Pontes Ferreira C, Cariste L, Ferri Moraschi B, Ferrarini Zanetti B, Won Han S, Araki Ribeiro D, et al. CXCR3 chemokine receptor guides Trypanosoma cruzi-specific T-cells triggered by DNA/adenovirus ASP2 vaccine to heart tissue after challenge. PLoS Negl Trop Dis. 2019;13:e0007597 pubmed 出版商 |
| Choi H, Deng J, Li S, Silk T, Dong L, Brea E, et al. Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer. Cell Rep. 2019;27:806-819.e5 pubmed 出版商 |
| Araujo Furlan C, Tosello Boari J, Rodríguez C, Canale F, Fiocca Vernengo F, Boccardo S, et al. Limited Foxp3+ Regulatory T Cells Response During Acute Trypanosoma cruzi Infection Is Required to Allow the Emergence of Robust Parasite-Specific CD8+ T Cell Immunity. Front Immunol. 2018;9:2555 pubmed 出版商 |
| Hirata Y, Furuhashi K, Ishii H, Li H, Pinho S, Ding L, et al. CD150high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine. Cell Stem Cell. 2018;22:445-453.e5 pubmed 出版商 |
| Ferreira C, Cariste L, Santos Virgílio F, Moraschi B, Monteiro C, Vieira Machado A, et al. LFA-1 Mediates Cytotoxicity and Tissue Migration of Specific CD8+ T Cells after Heterologous Prime-Boost Vaccination against Trypanosoma cruzi Infection. Front Immunol. 2017;8:1291 pubmed 出版商 |
| Itakura G, Ozaki M, Nagoshi N, Kawabata S, Nishiyama Y, Sugai K, et al. Low immunogenicity of mouse induced pluripotent stem cell-derived neural stem/progenitor cells. Sci Rep. 2017;7:12996 pubmed 出版商 |
| Schwartz C, Khan A, Floudas A, Saunders S, Hams E, Rodewald H, et al. ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control. J Exp Med. 2017;214:2507-2521 pubmed 出版商 |
| Peer S, Baier G, Gruber T. Cblb-deficient T cells are less susceptible to PD-L1-mediated inhibition. Oncotarget. 2017;8:41841-41853 pubmed 出版商 |
| Menendez C, Jinkins J, Carr D. Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency. J Immunol. 2016;197:1262-75 pubmed 出版商 |
| Ersching J, Basso A, Kalich V, Bortoluci K, Rodrigues M. A Human Trypanosome Suppresses CD8+ T Cell Priming by Dendritic Cells through the Induction of Immune Regulatory CD4+ Foxp3+ T Cells. PLoS Pathog. 2016;12:e1005698 pubmed 出版商 |
| Yuan C, Sun X, Zhu C, Liu S, Wu L, Chen H, et al. Amphiregulin activates regulatory T lymphocytes and suppresses CD8+ T cell-mediated anti-tumor response in hepatocellular carcinoma cells. Oncotarget. 2015;6:32138-53 pubmed 出版商 |
| Tähtinen S, Kaikkonen S, Merisalo Soikkeli M, Grönberg Vähä Koskela S, Kanerva A, Parviainen S, et al. Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors. PLoS ONE. 2015;10:e0131242 pubmed 出版商 |
| Tang L, Bai J, Chung C, Lomas Neira J, Chen Y, Huang X, et al. Active players in resolution of shock/sepsis induced indirect lung injury: immunomodulatory effects of Tregs and PD-1. J Leukoc Biol. 2014;96:809-20 pubmed 出版商 |
| Tang L, Bai J, Chung C, Lomas Neira J, Chen Y, Huang X, et al. Programmed cell death receptor ligand 1 modulates the regulatory T cells' capacity to repress shock/sepsis-induced indirect acute lung injury by recruiting phosphatase SRC homology region 2 domain-containing phosphatase 1. Shock. 2015;43:47-54 pubmed 出版商 |
| Kim E, Gasper D, Lee S, Plisch E, Svaren J, Suresh M. Bach2 regulates homeostasis of Foxp3+ regulatory T cells and protects against fatal lung disease in mice. J Immunol. 2014;192:985-95 pubmed 出版商 |
| Graham J, Da Costa A, Lund J. Regulatory T cells shape the resident memory T cell response to virus infection in the tissues. J Immunol. 2014;192:683-90 pubmed 出版商 |
| Schijf M, Kerperien J, Bastiaans J, Szklany K, Meerding J, Hofman G, et al. Alterations in regulatory T cells induced by specific oligosaccharides improve vaccine responsiveness in mice. PLoS ONE. 2013;8:e75148 pubmed 出版商 |
| Lee J, Jeon E, Kim N, Nam Y, Im K, Lim J, et al. The synergistic immunoregulatory effects of culture-expanded mesenchymal stromal cells and CD4(+)25(+)Foxp3+ regulatory T cells on skin allograft rejection. PLoS ONE. 2013;8:e70968 pubmed 出版商 |
| Huang H, Dawicki W, Lu M, Nayyar A, Zhang X, Gordon J. Regulatory dendritic cell expression of MHCII and IL-10 are jointly requisite for induction of tolerance in a murine model of OVA-asthma. Allergy. 2013;68:1126-35 pubmed 出版商 |
| Liu Y, Lan Q, Lu L, Chen M, Xia Z, Ma J, et al. Phenotypic and functional characteristic of a newly identified CD8+ Foxp3- CD103+ regulatory T cells. J Mol Cell Biol. 2014;6:81-92 pubmed 出版商 |
| Huang H, Ma Y, Dawicki W, Zhang X, Gordon J. Comparison of induced versus natural regulatory T cells of the same TCR specificity for induction of tolerance to an environmental antigen. J Immunol. 2013;191:1136-43 pubmed 出版商 |
| Rohlman D, Punj S, Pennington J, Bradford S, Kerkvliet N. Suppression of acute graft-versus-host response by TCDD is independent of the CTLA-4-IFN-?-IDO pathway. Toxicol Sci. 2013;135:81-90 pubmed 出版商 |
| Ehrentraut H, Clambey E, McNamee E, Brodsky K, Ehrentraut S, Poth J, et al. CD73+ regulatory T cells contribute to adenosine-mediated resolution of acute lung injury. FASEB J. 2013;27:2207-19 pubmed 出版商 |
| Mc Guire C, Wieghofer P, Elton L, Muylaert D, Prinz M, Beyaert R, et al. Paracaspase MALT1 deficiency protects mice from autoimmune-mediated demyelination. J Immunol. 2013;190:2896-903 pubmed 出版商 |
| Kron M, Metwali A, Vodanovic Jankovic S, Elliott D. Nematode asparaginyl-tRNA synthetase resolves intestinal inflammation in mice with T-cell transfer colitis. Clin Vaccine Immunol. 2013;20:276-81 pubmed 出版商 |
| Nakagomi D, Suzuki K, Hosokawa J, Kobayashi Y, Suto A, Takatori H, et al. Therapeutic potential of B and T lymphocyte attenuator expressed on CD8+ T cells for contact hypersensitivity. J Invest Dermatol. 2013;133:702-711 pubmed 出版商 |
| Getts D, Martin A, McCarthy D, Terry R, Hunter Z, Yap W, et al. Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis. Nat Biotechnol. 2012;30:1217-24 pubmed 出版商 |
| Park H, Kusnadi A, Lee E, Kim W, Cho B, Lee I, et al. Tumor-infiltrating regulatory T cells delineated by upregulation of PD-1 and inhibitory receptors. Cell Immunol. 2012;278:76-83 pubmed 出版商 |
| Gong Y, Wang Z, Liang Z, Duan H, Ouyang L, Yu Q, et al. Soluble MOG35-55/I-A(b) dimers ameliorate experimental autoimmune encephalomyelitis by reducing encephalitogenic T cells. PLoS ONE. 2012;7:e47435 pubmed 出版商 |
| de Andrade Pereira B, Fraefel C, Hilbe M, Ackermann M, Dresch C. Transcriptional targeting of DCs with lentiviral vectors induces antigen-specific tolerance in a mouse model of multiple sclerosis. Gene Ther. 2013;20:556-66 pubmed 出版商 |
| Guo X, Jie Y, Ren D, Zeng H, Zhang Y, He Y, et al. In vitro-expanded CD4(+)CD25(high)Foxp3(+) regulatory T cells controls corneal allograft rejection. Hum Immunol. 2012;73:1061-7 pubmed 出版商 |
| Weiss R, Hessenberger M, Kitzmüller S, Bach D, Weinberger E, Krautgartner W, et al. Transcutaneous vaccination via laser microporation. J Control Release. 2012;162:391-9 pubmed 出版商 |
| Altin J, Goodnow C, Cook M. IL-10+ CTLA-4+ Th2 inhibitory cells form in a Foxp3-independent, IL-2-dependent manner from Th2 effectors during chronic inflammation. J Immunol. 2012;188:5478-88 pubmed 出版商 |
| Gu P, Gao J, D Souza C, Kowalczyk A, Chou K, Zhang L. Trogocytosis of CD80 and CD86 by induced regulatory T cells. Cell Mol Immunol. 2012;9:136-46 pubmed 出版商 |
| Tenorio E, Fernandez J, Castellanos C, Olguín J, Saavedra R. CD4+ Foxp3+ regulatory T cells mediate Toxoplasma gondii-induced T-cell suppression through an IL-2-related mechanism but independently of IL-10. Eur J Immunol. 2011;41:3529-41 pubmed 出版商 |
| Kastenmuller W, Gasteiger G, Subramanian N, Sparwasser T, Busch D, Belkaid Y, et al. Regulatory T cells selectively control CD8+ T cell effector pool size via IL-2 restriction. J Immunol. 2011;187:3186-97 pubmed 出版商 |
| Zhao J, Zhao J, Fett C, Trandem K, Fleming E, Perlman S. IFN-γ- and IL-10-expressing virus epitope-specific Foxp3(+) T reg cells in the central nervous system during encephalomyelitis. J Exp Med. 2011;208:1571-7 pubmed 出版商 |
| Gaddis D, Michalek S, Katz J. TLR4 signaling via MyD88 and TRIF differentially shape the CD4+ T cell response to Porphyromonas gingivalis hemagglutinin B. J Immunol. 2011;186:5772-83 pubmed 出版商 |
| Liu C, Ye P, Yen B, Miao C. In vivo expansion of regulatory T cells with IL-2/IL-2 mAb complexes prevents anti-factor VIII immune responses in hemophilia A mice treated with factor VIII plasmid-mediated gene therapy. Mol Ther. 2011;19:1511-20 pubmed 出版商 |
| Lee H, Lee H, Kwon Y, Lee J, Kim J, Shin M, et al. Methyl gallate exhibits potent antitumor activities by inhibiting tumor infiltration of CD4+CD25+ regulatory T cells. J Immunol. 2010;185:6698-705 pubmed 出版商 |
| He C, Prevot N, Boitard C, Avner P, Rogner U. Inhibition of type 1 diabetes by upregulation of the circadian rhythm-related aryl hydrocarbon receptor nuclear translocator-like 2. Immunogenetics. 2010;62:585-92 pubmed 出版商 |
| Lages C, Lewkowich I, Sproles A, Wills Karp M, Chougnet C. Partial restoration of T-cell function in aged mice by in vitro blockade of the PD-1/?PD-L1 pathway. Aging Cell. 2010;9:785-98 pubmed 出版商 |
| Fulton R, Meyerholz D, Varga S. Foxp3+ CD4 regulatory T cells limit pulmonary immunopathology by modulating the CD8 T cell response during respiratory syncytial virus infection. J Immunol. 2010;185:2382-92 pubmed 出版商 |
| Sugita S, Horie S, Yamada Y, Mochizuki M. Inhibition of B-cell activation by retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2010;51:5783-8 pubmed 出版商 |
| Teng L, Liu L, Su Y, Yuan X, Li J, Fu Q, et al. Suppression of alloimmunity in mice by regulatory T cells converted with conditioned media. J Surg Res. 2011;171:797-806 pubmed 出版商 |
| Zaiss M, Sarter K, Hess A, Engelke K, Böhm C, Nimmerjahn F, et al. Increased bone density and resistance to ovariectomy-induced bone loss in FoxP3-transgenic mice based on impaired osteoclast differentiation. Arthritis Rheum. 2010;62:2328-38 pubmed 出版商 |
| Sugita S, Horie S, Yamada Y, Keino H, Usui Y, Takeuchi M, et al. Suppression of bystander T helper 1 cells by iris pigment epithelium-inducing regulatory T cells via negative costimulatory signals. Invest Ophthalmol Vis Sci. 2010;51:2529-36 pubmed 出版商 |
| Pierau M, Engelmann S, Reinhold D, Lapp T, Schraven B, Bommhardt U. Protein kinase B/Akt signals impair Th17 differentiation and support natural regulatory T cell function and induced regulatory T cell formation. J Immunol. 2009;183:6124-34 pubmed 出版商 |
| Blache C, Adriouch S, Calbo S, Drouot L, Dulauroy S, Arnoult C, et al. Cutting edge: CD4-independent development of functional FoxP3+ regulatory T cells. J Immunol. 2009;183:4182-6 pubmed 出版商 |
| Walsh K, Brady M, Finlay C, Boon L, Mills K. Infection with a helminth parasite attenuates autoimmunity through TGF-beta-mediated suppression of Th17 and Th1 responses. J Immunol. 2009;183:1577-86 pubmed 出版商 |
| Liu Z, Kim J, Falo L, You Z. Tumor regulatory T cells potently abrogate antitumor immunity. J Immunol. 2009;182:6160-7 pubmed 出版商 |
| Webster K, Walters S, Kohler R, Mrkvan T, Boyman O, Surh C, et al. In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression. J Exp Med. 2009;206:751-60 pubmed 出版商 |
| Lal G, Zhang N, van der Touw W, Ding Y, Ju W, Bottinger E, et al. Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation. J Immunol. 2009;182:259-73 pubmed |
| Saito K, Torii M, Ma N, Tsuchiya T, Wang L, Hori T, et al. Differential regulatory function of resting and preactivated allergen-specific CD4+ CD25+ regulatory T cells in Th2-type airway inflammation. J Immunol. 2008;181:6889-97 pubmed |
| Peng B, Ye P, Blazar B, Freeman G, Rawlings D, Ochs H, et al. Transient blockade of the inducible costimulator pathway generates long-term tolerance to factor VIII after nonviral gene transfer into hemophilia A mice. Blood. 2008;112:1662-72 pubmed 出版商 |
| Scumpia P, Delano M, Kelly Scumpia K, Weinstein J, Wynn J, Winfield R, et al. Treatment with GITR agonistic antibody corrects adaptive immune dysfunction in sepsis. Blood. 2007;110:3673-81 pubmed |
| Grigorian A, Lee S, Tian W, Chen I, Gao G, Mendelsohn R, et al. Control of T Cell-mediated autoimmunity by metabolite flux to N-glycan biosynthesis. J Biol Chem. 2007;282:20027-35 pubmed |
| Luo X, Tarbell K, Yang H, Pothoven K, Bailey S, Ding R, et al. Dendritic cells with TGF-beta1 differentiate naive CD4+CD25- T cells into islet-protective Foxp3+ regulatory T cells. Proc Natl Acad Sci U S A. 2007;104:2821-6 pubmed |
| Kapp J, Honjo K, Kapp L, Xu X, Cozier A, Bucy R. TCR transgenic CD8+ T cells activated in the presence of TGFbeta express FoxP3 and mediate linked suppression of primary immune responses and cardiac allograft rejection. Int Immunol. 2006;18:1549-62 pubmed |
| Zheng S, Meng L, Wang J, Watanabe M, Barr M, Cramer D, et al. Transfer of regulatory T cells generated ex vivo modifies graft rejection through induction of tolerogenic CD4+CD25+ cells in the recipient. Int Immunol. 2006;18:279-89 pubmed |
| Park H, Paik D, Jang E, Hong S, Youn J. Acquisition of anergic and suppressive activities in transforming growth factor-beta-costimulated CD4+CD25- T cells. Int Immunol. 2004;16:1203-13 pubmed |
