产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD154 (CD40 Ligand) Monoclonal Antibody (MR1), PE, eBioscience™
目录 :
12-1541-81
规格 :
50微克
价格 :
美国126
克隆性 :
单克隆
宿主 :
仓鼠
共轭标签 :
PE
克隆名称 :
MR1
反应物种 :
小鼠
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 22
参考文献 |
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Noelle R, Roy M, Shepherd D, Stamenkovico I, Ledbetter J, Aruffo A. Pillars Article: A 39-kDa Protein on Activated Helper T Cells Binds CD40 and Transduces the Signal for Cognate Activation of B Cells. Proc. Natl. Acad. Sci. 1992. 89: 6550-6554. J Immunol. 2016;197:4195-4199 pubmed
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Llopiz D, Huarte E, Ruiz M, Bezunartea J, Belsue V, Zabaleta A, et al. Helper cell-independent antitumor activity of potent CD8+ T cell epitope peptide vaccines is dependent upon CD40L. Oncoimmunology. 2013;2:e27009 pubmed
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Bahjat K, Liu W, Lemmens E, Schoenberger S, Portnoy D, Dubensky T, et al. Cytosolic entry controls CD8+-T-cell potency during bacterial infection. Infect Immun. 2006;74:6387-97 pubmed
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Lesley R, Kelly L, Xu Y, Cyster J. Naive CD4 T cells constitutively express CD40L and augment autoreactive B cell survival. Proc Natl Acad Sci U S A. 2006;103:10717-22 pubmed
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Roy M, Waldschmidt T, Aruffo A, Ledbetter J, Noelle R. The regulation of the expression of gp39, the CD40 ligand, on normal and cloned CD4+ T cells. J Immunol. 1993;151:2497-510 pubmed
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van den Eertwegh A, Noelle R, Roy M, Shepherd D, Aruffo A, Ledbetter J, et al. In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate T-B cell interactions. J Exp Med. 1993;178:1555-65 pubmed
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Roy M, Aruffo A, Ledbetter J, Linsley P, Kehry M, Noelle R. Studies on the interdependence of gp39 and B7 expression and function during antigen-specific immune responses. Eur J Immunol. 1995;25:596-603 pubmed
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Yellin M, Sippel K, Inghirami G, Covey L, Lee J, Sinning J, et al. CD40 molecules induce down-modulation and endocytosis of T cell surface T cell-B cell activating molecule/CD40-L. Potential role in regulating helper effector function. J Immunol. 1994;152:598-608 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
CD154 (CD40 Ligand) Monoclonal Antibody (MR1), PE, eBioscience™
目录# :
12-1541-81
规格 :
50微克
价格 :
美国126
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
亚美尼亚仓鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.25 µg/test
物种 :
小鼠
克隆 :
MR1
抗体亚型 :
IgG
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
CD40 Ligand (CD40-L), or CD154, is a membrane glycoprotein and differentiation antigen expressed on the surface of T cells. The CD40 Ligand stimulates B cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40 Ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also co-stimulates proliferation of activated T cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL-2.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.25 µg/test
别名 :
CD154; CD40 antigen ligand; CD40 ligand; CD40 ligand CD154; CD40 ligand, membrane form; CD40 ligand, soluble form; Cd40l; CD40-L; CD40LG; gp39; hCD40L; H-CD-40-L; HIGM1; IGM; IMD3; Ly62; Ly-62; M-CD-40-L; RP23-153G22.3; T-B cell-activating molecule; T-BAM; T-cell antigen Gp39; TNF-related activation protein; Tnfsf5; TRAP; tumor necrosis factor (ligand) superfamily member 5; tumor necrosis factor (ligand) superfamily, member 5; tumor necrosis factor ligand superfamily member 5
更多信息或购买 :
公司信息
赛默飞世尔
产品浏览
- CD154 (CD40 Ligand) Monoclonal Antibody (MR1), PE, eBioscience™ | 12-1541-82
- CD154 (CD40 Ligand) Monoclonal Antibody (MR1), PE, eBioscience™ | 12-1541-83
- CD154 (CD40 Ligand) Monoclonal Antibody (24-31), PE, eBioscience™ | 12-1548-42
- CD157 Monoclonal Antibody (eBioSY11B5 (SY11B5)), PE, eBioscience™ | 12-1579-41
- CD157 Monoclonal Antibody (eBioSY11B5 (SY11B5)), PE, eBioscience™ | 12-1579-42
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