产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
FOXP3 Monoclonal Antibody (NRRF-30), PE, eBioscience
目录 :
12-4771-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
PE
克隆名称 :
NRRF-30
反应物种 :
小鼠
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 62
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 5a, 5c
Lu L, Li T, Feng X, Liu Z, Liu Y, Chao T, et al. Excessive immunosuppression by regulatory T cells antagonizes T cell response to schistosome infection in PD-1-deficient mice. PLoS Pathog. 2022;18:e1010596 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Patel M, Kim J, Theodros D, Tam A, Velarde E, Kochel C, et al. Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma. J Immunother Cancer. 2016;4:28 pubmed 出版商
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Tan Y, Ding Y, Zheng X, Dai G, Zhang S, Yang X, et al. Ding's herbal enema treats dextran sulfate sodium-induced colitis in mice by regulating the gut microbiota and maintaining the Treg/Th17 cell balance. Exp Ther Med. 2021;22:1368 pubmed 出版商
Porsche C, Delproposto J, Geletka L, O ROURKE R, Lumeng C. Obesity results in adipose tissue T cell exhaustion. JCI Insight. 2021;6: pubmed 出版商
De Martino M, Daviaud C, Diamond J, Kraynak J, Alard A, Formenti S, et al. Activin A Promotes Regulatory T-cell-Mediated Immunosuppression in Irradiated Breast Cancer. Cancer Immunol Res. 2021;9:89-102 pubmed 出版商
Liu Y, Yin Z, Lu P, Ma Y, Luo B, Xiang L, et al. Lung Carcinoma Cells Secrete Exosomal MALAT1 to Inhibit Dendritic Cell Phagocytosis, Inflammatory Response, Costimulatory Molecule Expression and Promote Dendritic Cell Autophagy via AKT/mTOR Pathway. Onco Targets Ther. 2020;13:10693-10705 pubmed 出版商
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Yang R, Huang H, Cui S, Zhou Y, Zhang T, Zhou Y. IFN-γ promoted exosomes from mesenchymal stem cells to attenuate colitis via miR-125a and miR-125b. Cell Death Dis. 2020;11:603 pubmed 出版商
Ko J, Kim H, Jeong H, Lee H, Oh J. Mesenchymal Stem and Stromal Cells Harness Macrophage-Derived Amphiregulin to Maintain Tissue Homeostasis. Cell Rep. 2020;30:3806-3820.e6 pubmed 出版商
Porsche C, Delproposto J, Patrick E, Zamarron B, Lumeng C. Adipose tissue dendritic cell signals are required to maintain T cell homeostasis and obesity-induced expansion. Mol Cell Endocrinol. 2020;505:110740 pubmed 出版商
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Lee H, Kim K, Ryu J, Jeong H, Lee S, Kim M. Bilateral Effect of the Unilateral Corneal Nerve Cut on Both Ocular Surface and Lacrimal Gland. Invest Ophthalmol Vis Sci. 2019;60:430-441 pubmed 出版商
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Wang T, Wang D, Yu H, Feng B, Zhou F, Zhang H, et al. A cancer vaccine-mediated postoperative immunotherapy for recurrent and metastatic tumors. Nat Commun. 2018;9:1532 pubmed 出版商
Turaj A, Hussain K, Cox K, Rose Zerilli M, Testa J, Dahal L, et al. Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment. Cancer Cell. 2017;32:777-791.e6 pubmed 出版商
Hu X, Li X, Hu C, Qin L, He R, Luo L, et al. Respiratory Syncytial Virus Exacerbates OVA-mediated asthma in mice through C5a-C5aR regulating CD4+T cells Immune Responses. Sci Rep. 2017;7:15207 pubmed 出版商
Porchia B, Moreno A, Ramos R, Diniz M, de Andrade L, Rosa D, et al. Herpes Simplex Virus Glycoprotein D Targets a Specific Dendritic Cell Subset and Improves the Performance of Vaccines to Human Papillomavirus-Associated Tumors. Mol Cancer Ther. 2017;16:1922-1933 pubmed 出版商
Chen Q, Xu L, Liang C, Wang C, Peng R, Liu Z. Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy. Nat Commun. 2016;7:13193 pubmed 出版商
Marinho F, Alves C, de Souza S, da Silva C, Cassali G, Oliveira S, et al. Schistosoma mansoni Tegument (Smteg) Induces IL-10 and Modulates Experimental Airway Inflammation. PLoS ONE. 2016;11:e0160118 pubmed 出版商
Andersson S, Eneljung T, Tengvall S, Jirholt P, Stern A, Henningsson L, et al. Collagen epitope expression on B cells is sufficient to confer tolerance to collagen-induced arthritis. Arthritis Res Ther. 2016;18:140 pubmed 出版商
Tengvall S, Eneljung T, Jirholt P, Turesson O, Wing K, Holmdahl R, et al. Gene Therapy Induces Antigen-Specific Tolerance in Experimental Collagen-Induced Arthritis. PLoS ONE. 2016;11:e0154630 pubmed 出版商
Li Y, Fang M, Zhang J, Wang J, Song Y, Shi J, et al. Hydrogel dual delivered celecoxib and anti-PD-1 synergistically improve antitumor immunity. Oncoimmunology. 2016;5:e1074374 pubmed
Kim W, Kim J, Cha S, Han S, Kim H, Kwon K, et al. Virulence-Dependent Alterations in the Kinetics of Immune Cells during Pulmonary Infection by Mycobacterium tuberculosis. PLoS ONE. 2015;10:e0145234 pubmed 出版商
Pallangyo C, Ziegler P, Greten F. IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis. J Exp Med. 2015;212:2253-66 pubmed 出版商
Lee S, Park H, Jeon S, Lee C, Seong R, Park S, et al. Ubiquitous Over-Expression of Chromatin Remodeling Factor SRG3 Ameliorates the T Cell-Mediated Exacerbation of EAE by Modulating the Phenotypes of both Dendritic Cells and Macrophages. PLoS ONE. 2015;10:e0132329 pubmed 出版商
Devaud C, Yong C, John L, Westwood J, Duong C, House C, et al. Foxp3 expression in macrophages associated with RENCA tumors in mice. PLoS ONE. 2014;9:e108670 pubmed 出版商
Maneva Radicheva L, Amatya C, Parker C, Ellefson J, Radichev I, Raghavan A, et al. Autoimmune diabetes is suppressed by treatment with recombinant human tissue Kallikrein-1. PLoS ONE. 2014;9:e107213 pubmed 出版商
Chan M, Chang C, Tung C, Sun J, Suen J, Wu S. Low-dose 5-aza-2'-deoxycytidine pretreatment inhibits experimental autoimmune encephalomyelitis by induction of regulatory T cells. Mol Med. 2014;20:248-56 pubmed 出版商
Eneljung T, Tengvall S, Jirholt P, Henningsson L, Holmdahl R, Gustafsson K, et al. Antigen-specific gene therapy after immunisation reduces the severity of collagen-induced arthritis. Clin Dev Immunol. 2013;2013:345092 pubmed 出版商
Wong L, HATFIELD J, Brown M. Ikaros sets the potential for Th17 lineage gene expression through effects on chromatin state in early T cell development. J Biol Chem. 2013;288:35170-9 pubmed 出版商
Yolcu E, Kaminitz A, Mizrahi K, Ash S, Yaniv I, Stein J, et al. Immunomodulation with donor regulatory T cells armed with Fas-ligand alleviates graft-versus-host disease. Exp Hematol. 2013;41:903-11 pubmed 出版商
Kaminitz A, Yolcu E, Mizrahi K, Shirwan H, Askenasy N. Killer Treg cells ameliorate inflammatory insulitis in non-obese diabetic mice through local and systemic immunomodulation. Int Immunol. 2013;25:485-94 pubmed 出版商
Amoah S, Holbrook B, Yammani R, Alexander Miller M. High viral burden restricts short-lived effector cell number at late times postinfection through increased natural regulatory T cell expansion. J Immunol. 2013;190:5020-9 pubmed 出版商
Kim M, Kim T. R-phycoerythrin-conjugated antibodies are inappropriate for intracellular staining of murine plasma cells. Cytometry A. 2013;83:452-60 pubmed 出版商
Tasso R, Ilengo C, Quarto R, Cancedda R, Caspi R, Pennesi G. Mesenchymal stem cells induce functionally active T-regulatory lymphocytes in a paracrine fashion and ameliorate experimental autoimmune uveitis. Invest Ophthalmol Vis Sci. 2012;53:786-93 pubmed 出版商
Yarkoni S, Prigozhina T, Slavin S, Askenasy N. IL-2-targeted therapy ameliorates the severity of graft-versus-host disease: ex vivo selective depletion of host-reactive T cells and in vivo therapy. Biol Blood Marrow Transplant. 2012;18:523-35 pubmed 出版商
Younes S, Punkosdy G, Caucheteux S, Chen T, Grossman Z, Paul W. Memory phenotype CD4 T cells undergoing rapid, nonburst-like, cytokine-driven proliferation can be distinguished from antigen-experienced memory cells. PLoS Biol. 2011;9:e1001171 pubmed 出版商
Rowswell Turner R, Harden J, Nair R, Gu T, Kilinc M, Egilmez N. Chronic chemoimmunotherapy achieves cure of spontaneous murine mammary tumors via persistent blockade of posttherapy counter-regulation. J Immunol. 2011;187:4109-18 pubmed 出版商
Whitehead G, Wilson R, Nakano K, Burch L, Nakano H, Cook D. IL-35 production by inducible costimulator (ICOS)-positive regulatory T cells reverses established IL-17-dependent allergic airways disease. J Allergy Clin Immunol. 2012;129:207-15.e1-5 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
FOXP3 Monoclonal Antibody (NRRF-30), PE, eBioscience
目录# :
12-4771-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.25 µg/test
物种 :
小鼠
克隆 :
NRRF-30
抗体亚型 :
IgG2a, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
FOXP3 (Forkhead box protein 3) is a member of the forkhead/winged-helix family of transcriptional regulators, highly conserved across mammals, and essential for normal immune homeostasis. FOXP3 is 381 amino acids long, stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene, and a more specific marker of regulatory T cells. Defects in the gene encoding FOXP3 protein cause the scurfy phenotype in mice. In humans FOXP3 defects play a role in IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-linked syndrome), also known as X-linked autoimmunity-allergic dysregulation (XLAAD) syndrome. Transcript variants of FOXP3 encoding different isoforms have been identified. In human breast and colon cancer cells, expression of FOXP3 is regulated by p53 in response to the DNA damage.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.25 µg/test
别名 :
AIID; DIETER; forkhead box P3; forkhead box protein P3; Forkhead box protein P3 41 kDa form; Forkhead box protein P3, C-terminally processed; forkhead/winged helix transcription factor 3; Foxp3; FOXP3delta7; immune dysregulation, polyendocrinopathy, enteropathy, X-linked; immunodeficiency, polyendocrinopathy, enteropathy, X-linked; IPEX; JM2; MGC141961; MGC141963; PIDX; regulatory protein Foxp3; RGD1562112; RP23-54C14.1; scurfin; scurfy; sf; XPID
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国