产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Podoplanin Monoclonal Antibody (eBio8.1.1 (8.1.1)), PE, eBioscience™
目录 :
12-5381-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
Syrian golden hamster
共轭标签 :
PE
克隆名称 :
eBio8.1。 1(8.1。 1)
反应物种 :
小鼠
应用 :
免疫组化, 流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 22
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 1:100; 图 s6a
Hu X, Deng Q, Ma L, Li Q, Chen Y, Liao Y, et al. Meningeal lymphatic vessels regulate brain tumor drainage and immunity. Cell Res. 2020;30:229-243 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 s2e
Louveau A, Herz J, Alme M, Salvador A, Dong M, Viar K, et al. CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature. Nat Neurosci. 2018;21:1380-1391 pubmed 出版商
Frye M, Stritt S, Ortsäter H, Hernandez Vasquez M, Kaakinen M, Vicente A, et al. EphrinB2-EphB4 signalling provides Rho-mediated homeostatic control of lymphatic endothelial cell junction integrity. elife. 2020;9: pubmed 出版商
Fujimoto N, He Y, D Addio M, Tacconi C, Detmar M, Dieterich L. Single-cell mapping reveals new markers and functions of lymphatic endothelial cells in lymph nodes. PLoS Biol. 2020;18:e3000704 pubmed 出版商
Trevejo Nuñez G, Elsegeiny W, Aggor F, Tweedle J, Kaplan Z, Gandhi P, et al. Interleukin-22 (IL-22) Binding Protein Constrains IL-22 Activity, Host Defense, and Oxidative Phosphorylation Genes during Pneumococcal Pneumonia. Infect Immun. 2019;87: pubmed 出版商
Obulkasim H, Shi X, Wang J, Li J, Dai B, Wu P, et al. Podoplanin is an important stromal prognostic marker in perihilar cholangiocarcinoma. Oncol Lett. 2018;15:137-146 pubmed 出版商
Eddens T, Elsegeiny W, Garcia Hernadez M, Castillo P, Trevejo Nuñez G, Serody K, et al. Pneumocystis-Driven Inducible Bronchus-Associated Lymphoid Tissue Formation Requires Th2 and Th17 Immunity. Cell Rep. 2017;18:3078-3090 pubmed 出版商
Dieterich L, Ikenberg K, Cetintas T, Kapaklikaya K, Hutmacher C, Detmar M. Tumor-Associated Lymphatic Vessels Upregulate PDL1 to Inhibit T-Cell Activation. Front Immunol. 2017;8:66 pubmed 出版商
Gurung H, Carr M, Carr D. Cornea lymphatics drive the CD8+ T-cell response to herpes simplex virus-1. Immunol Cell Biol. 2017;95:87-98 pubmed 出版商
Blanco S, Bandiera R, Popis M, Hussain S, Lombard P, Aleksic J, et al. Stem cell function and stress response are controlled by protein synthesis. Nature. 2016;534:335-40 pubmed 出版商
Klein S, Dieterich L, Mathelier A, Chong C, Sliwa Primorac A, Hong Y, et al. DeepCAGE transcriptomics identify HOXD10 as a transcription factor regulating lymphatic endothelial responses to VEGF-C. J Cell Sci. 2016;129:2573-85 pubmed 出版商
Loder S, Agarwal S, Sorkin M, Breuler C, Li J, Peterson J, et al. Lymphatic Contribution to the Cellular Niche in Heterotopic Ossification. Ann Surg. 2016;264:1174-1180 pubmed
Chimen M, McGettrick H, Apta B, Kuravi S, Yates C, Kennedy A, et al. Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease. Nat Med. 2015;21:467-475 pubmed 出版商
Lee M, Kiefel H, LaJevic M, Macauley M, Kawashima H, O Hara E, et al. Transcriptional programs of lymphoid tissue capillary and high endothelium reveal control mechanisms for lymphocyte homing. Nat Immunol. 2014;15:982-95 pubmed 出版商
Bénézech C, Nayar S, Finney B, Withers D, Lowe K, Desanti G, et al. CLEC-2 is required for development and maintenance of lymph nodes. Blood. 2014;123:3200-7 pubmed 出版商
Desai T, Brownfield D, Krasnow M. Alveolar progenitor and stem cells in lung development, renewal and cancer. Nature. 2014;507:190-4 pubmed 出版商
Askovich P, Sanders C, Rosenberger C, Diercks A, Dash P, Navarro G, et al. Differential host response, rather than early viral replication efficiency, correlates with pathogenicity caused by influenza viruses. PLoS ONE. 2013;8:e74863 pubmed 出版商
Chamoto K, Gibney B, Ackermann M, Lee G, Konerding M, Tsuda A, et al. Alveolar epithelial dynamics in postpneumonectomy lung growth. Anat Rec (Hoboken). 2013;296:495-503 pubmed 出版商
Chamoto K, Gibney B, Lee G, Ackermann M, Konerding M, Tsuda A, et al. Migration of CD11b+ accessory cells during murine lung regeneration. Stem Cell Res. 2013;10:267-77 pubmed 出版商
Finney B, Schweighoffer E, Navarro Nuñez L, Bénézech C, Barone F, Hughes C, et al. CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development. Blood. 2012;119:1747-56 pubmed 出版商
Farr A, Berry M, Kim A, Nelson A, Welch M, Aruffo A. Characterization and cloning of a novel glycoprotein expressed by stromal cells in T-dependent areas of peripheral lymphoid tissues. J Exp Med. 1992;176:1477-82 pubmed
Farr A, Nelson A, Hosier S. Characterization of an antigenic determinant preferentially expressed by type I epithelial cells in the murine thymus. J Histochem Cytochem. 1992;40:651-64 pubmed
产品信息
产品类型 :
抗体
产品名称 :
Podoplanin Monoclonal Antibody (eBio8.1.1 (8.1.1)), PE, eBioscience™
目录# :
12-5381-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
Syrian Hamster
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.25 µg/test
物种 :
小鼠
克隆 :
eBio8.1。 1(8.1。 1)
抗体亚型 :
IgG
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
Podoplanin (PDPN, T1A, gp38, Aggrus) is a mucin type-1 glycoprotein with a 40-43 kDa molecular weight. Podoplanin is expressed in many tumors and normal cells, especially lymphatic epithelial cells and follicular DCs. Podoplanin localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. Podoplanin appears to serve as a ligand for CLEC-2 and expression is positively correlated with tumors expressing greater invasive and metastatic potential. Podoplanin is directly involved in cell migration, aids metastases formation and tumor cell invasion of tissue. Further, it has also been determined that podoplanin expression is induced through Src activation of Cas and, recently, there are indications of podoplanin presence on Th17 cells. Initial studies below indicate the presence of podoplanin on a small but distinct population of CD4+ cells from human PBMC. Dysfunction of the podoplanin protein has been linked to diseases such as lymphangioma and subglottis neoplasm. Podoplanin has also been proposed as a marker for lung injury due to the physiological function of the protein.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.25 µg/test
别名 :
29kDa cytosolic podoplanin intracellular domain; Aggrus; CTA-520D8.1; E11; E11 antigen epitope; epithelial cell surface transmembrane protein antigen; glycoprotein 36; Glycoprotein 38; glycoprotein, 36-KD; GP36; Gp38; GP40; HT1A-1; hT1alpha-1; hT1alpha-2; lung type I cell membrane associated glycoprotein; lung type-I cell membrane-associated glycoprotein (T1A-2); Ots8; OTS-8; OTTHUMP00000009640; OTTHUMP00000044504; PA2.26; PA2.26 antigen; PDPN; PICD; Podoplanin; PSEC0003; PSEC0025; pulmonary type I alveolar epithelial cell transmembrane differentiation marker; RANDAM-2; RP23-348F1.2; RTI140; RTI40; T1a; T1A2; T1A-2; T1alpha; T1-alpha; TI1A; Transmembrane glycoprotein E11; type I cell 40 kDa protein
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国