产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
NOTCH1 Monoclonal Antibody (mN1A), PE, eBioscience™
目录 :
12-5785-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
PE
克隆名称 :
mN1A
反应物种 :
人类, 小鼠
应用 :
流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 7
参考文献
Di Ianni M, Baldoni S, Del Papa B, Aureli P, Dorillo E, De Falco F, et al. NOTCH1 Is Aberrantly Activated in Chronic Lymphocytic Leukemia Hematopoietic Stem Cells. Front Oncol. 2018;8:105 pubmed 出版商
Xiong H, Maraver A, Latkowski J, Henderson T, Schlessinger K, Ding Y, et al. Characterization of two distinct lymphoproliferative diseases caused by ectopic expression of the Notch ligand DLL4 on T cells. PLoS ONE. 2013;8:e84841 pubmed 出版商
Perumalsamy L, Marcel N, Kulkarni S, Radtke F, Sarin A. Distinct spatial and molecular features of notch pathway assembly in regulatory T cells. Sci Signal. 2012;5:ra53 pubmed 出版商
Keerthivasan S, Suleiman R, Lawlor R, Roderick J, Bates T, Minter L, et al. Notch signaling regulates mouse and human Th17 differentiation. J Immunol. 2011;187:692-701 pubmed 出版商
Cabezón R, Sintes J, Llinàs L, Benitez Ribas D. Analysis of HLDA9 mAbs on plasmacytoid dendritic cells. Immunol Lett. 2011;134:167-73 pubmed 出版商
Yan H, Blackburn A, McLary S, Tao L, Roberts A, Xavier E, et al. Pathways contributing to development of spontaneous mammary tumors in BALB/c-Trp53+/- mice. Am J Pathol. 2010;176:1421-32 pubmed 出版商
Luis T, Weerkamp F, Naber B, Baert M, de Haas E, Nikolic T, et al. Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation. Blood. 2009;113:546-54 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
NOTCH1 Monoclonal Antibody (mN1A), PE, eBioscience™
目录# :
12-5785-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类, 小鼠
应用 :
Flow Cytometry: 0.25 µg/test
物种 :
人类, 小鼠
克隆 :
mN1A
抗体亚型 :
IgG1, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
The notch gene belongs to a family of epidermal growth factor (EGF) like homeotic genes, which encode transmembrane proteins with a variable number of cysteine-rich EGF-like repeats in the extracellular region. Four notch genes have been described in mammals: Notch1, Notch2, Notch3 and Notch4(Int-3), which have been implicated in the differentiation of the nervous system and other structures. The EGF-like proteins Delta and Serrate have been identified as ligands of Notch1. Mature Notch proteins are heterodimeric receptors derived from the cleavage of Notch pre-proteins into an extracellular subunit (NEC) containing multiple EGF-like repeats and a transmembrane subunit including intracellular region (Ntm).
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.25 µg/test
别名 :
9930111A19Rik; AOS5; AOVD1; Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila); hN1; lin-12; major type A protein; Mis6; Motch; Motch A; mT14; N1; neurogenic locus notch homolog protein 1; NEXT; NICD; NOTCH; notch 1; Notch 1 extracellular truncation; Notch 1 intracellular domain; Notch gene homolog 1; Notch homolog 1, translocation-associated; notch receptor 1; Notch1; p300; RP23-306D20.12; RP23-306D20.12-001; Tan1; Translocation-associated notch protein TAN-1; transmembrane receptor Notch1
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国