产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD49b (Integrin alpha 2) Monoclonal Antibody (DX5), PE, eBioscience™
目录 :
12-5971-81
规格 :
50微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
PE
克隆名称 :
DX5
反应物种 :
小鼠
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 57
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 5
Yan S, Wang L, Liu N, Wang Y, Chu Y. Critical role of interleukin-17/interleukin-17 receptor axis in mediating Con A-induced hepatitis. Immunol Cell Biol. 2012;90:421-8 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
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  • 流式细胞仪; 小鼠
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Zhang X, Feng J, Chen S, Yang H, Dong Z. Synergized regulation of NK cell education by NKG2A and specific Ly49 family members. Nat Commun. 2019;10:5010 pubmed 出版商
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Krneta T, Gillgrass A, Chew M, Ashkar A. The breast tumor microenvironment alters the phenotype and function of natural killer cells. Cell Mol Immunol. 2016;13:628-39 pubmed 出版商
Gowdy K, Martinu T, Nugent J, Manzo N, Zhang H, Kelly F, et al. Impaired CD8(+) T cell immunity after allogeneic bone marrow transplantation leads to persistent and severe respiratory viral infection. Transpl Immunol. 2015;32:51-60 pubmed 出版商
Rosenstein R, Bezbradica J, Yu S, Medzhitov R. Signaling pathways activated by a protease allergen in basophils. Proc Natl Acad Sci U S A. 2014;111:E4963-71 pubmed 出版商
Chu D, Mohammed Ali Z, Jiménez Saiz R, Walker T, Goncharova S, Llop Guevara A, et al. T helper cell IL-4 drives intestinal Th2 priming to oral peanut antigen, under the control of OX40L and independent of innate-like lymphocytes. Mucosal Immunol. 2014;7:1395-404 pubmed 出版商
Miller J, Sack B, Baldwin M, Vaughan A, Kappe S. Interferon-mediated innate immune responses against malaria parasite liver stages. Cell Rep. 2014;7:436-447 pubmed 出版商
Stoermer Burrack K, Hawman D, Jupille H, Oko L, Minor M, Shives K, et al. Attenuating mutations in nsP1 reveal tissue-specific mechanisms for control of Ross River virus infection. J Virol. 2014;88:3719-32 pubmed 出版商
Weinkopff T, de Oliveira C, de Carvalho A, Hauyon La Torre Y, Muniz A, Miranda J, et al. Repeated exposure to Lutzomyia intermedia sand fly saliva induces local expression of interferon-inducible genes both at the site of injection in mice and in human blood. PLoS Negl Trop Dis. 2014;8:e2627 pubmed 出版商
Qin X, Liu X, Shan B, Shi L, Sharma S, Wu J, et al. Inhibition of eIF5A results in aberrant uterine natural killer cell function and embryo loss in mice. Am J Reprod Immunol. 2014;71:229-40 pubmed 出版商
Gaston D, Odom C, Li L, Markert J, Roth J, Cassady K, et al. Production of bioactive soluble interleukin-15 in complex with interleukin-15 receptor alpha from a conditionally-replicating oncolytic HSV-1. PLoS ONE. 2013;8:e81768 pubmed 出版商
Rubinstein M, Salem M, Doedens A, Moore C, Chiuzan C, Rivell G, et al. G-CSF/anti-G-CSF antibody complexes drive the potent recovery and expansion of CD11b+Gr-1+ myeloid cells without compromising CD8+ T cell immune responses. J Hematol Oncol. 2013;6:75 pubmed 出版商
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Takashima A, Ishikawa F, Kuwabara T, Tanaka Y, Kinoshita T, Ito M, et al. Uterine natural killer cells severely decrease in number at gestation day 6 in mice. Biol Reprod. 2013;89:101 pubmed 出版商
Bulliard Y, Jolicoeur R, Windman M, Rue S, Ettenberg S, Knee D, et al. Activating Fc ? receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies. J Exp Med. 2013;210:1685-93 pubmed 出版商
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Metcalf D, Ng A, Baldwin T, Di Rago L, Mifsud S. Concordant mast cell and basophil production by individual hematopoietic blast colony-forming cells. Proc Natl Acad Sci U S A. 2013;110:9031-5 pubmed 出版商
Grothusen C, Schuett H, Hillmer A, Lumpe S, Grote K, Ballmaier M, et al. Role of suppressor of cytokine signaling-1 in murine atherosclerosis. PLoS ONE. 2012;7:e51608 pubmed 出版商
Shiraishi Y, Jia Y, Domenico J, Joetham A, Karasuyama H, Takeda K, et al. Sequential engagement of Fc?RI on Mast Cells and Basophil Histamine H(4) Receptor and Fc?RI in Allergic Rhinitis. J Immunol. 2013;190:539-48 pubmed 出版商
Dighe A, Yang S, Madhu V, Balian G, Cui Q. Interferon gamma and T cells inhibit osteogenesis induced by allogeneic mesenchymal stromal cells. J Orthop Res. 2013;31:227-34 pubmed 出版商
Goulding J, Bogue R, Tahiliani V, Croft M, Salek Ardakani S. CD8 T cells are essential for recovery from a respiratory vaccinia virus infection. J Immunol. 2012;189:2432-40 pubmed 出版商
Monnier J, Lewén S, O Hara E, Huang K, Tu H, Butcher E, et al. Expression, regulation, and function of atypical chemerin receptor CCRL2 on endothelial cells. J Immunol. 2012;189:956-67 pubmed 出版商
Klezovich Bénard M, Corre J, Jusforgues Saklani H, Fiole D, Burjek N, Tournier J, et al. Mechanisms of NK cell-macrophage Bacillus anthracis crosstalk: a balance between stimulation by spores and differential disruption by toxins. PLoS Pathog. 2012;8:e1002481 pubmed 出版商
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产品信息
产品类型 :
抗体
产品名称 :
CD49b (Integrin alpha 2) Monoclonal Antibody (DX5), PE, eBioscience™
目录# :
12-5971-81
规格 :
50微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.5 µg/test
物种 :
小鼠
克隆 :
DX5
抗体亚型 :
IgM, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
CD49b (Integrin alpha 2, Integrin alpha 2 chain, VLA-2 alpha chain, HM alpha 2) is a member of the integrin family. It is a glycoprotein with molecular weight of 150 kD, and it complexes with CD29 (Integrin beta 1) to form the heterodimeric integrin VLA-2 (integrin alpha 2 beta 1, or GPIa/IIa) complex. VLA-2 is an extracellular receptor for laminin, collagen, and fibronectin, and interaction with its ligands results in the activation of intracellular signaling pathways. It has reported roles in VEGF-induced angiogenesis in vivo, as well as adhesion and lymphocyte activation. CD49b is expressed by NK cells, NK-T cells, monocytes, platelets, and epithelial cells. It is also expressed on adaptive immune cells such as T and B cells, specifically on a subset of CD4+ T cells in the spleen, on intraepithelial and lamina propria lymphocytes in the intestine, as well as on a population of peripheral CD4+ type 1 T regulatory (Tr1) cells that co-express LAG-3.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.5 µg/test
别名 :
alpha 2 subunit of VLA-2 receptor; BDPLT9; BR; CD49 antigen-like family member B; CD49B; Collagen receptor; DX5; GPIa; HPA-5; human platelet alloantigen system 5; integrin alpha 2; integrin alpha-2; integrin subunit alpha 2; integrin, alpha 2; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); Itga2; platelet antigen Br; platelet glycoprotein GPIa; platelet membrane glycoprotein Ia; very late activation protein 2 receptor, alpha-2 subunit; VLA-2; VLA2 receptor; VLA-2 receptor, alpha 2 subunit; VLA-2 subunit alpha; VLAA2
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国