产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD338 (ABCG2) Monoclonal Antibody (5D3), PE, eBioscience
目录 :
12-8888-42
规格 :
100试验
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
PE
克隆名称 :
5D3
反应物种 :
人类
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 25
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 1
Kumar J, Wei B, Madigan J, Simpson R, Hall M, Gottesman M. Bioluminescent imaging of ABCG2 efflux activity at the blood-placenta barrier. Sci Rep. 2016;6:20418 pubmed 出版商
Feng D, Yan K, Liang H, Liang J, Wang W, Yu H, et al. CBP-mediated Wnt3a/β-catenin signaling promotes cervical oncogenesis initiated by Piwil2. Neoplasia. 2021;23:1-11 pubmed 出版商
Ito D, Childress M, Mason N, Winter A, O BRIEN T, Henson M, et al. A double blinded, placebo-controlled pilot study to examine reduction of CD34 +/CD117 +/CD133 + lymphoma progenitor cells and duration of remission induced by neoadjuvant valspodar in dogs with large B-cell lymphoma. F1000Res. 2015;4:42 pubmed 出版商
Feng D, Yan K, Zhou Y, Liang H, Liang J, Zhao W, et al. Piwil2 is reactivated by HPV oncoproteins and initiates cell reprogramming via epigenetic regulation during cervical cancer tumorigenesis. Oncotarget. 2016;7:64575-64588 pubmed 出版商
Weidner L, Fung K, Kannan P, Moen J, Kumar J, Mulder J, et al. Tariquidar Is an Inhibitor and Not a Substrate of Human and Mouse P-glycoprotein. Drug Metab Dispos. 2016;44:275-82 pubmed 出版商
Fung K, Kapoor K, Pixley J, Talbert D, Kwit A, Ambudkar S, et al. Using the BacMam Baculovirus System to Study Expression and Function of Recombinant Efflux Drug Transporters in Polarized Epithelial Cell Monolayers. Drug Metab Dispos. 2016;44:180-8 pubmed 出版商
GORDEN B, Saha J, Khammanivong A, Schwartz G, Dickerson E. Lysosomal drug sequestration as a mechanism of drug resistance in vascular sarcoma cells marked by high CSF-1R expression. Vasc Cell. 2014;6:20 pubmed 出版商
Marriott S, Baskir R, Gaskill C, Menon S, Carrier E, Williams J, et al. ABCG2pos lung mesenchymal stem cells are a novel pericyte subpopulation that contributes to fibrotic remodeling. Am J Physiol Cell Physiol. 2014;307:C684-98 pubmed 出版商
To K, Tomlinson B. Targeting the ABCG2-overexpressing multidrug resistant (MDR) cancer cells by PPAR? agonists. Br J Pharmacol. 2013;170:1137-51 pubmed 出版商
Yang W, Song M, Park E, Lee J, Park J, Park K, et al. Transcription factors Sp1 and Sp3 regulate expression of human ABCG2 gene and chemoresistance phenotype. Mol Cells. 2013;36:368-75 pubmed 出版商
Cannon C, Pozniak J, Scott M, Ito D, Gorden B, Graef A, et al. Canine osteosarcoma cells exhibit resistance to aurora kinase inhibitors. Vet Comp Oncol. 2015;13:48-59 pubmed 出版商
Foster B, Gangavarapu K, Mathew G, Azabdaftari G, Morrison C, Miller A, et al. Human prostate side population cells demonstrate stem cell properties in recombination with urogenital sinus mesenchyme. PLoS ONE. 2013;8:e55062 pubmed 出版商
Das S, Hermanson D, Bleeker N, Lowman X, Li Y, Kelekar A, et al. Ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017): a novel scaffold that resensitizes multidrug resistant leukemia cells to chemotherapy. ACS Chem Biol. 2013;8:327-35 pubmed 出版商
Padmanabhan R, Chen K, Gillet J, Handley M, Mallon B, Hamilton R, et al. Regulation and expression of the ATP-binding cassette transporter ABCG2 in human embryonic stem cells. Stem Cells. 2012;30:2175-87 pubmed 出版商
Cheng G, To K. Adverse Cell Culture Conditions Mimicking the Tumor Microenvironment Upregulate ABCG2 to Mediate Multidrug Resistance and a More Malignant Phenotype. ISRN Oncol. 2012;2012:746025 pubmed 出版商
Wei Y, Ma Y, Zhao Q, Ren Z, Li Y, Hou T, et al. New use for an old drug: inhibiting ABCG2 with sorafenib. Mol Cancer Ther. 2012;11:1693-702 pubmed 出版商
Dhanasekaran M, Indumathi S, Kanmani A, Poojitha R, Revathy K, Rajkumar J, et al. Surface antigenic profiling of stem cells from human omentum fat in comparison with subcutaneous fat and bone marrow. Cytotechnology. 2012;: pubmed
Ni Z, Bikadi Z, Shuster D, Zhao C, Rosenberg M, Mao Q. Identification of proline residues in or near the transmembrane helices of the human breast cancer resistance protein (BCRP/ABCG2) that are important for transport activity and substrate specificity. Biochemistry. 2011;50:8057-66 pubmed 出版商
Goler Baron V, Assaraf Y. Structure and function of ABCG2-rich extracellular vesicles mediating multidrug resistance. PLoS ONE. 2011;6:e16007 pubmed 出版商
Ni Z, Bikadi Z, Cai X, Rosenberg M, Mao Q. Transmembrane helices 1 and 6 of the human breast cancer resistance protein (BCRP/ABCG2): identification of polar residues important for drug transport. Am J Physiol Cell Physiol. 2010;299:C1100-9 pubmed 出版商
Cai X, Bikadi Z, Ni Z, Lee E, Wang H, Rosenberg M, et al. Role of basic residues within or near the predicted transmembrane helix 2 of the human breast cancer resistance protein in drug transport. J Pharmacol Exp Ther. 2010;333:670-81 pubmed 出版商
Polgar O, Ediriwickrema L, Robey R, Sharma A, Hegde R, Li Y, et al. Arginine 383 is a crucial residue in ABCG2 biogenesis. Biochim Biophys Acta. 2009;1788:1434-43 pubmed 出版商
Bram E, Adar Y, Mesika N, Sabisz M, Skladanowski A, Assaraf Y. Structural determinants of imidazoacridinones facilitating antitumor activity are crucial for substrate recognition by ABCG2. Mol Pharmacol. 2009;75:1149-59 pubmed 出版商
Robey R, Obrzut T, Shukla S, Polgar O, Macalou S, Bahr J, et al. Becatecarin (rebeccamycin analog, NSC 655649) is a transport substrate and induces expression of the ATP-binding cassette transporter, ABCG2, in lung carcinoma cells. Cancer Chemother Pharmacol. 2009;64:575-83 pubmed 出版商
Wang J, Guo L, Chen L, Zeng Y, Lu S. Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line. Cancer Res. 2007;67:3716-24 pubmed
产品信息
产品类型 :
抗体
产品名称 :
CD338 (ABCG2) Monoclonal Antibody (5D3), PE, eBioscience
目录# :
12-8888-42
规格 :
100试验
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 5 µL (0.25 µg)/test
物种 :
人类
克隆 :
5D3
抗体亚型 :
IgG2b, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
ABCG2, is also known as placenta-specific ABC transporter and breast cancer resistance protein (BCRP1). ABCG2 confers resistance for a variety of chemotherapeutic agents, including anthracyclines, mitoxantrone, bisantrene and topotecan. Under normal conditions, ABCG2 may serve a protective function by removing toxins from the cell, and plays an important role in regulating stem cell differentiation. ABCG2 is responsible for the side population (SP) phenotype and is widely expressed in a large variety of stem cells, making it an important stem cell marker. ABCG2 may have N-linked glycosylation and may dimerize in vivo. ABCG2 is abundantly expressed in placenta, liver, intestine and stem cells.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 5 µL (0.25 µg)/test
别名 :
ABC transporter; ABC15; Abcg2; ABCP; AI428558; ATP binding cassette subfamily G member 2 (Junior blood group); ATP-binding cassette sub-family G member 2; ATP-binding cassette transporter G2; ATP-binding cassette, sub-family G (WHITE), member 2; ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group); BCRP; Bcrp1; BMDP; Breast cancer resistance protein; breast cancer resistance protein 1 homolog; Broad substrate specificity ATP-binding cassette transporter ABCG2; CD338; CDw338; EST157481; GOUT1; mitoxantrone resistance protein 1; mitoxantrone resistance-associated protein; MRX; multi drug resistance efflux transport ATP-binding cassette sub-family G (WHITE) member 2; MXR; MXR1; MXR-1; placenta specific MDR protein; placenta-specific ATP-binding cassette transporter; UAQTL1; Urate exporter
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国