Phospho-mTOR (Ser2448) Monoclonal Antibody (MRRBY), PE, eBioscience

产品简要

公司名称 :

赛默飞世尔

其他品牌 :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

产品类型 :

抗体

产品名称 :

Phospho-mTOR (Ser2448) Monoclonal Antibody (MRRBY), PE, eBioscience

12-9718-41

规格 :

25试验

价格 :

美国161

克隆性 :

单克隆

宿主 :

小鼠

共轭标签 :

克隆名称 :

MRRBY

反应物种 :

人类, 小鼠

应用 :

流式细胞仪

更多信息或购买 :

赛默飞世尔产品网页

文章摘录数: 11

出版应用/物种/样本/稀释	参考文献
流式细胞仪; 小鼠; 图 2c	Alissafi T, Hatzioannou A, Mintzas K, Barouni R, Banos A, Sormendi S, et al. Autophagy orchestrates the regulatory program of tumor-associated myeloid-derived suppressor cells. J Clin Invest. 2018;128:3840-3852 pubmed 出版商
	Harder I, M xfc nchhalfen M, Andrieux G, Boerries M, Grimbacher B, Eibel H, et al. Dysregulated PI3K Signaling in B Cells of CVID Patients. Cells. 2022;11: pubmed 出版商
	Yang W, Yu T, Huang X, Bilotta A, Xu L, Lu Y, et al. Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity. Nat Commun. 2020;11:4457 pubmed 出版商
	Tan D, Li Y, Yang C, Li J, Tan S, Chin D, et al. PRMT5 Modulates Splicing for Genome Integrity and Preserves Proteostasis of Hematopoietic Stem Cells. Cell Rep. 2019;26:2316-2328.e6 pubmed 出版商
	Sohrabi Y, Lagache S, Schnack L, Godfrey R, Kahles F, Bruemmer D, et al. mTOR-Dependent Oxidative Stress Regulates oxLDL-Induced Trained Innate Immunity in Human Monocytes. Front Immunol. 2018;9:3155 pubmed 出版商
	Vaeth M, Maus M, Klein Hessling S, Freinkman E, Yang J, Eckstein M, et al. Store-Operated Ca2+ Entry Controls Clonal Expansion of T Cells through Metabolic Reprogramming. Immunity. 2017;47:664-679.e6 pubmed 出版商
	Chamoto K, Chowdhury P, Kumar A, Sonomura K, Matsuda F, Fagarasan S, et al. Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity. Proc Natl Acad Sci U S A. 2017;114:E761-E770 pubmed 出版商
	Donnelly R, Loftus R, Keating S, Liou K, Biron C, Gardiner C, et al. mTORC1-dependent metabolic reprogramming is a prerequisite for NK cell effector function. J Immunol. 2014;193:4477-84 pubmed 出版商
	Lee K, Heffington L, Jellusova J, Nam K, Raybuck A, Cho S, et al. Requirement for Rictor in homeostasis and function of mature B lymphoid cells. Blood. 2013;122:2369-79 pubmed 出版商
	Laplante M, Sabatini D. mTOR signaling in growth control and disease. Cell. 2012;149:274-93 pubmed 出版商
	Lee K, Gudapati P, Dragovic S, Spencer C, Joyce S, Killeen N, et al. Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways. Immunity. 2010;32:743-53 pubmed 出版商

产品信息

产品类型 :

抗体

产品名称 :

Phospho-mTOR (Ser2448) Monoclonal Antibody (MRRBY), PE, eBioscience

目录# :

12-9718-41

规格 :

25试验

价格 :

美国161

克隆性 :

单克隆

纯度 :

亲和色谱

宿主 :

小鼠

反应物种 :

人类, 小鼠

应用 :

Flow Cytometry: 5 µL (0.06 µg)/test

物种 :

人类, 小鼠

克隆 :

MRRBY

抗体亚型 :

IgG2a, kappa

储存 :

4° C, store in dark, DO NOT FREEZE!

描述 :

Mammalian target of rapamycin (mTOR) is a serine/threonine kinase that plays a key role in cell growth, cell proliferation, and protein synthesis. mTOR mediates phosphoinositide 3-kinase and Akt/PKB signaling, resulting in phosphorylation of 4EBP1, and initiation of mRNA translation. A second pathway involves regulation of ribosomal S6 kinase, which affects ribosome biogenesis and translation elongation. Mutations affecting the gene results in Smith-Kingsmore syndrome.

格式 :

液体

应用w/稀释 :

Flow Cytometry: 5 µL (0.06 µg)/test

别名 :

2610315D21Rik; AI327068; angiopoietin-like factor CDT6; FK506 binding protein 12-rapamycin associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; FKBP12-rapamycin complex-associated protein 1; FKBP-rapamycin associated protein; FKBP-rapamycin associated protein (FRAP); FKBP-rapamycin-associated protein FRAP; flat; FRAP; FRAP1; FRAP2; Mammalian target of rapamycin; mechanistic target of rapamycin; mechanistic target of rapamycin (serine/threonine kinase); mechanistic target of rapamycin kinase; Mtor; m-TOR; mTORC1; Raft1; Rapamycin and FKBP12 target 1; rapamycin and FKBP12 target-1 protein; rapamycin associated protein FRAP2; rapamycin target protein 1; RAPT1; serine/threonine-protein kinase mTOR; SKS

更多信息或购买 :

赛默飞世尔产品网页

公司信息

赛默飞世尔

上海浦东新金桥路27号7号楼

analyze.cn@thermofisher.com

http://www.thermo.com.cn

1084193588

公司总部: 美国