产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD281 (TLR1) Monoclonal Antibody (GD2.F4), PE, eBioscience™
目录 :
12-9911-42
规格 :
100试验
价格 :
美国381
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
PE
克隆名称 :
GD2.F4
反应物种 :
人类
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 9
参考文献
Steiner M, Hawranek T, Schneider M, Ferreira F, Horejs Hoeck J, Harrer A, et al. Elevated Toll-Like Receptor-Induced CXCL8 Secretion in Human Blood Basophils from Allergic Donors Is Independent of Toll-Like Receptor Expression Levels. PLoS ONE. 2016;11:e0149275 pubmed 出版商
Judge C, Reyes Aviles E, Conry S, Sieg S, Feng Z, Weinberg A, et al. HBD-3 induces NK cell activation, IFN-γ secretion and mDC dependent cytolytic function. Cell Immunol. 2015;297:61-8 pubmed 出版商
Conrad K, Wu P, Sieper J, Syrbe U. In vivo pre-activation of monocytes in patients with axial spondyloarthritis. Arthritis Res Ther. 2015;17:179 pubmed 出版商
Juthani Mehta M, Guo X, Shaw A, Towle V, Ning Y, Wang X, et al. Innate Immune Responses in the Neutrophils of Community Dwelling and Nursing Home Elders. J Aging Sci. 2014;2: pubmed
Novis C, Archin N, Buzon M, Verdin E, Round J, Lichterfeld M, et al. Reactivation of latent HIV-1 in central memory CD4? T cells through TLR-1/2 stimulation. Retrovirology. 2013;10:119 pubmed 出版商
Harman A, Bye C, Nasr N, Sandgren K, Kim M, Mercier S, et al. Identification of lineage relationships and novel markers of blood and skin human dendritic cells. J Immunol. 2013;190:66-79 pubmed 出版商
Funderburg N, Sieg S. Diminished responsiveness to human β-defensin-3 and decreased TLR1 expression on monocytes and mDCs from HIV-1-infected patients. J Leukoc Biol. 2012;92:1103-9 pubmed 出版商
Oberg H, Ly T, Ussat S, Meyer T, Kabelitz D, Wesch D. Differential but direct abolishment of human regulatory T cell suppressive capacity by various TLR2 ligands. J Immunol. 2010;184:4733-40 pubmed 出版商
Peiser M, Koeck J, Kirschning C, Wittig B, Wanner R. Human Langerhans cells selectively activated via Toll-like receptor 2 agonists acquire migratory and CD4+T cell stimulatory capacity. J Leukoc Biol. 2008;83:1118-27 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
CD281 (TLR1) Monoclonal Antibody (GD2.F4), PE, eBioscience™
目录# :
12-9911-42
规格 :
100试验
价格 :
美国381
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 5 µL (1 µg)/test
物种 :
人类
克隆 :
GD2.F4
抗体亚型 :
IgG1, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
TLR1 protein is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The Toll-like receptor (TLR) family in mammals are comprised of a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and an IL-1 receptor motif in the cytoplasmic domain. The TLRs could constitute an important and unrecognized component of innate immunity in humans. In mice, TLR1 interacts with TLR2 and co-expression of TLR1 and TLR2 enhance the NF-kappaB activation in response to a synthetic lipopeptide. They recognize the lipid configuration of the native mycobacterial lipoprotein as well as several tri-acylated lipopeptides. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for the TLR1 gene.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 5 µL (1 µg)/test
别名 :
CD281; KIAA0012; rsc786; TIL; TIL. LPRS5; Tlr1; toll like receptor 1; Toll/interleukin-1 receptor-like protein; toll-like receptor 1
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国