HLA-E Monoclonal Antibody (3D12HLA-E), PE, eBioscience™ | 赛默飞世尔 12-9953-42 产品信息

产品简要

公司名称 :

赛默飞世尔

其他品牌 :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

产品类型 :

抗体

产品名称 :

HLA-E Monoclonal Antibody (3D12HLA-E), PE, eBioscience™

12-9953-42

规格 :

100试验

价格 :

美国385

克隆性 :

单克隆

宿主 :

小鼠

共轭标签 :

克隆名称 :

3D12HLA-E

反应物种 :

人类

应用 :

流式细胞仪

更多信息或购买 :

赛默飞世尔产品网页

文章摘录数: 16

参考文献
Carré T, Thiery J, Janji B, Terry S, Gros G, Meurice G, et al. Selection of tumor‑resistant variants following sustained natural killer cell‑mediated immune stress. Oncol Rep. 2021;45:582-594 pubmed 出版商
Laplagne C, Meddour S, Figarol S, Michelas M, Calvayrac O, Favre G, et al. Vγ9Vδ2 T Cells Activation Through Phosphoantigens Can Be Impaired by a RHOB Rerouting in Lung Cancer. Front Immunol. 2020;11:1396 pubmed 出版商
McWilliams E, Mele J, Cheney C, Timmerman E, Fiazuddin F, Strattan E, et al. Therapeutic CD94/NKG2A blockade improves natural killer cell dysfunction in chronic lymphocytic leukemia. Oncoimmunology. 2016;5:e1226720 pubmed
Andersson E, Poschke I, Villabona L, Carlson J, Lundqvist A, Kiessling R, et al. Non-classical HLA-class I expression in serous ovarian carcinoma: Correlation with the HLA-genotype, tumor infiltrating immune cells and prognosis. Oncoimmunology. 2016;5:e1052213 pubmed
Ruggeri L, Urbani E, AndrÃ© P, Mancusi A, Tosti A, Topini F, et al. Effects of anti-NKG2A antibody administration on leukemia and normal hematopoietic cells. Haematologica. 2016;101:626-33 pubmed 出版商
Harrer A, Wipfler P, Pilz G, Oppermann K, Haschke Becher E, Afazel S, et al. Adaptive Immune Responses in a Multiple Sclerosis Patient with Acute Varicella-Zoster Virus Reactivation during Treatment with Fingolimod. Int J Mol Sci. 2015;16:21832-45 pubmed 出版商
Pasero C, Gravis G, Granjeaud S, Guerin M, Thomassin Piana J, Rocchi P, et al. Highly effective NK cells are associated with good prognosis in patients with metastatic prostate cancer. Oncotarget. 2015;6:14360-73 pubmed
SÃ¡nchez MartÃnez D, Azaceta G, Muntasell A, AguilÃ³ N, NÃºÃ±ez D, GÃ¡lvez E, et al. Human NK cells activated by EBV+ lymphoblastoid cells overcome anti-apoptotic mechanisms of drug resistance in haematological cancer cells. Oncoimmunology. 2015;4:e991613 pubmed
Braun M, BjÃ¶rkstrÃ¶m N, Gupta S, SundstrÃ¶m K, Ahlm C, KlingstrÃ¶m J, et al. NK cell activation in human hantavirus infection explained by virus-induced IL-15/IL15RÎ± expression. PLoS Pathog. 2014;10:e1004521 pubmed 出版商
Lim D, Yawata N, Selva K, Li N, Tsai C, Yeong L, et al. The combination of type I IFN, TNF-Î±, and cell surface receptor engagement with dendritic cells enables NK cells to overcome immune evasion by dengue virus. J Immunol. 2014;193:5065-75 pubmed 出版商
Rygh C, Wang J, Thuen M, Gras Navarro A, Huuse E, Thorsen F, et al. Dynamic contrast enhanced MRI detects early response to adoptive NK cellular immunotherapy targeting the NG2 proteoglycan in a rat model of glioblastoma. PLoS ONE. 2014;9:e108414 pubmed 出版商
Cheent K, Jamil K, Cassidy S, Liu M, Mbiribindi B, Mulder A, et al. Synergistic inhibition of natural killer cells by the nonsignaling molecule CD94. Proc Natl Acad Sci U S A. 2013;110:16981-6 pubmed 出版商
Sloan R, Kuhl B, Donahue D, Roland A, Bar Magen T, Wainberg M. Transcription of preintegrated HIV-1 cDNA modulates cell surface expression of major histocompatibility complex class I via Nef. J Virol. 2011;85:2828-36 pubmed 出版商
Takao S, Ishikawa T, Yamashita K, Uchiyama T. The rapid induction of HLA-E is essential for the survival of antigen-activated naive CD4 T cells from attack by NK cells. J Immunol. 2010;185:6031-40 pubmed 出版商
Wooden S, Kalb S, Cotter R, Soloski M. Cutting edge: HLA-E binds a peptide derived from the ATP-binding cassette transporter multidrug resistance-associated protein 7 and inhibits NK cell-mediated lysis. J Immunol. 2005;175:1383-7 pubmed
Strong R, Holmes M, Li P, Braun L, Lee N, Geraghty D. HLA-E allelic variants. Correlating differential expression, peptide affinities, crystal structures, and thermal stabilities. J Biol Chem. 2003;278:5082-90 pubmed

产品信息

产品类型 :

抗体

产品名称 :

HLA-E Monoclonal Antibody (3D12HLA-E), PE, eBioscience™

目录# :

12-9953-42

规格 :

100试验

价格 :

美国385

克隆性 :

单克隆

纯度 :

亲和色谱

宿主 :

小鼠

反应物种 :

人类

应用 :

Flow Cytometry: 5 µL (0.5 µg)/test

物种 :

人类

克隆 :

3D12HLA-E

抗体亚型 :

IgG1, kappa

储存 :

4° C, store in dark, DO NOT FREEZE!

描述 :

HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.

格式 :

液体

应用w/稀释 :

Flow Cytometry: 5 µL (0.5 µg)/test

别名 :

DAMA-277I14.1; DAQB-90C11.16; DKFZp686P19218; EA1.2; EA2.1; FLJ26655; HLA class I histocompatibility antigen, alpha chain E; HLA class I histocompatibility antigen, E alpha chain; HLA-6.2; HLAE; HLA-E; lymphocyte antigen; major histocompatibility complex, class I, E; MHC; MHC 1; MHC class I antigen E; MHC HLA-E alpha-1; MHC HLA-E alpha-2.1; MHC1; QA1; sHLA-E; Soluble HLA class I histocompatibility antigen, alpha chain E

更多信息或购买 :

赛默飞世尔产品网页

公司信息

赛默飞世尔

上海浦东新金桥路27号7号楼

analyze.cn@thermofisher.com

http://www.thermo.com.cn

1084193588

公司总部: 美国