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豚鼠, 人类, 小鼠, 大鼠,
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免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片
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文章摘录数: 163
  • 免疫组化-冰冻切片; 小鼠; 1:50; 图 6h
Morse S, Boltersdorf T, Harriss B, Chan T, Baxan N, Jung H, et al. Neuron labeling with rhodamine-conjugated Gd-based MRI contrast agents delivered to the brain via focused ultrasound. Theranostics. 2020;10:2659-2674 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:500-1:1000; 图 4i, 4j, s4b
Wall C, Rose C, Adrian M, Zeng Y, Kirkpatrick D, Bingol B. PPEF2 Opposes PINK1-Mediated Mitochondrial Quality Control by Dephosphorylating Ubiquitin. Cell Rep. 2019;29:3280-3292.e7 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:100; 图 s4b
Ising C, Venegas C, Zhang S, Scheiblich H, Schmidt S, Vieira Saecker A, et al. NLRP3 inflammasome activation drives tau pathology. Nature. 2019;: pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 1a
Blomfield I, Rocamonde B, Masdeu M, Mulugeta E, Vaga S, van den Berg D, et al. Id4 promotes the elimination of the pro-activation factor Ascl1 to maintain quiescence of adult hippocampal stem cells. elife. 2019;8: pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 1:1000; 图 e5b
Schirmer L, Velmeshev D, Holmqvist S, Kaufmann M, Werneburg S, Jung D, et al. Neuronal vulnerability and multilineage diversity in multiple sclerosis. Nature. 2019;573:75-82 pubmed 出版商
  • 免疫组化; 小鼠; 图 2a
Joy M, Ben Assayag E, Shabashov Stone D, Liraz Zaltsman S, Mazzitelli J, Arenas M, et al. CCR5 Is a Therapeutic Target for Recovery after Stroke and Traumatic Brain Injury. Cell. 2019;176:1143-1157.e13 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 2d
Betlazar C, Harrison Brown M, Middleton R, Banati R, Liu G. Cellular Sources and Regional Variations in the Expression of the Neuroinflammatory Marker Translocator Protein (TSPO) in the Normal Brain. Int J Mol Sci. 2018;19: pubmed 出版商
  • 免疫组化; 小鼠; 图 1c
  • 免疫印迹; 小鼠; 图 1d
Sato J, Horibe S, Kawauchi S, Sasaki N, Hirata K, Rikitake Y. Involvement of aquaporin-4 in laminin-enhanced process formation of mouse astrocytes in 2D culture: Roles of dystroglycan and α-syntrophin in aquaporin-4 expression. J Neurochem. 2018;147:495-513 pubmed 出版商
  • 免疫组化; 小鼠; 图 1d
Zhao C, Dong C, Frah M, Deng Y, Marie C, Zhang F, et al. Dual Requirement of CHD8 for Chromatin Landscape Establishment and Histone Methyltransferase Recruitment to Promote CNS Myelination and Repair. Dev Cell. 2018;45:753-768.e8 pubmed 出版商
  • 免疫组化; 人类; 1:250; 图 1a
  • 免疫组化; 小鼠; 1:1000; 图 1c
Reichenbach N, Delekate A, Breithausen B, Keppler K, Poll S, Schulte T, et al. P2Y1 receptor blockade normalizes network dysfunction and cognition in an Alzheimer's disease model. J Exp Med. 2018;215:1649-1663 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 4a, 5c
Zukor K, Wang H, Siddharthan V, Julander J, Morrey J. Zika virus-induced acute myelitis and motor deficits in adult interferon ??/? receptor knockout mice. J Neurovirol. 2018;24:273-290 pubmed 出版商
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Yungher B, Ribeiro M, Park K. Regenerative Responses and Axon Pathfinding of Retinal Ganglion Cells in Chronically Injured Mice. Invest Ophthalmol Vis Sci. 2017;58:1743-1750 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:1000; 图 12a
Zhu Y, Lyapichev K, Lee D, Motti D, Ferraro N, Zhang Y, et al. Macrophage Transcriptional Profile Identifies Lipid Catabolic Pathways That Can Be Therapeutically Targeted after Spinal Cord Injury. J Neurosci. 2017;37:2362-2376 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 1f
Liddelow S, Guttenplan K, Clarke L, Bennett F, Bohlen C, Schirmer L, et al. Neurotoxic reactive astrocytes are induced by activated microglia. Nature. 2017;541:481-487 pubmed 出版商
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Behm M, Wahlstedt H, Widmark A, Eriksson M, Ohman M. Accumulation of nuclear ADAR2 regulates adenosine-to-inosine RNA editing during neuronal development. J Cell Sci. 2017;130:745-753 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:1000; 图 3
Kim J, Lee J, Sun W. Isolation and Culture of Adult Neural Stem Cells from the Mouse Subcallosal Zone. J Vis Exp. 2016;: pubmed 出版商
  • 免疫组化; 小鼠; 图 8m
Ji B, Kaneko H, Minamimoto T, Inoue H, Takeuchi H, Kumata K, et al. Multimodal Imaging for DREADD-Expressing Neurons in Living Brain and Their Application to Implantation of iPSC-Derived Neural Progenitors. J Neurosci. 2016;36:11544-11558 pubmed
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 6d
Song D, Wilson B, Zhao L, Bhuyan R, Bandyopadhyay M, Lyubarsky A, et al. Retinal Pre-Conditioning by CD59a Knockout Protects against Light-Induced Photoreceptor Degeneration. PLoS ONE. 2016;11:e0166348 pubmed 出版商
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Mildner A, Huang H, Radke J, Stenzel W, Priller J. P2Y12 receptor is expressed on human microglia under physiological conditions throughout development and is sensitive to neuroinflammatory diseases. Glia. 2017;65:375-387 pubmed 出版商
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Menzel L, Kleber L, Friedrich C, Hummel R, Dangel L, Winter J, et al. Progranulin protects against exaggerated axonal injury and astrogliosis following traumatic brain injury. Glia. 2017;65:278-292 pubmed 出版商
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Zukor K, Wang H, Hurst B, Siddharthan V, van Wettere A, Pilowsky P, et al. Phrenic nerve deficits and neurological immunopathology associated with acute West Nile virus infection in mice and hamsters. J Neurovirol. 2017;23:186-204 pubmed 出版商
  • 免疫组化; 小鼠; 1:5000; 图 5a
Koyanagi S, Kusunose N, Taniguchi M, Akamine T, Kanado Y, Ozono Y, et al. Glucocorticoid regulation of ATP release from spinal astrocytes underlies diurnal exacerbation of neuropathic mechanical allodynia. Nat Commun. 2016;7:13102 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1g
Zhang L, Hua Q, Tang K, Shi C, Xie X, Zhang R. CXCR4 activation promotes differentiation of human embryonic stem cells to neural stem cells. Neuroscience. 2016;337:88-97 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:1000; 图 5a
Barron A, Tokunaga M, Zhang M, Ji B, Suhara T, Higuchi M. Assessment of neuroinflammation in a mouse model of obesity and β-amyloidosis using PET. J Neuroinflammation. 2016;13:221 pubmed 出版商
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Hillis J, Davies J, Mundim M, Al Dalahmah O, Szele F. Cuprizone demyelination induces a unique inflammatory response in the subventricular zone. J Neuroinflammation. 2016;13:190 pubmed 出版商
  • 免疫组化; 小鼠; 图 7b
Badea A, Kane L, Anderson R, Qi Y, Foster M, Cofer G, et al. The fornix provides multiple biomarkers to characterize circuit disruption in a mouse model of Alzheimer's disease. Neuroimage. 2016;142:498-511 pubmed 出版商
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Saggu R, Schumacher T, Gerich F, Rakers C, Tai K, Delekate A, et al. Astroglial NF-kB contributes to white matter damage and cognitive impairment in a mouse model of vascular dementia. Acta Neuropathol Commun. 2016;4:76 pubmed 出版商
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Urbán N, van den Berg D, Forget A, Andersen J, Demmers J, Hunt C, et al. Return to quiescence of mouse neural stem cells by degradation of a proactivation protein. Science. 2016;353:292-5 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 3a
Walker W, Oehler A, Edinger A, Wagner K, Gunn T. Oligodendroglial deletion of ESCRT-I component TSG101 causes spongiform encephalopathy. Biol Cell. 2016;108:324-337 pubmed 出版商
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Park K, Luo X, Mooney S, Yungher B, Belin S, Wang C, et al. Retinal ganglion cell survival and axon regeneration after optic nerve injury in naked mole-rats. J Comp Neurol. 2017;525:380-388 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 s2
Vasek M, Garber C, Dorsey D, Durrant D, Bollman B, Soung A, et al. A complement-microglial axis drives synapse loss during virus-induced memory impairment. Nature. 2016;534:538-43 pubmed 出版商
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Kizuka Y, Nakano M, Miura Y, Taniguchi N. Epigenetic regulation of neural N-glycomics. Proteomics. 2016;16:2854-2863 pubmed 出版商
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Funk L, Hackett A, Bunge M, Lee J. Tumor necrosis factor superfamily member APRIL contributes to fibrotic scar formation after spinal cord injury. J Neuroinflammation. 2016;13:87 pubmed 出版商
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Smeester B, O Brien E, Michlitsch K, Lee J, Beitz A. The relationship of bone-tumor-induced spinal cord astrocyte activation and aromatase expression to mechanical hyperalgesia and cold hypersensitivity in intact female and ovariectomized mice. Neuroscience. 2016;324:344-54 pubmed 出版商
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Hackett A, Lee D, Dawood A, Rodriguez M, Funk L, Tsoulfas P, et al. STAT3 and SOCS3 regulate NG2 cell proliferation and differentiation after contusive spinal cord injury. Neurobiol Dis. 2016;89:10-22 pubmed 出版商
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Hristova M, Rocha Ferreira E, Fontana X, Thei L, Buckle R, Christou M, et al. Inhibition of Signal Transducer and Activator of Transcription 3 (STAT3) reduces neonatal hypoxic-ischaemic brain damage. J Neurochem. 2016;136:981-94 pubmed 出版商
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Wang S, Hsu J, Ko C, Chiu N, Kan W, Lai M, et al. Astrocytic CCAAT/Enhancer-Binding Protein Delta Contributes to Glial Scar Formation and Impairs Functional Recovery After Spinal Cord Injury. Mol Neurobiol. 2016;53:5912-5927 pubmed 出版商
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Kizuka Y, Nakano M, Kitazume S, Saito T, Saido T, Taniguchi N. Bisecting GlcNAc modification stabilizes BACE1 protein under oxidative stress conditions. Biochem J. 2016;473:21-30 pubmed 出版商
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Fredriksson L, Stevenson T, Su E, Ragsdale M, Moore S, Craciun S, et al. Identification of a neurovascular signaling pathway regulating seizures in mice. Ann Clin Transl Neurol. 2015;2:722-38 pubmed 出版商
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Chen Y, Huang W, Séjourné J, Clipperton Allen A, Page D. Pten Mutations Alter Brain Growth Trajectory and Allocation of Cell Types through Elevated β-Catenin Signaling. J Neurosci. 2015;35:10252-67 pubmed 出版商
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Puntambekar S, Hinton D, Yin X, Savarin C, Bergmann C, Trapp B, et al. Interleukin-10 is a critical regulator of white matter lesion containment following viral induced demyelination. Glia. 2015;63:2106-2120 pubmed 出版商
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Schachtrup C, Ryu J, Mammadzada K, Khan A, Carlton P, Perez A, et al. Nuclear pore complex remodeling by p75(NTR) cleavage controls TGF-β signaling and astrocyte functions. Nat Neurosci. 2015;18:1077-80 pubmed 出版商
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O Brien E, Smeester B, Michlitsch K, Lee J, Beitz A. Colocalization of aromatase in spinal cord astrocytes: differences in expression and relationship to mechanical and thermal hyperalgesia in murine models of a painful and a non-painful bone tumor. Neuroscience. 2015;301:235-45 pubmed 出版商
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Shin C, Grossmann A, Holmen S, Robinson J. The BRAF kinase domain promotes the development of gliomas in vivo. Genes Cancer. 2015;6:9-18 pubmed
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Crouch E, Liu C, Silva Vargas V, Doetsch F. Regional and stage-specific effects of prospectively purified vascular cells on the adult V-SVZ neural stem cell lineage. J Neurosci. 2015;35:4528-39 pubmed 出版商
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Chen Roetling J, Song W, Schipper H, Regan C, Regan R. Astrocyte overexpression of heme oxygenase-1 improves outcome after intracerebral hemorrhage. Stroke. 2015;46:1093-8 pubmed 出版商
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Cantoni C, Bollman B, Licastro D, Xie M, Mikesell R, Schmidt R, et al. TREM2 regulates microglial cell activation in response to demyelination in vivo. Acta Neuropathol. 2015;129:429-47 pubmed 出版商
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Kizuka Y, Kitazume S, Fujinawa R, Saito T, Iwata N, Saido T, et al. An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease. EMBO Mol Med. 2015;7:175-89 pubmed 出版商
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Zhu Y, Soderblom C, Trojanowsky M, Lee D, Lee J. Fibronectin Matrix Assembly after Spinal Cord Injury. J Neurotrauma. 2015;32:1158-67 pubmed 出版商
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Zhu Y, Soderblom C, Krishnan V, Ashbaugh J, Bethea J, Lee J. Hematogenous macrophage depletion reduces the fibrotic scar and increases axonal growth after spinal cord injury. Neurobiol Dis. 2015;74:114-25 pubmed 出版商
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Wu C, Hung T, Chen C, Ke C, Lee C, Wang P, et al. Post-injury treatment with 7,8-dihydroxyflavone, a TrkB receptor agonist, protects against experimental traumatic brain injury via PI3K/Akt signaling. PLoS ONE. 2014;9:e113397 pubmed 出版商
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Kawase S, Kuwako K, Imai T, Renault Mihara F, Yaguchi K, Itohara S, et al. Regulatory factor X transcription factors control Musashi1 transcription in mouse neural stem/progenitor cells. Stem Cells Dev. 2014;23:2250-61 pubmed 出版商
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Howerton A, Roland A, Bale T. Dorsal raphe neuroinflammation promotes dramatic behavioral stress dysregulation. J Neurosci. 2014;34:7113-23 pubmed 出版商
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  • 免疫印迹; 小鼠
Wakatsuki S, Araki T, Sehara Fujisawa A. Neuregulin-1/glial growth factor stimulates Schwann cell migration by inducing ?5 ?1 integrin-ErbB2-focal adhesion kinase complex formation. Genes Cells. 2014;19:66-77 pubmed 出版商
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Cops E, Sashindranath M, Daglas M, Short K, da Fonseca Pereira C, Pang T, et al. Tissue-type plasminogen activator is an extracellular mediator of Purkinje cell damage and altered gait. Exp Neurol. 2013;249:8-19 pubmed 出版商
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Karasinska J, de Haan W, Franciosi S, Ruddle P, Fan J, Kruit J, et al. ABCA1 influences neuroinflammation and neuronal death. Neurobiol Dis. 2013;54:445-55 pubmed 出版商
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Phares T, Stohlman S, Hinton D, Bergmann C. Astrocyte-derived CXCL10 drives accumulation of antibody-secreting cells in the central nervous system during viral encephalomyelitis. J Virol. 2013;87:3382-92 pubmed 出版商
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Chen S, Tsai H, Hung T, Chen C, Lee C, Wu C, et al. Salidroside improves behavioral and histological outcomes and reduces apoptosis via PI3K/Akt signaling after experimental traumatic brain injury. PLoS ONE. 2012;7:e45763 pubmed 出版商
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Gerber A, Bale T. Antiinflammatory treatment ameliorates HPA stress axis dysfunction in a mouse model of stress sensitivity. Endocrinology. 2012;153:4830-7 pubmed
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Dixon K, Munro K, Boyd A, Bartlett P, Turnley A. Partial change in EphA4 knockout mouse phenotype: loss of diminished GFAP upregulation following spinal cord injury. Neurosci Lett. 2012;525:66-71 pubmed 出版商
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Skjolding A, Holst A, Broholm H, Laursen H, Juhler M. Differences in distribution and regulation of astrocytic aquaporin-4 in human and rat hydrocephalic brain. Neuropathol Appl Neurobiol. 2013;39:179-91 pubmed 出版商
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Lutz S, Raine C, Brosnan C. Loss of astrocyte connexins 43 and 30 does not significantly alter susceptibility or severity of acute experimental autoimmune encephalomyelitis in mice. J Neuroimmunol. 2012;245:8-14 pubmed 出版商
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Lewitus D, Landers J, Branch J, Smith K, Callegari G, Kohn J, et al. Biohybrid Carbon Nanotube/Agarose Fibers for Neural Tissue Engineering. Adv Funct Mater. 2011;21:2624-2632 pubmed
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Zhao L, Ma W, Fariss R, Wong W. Minocycline attenuates photoreceptor degeneration in a mouse model of subretinal hemorrhage microglial: inhibition as a potential therapeutic strategy. Am J Pathol. 2011;179:1265-77 pubmed 出版商
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Lewitus D, Smith K, Shain W, Bolikal D, Kohn J. The fate of ultrafast degrading polymeric implants in the brain. Biomaterials. 2011;32:5543-50 pubmed 出版商
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Chang C, Chen S, Lee T, Lee H, Chen S, Shyue S. Caveolin-1 deletion reduces early brain injury after experimental intracerebral hemorrhage. Am J Pathol. 2011;178:1749-61 pubmed 出版商
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Lewitus D, Smith K, Shain W, Kohn J. Ultrafast resorbing polymers for use as carriers for cortical neural probes. Acta Biomater. 2011;7:2483-91 pubmed 出版商
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Phares T, Marques C, Stohlman S, Hinton D, Bergmann C. Factors supporting intrathecal humoral responses following viral encephalomyelitis. J Virol. 2011;85:2589-98 pubmed 出版商
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Yang H, Zhuo J, Chu J, Chinnici C, Pratico D. Amelioration of the Alzheimer's disease phenotype by absence of 12/15-lipoxygenase. Biol Psychiatry. 2010;68:922-9 pubmed 出版商
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DellaValle B, Hempel C, Kurtzhals J, Penkowa M. In vivo expression of neuroglobin in reactive astrocytes during neuropathology in murine models of traumatic brain injury, cerebral malaria, and autoimmune encephalitis. Glia. 2010;58:1220-7 pubmed 出版商
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Pang J, Gao F, Wu S. Light responses and morphology of bNOS-immunoreactive neurons in the mouse retina. J Comp Neurol. 2010;518:2456-74 pubmed 出版商
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VanBrocklin M, Robinson J, Lastwika K, Khoury J, Holmen S. Targeted delivery of NRASQ61R and Cre-recombinase to post-natal melanocytes induces melanoma in Ink4a/Arflox/lox mice. Pigment Cell Melanoma Res. 2010;23:531-41 pubmed 出版商
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Ji B, Maeda J, Sawada M, Ono M, Okauchi T, Inaji M, et al. Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologies. J Neurosci. 2008;28:12255-67 pubmed 出版商
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Hoff S, Zeller F, Von Weyhern C, Wegner M, Schemann M, Michel K, et al. Quantitative assessment of glial cells in the human and guinea pig enteric nervous system with an anti-Sox8/9/10 antibody. J Comp Neurol. 2008;509:356-71 pubmed 出版商
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Blakqori G, Delhaye S, Habjan M, Blair C, S nchez Vargas I, Olson K, et al. La Crosse bunyavirus nonstructural protein NSs serves to suppress the type I interferon system of mammalian hosts. J Virol. 2007;81:4991-9 pubmed 出版商
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Herber D, Maloney J, Roth L, Freeman M, Morgan D, Gordon M. Diverse microglial responses after intrahippocampal administration of lipopolysaccharide. Glia. 2006;53:382-91 pubmed
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Wicher G, Larsson M, Rask L, Aldskogius H. Low-density lipoprotein receptor-related protein (LRP)-2/megalin is transiently expressed in a subpopulation of neural progenitors in the embryonic mouse spinal cord. J Comp Neurol. 2005;492:123-31 pubmed
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Herber D, Roth L, Wilson D, Wilson N, Mason J, Morgan D, et al. Time-dependent reduction in Abeta levels after intracranial LPS administration in APP transgenic mice. Exp Neurol. 2004;190:245-53 pubmed
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Apicelli A, Uhlmann E, Baldwin R, Ding H, Nagy A, Guha A, et al. Role of the Rap1 GTPase in astrocyte growth regulation. Glia. 2003;42:225-34 pubmed
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产品类型 :
产品名称 :
目录# :
规格 :
价格 :
克隆性 :
纯度 :
宿主 :
反应物种 :
牛, 人类, 小鼠, 大鼠
应用 :
ELISA: 0.1-0.5 µg/mL, Flow Cytometry: Assay Dependent, Immunocytochemistry: Assay Dependent, Immunofluorescence: Assay Dependent, Immunohistochemistry: 10-50 µg/mL, Immunoprecipitation: 2-5 µg, Western Blot: Assay Dependent
物种 :
牛, 人类, 小鼠, 大鼠
克隆 :
抗体亚型 :
IgG2a, kappa
储存 :
描述 :
GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family. GFAP is heavily and specifically expressed in astrocytes and certain astroglia of the central nervous system, in satellite cells of peripheral ganglia, and in non-myelinating Schwann cells of peripheral nerves. In addition, neural stem cells strongly express GFAP. Antibodies to GFAP are very useful as markers of astrocytic cells. In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. GFAP is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms.
免疫原 :
Enriched bovine glial filaments.
格式 :
应用w/稀释 :
ELISA: 0.1-0.5 µg/mL, Flow Cytometry: Assay Dependent, Immunocytochemistry: Assay Dependent, Immunofluorescence: Assay Dependent, Immunohistochemistry: 10-50 µg/mL, Immunoprecipitation: 2-5 µg, Western Blot: Assay Dependent
别名 :
AI836096; ALXDRD; cb345; class III intermediate filament protein; etID36982.3; FLJ45472; gfap; GFAP epsilon; gfap protein; gfapl; Glial fibrillary acidic protein; glial fibrillary acidic protein alpha; I79_011607; intermediate filament; intermediate filament protein; intermediate filament protein; GFAP; Unknown (protein for MGC:139638); wu:fb34h11; wu:fk42c12; xx:af506734; zgc:110485; zGFAP; intermediate filament protein; zrf-1 antigen
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公司总部: 美国