产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD115 (c-fms) Monoclonal Antibody (AFS98), Biotin, eBioscience™
目录 :
13-1152-85
规格 :
500微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
生物素
克隆名称 :
AFS98
反应物种 :
小鼠
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 113
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 1:10; 图 s3a
Kobayakawa K, Ohkawa Y, Yoshizaki S, Tamaru T, Saito T, Kijima K, et al. Macrophage centripetal migration drives spontaneous healing process after spinal cord injury. Sci Adv. 2019;5:eaav5086 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 1a
Hoving L, De Vries M, de Jong R, Katiraei S, Pronk A, Quax P, et al. The Prebiotic Inulin Aggravates Accelerated Atherosclerosis in Hypercholesterolemic APOE*3-Leiden Mice. Nutrients. 2018;10: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s4
Koronyo Y, Salumbides B, Sheyn J, Pelissier L, Li S, Ljubimov V, et al. Therapeutic effects of glatiramer acetate and grafted CD115⁺ monocytes in a mouse model of Alzheimer's disease. Brain. 2015;138:2399-422 pubmed 出版商
Jin X, Liu L, Zhang Y, Xiang Y, Yin G, Lu Y, et al. Advanced Glycation End Products Enhance Murine Monocyte Proliferation in Bone Marrow and Prime Them into an Inflammatory Phenotype through MAPK Signaling. J Diabetes Res. 2018;2018:2527406 pubmed 出版商
Tsantikos E, Lau M, Castelino C, Maxwell M, Passey S, Hansen M, et al. Granulocyte-CSF links destructive inflammation and comorbidities in obstructive lung disease. J Clin Invest. 2018;128:2406-2418 pubmed 出版商
Liron T, Raphael B, Hiram Bab S, Bab I, Gabet Y. Bone loss in C57BL/6J-OlaHsd mice, a substrain of C57BL/6J carrying mutated alpha-synuclein and multimerin-1 genes. J Cell Physiol. 2018;233:371-377 pubmed 出版商
Khedoe P, de Kleijn S, van Oeveren Rietdijk A, Plomp J, de Boer H, van Pel M, et al. Acute and chronic effects of treatment with mesenchymal stromal cells on LPS-induced pulmonary inflammation, emphysema and atherosclerosis development. PLoS ONE. 2017;12:e0183741 pubmed 出版商
Gilboa D, Haim Ohana Y, Deshet Unger N, Ben Califa N, Hiram Bab S, Reuveni D, et al. Erythropoietin enhances Kupffer cell number and activity in the challenged liver. Sci Rep. 2017;7:10379 pubmed 出版商
Hänggi K, Vasilikos L, Valls A, Yerbes R, Knop J, Spilgies L, et al. RIPK1/RIPK3 promotes vascular permeability to allow tumor cell extravasation independent of its necroptotic function. Cell Death Dis. 2017;8:e2588 pubmed 出版商
Al Sadoun H, Burgess M, Hentges K, Mace K. Enforced Expression of Hoxa3 Inhibits Classical and Promotes Alternative Activation of Macrophages In Vitro and In Vivo. J Immunol. 2016;197:872-84 pubmed 出版商
Pietras E, Mirantes Barbeito C, Fong S, Loeffler D, Kovtonyuk L, Zhang S, et al. Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal. Nat Cell Biol. 2016;18:607-18 pubmed 出版商
Wang T, Wang Z, Yang P, Xia L, Zhou M, Wang S, et al. PER1 prevents excessive innate immune response during endotoxin-induced liver injury through regulation of macrophage recruitment in mice. Cell Death Dis. 2016;7:e2176 pubmed 出版商
Zondler L, Müller K, Khalaji S, Bliederhäuser C, Ruf W, Grozdanov V, et al. Peripheral monocytes are functionally altered and invade the CNS in ALS patients. Acta Neuropathol. 2016;132:391-411 pubmed 出版商
Choudhary S, Goetjen A, Estus T, Jacome Galarza C, Aguila H, Lorenzo J, et al. Serum Amyloid A3 Secreted by Preosteoclasts Inhibits Parathyroid Hormone-stimulated cAMP Signaling in Murine Osteoblasts. J Biol Chem. 2016;291:3882-94 pubmed 出版商
Schippers A, Muschaweck M, Clahsen T, Tautorat S, Grieb L, Tenbrock K, et al. β7-Integrin exacerbates experimental DSS-induced colitis in mice by directing inflammatory monocytes into the colon. Mucosal Immunol. 2016;9:527-38 pubmed 出版商
Hope C, Ollar S, Heninger E, Hebron E, Jensen J, Kim J, et al. TPL2 kinase regulates the inflammatory milieu of the myeloma niche. Blood. 2014;123:3305-15 pubmed 出版商
Petvises S, O Neill H. Distinct progenitor origin distinguishes a lineage of dendritic-like cells in spleen. Front Immunol. 2014;4:501 pubmed 出版商
Williams T, Wise A, Alikhan M, Layton D, Ricardo S. Establishing the flow cytometric assessment of myeloid cells in kidney ischemia/reperfusion injury. Cytometry A. 2014;85:256-67 pubmed 出版商
Lionakis M, Swamydas M, Fischer B, Plantinga T, Johnson M, Jaeger M, et al. CX3CR1-dependent renal macrophage survival promotes Candida control and host survival. J Clin Invest. 2013;123:5035-51 pubmed 出版商
Song K, Herzog B, Sheng M, Fu J, McDaniel J, Chen H, et al. Lenalidomide inhibits lymphangiogenesis in preclinical models of mantle cell lymphoma. Cancer Res. 2013;73:7254-64 pubmed 出版商
Maina V, Marrella V, Mantero S, Cassani B, Fontana E, Anselmo A, et al. Hypomorphic mutation in the RAG2 gene affects dendritic cell distribution and migration. J Leukoc Biol. 2013;94:1221-30 pubmed 出版商
Yamane F, Nishikawa Y, Matsui K, Asakura M, Iwasaki E, Watanabe K, et al. CSF-1 receptor-mediated differentiation of a new type of monocytic cell with B cell-stimulating activity: its selective dependence on IL-34. J Leukoc Biol. 2014;95:19-31 pubmed 出版商
Noonan T, Lukas S, Peet G, Pelletier J, Panzenbeck M, Hanidu A, et al. The oxidase activity of vascular adhesion protein-1 (VAP-1) is essential for function. Am J Clin Exp Immunol. 2013;2:172-85 pubmed
Garcia J, Pino P, Mizutani M, Cardona S, Charo I, Ransohoff R, et al. Regulation of adaptive immunity by the fractalkine receptor during autoimmune inflammation. J Immunol. 2013;191:1063-72 pubmed 出版商
Fujieda Y, Manno A, Hayashi Y, Rhodes N, Guo L, Arita M, et al. Inflammation and resolution are associated with upregulation of fatty acid ?-oxidation in Zymosan-induced peritonitis. PLoS ONE. 2013;8:e66270 pubmed 出版商
Zhu M, Van Dyke T, Gyurko R. Resolvin E1 regulates osteoclast fusion via DC-STAMP and NFATc1. FASEB J. 2013;27:3344-53 pubmed 出版商
Liu Z, Petersen R, DEVIREDDY L. Impaired neutrophil function in 24p3 null mice contributes to enhanced susceptibility to bacterial infections. J Immunol. 2013;190:4692-706 pubmed 出版商
Debien E, Mayol K, Biajoux V, Daussy C, De Aguero M, Taillardet M, et al. S1PR5 is pivotal for the homeostasis of patrolling monocytes. Eur J Immunol. 2013;43:1667-75 pubmed 出版商
Helmersson S, Sundstedt A, Deronic A, Leanderson T, Ivars F. Amelioration of experimental autoimmune encephalomyelitis by the quinoline-3-carboxamide paquinimod: reduced priming of proinflammatory effector CD4(+) T cells. Am J Pathol. 2013;182:1671-80 pubmed 出版商
McMahan R, Wang X, Cheng L, Krisko T, Smith M, El Kasmi K, et al. Bile acid receptor activation modulates hepatic monocyte activity and improves nonalcoholic fatty liver disease. J Biol Chem. 2013;288:11761-70 pubmed 出版商
Soehnlein O, Drechsler M, Döring Y, Lievens D, Hartwig H, Kemmerich K, et al. Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes. EMBO Mol Med. 2013;5:471-81 pubmed 出版商
Zhang Y, Yang P, Sun T, Li D, Xu X, Rui Y, et al. miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis. Nat Cell Biol. 2013;15:284-94 pubmed 出版商
Zinkernagel M, Chinnery H, Ong M, Petitjean C, Voigt V, McLenachan S, et al. Interferon ?-dependent migration of microglial cells in the retina after systemic cytomegalovirus infection. Am J Pathol. 2013;182:875-85 pubmed 出版商
Helk E, Bernin H, Ernst T, Ittrich H, Jacobs T, Heeren J, et al. TNF?-mediated liver destruction by Kupffer cells and Ly6Chi monocytes during Entamoeba histolytica infection. PLoS Pathog. 2013;9:e1003096 pubmed 出版商
Chao L, Soto E, Hong C, Ito A, Pei L, Chawla A, et al. Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice. J Lipid Res. 2013;54:806-15 pubmed 出版商
Binder N, Puchner A, Niederreiter B, Hayer S, Leiss H, Blüml S, et al. Tumor necrosis factor-inhibiting therapy preferentially targets bone destruction but not synovial inflammation in a tumor necrosis factor-driven model of rheumatoid arthritis. Arthritis Rheum. 2013;65:608-17 pubmed 出版商
Hoshino A, Ueha S, Hanada S, Imai T, Ito M, Yamamoto K, et al. Roles of chemokine receptor CX3CR1 in maintaining murine bone homeostasis through the regulation of both osteoblasts and osteoclasts. J Cell Sci. 2013;126:1032-45 pubmed 出版商
Duwaerts C, Gehring S, Cheng C, Van Rooijen N, Gregory S. Contrasting responses of Kupffer cells and inflammatory mononuclear phagocytes to biliary obstruction in a mouse model of cholestatic liver injury. Liver Int. 2013;33:255-65 pubmed 出版商
Ren D, Wang X, Ha T, Liu L, Kalbfleisch J, Gao X, et al. SR-A deficiency reduces myocardial ischemia/reperfusion injury; involvement of increased microRNA-125b expression in macrophages. Biochim Biophys Acta. 2013;1832:336-46 pubmed 出版商
Charles J, Hsu L, Niemi E, Weiss A, Aliprantis A, Nakamura M. Inflammatory arthritis increases mouse osteoclast precursors with myeloid suppressor function. J Clin Invest. 2012;122:4592-605 pubmed 出版商
Hamilton J, Lacey D, Turner A, De Kok B, Huynh J, Scholz G. Hypoxia enhances the proliferative response of macrophages to CSF-1 and their pro-survival response to TNF. PLoS ONE. 2012;7:e45853 pubmed 出版商
Pello O, Chevre R, Laoui D, De Juan A, Lolo F, Andrés Manzano M, et al. In vivo inhibition of c-MYC in myeloid cells impairs tumor-associated macrophage maturation and pro-tumoral activities. PLoS ONE. 2012;7:e45399 pubmed 出版商
Haka A, Potteaux S, Fraser H, Randolph G, Maxfield F. Quantitative analysis of monocyte subpopulations in murine atherosclerotic plaques by multiphoton microscopy. PLoS ONE. 2012;7:e44823 pubmed
Serafini N, Dahdah A, Barbet G, Demion M, Attout T, Gautier G, et al. The TRPM4 channel controls monocyte and macrophage, but not neutrophil, function for survival in sepsis. J Immunol. 2012;189:3689-99 pubmed
He H, Xu J, Warren C, Duan D, Li X, Wu L, et al. Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages. Blood. 2012;120:3152-62 pubmed 出版商
Virtuoso L, Harden J, Sotomayor P, Sigurdson W, Yoshimura F, Egilmez N, et al. Characterization of iNOS(+) Neutrophil-like ring cell in tumor-bearing mice. J Transl Med. 2012;10:152 pubmed 出版商
Fromm P, Kling J, Mack M, Sedgwick J, Korner H. Loss of TNF signaling facilitates the development of a novel Ly-6C(low) macrophage population permissive for Leishmania major infection. J Immunol. 2012;188:6258-66 pubmed 出版商
Huynh J, Kwa M, Cook A, Hamilton J, Scholz G. CSF-1 receptor signalling from endosomes mediates the sustained activation of Erk1/2 and Akt in macrophages. Cell Signal. 2012;24:1753-61 pubmed 出版商
Diao J, Mikhailova A, Tang M, Gu H, Zhao J, Cattral M. Immunostimulatory conventional dendritic cells evolve into regulatory macrophage-like cells. Blood. 2012;119:4919-27 pubmed 出版商
Arai A, Mizoguchi T, Harada S, Kobayashi Y, Nakamichi Y, Yasuda H, et al. Fos plays an essential role in the upregulation of RANK expression in osteoclast precursors within the bone microenvironment. J Cell Sci. 2012;125:2910-7 pubmed 出版商
Meda C, Molla F, De Pizzol M, Regano D, Maione F, Capano S, et al. Semaphorin 4A exerts a proangiogenic effect by enhancing vascular endothelial growth factor-A expression in macrophages. J Immunol. 2012;188:4081-92 pubmed 出版商
Rose S, Misharin A, Perlman H. A novel Ly6C/Ly6G-based strategy to analyze the mouse splenic myeloid compartment. Cytometry A. 2012;81:343-50 pubmed 出版商
de Bruin A, Libregts S, Valkhof M, Boon L, Touw I, Nolte M. IFN? induces monopoiesis and inhibits neutrophil development during inflammation. Blood. 2012;119:1543-54 pubmed 出版商
Vaknin I, Kunis G, Miller O, Butovsky O, Bukshpan S, Beers D, et al. Excess circulating alternatively activated myeloid (M2) cells accelerate ALS progression while inhibiting experimental autoimmune encephalomyelitis. PLoS ONE. 2011;6:e26921 pubmed 出版商
Courtial N, Smink J, Kuvardina O, Leutz A, Gothert J, Lausen J. Tal1 regulates osteoclast differentiation through suppression of the master regulator of cell fusion DC-STAMP. FASEB J. 2012;26:523-32 pubmed 出版商
Youn J, Collazo M, Shalova I, Biswas S, Gabrilovich D. Characterization of the nature of granulocytic myeloid-derived suppressor cells in tumor-bearing mice. J Leukoc Biol. 2012;91:167-81 pubmed 出版商
Muto A, Mizoguchi T, Udagawa N, Ito S, Kawahara I, Abiko Y, et al. Lineage-committed osteoclast precursors circulate in blood and settle down into bone. J Bone Miner Res. 2011;26:2978-90 pubmed 出版商
Bertossi A, Aichinger M, Sansonetti P, Lech M, Neff F, Pal M, et al. Loss of Roquin induces early death and immune deregulation but not autoimmunity. J Exp Med. 2011;208:1749-56 pubmed 出版商
Cook A, Turner A, Braine E, Pobjoy J, Lenzo J, Hamilton J. Regulation of systemic and local myeloid cell subpopulations by bone marrow cell-derived granulocyte-macrophage colony-stimulating factor in experimental inflammatory arthritis. Arthritis Rheum. 2011;63:2340-51 pubmed 出版商
Lenzo J, Turner A, Cook A, Vlahos R, Anderson G, Reynolds E, et al. Control of macrophage lineage populations by CSF-1 receptor and GM-CSF in homeostasis and inflammation. Immunol Cell Biol. 2012;90:429-40 pubmed 出版商
Yan S, Wang L, Liu N, Wang Y, Chu Y. Critical role of interleukin-17/interleukin-17 receptor axis in mediating Con A-induced hepatitis. Immunol Cell Biol. 2012;90:421-8 pubmed 出版商
Qian B, Li J, Zhang H, Kitamura T, Zhang J, Campion L, et al. CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis. Nature. 2011;475:222-5 pubmed 出版商
Diao J, Zhao J, Winter E, Cattral M. Tumors suppress in situ proliferation of cytotoxic T cells by promoting differentiation of Gr-1(+) conventional dendritic cells through IL-6. J Immunol. 2011;186:5058-67 pubmed 出版商
Chitu V, Yeung Y, Yu W, Nandi S, Stanley E. Measurement of macrophage growth and differentiation. Curr Protoc Immunol. 2011;Chapter 14:Unit 14.20.1-26 pubmed 出版商
Soderquest K, Powell N, Luci C, Van Rooijen N, Hidalgo A, Geissmann F, et al. Monocytes control natural killer cell differentiation to effector phenotypes. Blood. 2011;117:4511-8 pubmed 出版商
Zhou P, Qian L, Gallo E, Deeb R, Anrather J, Gross S, et al. The scavenger receptor CD36 contributes to the neurotoxicity of bone marrow-derived monocytes through peroxynitrite production. Neurobiol Dis. 2011;42:292-9 pubmed 出版商
Christopher M, Rao M, Liu F, Woloszynek J, Link D. Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice. J Exp Med. 2011;208:251-60 pubmed 出版商
Tsuboi N, Ernandez T, Li X, Nishi H, Cullere X, Mekala D, et al. Regulation of human neutrophil Fc? receptor IIa by C5a receptor promotes inflammatory arthritis in mice. Arthritis Rheum. 2011;63:467-78 pubmed 出版商
Welch J, Klco J, Varghese N, Nagarajan R, Ley T. Rara haploinsufficiency modestly influences the phenotype of acute promyelocytic leukemia in mice. Blood. 2011;117:2460-8 pubmed 出版商
Chow Y, Zhu X, Liu L, Schwartz B, Huang X, Harlan J, et al. Role of Cdk4 in lymphocyte function and allergen response. Cell Cycle. 2010;9:4922-30 pubmed
Dolcetti L, Peranzoni E, Bronte V. Measurement of myeloid cell immune suppressive activity. Curr Protoc Immunol. 2010;Chapter 14:Unit 14.17 pubmed 出版商
Nagaoka K, Takahara K, Minamino K, Takeda T, Yoshida Y, Inaba K. Expression of C-type lectin, SIGNR3, on subsets of dendritic cells, macrophages, and monocytes. J Leukoc Biol. 2010;88:913-24 pubmed 出版商
Barber D, Mayer Barber K, Antonelli L, Wilson M, White S, Caspar P, et al. Th1-driven immune reconstitution disease in Mycobacterium avium-infected mice. Blood. 2010;116:3485-93 pubmed 出版商
de Bruin A, Buitenhuis M, Van Der Sluijs K, van Gisbergen K, Boon L, Nolte M. Eosinophil differentiation in the bone marrow is inhibited by T cell-derived IFN-gamma. Blood. 2010;116:2559-69 pubmed 出版商
Hoshino A, Iimura T, Ueha S, Hanada S, Maruoka Y, Mayahara M, et al. Deficiency of chemokine receptor CCR1 causes osteopenia due to impaired functions of osteoclasts and osteoblasts. J Biol Chem. 2010;285:28826-37 pubmed 出版商
Houthuys E, Movahedi K, De Baetselier P, Van Ginderachter J, Brouckaert P. A method for the isolation and purification of mouse peripheral blood monocytes. J Immunol Methods. 2010;359:1-10 pubmed 出版商
von Vietinghoff S, Ouyang H, Ley K. Mycophenolic acid suppresses granulopoiesis by inhibition of interleukin-17 production. Kidney Int. 2010;78:79-88 pubmed 出版商
Bankoti J, Burnett A, Navarro S, Miller A, Rase B, Shepherd D. Effects of TCDD on the fate of naive dendritic cells. Toxicol Sci. 2010;115:422-34 pubmed 出版商
Rydström A, Wick M. Salmonella inhibits monocyte differentiation into CD11c hi MHC-II hi cells in a MyD88-dependent fashion. J Leukoc Biol. 2010;87:823-32 pubmed 出版商
Martino A, Badell E, Abadie V, Balloy V, Chignard M, Mistou M, et al. Mycobacterium bovis bacillus Calmette-Guérin vaccination mobilizes innate myeloid-derived suppressor cells restraining in vivo T cell priming via IL-1R-dependent nitric oxide production. J Immunol. 2010;184:2038-47 pubmed 出版商
Kovacic J, Gupta R, Lee A, Ma M, Fang F, Tolbert C, et al. Stat3-dependent acute Rantes production in vascular smooth muscle cells modulates inflammation following arterial injury in mice. J Clin Invest. 2010;120:303-14 pubmed 出版商
Xi H, Katschke K, Helmy K, Wark P, Kljavin N, Clark H, et al. Negative regulation of autoimmune demyelination by the inhibitory receptor CLM-1. J Exp Med. 2010;207:7-16 pubmed 出版商
Chorro L, Sarde A, Li M, Woollard K, Chambon P, Malissen B, et al. Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC network. J Exp Med. 2009;206:3089-100 pubmed 出版商
Waskow C. Generation of parabiotic mice for the study of DC and DC precursor circulation. Methods Mol Biol. 2010;595:413-28 pubmed 出版商
Zanzinger K, Schellack C, Nausch N, Cerwenka A. Regulation of triggering receptor expressed on myeloid cells 1 expression on mouse inflammatory monocytes. Immunology. 2009;128:185-95 pubmed 出版商
Sottnik J, U Ren L, Thamm D, Withrow S, Dow S. Chronic bacterial osteomyelitis suppression of tumor growth requires innate immune responses. Cancer Immunol Immunother. 2010;59:367-78 pubmed 出版商
Green C, Liu T, Montel V, Hsiao G, Lester R, Subramaniam S, et al. Chemoattractant signaling between tumor cells and macrophages regulates cancer cell migration, metastasis and neovascularization. PLoS ONE. 2009;4:e6713 pubmed 出版商
Holub M, Cheng C, Mott S, Wintermeyer P, Van Rooijen N, Gregory S. Neutrophils sequestered in the liver suppress the proinflammatory response of Kupffer cells to systemic bacterial infection. J Immunol. 2009;183:3309-16 pubmed 出版商
Serbina N, Hohl T, Cherny M, Pamer E. Selective expansion of the monocytic lineage directed by bacterial infection. J Immunol. 2009;183:1900-10 pubmed 出版商
Kuligowski M, Kwan R, Lo C, Wong C, James W, Bourges D, et al. Antimyeloperoxidase antibodies rapidly induce alpha-4-integrin-dependent glomerular neutrophil adhesion. Blood. 2009;113:6485-94 pubmed 出版商
Varol C, Landsman L, Jung S. Probing in vivo origins of mononuclear phagocytes by conditional ablation and reconstitution. Methods Mol Biol. 2009;531:71-87 pubmed 出版商
Auffray C, Fogg D, Narni Mancinelli E, Senechal B, Trouillet C, Saederup N, et al. CX3CR1+ CD115+ CD135+ common macrophage/DC precursors and the role of CX3CR1 in their response to inflammation. J Exp Med. 2009;206:595-606 pubmed 出版商
King I, Dickendesher T, Segal B. Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease. Blood. 2009;113:3190-7 pubmed 出版商
Grabner R, Lotzer K, Döpping S, Hildner M, Radke D, Beer M, et al. Lymphotoxin beta receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE-/- mice. J Exp Med. 2009;206:233-48 pubmed 出版商
Sköld M, Behar S. Tuberculosis triggers a tissue-dependent program of differentiation and acquisition of effector functions by circulating monocytes. J Immunol. 2008;181:6349-60 pubmed
Tada T, Shin M, Fukushima H, Okabe K, Ozeki S, Okamoto M, et al. Oral squamous cell carcinoma cells modulate osteoclast function by RANKL-dependent and -independent mechanisms. Cancer Lett. 2009;274:126-31 pubmed 出版商
Engel D, Maurer J, Tittel A, Weisheit C, Cavlar T, Schumak B, et al. CCR2 mediates homeostatic and inflammatory release of Gr1(high) monocytes from the bone marrow, but is dispensable for bladder infiltration in bacterial urinary tract infection. J Immunol. 2008;181:5579-86 pubmed
Chen Y, Wang X, Di L, Fu G, Chen Y, Bai L, et al. Phospholipase Cgamma2 mediates RANKL-stimulated lymph node organogenesis and osteoclastogenesis. J Biol Chem. 2008;283:29593-601 pubmed 出版商
Jin W, Chang M, Paul E, Babu G, Lee A, Reiley W, et al. Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice. J Clin Invest. 2008;118:1858-66 pubmed 出版商
Sawanobori Y, Ueha S, Kurachi M, Shimaoka T, Talmadge J, Abe J, et al. Chemokine-mediated rapid turnover of myeloid-derived suppressor cells in tumor-bearing mice. Blood. 2008;111:5457-66 pubmed 出版商
Carlson T, Kroenke M, Rao P, Lane T, Segal B. The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease. J Exp Med. 2008;205:811-23 pubmed 出版商
Treese C, Mittag A, Lange F, Tarnok A, Loesche A, Emmrich F, et al. Characterization of fibroblasts responsible for cartilage destruction in arthritis. Cytometry A. 2008;73:351-60 pubmed 出版商
Cullere X, Lauterbach M, Tsuboi N, Mayadas T. Neutrophil-selective CD18 silencing using RNA interference in vivo. Blood. 2008;111:3591-8 pubmed 出版商
Poulin L, Henri S, de Bovis B, Devilard E, Kissenpfennig A, Malissen B. The dermis contains langerin+ dendritic cells that develop and function independently of epidermal Langerhans cells. J Exp Med. 2007;204:3119-31 pubmed
Shaftel S, Carlson T, Olschowka J, Kyrkanides S, Matousek S, O Banion M. Chronic interleukin-1beta expression in mouse brain leads to leukocyte infiltration and neutrophil-independent blood brain barrier permeability without overt neurodegeneration. J Neurosci. 2007;27:9301-9 pubmed
Niki Y, Takaishi H, Takito J, Miyamoto T, Kosaki N, Matsumoto H, et al. Administration of cyclooxygenase-2 inhibitor reduces joint inflammation but exacerbates osteopenia in IL-1 alpha transgenic mice due to GM-CSF overproduction. J Immunol. 2007;179:639-46 pubmed
Meuter S, Schaerli P, Roos R, Brandau O, Bösl M, von Andrian U, et al. Murine CXCL14 is dispensable for dendritic cell function and localization within peripheral tissues. Mol Cell Biol. 2007;27:983-92 pubmed
Krysinska H, Hoogenkamp M, Ingram R, Wilson N, Tagoh H, Laslo P, et al. A two-step, PU.1-dependent mechanism for developmentally regulated chromatin remodeling and transcription of the c-fms gene. Mol Cell Biol. 2007;27:878-87 pubmed
Schlueter A, Glasgow J. Phenotypic comparison of multiple monocyte-related populations in murine peripheral blood and bone marrow. Cytometry A. 2006;69:281-90 pubmed
Yao Z, Li P, Zhang Q, Schwarz E, Keng P, Arbini A, et al. Tumor necrosis factor-alpha increases circulating osteoclast precursor numbers by promoting their proliferation and differentiation in the bone marrow through up-regulation of c-Fms expression. J Biol Chem. 2006;281:11846-55 pubmed
Sköld M, Xiong X, Illarionov P, Besra G, Behar S. Interplay of cytokines and microbial signals in regulation of CD1d expression and NKT cell activation. J Immunol. 2005;175:3584-93 pubmed
Fukushima H, Jimi E, Kajiya H, Motokawa W, Okabe K. Parathyroid-hormone-related protein induces expression of receptor activator of NF-{kappa}B ligand in human periodontal ligament cells via a cAMP/protein kinase A-independent pathway. J Dent Res. 2005;84:329-34 pubmed
Wu X, Pan G, McKenna M, Zayzafoon M, Xiong W, McDonald J. RANKL regulates Fas expression and Fas-mediated apoptosis in osteoclasts. J Bone Miner Res. 2005;20:107-16 pubmed
产品信息
产品类型 :
抗体
产品名称 :
CD115 (c-fms) Monoclonal Antibody (AFS98), Biotin, eBioscience™
目录# :
13-1152-85
规格 :
500微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.25 µg/test
物种 :
小鼠
克隆 :
AFS98
抗体亚型 :
IgG2a, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
CSF1R (colony stimulating factor 1 receptor) is a cytokine that controls the production, differentiation, and function of macrophages. CSF1R mediates most if not all of the biological effects of CSF1. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. CSF1R is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in the gene encoding CSF1R have been associated with a predisposition to myeloid malignancy.Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and plays an important role in innate immunity and in inflammatory processes. The first intron of the CSF1R gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Mutations in the CSF1R gene have been associated with a predisposition to myeloid malignancy.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.25 µg/test
别名 :
AI323359; CD115; CD115 antigen; C-FMS; colony stimulating factor 1 receptor; colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog; CSF-1 receptor; CSF1R; CSF-1R; CSF-1-R; Csfmr; CSFR; EC 2.7.10.1; FIM2; Fim-2; FMS; fms proto-oncogene; HDLS; kinase CSFR; macrophage colony stimulating factor I receptor; macrophage colony-stimulating factor 1 receptor; McDonough feline sarcoma viral (v-fms) oncogene homolog; M-CSFR; M-CSF-R; mrfms; OTTHUMP00000224093; protein-tyrosine kinase; proto-oncogene c-Fms; proto-oncogene fms
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国