产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
E钙粘蛋白单克隆抗体(ECCD-1)
目录 :
13-1800
规格 :
100微克
价格 :
449美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
ECCD-1
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 抑制或激活实验
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 12
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 1e
Kress T, Pellanda P, Pellegrinet L, Bianchi V, Nicoli P, Doni M, et al. Identification of MYC-Dependent Transcriptional Programs in Oncogene-Addicted Liver Tumors. Cancer Res. 2016;76:3463-72 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 7
Boddupally K, Wang G, Chen Y, Kobielak A. Lgr5 Marks Neural Crest Derived Multipotent Oral Stromal Stem Cells. Stem Cells. 2016;34:720-31 pubmed 出版商
  • 抑制或激活实验; 人类; 200 ug/ml; 图 1
  • 免疫细胞化学; 人类; 10 ug/ml; 图 1
Moore R, Cherry J, Mathur V, Cohen R, Grumet M, Moghe P. E-cadherin-expressing feeder cells promote neural lineage restriction of human embryonic stem cells. Stem Cells Dev. 2012;21:30-41 pubmed 出版商
  • 抑制或激活实验; 小鼠; 1.0 ug/ml; 图 5a
Karpowicz P, Willaime Morawek S, Balenci L, DeVeale B, Inoue T, van der Kooy D. E-Cadherin regulates neural stem cell self-renewal. J Neurosci. 2009;29:3885-96 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 4
Wei C, Larsen M, Hoffman M, Yamada K. Self-organization and branching morphogenesis of primary salivary epithelial cells. Tissue Eng. 2007;13:721-35 pubmed
  • 抑制或激活实验; 小鼠
  • 流式细胞仪; 小鼠
Duguay D, Foty R, Steinberg M. Cadherin-mediated cell adhesion and tissue segregation: qualitative and quantitative determinants. Dev Biol. 2003;253:309-23 pubmed
  • 免疫印迹; 人类
Schmeiser K, Grand R. The fate of E- and P-cadherin during the early stages of apoptosis. Cell Death Differ. 1999;6:377-86 pubmed
Gao X, Acharya B, Engl W, de Mets R, Thiery J, Yap A, et al. Probing compression versus stretch activated recruitment of cortical actin and apical junction proteins using mechanical stimulations of suspended doublets. APL Bioeng. 2018;2:026111 pubmed 出版商
Wang H, Tong D, El Gehani F, Tekpetey F, Kidder G. Connexin expression and gap junctional coupling in human cumulus cells: contribution to embryo quality. J Cell Mol Med. 2009;13:972-84 pubmed 出版商
Sevilla L, Nachat R, Groot K, Klement J, Uitto J, Djian P, et al. Mice deficient in involucrin, envoplakin, and periplakin have a defective epidermal barrier. J Cell Biol. 2007;179:1599-612 pubmed 出版商
Tinkle C, Lechler T, Pasolli H, Fuchs E. Conditional targeting of E-cadherin in skin: insights into hyperproliferative and degenerative responses. Proc Natl Acad Sci U S A. 2004;101:552-7 pubmed
Takeichi M. The cadherins: cell-cell adhesion molecules controlling animal morphogenesis. Development. 1988;102:639-55 pubmed
产品信息
产品类型 :
抗体
产品名称 :
E钙粘蛋白单克隆抗体(ECCD-1)
目录# :
13-1800
规格 :
100微克
价格 :
449美元
克隆性 :
单克隆
纯度 :
纯化
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Inhibition Assays: 200 µg/mL
物种 :
小鼠
克隆 :
ECCD-1
抗体亚型 :
IgG2b
储存 :
4° C
描述 :
E-Cadherin (epithelial cadherin) is a classical cadherin from the cadherin (alcium dependent adhesion protein) superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. E-cadherin plays a central role in the growth and development of cells by controlling tissue architecture, and maintenance of tissue integrity. In humans, E-cadherin is encoded by the CDH1 gene present on chromosome 16. Studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.
免疫原 :
小鼠畸胎瘤细胞株F9
格式 :
冻干
应用w/稀释 :
Inhibition Assays: 200 µg/mL
别名 :
AA960649; Arc-1; cadherin 1; cadherin 1, E-cadherin (epithelial); cadherin 1, epithelial; cadherin 1, type 1; cadherin 1, type 1, E-cadherin (epithelial); cadherin e; Cadherin-1; cadherin-E; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324; CDH1; CDHE; cell adhesion molecule; cell-CAM 120/80; ECAD; E-cad; E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3; Ecadherin; E-cadherin; E-cadherin 1; E-Cadherin phospho; Epithelial cadherin; hab; half baked; LCAM; L-CAM; phospho cadherin 1; phospho E-Cadherin; phospho LCAM; phospho S838; phospho UVO; S840; S840 E-Cadherin; Ser840; Ser840 E-Cadherin; Um; UVO; Uvomorulin
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国