产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
E钙粘蛋白单克隆抗体(ECCD-2)
目录 :
13-1900
规格 :
100微克
价格 :
美国455.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
ECCD-2
反应物种 :
仓鼠, 人类, 小鼠,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫印迹基因敲除验证, 免疫组化基因敲除验证
更多信息或购买 :
文章摘录数: 254
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 图 s2b
Osborne J, Kinney M, Han A, Akinnola K, Yermalovich A, Vo L, et al. Lin28 paralogs regulate lung branching morphogenesis. Cell Rep. 2021;36:109408 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500; 图 3k
Carter P, Schnell U, Chaney C, TONG B, Pan X, ye J, et al. Deletion of Lats1/2 in adult kidney epithelia leads to renal cell carcinoma. J Clin Invest. 2021;131: pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 1s3a
Zhang K, Yao E, Lin C, Chou Y, Wong J, Li J, et al. A mammalian Wnt5a-Ror2-Vangl2 axis controls the cytoskeleton and confers cellular properties required for alveologenesis. elife. 2020;9: pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 3d
Calandrini C, Schutgens F, Oka R, Margaritis T, Candelli T, Mathijsen L, et al. An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity. Nat Commun. 2020;11:1310 pubmed 出版商
  • 免疫组化; 小鼠; 图 1j
Sozen B, Cox A, De Jonghe J, Bao M, Hollfelder F, Glover D, et al. Self-Organization of Mouse Stem Cells into an Extended Potential Blastoid. Dev Cell. 2019;51:698-712.e8 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 s4p
Ouadah Y, Rojas E, Riordan D, Capostagno S, Kuo C, Krasnow M. Rare Pulmonary Neuroendocrine Cells Are Stem Cells Regulated by Rb, p53, and Notch. Cell. 2019;179:403-416.e23 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1b
Padmanaban V, Krol I, Suhail Y, Szczerba B, Aceto N, Bader J, et al. E-cadherin is required for metastasis in multiple models of breast cancer. Nature. 2019;573:439-444 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 4s3b
Saatcioglu H, Kano M, Horn H, Zhang L, Samore W, Nagykery N, et al. Single-cell sequencing of neonatal uterus reveals an Misr2+ endometrial progenitor indispensable for fertility. elife. 2019;8: pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 6c
Li L, Kang H, Zhang Q, D Agati V, Al Awqati Q, Lin F. FoxO3 activation in hypoxic tubules prevents chronic kidney disease. J Clin Invest. 2019;129:2374-2389 pubmed 出版商
  • 免疫细胞化学; 犬; 1:500; 图 s1a
Ibar C, Kirichenko E, Keepers B, Enners E, Fleisch K, Irvine K. Tension-dependent regulation of mammalian Hippo signaling through LIMD1. J Cell Sci. 2018;131: pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 2n
Lin C, Yao E, Zhang K, Jiang X, Croll S, Thompson Peer K, et al. YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis. elife. 2017;6: pubmed 出版商
  • 流式细胞仪; 人类; 图 1b
Jiang F, Li K, Archer M, Mehta M, Jamieson E, Charles A, et al. Differentiation of Islet Progenitors Regulated by Nicotinamide into Transcriptome-Verified β Cells That Ameliorate Diabetes. Stem Cells. 2017;35:1341-1354 pubmed 出版商
  • 免疫组化; 小鼠; 1:250; 图 5c
Maatouk D, Natarajan A, Shibata Y, Song L, Crawford G, Ohler U, et al. Genome-wide identification of regulatory elements in Sertoli cells. Development. 2017;144:720-730 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 s2a
  • 免疫印迹; 人类; 1:500; 图 s2e
Priya R, Liang X, Teo J, Duszyc K, Yap A, Gomez G. ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens. Mol Biol Cell. 2017;28:12-20 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 e1d
Nonomura K, Woo S, Chang R, Gillich A, Qiu Z, Francisco A, et al. Piezo2 senses airway stretch and mediates lung inflation-induced apnoea. Nature. 2017;541:176-181 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 5g
Lin J, Khan M, Zapiec B, Mombaerts P. Efficient derivation of extraembryonic endoderm stem cell lines from mouse postimplantation embryos. Sci Rep. 2016;6:39457 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 4d
Platet N, Hinkel I, Richert L, Murdamoothoo D, Moufok Sadoun A, Vanier M, et al. The tumor suppressor CDX2 opposes pro-metastatic biomechanical modifications of colon cancer cells through organization of the actin cytoskeleton. Cancer Lett. 2017;386:57-64 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 5d
Yousefi M, Li N, Nakauka Ddamba A, Wang S, Davidow K, Schoenberger J, et al. Msi RNA-binding proteins control reserve intestinal stem cell quiescence. J Cell Biol. 2016;215:401-413 pubmed
  • 免疫细胞化学; 犬; 图 4d
Cheng H, Burroughs Garcia J, Birkness J, Trinidad J, Deans M. Disparate Regulatory Mechanisms Control Fat3 and P75NTR Protein Transport through a Conserved Kif5-Interaction Domain. PLoS ONE. 2016;11:e0165519 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1d
Rouzaire M, Comptour A, Belville C, Bouvier D, Clairefond G, Ponelle F, et al. All-trans retinoic acid promotes wound healing of primary amniocytes through the induction of LOXL4, a member of the lysyl oxidase family. Int J Biochem Cell Biol. 2016;81:10-19 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 3
Ren S, Luo Y, Chen H, Warburton D, Lam H, Wang L, et al. Inactivation of Tsc2 in Mesoderm-Derived Cells Causes Polycystic Kidney Lesions and Impairs Lung Alveolarization. Am J Pathol. 2016;186:3261-3272 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 1a
Priya R, Wee K, Budnar S, Gomez G, Yap A, Michael M. Coronin 1B supports RhoA signaling at cell-cell junctions through Myosin II. Cell Cycle. 2016;15:3033-3041 pubmed
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 4a
Bain V, Gordon J, O Neil J, Ramos I, Richie E, Manley N. Tissue-specific roles for sonic hedgehog signaling in establishing thymus and parathyroid organ fate. Development. 2016;143:4027-4037 pubmed
  • 免疫组化-石蜡切片; 人类; 图 4g
Coburn L, Lopez H, Caldwell B, Moussa E, Yap C, Priya R, et al. Contact inhibition of locomotion and mechanical cross-talk between cell-cell and cell-substrate adhesion determine the pattern of junctional tension in epithelial cell aggregates. Mol Biol Cell. 2016;27:3436-3448 pubmed
  • 免疫组化; 小鼠; 1:1000; 图 1
Laresgoiti U, Nikolić M, Rao C, Brady J, Richardson R, Batchen E, et al. Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate. Development. 2016;143:3686-3699 pubmed
  • 免疫组化-冰冻切片; 小鼠; 图 4a
Belinson H, Savage A, Fadrosh D, Kuo Y, Lin D, Valladares R, et al. Dual epithelial and immune cell function of Dvl1 regulates gut microbiota composition and intestinal homeostasis. JCI Insight. 2016;1: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:1000
Freddo A, Shoffner S, Shao Y, Taniguchi K, Grosse A, Guysinger M, et al. Coordination of signaling and tissue mechanics during morphogenesis of murine intestinal villi: a role for mitotic cell rounding. Integr Biol (Camb). 2016;8:918-28 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:2000; 图 s5
Perdigoto C, Dauber K, Bar C, Tsai P, Valdes V, Cohen I, et al. Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development. PLoS Genet. 2016;12:e1006151 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 7
Cox A, Barrandon O, Cai E, Rios J, Chavez J, Bonnyman C, et al. Resolving Discrepant Findings on ANGPTL8 in ?-Cell Proliferation: A Collaborative Approach to Resolving the Betatrophin Controversy. PLoS ONE. 2016;11:e0159276 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200
  • 免疫细胞化学; 小鼠; 1:200; 图 5c
Cantú A, Altshuler Keylin S, Laird D. Discrete somatic niches coordinate proliferation and migration of primordial germ cells via Wnt signaling. J Cell Biol. 2016;214:215-29 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 2
  • 流式细胞仪; 小鼠; 图 2
Li N, Yousefi M, Nakauka Ddamba A, Tobias J, Jensen S, Morrisey E, et al. Heterogeneity in readouts of canonical wnt pathway activity within intestinal crypts. Dev Dyn. 2016;245:822-33 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100; 图 2
Bai H, Zhu Q, Surcel A, Luo T, Ren Y, Guan B, et al. Yes-associated protein impacts adherens junction assembly through regulating actin cytoskeleton organization. Am J Physiol Gastrointest Liver Physiol. 2016;311:G396-411 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 s3
  • 免疫细胞化学; 仓鼠; 1:200; 图 4d
  • 免疫细胞化学; 犬; 1:200; 图 1a
Chen C, Wang S, Chan P, Shen M, Chen H. Phosphorylation of E-cadherin at threonine 790 by protein kinase C? reduces ?-catenin binding and suppresses the function of E-cadherin. Oncotarget. 2016;7:37260-37276 pubmed 出版商
  • 免疫组化; 小鼠; 图 5
Benjamin J, Van Der Meer R, Im A, Plosa E, Zaynagetdinov R, Burman A, et al. Epithelial-Derived Inflammation Disrupts Elastin Assembly and Alters Saccular Stage Lung Development. Am J Pathol. 2016;186:1786-1800 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 1
Rios A, Fu N, Jamieson P, Pal B, Whitehead L, Nicholas K, et al. Essential role for a novel population of binucleated mammary epithelial cells in lactation. Nat Commun. 2016;7:11400 pubmed 出版商
  • 免疫印迹; 人类; 1:100; 图 2
Choi V, Herrou J, Hecht A, Teoh W, Turner J, Crosson S, et al. Activation of Bacteroides fragilis toxin by a novel bacterial protease contributes to anaerobic sepsis in mice. Nat Med. 2016;22:563-7 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:3000; 图 4
Balasooriya G, Johnson J, Basson M, Rawlins E. An FGFR1-SPRY2 Signaling Axis Limits Basal Cell Proliferation in the Steady-State Airway Epithelium. Dev Cell. 2016;37:85-97 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 1
Tan S, Krasnow M. Developmental origin of lung macrophage diversity. Development. 2016;143:1318-27 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:400; 图 2
  • 免疫印迹; 小鼠; 1:800; 图 2
Thakur A, Nigri J, Lac S, Leca J, Bressy C, Berthezene P, et al. TAp73 loss favors Smad-independent TGF-β signaling that drives EMT in pancreatic ductal adenocarcinoma. Cell Death Differ. 2016;23:1358-70 pubmed 出版商
  • 免疫组化; 小鼠; 3:1000; 图 1
Loebel D, Plageman T, Tang T, Jones V, Muccioli M, Tam P. Thyroid bud morphogenesis requires CDC42- and SHROOM3-dependent apical constriction. Biol Open. 2016;5:130-9 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 6
Gao X, Bali A, Randell S, Hogan B. GRHL2 coordinates regeneration of a polarized mucociliary epithelium from basal stem cells. J Cell Biol. 2015;211:669-82 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 6
Eisses J, Criscimanna A, Dionise Z, Orabi A, Javed T, Sarwar S, et al. Valproic Acid Limits Pancreatic Recovery after Pancreatitis by Inhibiting Histone Deacetylases and Preventing Acinar Redifferentiation Programs. Am J Pathol. 2015;185:3304-15 pubmed 出版商
  • 免疫细胞化学; 小鼠
Gamat M, Malinowski R, Parkhurst L, Steinke L, Marker P. Ornithine Decarboxylase Activity Is Required for Prostatic Budding in the Developing Mouse Prostate. PLoS ONE. 2015;10:e0139522 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 2
Buchert M, Rohde F, Eissmann M, Tebbutt N, Williams B, Tan C, et al. A hypermorphic epithelial β-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations. Dis Model Mech. 2015;8:1361-73 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 s3
  • 免疫印迹; 人类; 1:500; 图 s1h
Priya R, Gomez G, Budnar S, Verma S, Cox H, Hamilton N, et al. Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions. Nat Cell Biol. 2015;17:1282-93 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 2h
Tan C, Hirokawa Y, Burgess A. Analysis of Wnt signalling dynamics during colon crypt development in 3D culture. Sci Rep. 2015;5:11036 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 3
Causton B, Ramadas R, CHO J, Jones K, Pardo Saganta A, Rajagopal J, et al. CARMA3 Is Critical for the Initiation of Allergic Airway Inflammation. J Immunol. 2015;195:683-94 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 3
Liu C, Dubé P, Girish N, Reddy A, Polk D. Optical reconstruction of murine colorectal mucosa at cellular resolution. Am J Physiol Gastrointest Liver Physiol. 2015;308:G721-35 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 3
Guillaumond F, Bidaut G, Ouaissi M, Servais S, Gouirand V, Olivares O, et al. Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma. Proc Natl Acad Sci U S A. 2015;112:2473-8 pubmed 出版商
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WANG Y, McAllister F, Bailey J, Scott S, Hendley A, Leach S, et al. Dicer is required for maintenance of adult pancreatic acinar cell identity and plays a role in Kras-driven pancreatic neoplasia. PLoS ONE. 2014;9:e113127 pubmed 出版商
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Plosa E, Young L, Gulleman P, Polosukhin V, Zaynagetdinov R, Benjamin J, et al. Epithelial β1 integrin is required for lung branching morphogenesis and alveolarization. Development. 2014;141:4751-62 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠
  • 免疫印迹; 小鼠
DiTommaso T, Cottle D, Pearson H, Schlüter H, Kaur P, Humbert P, et al. Keratin 76 is required for tight junction function and maintenance of the skin barrier. PLoS Genet. 2014;10:e1004706 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 4
Yoshida T, Iwata T, Takai Y, Birchmeier W, Yamato M, Okano T. Afadin requirement for cytokine expressions in keratinocytes during chemically induced inflammation in mice. Genes Cells. 2014;19:842-52 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 7b
Alanis D, Chang D, Akiyama H, Krasnow M, Chen J. Two nested developmental waves demarcate a compartment boundary in the mouse lung. Nat Commun. 2014;5:3923 pubmed 出版商
  • 免疫组化; 小鼠
Baluk P, Phillips K, Yao L, Adams A, Nitschké M, McDonald D. Neutrophil dependence of vascular remodeling after Mycoplasma infection of mouse airways. Am J Pathol. 2014;184:1877-89 pubmed 出版商
  • 免疫细胞化学; 小鼠
Huang T, Rivera Perez J. Senescence-associated ?-galactosidase activity marks the visceral endoderm of mouse embryos but is not indicative of senescence. Genesis. 2014;52:300-8 pubmed 出版商
  • 免疫组化基因敲除验证; 小鼠; 1:250; 图 s1a
  • 免疫印迹基因敲除验证; 小鼠; 1:1000; 图 s1a
  • 免疫组化-冰冻切片; 小鼠; 图 s1f
Shamir E, Pappalardo E, Jorgens D, Coutinho K, Tsai W, Aziz K, et al. Twist1-induced dissemination preserves epithelial identity and requires E-cadherin. J Cell Biol. 2014;204:839-56 pubmed 出版商
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Hirokawa Y, Yip K, Tan C, Burgess A. Colonic myofibroblast cell line stimulates colonoid formation. Am J Physiol Gastrointest Liver Physiol. 2014;306:G547-56 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Fantozzi A, Gruber D, Pisarsky L, Heck C, Kunita A, Yilmaz M, et al. VEGF-mediated angiogenesis links EMT-induced cancer stemness to tumor initiation. Cancer Res. 2014;74:1566-75 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 4
  • 免疫印迹; 小鼠; 图 4
Shahbazi M, Megias D, Epifano C, Akhmanova A, Gundersen G, Fuchs E, et al. CLASP2 interacts with p120-catenin and governs microtubule dynamics at adherens junctions. J Cell Biol. 2013;203:1043-61 pubmed 出版商
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Tan C, Hirokawa Y, Gardiner B, Smith D, Burgess A. Colon cryptogenesis: asymmetric budding. PLoS ONE. 2013;8:e78519 pubmed 出版商
  • 免疫组化; 小鼠; 图 6
Castelli M, Boca M, Chiaravalli M, Ramalingam H, Rowe I, Distefano G, et al. Polycystin-1 binds Par3/aPKC and controls convergent extension during renal tubular morphogenesis. Nat Commun. 2013;4:2658 pubmed 出版商
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Tan F, Vladar E, Ma L, Fuentealba L, Hoh R, Espinoza F, et al. Myb promotes centriole amplification and later steps of the multiciliogenesis program. Development. 2013;140:4277-86 pubmed 出版商
  • 免疫细胞化学; 人类
Judson R, Greve T, Parchem R, Blelloch R. MicroRNA-based discovery of barriers to dedifferentiation of fibroblasts to pluripotent stem cells. Nat Struct Mol Biol. 2013;20:1227-35 pubmed 出版商
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Mann E, Harmel Laws E, Cohen M, Steinbrecher K. Guanylate cyclase C limits systemic dissemination of a murine enteric pathogen. BMC Gastroenterol. 2013;13:135 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500; 图 6
Das A, Tanigawa S, Karner C, Xin M, Lum L, Chen C, et al. Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation. Nat Cell Biol. 2013;15:1035-44 pubmed 出版商
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Cedervall J, Zhang Y, Ringvall M, Thulin A, Moustakas A, Jahnen Dechent W, et al. HRG regulates tumor progression, epithelial to mesenchymal transition and metastasis via platelet-induced signaling in the pre-tumorigenic microenvironment. Angiogenesis. 2013;16:889-902 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Tsai Y, Disson O, Bierne H, Lecuit M. Murinization of internalin extends its receptor repertoire, altering Listeria monocytogenes cell tropism and host responses. PLoS Pathog. 2013;9:e1003381 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:1000; 图 2
Biehs B, Hu J, Strauli N, Sangiorgi E, Jung H, Heber R, et al. BMI1 represses Ink4a/Arf and Hox genes to regulate stem cells in the rodent incisor. Nat Cell Biol. 2013;15:846-52 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1
Xu X, Jin D, Durgan J, Hall A. LKB1 controls human bronchial epithelial morphogenesis through p114RhoGEF-dependent RhoA activation. Mol Cell Biol. 2013;33:2671-82 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1
Priya R, Yap A, Gomez G. E-cadherin supports steady-state Rho signaling at the epithelial zonula adherens. Differentiation. 2013;86:133-40 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 1
  • 免疫印迹; 小鼠; 1:1000
Correia A, Mori H, Chen E, Schmitt F, Bissell M. The hemopexin domain of MMP3 is responsible for mammary epithelial invasion and morphogenesis through extracellular interaction with HSP90?. Genes Dev. 2013;27:805-17 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Tiwari N, Meyer Schaller N, Arnold P, Antoniadis H, Pachkov M, van Nimwegen E, et al. Klf4 is a transcriptional regulator of genes critical for EMT, including Jnk1 (Mapk8). PLoS ONE. 2013;8:e57329 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500; 图 S8
Chou J, Lin J, Brenot A, Kim J, Provot S, Werb Z. GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression. Nat Cell Biol. 2013;15:201-13 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 S1
Chen J, Krasnow M. Integrin Beta 1 suppresses multilayering of a simple epithelium. PLoS ONE. 2012;7:e52886 pubmed 出版商
  • 免疫组化; 小鼠; 图 4
Waldmeier L, Meyer Schaller N, Diepenbruck M, Christofori G. Py2T murine breast cancer cells, a versatile model of TGF?-induced EMT in vitro and in vivo. PLoS ONE. 2012;7:e48651 pubmed 出版商
  • 免疫组化; 人类; 1:500; 图 5
Magudia K, Lahoz A, Hall A. K-Ras and B-Raf oncogenes inhibit colon epithelial polarity establishment through up-regulation of c-myc. J Cell Biol. 2012;198:185-94 pubmed 出版商
  • 免疫细胞化学; 犬; 图 3
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Collado M, Thiede B, Baker W, Askew C, Igbani L, Corwin J. The postnatal accumulation of junctional E-cadherin is inversely correlated with the capacity for supporting cells to convert directly into sensory hair cells in mammalian balance organs. J Neurosci. 2011;31:11855-66 pubmed 出版商
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Durgan J, Kaji N, Jin D, Hall A. Par6B and atypical PKC regulate mitotic spindle orientation during epithelial morphogenesis. J Biol Chem. 2011;286:12461-74 pubmed 出版商
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Yoshida T, Miyoshi J, Takai Y, Thesleff I. Cooperation of nectin-1 and nectin-3 is required for normal ameloblast function and crown shape development in mouse teeth. Dev Dyn. 2010;239:2558-69 pubmed 出版商
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Wallace S, Magalhaes A, Hall A. The Rho target PRK2 regulates apical junction formation in human bronchial epithelial cells. Mol Cell Biol. 2011;31:81-91 pubmed 出版商
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Lim M, Adsay N, Grignon D, Osunkoya A. E-cadherin expression in plasmacytoid, signet ring cell and micropapillary variants of urothelial carcinoma: comparison with usual-type high-grade urothelial carcinoma. Mod Pathol. 2011;24:241-7 pubmed 出版商
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Wallace S, Durgan J, Jin D, Hall A. Cdc42 regulates apical junction formation in human bronchial epithelial cells through PAK4 and Par6B. Mol Biol Cell. 2010;21:2996-3006 pubmed 出版商
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Kopinke D, Murtaugh L. Exocrine-to-endocrine differentiation is detectable only prior to birth in the uninjured mouse pancreas. BMC Dev Biol. 2010;10:38 pubmed 出版商
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Wiley L, Dattilo L, Kang K, Giovannini M, Beebe D. The tumor suppressor merlin is required for cell cycle exit, terminal differentiation, and cell polarity in the developing murine lens. Invest Ophthalmol Vis Sci. 2010;51:3611-8 pubmed 出版商
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MANICONE A, Huizar I, McGuire J. Matrilysin (Matrix Metalloproteinase-7) regulates anti-inflammatory and antifibrotic pulmonary dendritic cells that express CD103 (alpha(E)beta(7)-integrin). Am J Pathol. 2009;175:2319-31 pubmed 出版商
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Banh C, Fugere C, Brossay L. Immunoregulatory functions of KLRG1 cadherin interactions are dependent on forward and reverse signaling. Blood. 2009;114:5299-306 pubmed 出版商
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Cattin A, Le Beyec J, Barreau F, Saint Just S, Houllier A, Gonzalez F, et al. Hepatocyte nuclear factor 4alpha, a key factor for homeostasis, cell architecture, and barrier function of the adult intestinal epithelium. Mol Cell Biol. 2009;29:6294-308 pubmed 出版商
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Wenderfer S, Dubinsky W, Hernandez Sanabria M, Braun M. Urine proteome analysis in murine nephrotoxic serum nephritis. Am J Nephrol. 2009;30:450-8 pubmed 出版商
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den Elzen N, Buttery C, Maddugoda M, Ren G, Yap A. Cadherin adhesion receptors orient the mitotic spindle during symmetric cell division in mammalian epithelia. Mol Biol Cell. 2009;20:3740-50 pubmed 出版商
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Le T, Conley K, Brown N. Jagged 1 is necessary for normal mouse lens formation. Dev Biol. 2009;328:118-26 pubmed 出版商
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Cook M, Coveney D, Batchvarov I, Nadeau J, Capel B. BAX-mediated cell death affects early germ cell loss and incidence of testicular teratomas in Dnd1(Ter/Ter) mice. Dev Biol. 2009;328:377-83 pubmed 出版商
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Karpowicz P, Willaime Morawek S, Balenci L, DeVeale B, Inoue T, van der Kooy D. E-Cadherin regulates neural stem cell self-renewal. J Neurosci. 2009;29:3885-96 pubmed 出版商
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Rhee K, Wu S, Wu X, Huso D, Karim B, Franco A, et al. Induction of persistent colitis by a human commensal, enterotoxigenic Bacteroides fragilis, in wild-type C57BL/6 mice. Infect Immun. 2009;77:1708-18 pubmed 出版商
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Jaffe A, Kaji N, Durgan J, Hall A. Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis. J Cell Biol. 2008;183:625-33 pubmed 出版商
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Morel E, Fouquet S, Strup Perrot C, Pichol Thievend C, Thievend C, Petit C, et al. The cellular prion protein PrP(c) is involved in the proliferation of epithelial cells and in the distribution of junction-associated proteins. PLoS ONE. 2008;3:e3000 pubmed 出版商
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Singh P, Chen C, Pal Ghosh S, Stepp M, Sheppard D, Van De Water L. Loss of integrin alpha9beta1 results in defects in proliferation, causing poor re-epithelialization during cutaneous wound healing. J Invest Dermatol. 2009;129:217-28 pubmed 出版商
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Agarwal S, Lee D, Kiener H, Brenner M. Coexpression of two mesenchymal cadherins, cadherin 11 and N-cadherin, on murine fibroblast-like synoviocytes. Arthritis Rheum. 2008;58:1044-54 pubmed 出版商
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Hebbard L, Garlatti M, Young L, Cardiff R, Oshima R, Ranscht B. T-cadherin supports angiogenesis and adiponectin association with the vasculature in a mouse mammary tumor model. Cancer Res. 2008;68:1407-16 pubmed 出版商
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Marose T, Merkel C, McMahon A, Carroll T. Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state. Dev Biol. 2008;314:112-26 pubmed 出版商
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Kaimori A, Potter J, Kaimori J, Wang C, Mezey E, Koteish A. Transforming growth factor-beta1 induces an epithelial-to-mesenchymal transition state in mouse hepatocytes in vitro. J Biol Chem. 2007;282:22089-101 pubmed
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Perrin Tricaud C, Rutishauser U, Tricaud N. P120 catenin is required for thickening of Schwann cell myelin. Mol Cell Neurosci. 2007;35:120-9 pubmed
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Kashiwagi M, Morgan B, Georgopoulos K. The chromatin remodeler Mi-2beta is required for establishment of the basal epidermis and normal differentiation of its progeny. Development. 2007;134:1571-82 pubmed
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Wei C, Larsen M, Hoffman M, Yamada K. Self-organization and branching morphogenesis of primary salivary epithelial cells. Tissue Eng. 2007;13:721-35 pubmed
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Rivera Perez J, Diefes H, Magnuson T. A simple enzymatic method for parietal yolk sac removal in early postimplantation mouse embryos. Dev Dyn. 2007;236:489-93 pubmed
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Larsen M, Wei C, Yamada K. Cell and fibronectin dynamics during branching morphogenesis. J Cell Sci. 2006;119:3376-84 pubmed
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McCloskey K, Stice S, Nerem R. In vitro derivation and expansion of endothelial cells from embryonic stem cells. Methods Mol Biol. 2006;330:287-301 pubmed
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Janda E, Nevolo M, Lehmann K, Downward J, Beug H, Grieco M. Raf plus TGFbeta-dependent EMT is initiated by endocytosis and lysosomal degradation of E-cadherin. Oncogene. 2006;25:7117-30 pubmed
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Rivera Perez J, Magnuson T. Primitive streak formation in mice is preceded by localized activation of Brachyury and Wnt3. Dev Biol. 2005;288:363-71 pubmed
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Naim E, Bernstein A, Bertram J, Caruana G. Mutagenesis of the epithelial polarity gene, discs large 1, perturbs nephrogenesis in the developing mouse kidney. Kidney Int. 2005;68:955-65 pubmed
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Schuetz A, Rubin B, Goldblum J, Shehata B, Weiss S, Liu W, et al. Intercellular junctions in Ewing sarcoma/primitive neuroectodermal tumor: additional evidence of epithelial differentiation. Mod Pathol. 2005;18:1403-10 pubmed
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Ng E, Azzola L, Sourris K, Robb L, Stanley E, Elefanty A. The primitive streak gene Mixl1 is required for efficient haematopoiesis and BMP4-induced ventral mesoderm patterning in differentiating ES cells. Development. 2005;132:873-84 pubmed
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Shen X, Kramer R. Adhesion-mediated squamous cell carcinoma survival through ligand-independent activation of epidermal growth factor receptor. Am J Pathol. 2004;165:1315-29 pubmed
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Fouquet S, Lugo Martínez V, Faussat A, Renaud F, Cardot P, Chambaz J, et al. Early loss of E-cadherin from cell-cell contacts is involved in the onset of Anoikis in enterocytes. J Biol Chem. 2004;279:43061-9 pubmed
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Chang Rodriguez S, Ecker R, Stingl G, Elbe Bürger A. Autocrine IL-10 partially prevents differentiation of neonatal dendritic epidermal leukocytes into Langerhans cells. J Leukoc Biol. 2004;76:657-66 pubmed
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McCloskey K, Lyons I, Rao R, Stice S, Nerem R. Purified and proliferating endothelial cells derived and expanded in vitro from embryonic stem cells. Endothelium. 2003;10:329-36 pubmed
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McGuire J, Li Q, Parks W. Matrilysin (matrix metalloproteinase-7) mediates E-cadherin ectodomain shedding in injured lung epithelium. Am J Pathol. 2003;162:1831-43 pubmed
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Lallemand D, Curto M, Saotome I, Giovannini M, McClatchey A. NF2 deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions. Genes Dev. 2003;17:1090-100 pubmed
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Davis J, Duncan M, Robison W, Piatigorsky J. Requirement for Pax6 in corneal morphogenesis: a role in adhesion. J Cell Sci. 2003;116:2157-67 pubmed
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Tong W, Cortes U, Hande M, Ohgaki H, Cavalli L, Lansdorp P, et al. Synergistic role of Ku80 and poly(ADP-ribose) polymerase in suppressing chromosomal aberrations and liver cancer formation. Cancer Res. 2002;62:6990-6 pubmed
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Lopez T, Hanahan D. Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis. Cancer Cell. 2002;1:339-53 pubmed
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Carothers A, Melstrom K, Mueller J, Weyant M, Bertagnolli M. Progressive changes in adherens junction structure during intestinal adenoma formation in Apc mutant mice. J Biol Chem. 2001;276:39094-102 pubmed
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Feng C, Britton W, Palendira U, Groat N, Briscoe H, Bean A. Up-regulation of VCAM-1 and differential expansion of beta integrin-expressing T lymphocytes are associated with immunity to pulmonary Mycobacterium tuberculosis infection. J Immunol. 2000;164:4853-60 pubmed
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Ong A, Maines Bandiera S, Roskelley C, Auersperg N. An ovarian adenocarcinoma line derived from SV40/E-cadherin-transfected normal human ovarian surface epithelium. Int J Cancer. 2000;85:430-7 pubmed
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Anderson R, Fassler R, Georges Labouesse E, Hynes R, Bader B, Kreidberg J, et al. Mouse primordial germ cells lacking beta1 integrins enter the germline but fail to migrate normally to the gonads. Development. 1999;126:1655-64 pubmed
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  • 免疫沉淀; 小鼠; 图 1
  • 免疫印迹; 小鼠; 图 1
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产品信息
产品类型 :
抗体
产品名称 :
E钙粘蛋白单克隆抗体(ECCD-2)
目录# :
13-1900
规格 :
100微克
价格 :
美国455.00
克隆性 :
单克隆
纯度 :
离子交换层析
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Immunohistochemistry (Frozen): 10 µg/mL, Western Blot: 10 µg/mL
物种 :
小鼠
克隆 :
ECCD-2
抗体亚型 :
IgG2a
储存 :
4° C
描述 :
E-Cadherin (epithelial cadherin) is a classical cadherin from the cadherin (alcium dependent adhesion protein) superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. E-cadherin plays a central role in the growth and development of cells by controlling tissue architecture, and maintenance of tissue integrity. In humans, E-cadherin is encoded by the CDH1 gene present on chromosome 16. Studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.
免疫原 :
Mouse liver E-cadherin fragment.
格式 :
冻干
应用w/稀释 :
Immunohistochemistry (Frozen): 10 µg/mL, Western Blot: 10 µg/mL
别名 :
AA960649; ARC-1; cadherin 1; cadherin 1, E-cadherin (epithelial); cadherin 1, epithelial; cadherin 1, type 1; cadherin 1, type 1, E-cadherin (epithelial); cadherin e; cadherin-1; cadherin-E; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324; CDH1; CDHE; cell adhesion molecule; cell-CAM 120/80; ECAD; E-cad; E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3; Ecadherin; E-cadherin; E-cadherin 1; E-Cadherin phospho; E-cadherin precursor; Epithelial cadherin; hab; half baked; LCAM; L-CAM; phospho cadherin 1; phospho E-Cadherin; phospho LCAM; phospho S838; phospho UVO; S840; S840 E-Cadherin; Ser840; Ser840 E-Cadherin; Um; UVO; Uvomorulin
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
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http://www.thermo.com.cn
1084193588
公司总部: 美国