产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
钙粘蛋白P单克隆抗体(PCD-1)
目录 :
13-2000Z
规格 :
100微克
价格 :
449美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
PCD-1
反应物种 :
仓鼠, 人类, 小鼠,
应用 :
免疫印迹, 免疫组化, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 24
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 牛; 图 9b
Domke L, Franke W. The cell-cell junctions of mammalian testes: II. The lamellar smooth muscle monolayer cells of the peritubular wall are laterally connected by vertical adherens junctions-a novel architectonic cell-cell junction system. Cell Tissue Res. 2019;375:451-482 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 7d
  • 免疫组化-石蜡切片; 小鼠; 图 4c
  • 免疫印迹; 小鼠; 图 5c
Mescher M, Jeong P, Knapp S, Rübsam M, Saynisch M, Kranen M, et al. The epidermal polarity protein Par3 is a non-cell autonomous suppressor of malignant melanoma. J Exp Med. 2017;214:339-358 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 5
Iwai Takekoshi L, Ramos A, Schaler A, Weinreb S, Blazeski R, Mason C. Retinal pigment epithelial integrity is compromised in the developing albino mouse retina. J Comp Neurol. 2016;524:3696-3716 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:400; 图 2c
Tomann P, Paus R, Millar S, Scheidereit C, Schmidt Ullrich R. Lhx2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth. Development. 2016;143:1512-22 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:1000; 图 2
Biehs B, Hu J, Strauli N, Sangiorgi E, Jung H, Heber R, et al. BMI1 represses Ink4a/Arf and Hox genes to regulate stem cells in the rodent incisor. Nat Cell Biol. 2013;15:846-52 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 10 ug/ml; 图 6
Nagao K, Zhu J, Heneghan M, Hanson J, Morasso M, Tessarollo L, et al. Abnormal placental development and early embryonic lethality in EpCAM-null mice. PLoS ONE. 2009;4:e8543 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 2
Shimomura Y, Wajid M, Shapiro L, Christiano A. P-cadherin is a p63 target gene with a crucial role in the developing human limb bud and hair follicle. Development. 2008;135:743-53 pubmed 出版商
  • 流式细胞仪; 小鼠
Jia D, DaJusta D, Foty R. Tissue surface tensions guide in vitro self-assembly of rodent pancreatic islet cells. Dev Dyn. 2007;236:2039-49 pubmed
  • 免疫组化; 小鼠
Kashiwagi M, Morgan B, Georgopoulos K. The chromatin remodeler Mi-2beta is required for establishment of the basal epidermis and normal differentiation of its progeny. Development. 2007;134:1571-82 pubmed
  • 免疫组化; 小鼠
Akins M, Benson D, Greer C. Cadherin expression in the developing mouse olfactory system. J Comp Neurol. 2007;501:483-97 pubmed
  • 流式细胞仪; 小鼠
Duguay D, Foty R, Steinberg M. Cadherin-mediated cell adhesion and tissue segregation: qualitative and quantitative determinants. Dev Biol. 2003;253:309-23 pubmed
  • 免疫组化; 小鼠
Dahl U, Sjödin A, Larue L, Radice G, Cajander S, Takeichi M, et al. Genetic dissection of cadherin function during nephrogenesis. Mol Cell Biol. 2002;22:1474-87 pubmed
  • 免疫印迹; 小鼠
Scholl F, Gamallo C, Quintanilla M. Ectopic expression of PA2.26 antigen in epidermal keratinocytes leads to destabilization of adherens junctions and malignant progression. Lab Invest. 2000;80:1749-59 pubmed
  • 免疫组化; 小鼠; 1:200
Danjo Y, Gipson I. Actin 'purse string' filaments are anchored by E-cadherin-mediated adherens junctions at the leading edge of the epithelial wound, providing coordinated cell movement. J Cell Sci. 1998;111 ( Pt 22):3323-32 pubmed
Li K, Jain P, He C, Eun F, Kang S, Tumbar T. Skin vasculature and hair follicle cross-talking associated with stem cell activation and tissue homeostasis. elife. 2019;8: pubmed 出版商
Cohen J, Raviv S, Adir O, Padmanabhan K, Soffer A, Luxenburg C. The Wave complex controls epidermal morphogenesis and proliferation by suppressing Wnt-Sox9 signaling. J Cell Biol. 2019;218:1390-1406 pubmed 出版商
Miroshnikova Y, Le H, Schneider D, Thalheim T, Rübsam M, Bremicker N, et al. Adhesion forces and cortical tension couple cell proliferation and differentiation to drive epidermal stratification. Nat Cell Biol. 2018;20:69-80 pubmed 出版商
Grudzien Nogalska E, Reed B, Rhoads R. CPEB1 promotes differentiation and suppresses EMT in mammary epithelial cells. J Cell Sci. 2014;127:2326-38 pubmed 出版商
Veniaminova N, Vagnozzi A, Kopinke D, Do T, Murtaugh L, Maillard I, et al. Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration. Development. 2013;140:4870-80 pubmed 出版商
Rico M, Mukherjee A, Konieczkowski M, Bruggeman L, Miller R, Khan S, et al. WT1-interacting protein and ZO-1 translocate into podocyte nuclei after puromycin aminonucleoside treatment. Am J Physiol Renal Physiol. 2005;289:F431-41 pubmed
Tinkle C, Lechler T, Pasolli H, Fuchs E. Conditional targeting of E-cadherin in skin: insights into hyperproliferative and degenerative responses. Proc Natl Acad Sci U S A. 2004;101:552-7 pubmed
Liu G, Kaw B, Kurfis J, Rahmanuddin S, Kanwar Y, Chugh S. Neph1 and nephrin interaction in the slit diaphragm is an important determinant of glomerular permeability. J Clin Invest. 2003;112:209-21 pubmed
Jamora C, DasGupta R, Kocieniewski P, Fuchs E. Links between signal transduction, transcription and adhesion in epithelial bud development. Nature. 2003;422:317-22 pubmed
Takeichi M. The cadherins: cell-cell adhesion molecules controlling animal morphogenesis. Development. 1988;102:639-55 pubmed
产品信息
产品类型 :
抗体
产品名称 :
钙粘蛋白P单克隆抗体(PCD-1)
目录# :
13-2000Z
规格 :
100微克
价格 :
449美元
克隆性 :
单克隆
纯度 :
离子交换层析
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Immunohistochemistry (Frozen): Assay Dependent, Inhibition Assays: 60 µg/mL, Western Blot: 10 µg/mL
物种 :
小鼠
克隆 :
PCD-1
抗体亚型 :
IgG2a
储存 :
4° C
描述 :
P-cadherin, also known as Cadherin-3, is a Type 1 cadherin protein that belongs to the cadherin superfamily. Type 1 cadherins are single-pass transmembrane proteins that have 5 extracellular cadherin repeats and an intracellular domain that binds p120-catenin and beta-catenin. Cadherins are calcium-dependent cell-cell adhesion glycoproteins responsible for a range of processes including development, wound healing, cell-cell signaling, cell growth and differentiation. P-cadherin is expressed in human fetal structures, and in adult tissues such as the basal layer of the epidermis, breast, prostate, ovary, cervix, hair follicle, and corneal endothelium. P-cadherin expression has also been reported on embryonic stem cells, and stem cells of the normal mammary gland, and hair follicle. Overexpression of P-cadherin has been associated with poor prognosis in breast, prostate, ovary, colon, and stomach carcinomas. Mutations in CDH3 are associated with congential hypotrichosis with juvenile macular dystrophy.
免疫原 :
小鼠内胚层细胞株PSA5-E
格式 :
冻干
应用w/稀释 :
Immunohistochemistry (Frozen): Assay Dependent, Inhibition Assays: 60 µg/mL, Western Blot: 10 µg/mL
别名 :
AI385538; CADH3; cadherin 15, M-cadherin (myotubule); cadherin 3; cadherin 3, type 1, P-cadherin (placental); cadherin-3; Cadp; calcium-dependent adhesion protein, placental; CDH15; CDH3; CDHP; HJMD; PCAD; P-cadherin; Placental cadherin; Placental-cadherin; RPE-specific cadherin
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国