产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
钙粘蛋白N单克隆抗体(NCD-2)
目录 :
13-2100
规格 :
100微克
价格 :
美国459
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
NCD-2
反应物种 :
仓鼠, 日本人鹌鹑, 人类, 小鼠, 鸡, 非洲爪蛙
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 抑制或激活实验
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 16
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 鸡; 1:200; 图 2
  • 免疫印迹; 鸡; 1:2000; 图 5
Herrera A, Saade M, Menendez A, Marti E, Pons S. Sustained Wnt/?-catenin signalling causes neuroepithelial aberrations through the accumulation of aPKC at the apical pole. Nat Commun. 2014;5:4168 pubmed 出版商
  • 免疫印迹; 人类; 图 1
  • 免疫印迹; 仓鼠; 图 1
  • 免疫细胞化学; 鸡; 图 2
BRUSES J. Cell surface localization of ?3?4 nicotinic acetylcholine receptors is regulated by N-cadherin homotypic binding and actomyosin contractility. PLoS ONE. 2013;8:e62435 pubmed 出版商
  • 抑制或激活实验; 日本人鹌鹑
Romeih M, Cakstina I, Zile M. Retinoic acid is a negative physiological regulator of N-cadherin during early avian heart morphogenesis. Dev Growth Differ. 2009;51:753-67 pubmed 出版商
  • 免疫组化; 鸡; 图 5
Marrs G, Theisen C, BRUSES J. N-cadherin modulates voltage activated calcium influx via RhoA, p120-catenin, and myosin-actin interaction. Mol Cell Neurosci. 2009;40:390-400 pubmed 出版商
  • 免疫组化-石蜡切片; 鸡; 5 ug/ml; 图 1
Warchol M. Characterization of supporting cell phenotype in the avian inner ear: implications for sensory regeneration. Hear Res. 2007;227:11-8 pubmed
  • 免疫细胞化学; 小鼠
Foty R, Steinberg M. The differential adhesion hypothesis: a direct evaluation. Dev Biol. 2005;278:255-63 pubmed
  • 流式细胞仪; 鸡
Duguay D, Foty R, Steinberg M. Cadherin-mediated cell adhesion and tissue segregation: qualitative and quantitative determinants. Dev Biol. 2003;253:309-23 pubmed
  • 免疫组化; 小鼠
Mahlapuu M, Ormestad M, Enerback S, Carlsson P. The forkhead transcription factor Foxf1 is required for differentiation of extra-embryonic and lateral plate mesoderm. Development. 2001;128:155-66 pubmed
He Z, Lei S, Liang F, Tan L, Zhang W, Xie L, et al. Low-Dose Albendazole Inhibits Epithelial-Mesenchymal Transition of Melanoma Cells by Enhancing Phosphorylated GSK-3β/Tyr216 Accumulation. J Oncol. 2021;2021:4475192 pubmed 出版商
Herrera A, Menendez A, Torroba B, Ochoa A, Pons S. Dbnl and β-catenin promote pro-N-cadherin processing to maintain apico-basal polarity. J Cell Biol. 2021;220: pubmed 出版商
Liu J, Rao Y, Cheung M, Hui M, Wu M, Chan L, et al. Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration. Nat Commun. 2017;8:1185 pubmed 出版商
Theveneau E, Marchant L, Kuriyama S, Gull M, Moepps B, Parsons M, et al. Collective chemotaxis requires contact-dependent cell polarity. Dev Cell. 2010;19:39-53 pubmed 出版商
Ciesiolka M, Delvaeye M, Van Imschoot G, Verschuere V, McCrea P, van Roy F, et al. p120 catenin is required for morphogenetic movements involved in the formation of the eyes and the craniofacial skeleton in Xenopus. J Cell Sci. 2004;117:4325-39 pubmed
Robinson E, Zazzali K, Corbett S, Foty R. Alpha5beta1 integrin mediates strong tissue cohesion. J Cell Sci. 2003;116:377-86 pubmed
Ryan P, Foty R, Kohn J, Steinberg M. Tissue spreading on implantable substrates is a competitive outcome of cell-cell vs. cell-substratum adhesivity. Proc Natl Acad Sci U S A. 2001;98:4323-7 pubmed
Hirano S, Kimoto N, Shimoyama Y, Hirohashi S, Takeichi M. Identification of a neural alpha-catenin as a key regulator of cadherin function and multicellular organization. Cell. 1992;70:293-301 pubmed
产品信息
产品类型 :
抗体
产品名称 :
钙粘蛋白N单克隆抗体(NCD-2)
目录# :
13-2100
规格 :
100微克
价格 :
美国459
克隆性 :
单克隆
纯度 :
纯化
宿主 :
大鼠
反应物种 :
鸡, 非洲爪蛙
应用 :
Immunofluorescence: Assay Dependent, Immunohistochemistry (Frozen): 10 µg/mL, Inhibition Assays: 100 µg/mL, Western Blot: 1-10 µg/mL
物种 :
鸡, 非洲爪蛙
克隆 :
NCD-2
抗体亚型 :
IgG2a
储存 :
4° C
描述 :
N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin's function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin. Further, N-cadherin is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry.
免疫原 :
Neuronal tissue of chick embryos.
格式 :
冻干
应用w/稀释 :
Immunofluorescence: Assay Dependent, Immunohistochemistry (Frozen): 10 µg/mL, Inhibition Assays: 100 µg/mL, Western Blot: 1-10 µg/mL
别名 :
bib; cadherin 2; cadherin 2 L homeolog; cadherin 2 type 1 N-cadherin (neuronal); cadherin 2, neuronal; cadherin 2, type 1; cadherin 2, type 1, N-cadherin (neuronal); cadherin 2, type 1, N-cadherin (neuronal) L homeolog; cadherin 2, type 1, N-cadherin a (neuronal); Cadherin2; cadherin-2; Cadherin-2A; Cadherin-N; calcium-dependent adhesion protein, neuronal; CD325; cdh2; cdh2.L; cdh2a; cdh2-a; cdh2-b; CDHN; cdhn-a; CDw325; CDw325 antigen; cell adhesion molecule; glass onion; glo; I79_014914; labyrinth; LOC100344571; lyr; NCAD; N-Cad; N-cadherin; N-cadherin 1; N-cadherin A; N-cadherin precursor; N-cadherin-2; Neural cadherin; neural cadherin A; Neural cadherin-2; neural-cadherin; pac; Parachute; wu:fb47h04; XELAEV_18031953mg; ZNCAD
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国