产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
增殖细胞核抗原单克隆抗体(PC10), 生物素
目录 :
13-3940
规格 :
100微克
价格 :
425美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
生物素
克隆名称 :
PC10
反应物种 :
酿酒酵母S288C, 人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 10
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 小鼠; 1:300
Li X, Nadauld L, Ootani A, Corney D, Pai R, Gevaert O, et al. Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture. Nat Med. 2014;20:769-77 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 5
Das M, Garlick D, Greiner D, Davis R. The role of JNK in the development of hepatocellular carcinoma. Genes Dev. 2011;25:634-45 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:10; 图 1
Sayi A, Kohler E, Hitzler I, Arnold I, Schwendener R, Rehrauer H, et al. The CD4+ T cell-mediated IFN-gamma response to Helicobacter infection is essential for clearance and determines gastric cancer risk. J Immunol. 2009;182:7085-101 pubmed 出版商
  • 免疫组化; 小鼠
Nesslein L, Melton K, Ikegami M, Na C, Wert S, Rice W, et al. Partial SP-B deficiency perturbs lung function and causes air space abnormalities. Am J Physiol Lung Cell Mol Physiol. 2005;288:L1154-61 pubmed
  • 免疫组化-石蜡切片; 小鼠
Piechocki M, Lonardo F, Ensley J, Nguyen T, Kim H, Yoo G. Anticancer activity of docetaxel in murine salivary gland carcinoma. Clin Cancer Res. 2002;8:870-7 pubmed
Girnius N, Edwards Y, Garlick D, Davis R. The cJUN NH2-terminal kinase (JNK) signaling pathway promotes genome stability and prevents tumor initiation. elife. 2018;7: pubmed 出版商
Girnius N, Davis R. JNK Promotes Epithelial Cell Anoikis by Transcriptional and Post-translational Regulation of BH3-Only Proteins. Cell Rep. 2017;21:1910-1921 pubmed 出版商
Foster K, Liu Z, Nail C, Li X, Fitzgerald T, Bailey S, et al. Induction of KLF4 in basal keratinocytes blocks the proliferation-differentiation switch and initiates squamous epithelial dysplasia. Oncogene. 2005;24:1491-500 pubmed
Kramer B, Kramer S, Ikegami M, Jobe A. Injury, inflammation, and remodeling in fetal sheep lung after intra-amniotic endotoxin. Am J Physiol Lung Cell Mol Physiol. 2002;283:L452-9 pubmed
Datta K, Sundberg C, Karumanchi S, Mukhopadhyay D. The 104-123 amino acid sequence of the beta-domain of von Hippel-Lindau gene product is sufficient to inhibit renal tumor growth and invasion. Cancer Res. 2001;61:1768-75 pubmed
产品信息
产品类型 :
抗体
产品名称 :
增殖细胞核抗原单克隆抗体(PC10), 生物素
目录# :
13-3940
规格 :
100微克
价格 :
425美元
克隆性 :
单克隆
纯度 :
纯化
宿主 :
小鼠
反应物种 :
Human, Insect, Mouse, Non-human primate, Rat, Yeast
应用 :
Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: 1:1000
物种 :
Human, Insect, Mouse, Non-human primate, Rat, Yeast
克隆 :
PC10
抗体亚型 :
IgG2a
储存 :
4° C
描述 :
PCNA (polymerase delta auxiliary protein) is essential for DNA replication and is involved in DNA excision and mismatch repair pathways. PCNA binds to the CDK inhibitor p21, the structure-specific endonucleases Fen1 and XPG, and DNA cytosine 5-methyltransferase (MCMT). PCNA is a potentially useful marker of cells with proliferative potential and for identifying the proliferation status of tumor tissue (i.e. relevant to prognosis). PCNA is a marker for cells in early G1 phase and S phase of the cell cycle. PCNA is found in the nucleus and is a cofactor of DNA polymerase delta, and acts as a homotrimer and helps increase the processing of leading strand synthesis during DNA replication. In response to DNA damage, PCNA is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for PCNA. Pseudogenes of PCNA have been described on chromosome 4 and on the X chromosome.
免疫原 :
Rat recombinant PCNA polypeptides.
格式 :
液体
应用w/稀释 :
Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: 1:1000
别名 :
ATLD2; cb16; cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; hypothetical protein LOC515499; LOC100339381; MGC8367; PCNA; pcna protein; Pcna/cyclin; PCNAR; POL30; proliferating cell nuclear antigen; proliferating cell nuclear antigen-like; wu:fa28e03; wu:fb36g03; YBR0811; YBR088C
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国