产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IgM Monoclonal Antibody (II/41), Biotin, eBioscience™
目录 :
13-5790-85
规格 :
500微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
生物素
克隆名称 :
II/41
应用 :
免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 30
参考文献 |
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Ikawa T, Masuda K, Endo T, Endo M, Isono K, Koseki Y, et al. Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of the B-lineage program. Genes Dev. 2016;30:2475-2485 pubmed
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Ledesma Soto Y, Blanco Favela F, Fuentes Panana E, Tesoro Cruz E, Hernández González R, Arriaga Pizano L, et al. Increased levels of prolactin receptor expression correlate with the early onset of lupus symptoms and increased numbers of transitional-1 B cells after prolactin treatment. BMC Immunol. 2012;13:11 pubmed 出版商
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Bai L, Chen Y, He Y, Dai X, Lin X, Wen R, et al. Phospholipase Cgamma2 contributes to light-chain gene activation and receptor editing. Mol Cell Biol. 2007;27:5957-67 pubmed
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Savitsky D, Calame K. B-1 B lymphocytes require Blimp-1 for immunoglobulin secretion. J Exp Med. 2006;203:2305-14 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
IgM Monoclonal Antibody (II/41), Biotin, eBioscience™
目录# :
13-5790-85
规格 :
500微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.25 µg/test, Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent
物种 :
小鼠
克隆 :
II/41
抗体亚型 :
IgG2a, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
IgM (Immunoglobulin M) is expressed intracellularly during the early stages of B lymphopoiesis, and then on the surface of more mature B cells in the bone marrow and peripheral B cells. The isotype of a primary antibody and its application can result in background staining. Primary antibody background noise can be caused by binding to Fc receptors on target cells; by non-specific interactions with cellular proteins, carbohydrates, and lipids; or by cell autofluorescence. Isotype control antibodies can act as negative controls to help differentiate non-specific background signal from specific antibody signal because they have no relevant specificity to a target antigen. While isotype controls are most commonly used in flow cytometry, they are also useful in other applications such as chromatin immunoprecipitation (ChIP), immunohistochemistry, and gel shifts. Isotype controls should match with the primary antibody species and isotype so that the level of specific staining by the primary antibody may be accurately determined. If using directly labeled primary antibodies, the isotype control works best if conjugated with the same label as the test antibody.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.25 µg/test, Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent
别名 :
AGM1; AI326478; Igh6; Igh-6; Ighm; Igh-M; Igm; immunoglobulin heavy constant mu; MU; muH; VH
更多信息或购买 :
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