产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CD309 (FLK1) Monoclonal Antibody (Avas12a1), Biotin, eBioscience™
目录 :
13-5821-81
规格 :
50微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
生物素
克隆名称 :
Avas12a1
反应物种 :
小鼠
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 59
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 1:100; 图 1l
Chiapparo G, Lin X, Lescroart F, Chabab S, Paulissen C, Pitisci L, et al. Mesp1 controls the speed, polarity, and directionality of cardiovascular progenitor migration. J Cell Biol. 2016;213:463-77 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1
Goode D, Obier N, Vijayabaskar M, Lie A Ling M, Lilly A, Hannah R, et al. Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and Differentiation. Dev Cell. 2016;36:572-87 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:125
Zhang H, Nieves J, Fraser S, Isern J, Douvaras P, Papatsenko D, et al. Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm. Stem Cells. 2014;32:191-203 pubmed 出版商
Chagraoui H, Kristiansen M, Ruiz J, Serra Barros A, Richter J, Hall Ponsele E, et al. SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells. Nat Commun. 2018;9:5375 pubmed 出版商
Bergiers I, Andrews T, Vargel Bölükbaşı Ö, Buness A, Janosz E, Lopez Anguita N, et al. Single-cell transcriptomics reveals a new dynamical function of transcription factors during embryonic hematopoiesis. elife. 2018;7: pubmed 出版商
Murray L, Habiel D, Hohmann M, Camelo A, Shang H, Zhou Y, et al. Antifibrotic role of vascular endothelial growth factor in pulmonary fibrosis. JCI Insight. 2017;2: pubmed 出版商
Ogura S, Kurata K, Hattori Y, Takase H, Ishiguro Oonuma T, Hwang Y, et al. Sustained inflammation after pericyte depletion induces irreversible blood-retina barrier breakdown. JCI Insight. 2017;2:e90905 pubmed 出版商
Illendula A, Gilmour J, Grembecka J, Tirumala V, Boulton A, Kuntimaddi A, et al. Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers. EBioMedicine. 2016;8:117-131 pubmed 出版商
Fleury M, Eliades A, Carlsson P, Lacaud G, Kouskoff V. FOXF1 inhibits hematopoietic lineage commitment during early mesoderm specification. Development. 2015;142:3307-20 pubmed 出版商
Wu L, Wary K, REVSKOY S, Gao X, Tsang K, Komarova Y, et al. Histone Demethylases KDM4A and KDM4C Regulate Differentiation of Embryonic Stem Cells to Endothelial Cells. Stem Cell Reports. 2015;5:10-21 pubmed 出版商
Regha K, Assi S, Tsoulaki O, Gilmour J, Lacaud G, Bonifer C. Developmental-stage-dependent transcriptional response to leukaemic oncogene expression. Nat Commun. 2015;6:7203 pubmed 出版商
Wang J, Xiao J, Wen D, Wu X, Mao Z, Zhang J, et al. Endothelial cell-anchored tissue factor pathway inhibitor regulates tumor metastasis to the lung in mice. Mol Carcinog. 2016;55:882-96 pubmed 出版商
Liu H, Chen Y, Yan F, Han X, Wu J, Liu X, et al. Ultrasound molecular imaging of vascular endothelial growth factor receptor 2 expression for endometrial receptivity evaluation. Theranostics. 2015;5:206-17 pubmed 出版商
Yamamizu K, Schlessinger D, Ko M. SOX9 accelerates ESC differentiation to three germ layer lineages by repressing SOX2 expression through P21 (WAF1/CIP1). Development. 2014;141:4254-66 pubmed 出版商
Ubil E, Duan J, Pillai I, Rosa Garrido M, Wu Y, Bargiacchi F, et al. Mesenchymal-endothelial transition contributes to cardiac neovascularization. Nature. 2014;514:585-90 pubmed 出版商
Cho S, Park J, Heo H, Park S, Song S, Kim I, et al. Dual modulation of the mitochondrial permeability transition pore and redox signaling synergistically promotes cardiomyocyte differentiation from pluripotent stem cells. J Am Heart Assoc. 2014;3:e000693 pubmed 出版商
Shi X, Richard J, Zirbes K, Gong W, Lin G, Kyba M, et al. Cooperative interaction of Etv2 and Gata2 regulates the development of endothelial and hematopoietic lineages. Dev Biol. 2014;389:208-18 pubmed 出版商
Agudo J, Ruzo A, Tung N, Salmon H, Leboeuf M, Hashimoto D, et al. The miR-126-VEGFR2 axis controls the innate response to pathogen-associated nucleic acids. Nat Immunol. 2014;15:54-62 pubmed 出版商
Mancini M, Greco A, Salvatore G, Liuzzi R, Di Maro G, Vergara E, et al. Imaging of thyroid tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice. BMC Med Imaging. 2013;13:31 pubmed 出版商
Oda M, Kumaki Y, Shigeta M, Jakt L, Matsuoka C, Yamagiwa A, et al. DNA methylation restricts lineage-specific functions of transcription factor Gata4 during embryonic stem cell differentiation. PLoS Genet. 2013;9:e1003574 pubmed 出版商
Craft A, Ahmed N, Rockel J, Baht G, Alman B, Kandel R, et al. Specification of chondrocytes and cartilage tissues from embryonic stem cells. Development. 2013;140:2597-610 pubmed 出版商
Rasmussen T, Martin C, Walter C, Shi X, Perlingeiro R, Koyano Nakagawa N, et al. Etv2 rescues Flk1 mutant embryoid bodies. Genesis. 2013;51:471-80 pubmed 出版商
Roehrich M, Spicher A, Milano G, Vassalli G. Characterization of cardiac-resident progenitor cells expressing high aldehyde dehydrogenase activity. Biomed Res Int. 2013;2013:503047 pubmed 出版商
Behrens A, Iacovino M, Lohr J, Ren Y, Zierold C, Harvey R, et al. Nkx2-5 mediates differential cardiac differentiation through interaction with Hoxa10. Stem Cells Dev. 2013;22:2211-20 pubmed 出版商
Rasmussen T, Shi X, Wallis A, Kweon J, Zirbes K, Koyano Nakagawa N, et al. VEGF/Flk1 signaling cascade transactivates Etv2 gene expression. PLoS ONE. 2012;7:e50103 pubmed 出版商
Lichtinger M, Ingram R, Hannah R, Müller D, Clarke D, Assi S, et al. RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis. EMBO J. 2012;31:4318-33 pubmed 出版商
Sountoulidis A, Stavropoulos A, Giaglis S, Apostolou E, Monteiro R, Chuva de Sousa Lopes S, et al. Activation of the canonical bone morphogenetic protein (BMP) pathway during lung morphogenesis and adult lung tissue repair. PLoS ONE. 2012;7:e41460 pubmed 出版商
Joo H, Choi D, Lim J, Park J, Lee S, Song S, et al. ROCK suppression promotes differentiation and expansion of endothelial cells from embryonic stem cell-derived Flk1(+) mesodermal precursor cells. Blood. 2012;120:2733-44 pubmed
Warram J, Sorace A, Saini R, Borovjagin A, Hoyt K, Zinn K. Systemic delivery of a breast cancer-detecting adenovirus using targeted microbubbles. Cancer Gene Ther. 2012;19:545-52 pubmed 出版商
Koyano Nakagawa N, Kweon J, Iacovino M, Shi X, Rasmussen T, Borges L, et al. Etv2 is expressed in the yolk sac hematopoietic and endothelial progenitors and regulates Lmo2 gene expression. Stem Cells. 2012;30:1611-23 pubmed 出版商
Jayaraman P, Parikh F, López Rivera E, Hailemichael Y, Clark A, Ma G, et al. Tumor-expressed inducible nitric oxide synthase controls induction of functional myeloid-derived suppressor cells through modulation of vascular endothelial growth factor release. J Immunol. 2012;188:5365-76 pubmed 出版商
van den Ameele J, Tiberi L, Bondue A, Paulissen C, Herpoel A, Iacovino M, et al. Eomesodermin induces Mesp1 expression and cardiac differentiation from embryonic stem cells in the absence of Activin. EMBO Rep. 2012;13:355-62 pubmed 出版商
Nobuhisa I, Yamasaki S, Ramadan A, Taga T. CD45(low)c-Kit(high) cells have hematopoietic properties in the mouse aorta-gonad-mesonephros region. Exp Cell Res. 2012;318:705-15 pubmed 出版商
Beck B, Driessens G, Goossens S, Youssef K, Kuchnio A, Caauwe A, et al. A vascular niche and a VEGF-Nrp1 loop regulate the initiation and stemness of skin tumours. Nature. 2011;478:399-403 pubmed 出版商
Gill J, Langer E, Lindsley R, Cai M, Murphy T, Murphy K. Snail promotes the cell-autonomous generation of Flk1(+) endothelial cells through the repression of the microRNA-200 family. Stem Cells Dev. 2012;21:167-76 pubmed 出版商
Warram J, Sorace A, Saini R, Umphrey H, Zinn K, Hoyt K. A triple-targeted ultrasound contrast agent provides improved localization to tumor vasculature. J Ultrasound Med. 2011;30:921-31 pubmed
Joo H, Kim H, Park S, Cho H, Kim H, Lim D, et al. Angiopoietin-1 promotes endothelial differentiation from embryonic stem cells and induced pluripotent stem cells. Blood. 2011;118:2094-104 pubmed 出版商
Yu H, Qin H, He F, Wang L, Fu W, Liu D, et al. Canonical notch pathway protects hepatocytes from ischemia/reperfusion injury in mice by repressing reactive oxygen species production through JAK2/STAT3 signaling. Hepatology. 2011;54:979-88 pubmed 出版商
Gill J, Langer E, Lindsley R, Cai M, Murphy T, Kyba M, et al. Snail and the microRNA-200 family act in opposition to regulate epithelial-to-mesenchymal transition and germ layer fate restriction in differentiating ESCs. Stem Cells. 2011;29:764-76 pubmed 出版商
Bondue A, Tännler S, Chiapparo G, Chabab S, Ramialison M, Paulissen C, et al. Defining the earliest step of cardiovascular progenitor specification during embryonic stem cell differentiation. J Cell Biol. 2011;192:751-65 pubmed 出版商
Schenke Layland K, Nsair A, Van Handel B, Angelis E, Gluck J, Votteler M, et al. Recapitulation of the embryonic cardiovascular progenitor cell niche. Biomaterials. 2011;32:2748-56 pubmed 出版商
Ma M, Ding S, Lundqvist A, San H, Fang F, Konoplyannikov M, et al. Major histocompatibility complex-I expression on embryonic stem cell-derived vascular progenitor cells is critical for syngeneic transplant survival. Stem Cells. 2010;28:1465-75 pubmed 出版商
Morris L, Klanke C, Lang S, Pokall S, Maldonado A, Vuletin J, et al. Characterization of endothelial progenitor cells mobilization following cutaneous wounding. Wound Repair Regen. 2010;18:383-90 pubmed 出版商
Paz H, Lynch M, Bogue C, Gasson J. The homeobox gene Hhex regulates the earliest stages of definitive hematopoiesis. Blood. 2010;116:1254-62 pubmed 出版商
Reijmers R, Vondenhoff M, Roozendaal R, Kuil A, Li J, Spaargaren M, et al. Impaired lymphoid organ development in mice lacking the heparan sulfate modifying enzyme glucuronyl C5-epimerase. J Immunol. 2010;184:3656-64 pubmed 出版商
Carmi Y, Voronov E, Dotan S, Lahat N, Rahat M, Fogel M, et al. The role of macrophage-derived IL-1 in induction and maintenance of angiogenesis. J Immunol. 2009;183:4705-14 pubmed 出版商
Zhang H, Fraser S, Papazoglu C, Hoatlin M, Baron M. Transcriptional activation by the Mixl1 homeodomain protein in differentiating mouse embryonic stem cells. Stem Cells. 2009;27:2884-95 pubmed 出版商
Utikal J, Polo J, Stadtfeld M, Maherali N, Kulalert W, Walsh R, et al. Immortalization eliminates a roadblock during cellular reprogramming into iPS cells. Nature. 2009;460:1145-8 pubmed 出版商
Senju S, Haruta M, Matsunaga Y, Fukushima S, Ikeda T, Takahashi K, et al. Characterization of dendritic cells and macrophages generated by directed differentiation from mouse induced pluripotent stem cells. Stem Cells. 2009;27:1021-31 pubmed 出版商
Vondenhoff M, Greuter M, Goverse G, Elewaut D, Dewint P, Ware C, et al. LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen. J Immunol. 2009;182:5439-45 pubmed 出版商
Asahina K, Tsai S, Li P, Ishii M, Maxson R, Sucov H, et al. Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development. Hepatology. 2009;49:998-1011 pubmed 出版商
Vondenhoff M, van de Pavert S, Dillard M, Greuter M, Goverse G, Oliver G, et al. Lymph sacs are not required for the initiation of lymph node formation. Development. 2009;136:29-34 pubmed 出版商
Bosnakovski D, Xu Z, Li W, Thet S, Cleaver O, Perlingeiro R, et al. Prospective isolation of skeletal muscle stem cells with a Pax7 reporter. Stem Cells. 2008;26:3194-204 pubmed 出版商
Sheng H, Wang Y, Jin Y, Zhang Q, Zhang Y, Wang L, et al. A critical role of IFNgamma in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1. Cell Res. 2008;18:846-57 pubmed 出版商
Willmann J, Paulmurugan R, Chen K, Gheysens O, Rodriguez Porcel M, Lutz A, et al. US imaging of tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice. Radiology. 2008;246:508-18 pubmed 出版商
Lyshchik A, Fleischer A, Huamani J, Hallahan D, Brissova M, Gore J. Molecular imaging of vascular endothelial growth factor receptor 2 expression using targeted contrast-enhanced high-frequency ultrasonography. J Ultrasound Med. 2007;26:1575-86 pubmed
Bone H, Welham M. Phosphoinositide 3-kinase signalling regulates early development and developmental haemopoiesis. J Cell Sci. 2007;120:1752-62 pubmed
Lindsley R, Gill J, Kyba M, Murphy T, Murphy K. Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm. Development. 2006;133:3787-96 pubmed
Kano M, Morishita Y, Iwata C, Iwasaka S, Watabe T, Ouchi Y, et al. VEGF-A and FGF-2 synergistically promote neoangiogenesis through enhancement of endogenous PDGF-B-PDGFRbeta signaling. J Cell Sci. 2005;118:3759-68 pubmed
产品信息
产品类型 :
抗体
产品名称 :
CD309 (FLK1) Monoclonal Antibody (Avas12a1), Biotin, eBioscience™
目录# :
13-5821-81
规格 :
50微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
Flow Cytometry: 0.5 µg/test
物种 :
小鼠
克隆 :
Avas12a1
抗体亚型 :
IgG2a, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of this gene are implicated in infantile capillary hemangiomas.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.5 µg/test
别名 :
6130401C07; CD309; CD309 antigen; fetal liver kinase 1; fetal liver kinase-1; FLK1; Flk-1; FLK1 kinase insert domain receptor (a type III receptor tyrosine kinase) (VEGF receptor 2); FLK1 kinase insert domain receptor (VEGF receptor 2); flk-1 type VEGF receptor; KDR; kinase insert domain protein receptor; kinase insert domain receptor; kinase insert domain receptor (a type III receptor tyrosine kinase); kinase NYK; Krd-1; Ly73; protein-tyrosine kinase receptor flk-1; sCD309; soluble CD309; soluble vascular endothelial growth factor receptor 2; soluble VEGFR 2; soluble VEGFR2; sVEGFR-2; tyrosine kinase growth factor receptor; vascular endotheial growth factor 2; vascular endothelial growth factor receptor 2; vascular endothelial growth factor receptor- 2; vascular endothelial growth factor receptor-2; vascular endothelial growth factor receptor-3; VEGF R2; VEGF receptor-2; VEGFR; VEGFR2; VEGFR-2
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国