产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
转铁蛋白受体单克隆抗体(H68.4)
目录 :
13-6800
规格 :
100微克
价格 :
美国402
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
H68.4
反应物种 :
African green monkey, cabbage looper, 中国人仓鼠, 仓鼠, 人类, 小鼠, 大鼠, , , , pigs , brewer's yeast, , 国内马
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 抑制或激活实验
更多信息或购买 :
文章摘录数: 646
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 1a
Ashok A, Chaudhary S, Wise A, Rana N, McDonald D, Kritikos A, et al. Release of Iron-Loaded Ferritin in Sodium Iodate-Induced Model of Age Related Macular Degeneration: An In-Vitro and In-Vivo Study. Antioxidants (Basel). 2021;10: pubmed 出版商
  • 免疫印迹; 人类; 1:3000; 图 3a
Zuo Y, Xie J, Li X, Li Y, Thirupathi A, Zhang J, et al. Ferritinophagy-Mediated Ferroptosis Involved in Paraquat-Induced Neurotoxicity of Dopaminergic Neurons: Implication for Neurotoxicity in PD. Oxid Med Cell Longev. 2021;2021:9961628 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3d
Cerny O, Godlee C, Tocci R, Cross N, Shi H, Williamson J, et al. CD97 stabilises the immunological synapse between dendritic cells and T cells and is targeted for degradation by the Salmonella effector SteD. PLoS Pathog. 2021;17:e1009771 pubmed 出版商
  • 免疫印迹; 人类; 图 6c
Moissoglu K, Stueland M, Gasparski A, Wang T, Jenkins L, Hastings M, et al. RNA localization and co-translational interactions control RAB13 GTPase function and cell migration. EMBO J. 2020;39:e104958 pubmed 出版商
  • 免疫组化-冰冻切片; pigs ; 图 5b
Mazgaj R, Szudzik M, Lipiński P, Jończy A, Smuda E, Kamyczek M, et al. Effect of Oral Supplementation of Healthy Pregnant Sows with Sucrosomial Ferric Pyrophosphate on Maternal Iron Status and Hepatic Iron Stores in Newborn Piglets. Animals (Basel). 2020;10: pubmed 出版商
  • 免疫印迹; 小鼠; 图 s3b
Kapralov A, Yang Q, Dar H, Tyurina Y, Anthonymuthu T, Kim R, et al. Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death. Nat Chem Biol. 2020;16:278-290 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3d
Wang Y, Maeda Y, Liu Y, Takada Y, Ninomiya A, Hirata T, et al. Cross-talks of glycosylphosphatidylinositol biosynthesis with glycosphingolipid biosynthesis and ER-associated degradation. Nat Commun. 2020;11:860 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 5c
  • 免疫印迹; 小鼠; 1:2000; 图 1d
Bendriem R, Singh S, Aleem A, Antonetti D, Ross M. Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3a
Luteijn R, Zaver S, Gowen B, Wyman S, Garelis N, Onia L, et al. SLC19A1 transports immunoreactive cyclic dinucleotides. Nature. 2019;573:434-438 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2c
  • 免疫印迹; 人类; 1:5000; 图 s2c
Marques P, Nyegaard S, Collins R, Troise F, Freeman S, Trimble W, et al. Multimerization and Retention of the Scavenger Receptor SR-B1 in the Plasma Membrane. Dev Cell. 2019;: pubmed 出版商
  • 免疫印迹; 小鼠; 图 1e
Schaffer T, Smith J, Cook E, Phan T, Margolis S. PKCε Inhibits Neuronal Dendritic Spine Development through Dual Phosphorylation of Ephexin5. Cell Rep. 2018;25:2470-2483.e8 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1h
Schwartz A, Das N, Ramakrishnan S, Jain C, Jurkovic M, Wu J, et al. Hepatic hepcidin/intestinal HIF-2α axis maintains iron absorption during iron deficiency and overload. J Clin Invest. 2019;129:336-348 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s13a
Gerber T, Murawala P, Knapp D, Masselink W, Schuez M, Hermann S, et al. Single-cell analysis uncovers convergence of cell identities during axolotl limb regeneration. Science. 2018;362: pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 s4i
Gut G, Herrmann M, Pelkmans L. Multiplexed protein maps link subcellular organization to cellular states. Science. 2018;361: pubmed 出版商
  • 免疫印迹; 人类; 图 s1c
Almeida Souza L, Frank R, García Nafría J, Colussi A, Gunawardana N, Johnson C, et al. A Flat BAR Protein Promotes Actin Polymerization at the Base of Clathrin-Coated Pits. Cell. 2018;174:325-337.e14 pubmed 出版商
  • 免疫组化; 牛; 图 1a
  • 免疫印迹; 牛; 1:1000; 图 3a
Ashok A, Karmakar S, Chandel R, Ravikumar R, Dalal S, Kong Q, et al. Prion protein modulates iron transport in the anterior segment: Implications for ocular iron homeostasis and prion transmission. Exp Eye Res. 2018;175:1-13 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:100; 图 1b
  • 免疫印迹; 大鼠; 1:1000; 图 s1b
Zhang L, Zhang P, Wang G, Zhang H, Zhang Y, Yu Y, et al. Ras and Rap Signal Bidirectional Synaptic Plasticity via Distinct Subcellular Microdomains. Neuron. 2018;98:783-800.e4 pubmed 出版商
  • 免疫印迹; 人类; 图 5b
Mukadam A, Breusegem S, Seaman M. Analysis of novel endosome-to-Golgi retrieval genes reveals a role for PLD3 in regulating endosomal protein sorting and amyloid precursor protein processing. Cell Mol Life Sci. 2018;75:2613-2625 pubmed 出版商
  • 免疫组化; 人类; 图 1b
Licon Munoz Y, Michel V, Fordyce C, Parra K. F-actin reorganization by V-ATPase inhibition in prostate cancer. Biol Open. 2017;6:1734-1744 pubmed 出版商
  • 免疫印迹; 人类; 1:200
Patwardhan A, Bardin S, Miserey Lenkei S, Larue L, Goud B, Raposo G, et al. Routing of the RAB6 secretory pathway towards the lysosome related organelle of melanocytes. Nat Commun. 2017;8:15835 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 3a
Mrowczynski O, Madhankumar A, Slagle Webb B, Lee S, Zacharia B, Connor J. HFE genotype affects exosome phenotype in cancer. Biochim Biophys Acta Gen Subj. 2017;1861:1921-1928 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s2c
Allison R, Edgar J, Pearson G, Rizo T, Newton T, Günther S, et al. Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegia. J Cell Biol. 2017;216:1337-1355 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 5a
Roy N, Pacini G, Berlioz Torrent C, Janvier K. Characterization of E3 ligases involved in lysosomal sorting of the HIV-1 restriction factor BST2. J Cell Sci. 2017;130:1596-1611 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4a
Larson C, Heinzen R. High-Content Imaging Reveals Expansion of the Endosomal Compartment during Coxiella burnetii Parasitophorous Vacuole Maturation. Front Cell Infect Microbiol. 2017;7:48 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Ingrassia R, Memo M, Garavaglia B. Ferrous Iron Up-regulation in Fibroblasts of Patients with Beta Propeller Protein-Associated Neurodegeneration (BPAN). Front Genet. 2017;8:18 pubmed 出版商
  • 免疫印迹; 大鼠; 图 1b
Santiago Valtierra F, Mateos M, Aveldaño M, Oresti G. Sphingomyelins and ceramides with VLCPUFAs are excluded from low-density raft-like domains in differentiating spermatogenic cells. J Lipid Res. 2017;58:529-542 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6d
  • 免疫印迹; 人类; 图 5d
Nelson J, Koenis D, Scheij S, Cook E, Moeton M, Santos A, et al. EEPD1 Is a Novel LXR Target Gene in Macrophages Which Regulates ABCA1 Abundance and Cholesterol Efflux. Arterioscler Thromb Vasc Biol. 2017;37:423-432 pubmed 出版商
  • 免疫印迹; 人类; 图 7f
Cianciola N, Chung S, Manor D, Carlin C. Adenovirus Modulates Toll-Like Receptor 4 Signaling by Reprogramming ORP1L-VAP Protein Contacts for Cholesterol Transport from Endosomes to the Endoplasmic Reticulum. J Virol. 2017;91: pubmed 出版商
  • 免疫组化; 人类; 1:1000; 图 4d
Bruurs L, Zwakenberg S, van der Net M, Zwartkruis F, Bos J. A Two-Tiered Mechanism Enables Localized Cdc42 Signaling during Enterocyte Polarization. Mol Cell Biol. 2017;37: pubmed 出版商
  • 免疫印迹; 小鼠; 图 1c
Yamauchi T, Nishiyama M, Moroishi T, Kawamura A, Nakayama K. FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells. Mol Cell Biol. 2017;37: pubmed 出版商
  • 免疫印迹; 人类; 1:2500; 图 2d
Rychtarčíková Z, Lettlova S, Tomkova V, Korenkova V, Langerova L, Simonova E, et al. Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism. Oncotarget. 2017;8:6376-6398 pubmed 出版商
  • 免疫细胞化学; 人类; 1:300; 图 4d
  • 免疫印迹; 人类; 1:500; 图 3a
Wymant J, Hiscox S, Westwell A, Urbé S, Clague M, Jones A. The Role of BCA2 in the Endocytic Trafficking of EGFR and Significance as a Prognostic Biomarker in Cancer. J Cancer. 2016;7:2388-2407 pubmed
  • 免疫细胞化学; 小鼠; 1:100; 图 4a
Tafteh R, Abraham L, Seo D, Lu H, Gold M, Chou K. Real-time 3D stabilization of a super-resolution microscope using an electrically tunable lens. Opt Express. 2016;24:22959-22970 pubmed 出版商
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Horniblow R, Henesy D, Iqbal T, Tselepis C. Modulation of iron transport, metabolism and reactive oxygen status by quercetin-iron complexes in vitro. Mol Nutr Food Res. 2017;61: pubmed 出版商
  • 免疫印迹; 小鼠; 图 2a
Lian G, Dettenhofer M, Lu J, Downing M, Chenn A, Wong T, et al. Filamin A- and formin 2-dependent endocytosis regulates proliferation via the canonical Wnt pathway. Development. 2016;143:4509-4520 pubmed
  • 免疫细胞化学; 人类; 图 1
  • 免疫印迹; 人类; 图 5d
Tanaka Y, Ono N, Shima T, Tanaka G, Katoh Y, Nakayama K, et al. The phospholipid flippase ATP9A is required for the recycling pathway from the endosomes to the plasma membrane. Mol Biol Cell. 2016;27:3883-3893 pubmed
  • 免疫印迹; 人类; 1:1000; 图 3b
Hu Z, Wang J, Yu D, Soon J, de Kleijn D, Foo R, et al. Aberrant Splicing Promotes Proteasomal Degradation of L-type CaV1.2 Calcium Channels by Competitive Binding for CaVβ Subunits in Cardiac Hypertrophy. Sci Rep. 2016;6:35247 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 2
Gasperini L, Meneghetti E, Legname G, Benetti F. In Absence of the Cellular Prion Protein, Alterations in Copper Metabolism and Copper-Dependent Oxidase Activity Affect Iron Distribution. Front Neurosci. 2016;10:437 pubmed
  • 免疫组化; 人类; 1:200; 图 1b
Ng O. Iron, microbiota and colorectal cancer. Wien Med Wochenschr. 2016;166:431-436 pubmed
  • 免疫细胞化学; 牛; 1:100; 图 1c
Hersom M, Helms H, Pretzer N, Goldeman C, Jensen A, Severin G, et al. Transferrin receptor expression and role in transendothelial transport of transferrin in cultured brain endothelial monolayers. Mol Cell Neurosci. 2016;76:59-67 pubmed 出版商
  • 免疫印迹; 大鼠; 图 3a
Sierra Valdez F, Ruiz Suárez J, Delint Ramirez I. Pentobarbital modifies the lipid raft-protein interaction: A first clue about the anesthesia mechanism on NMDA and GABAA receptors. Biochim Biophys Acta. 2016;1858:2603-2610 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4c
Xue H, Chen D, Zhong Y, Zhou Z, Fang S, Li M, et al. Deferoxamine ameliorates hepatosteatosis via several mechanisms in ob/ob mice. Ann N Y Acad Sci. 2016;1375:52-65 pubmed 出版商
  • 免疫细胞化学; 人类; 10 ug/ml; 图 6a
Egea Jimenez A, Gallardo R, Garcia Pino A, Ivarsson Y, Wawrzyniak A, Kashyap R, et al. Frizzled 7 and PIP2 binding by syntenin PDZ2 domain supports Frizzled 7 trafficking and signalling. Nat Commun. 2016;7:12101 pubmed 出版商
  • 免疫组化; 小鼠; 1:400; 图 1a
  • 免疫印迹; 小鼠; 图 6b
Lei R, Zhang K, Liu K, Shao X, Ding Z, Wang F, et al. Transferrin receptor facilitates TGF-β and BMP signaling activation to control craniofacial morphogenesis. Cell Death Dis. 2016;7:e2282 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 1
  • 免疫印迹; 小鼠; 1:2000; 图 2
  • 免疫细胞化学; 人类; 图 1
  • 免疫印迹; 人类; 1:2000; 图 5
Baksi S, Tripathi A, Singh N. Alpha-synuclein modulates retinal iron homeostasis by facilitating the uptake of transferrin-bound iron: Implications for visual manifestations of Parkinson's disease. Free Radic Biol Med. 2016;97:292-306 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3
  • 免疫印迹; 大鼠; 1:1000; 图 3
Ito F, Nishiyama T, Shi L, Mori M, Hirayama T, Nagasawa H, et al. Contrasting intra- and extracellular distribution of catalytic ferrous iron in ovalbumin-induced peritonitis. Biochem Biophys Res Commun. 2016;476:600-606 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 6
Russell S, Puttick D, Sawyer A, Potter D, Mague S, Carlezon W, et al. Nucleus Accumbens AMPA Receptors Are Necessary for Morphine-Withdrawal-Induced Negative-Affective States in Rats. J Neurosci. 2016;36:5748-62 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Stroh M, Winter M, Swerdlow R, McCarson K, Zhu H. Loss of NCB5OR in the cerebellum disturbs iron pathways, potentiates behavioral abnormalities, and exacerbates harmaline-induced tremor in mice. Metab Brain Dis. 2016;31:951-64 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 s4
  • 免疫印迹; 小鼠; 1:1000; 图 s7
Fusté N, Fernández Hernández R, Cemeli T, Mirantes C, Pedraza N, Rafel M, et al. Cytoplasmic cyclin D1 regulates cell invasion and metastasis through the phosphorylation of paxillin. Nat Commun. 2016;7:11581 pubmed 出版商
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Hernaez B, Guerra M, Salas M, Andres G. African Swine Fever Virus Undergoes Outer Envelope Disruption, Capsid Disassembly and Inner Envelope Fusion before Core Release from Multivesicular Endosomes. PLoS Pathog. 2016;12:e1005595 pubmed 出版商
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Kurkinen K, Marttinen M, Turner L, Natunen T, Mäkinen P, Haapalinna F, et al. SEPT8 modulates ?-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1. J Cell Sci. 2016;129:2224-38 pubmed 出版商
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Corcelle Termeau E, Vindeløv S, Hämälistö S, Mograbi B, Keldsbo A, Bräsen J, et al. Excess sphingomyelin disturbs ATG9A trafficking and autophagosome closure. Autophagy. 2016;12:833-49 pubmed 出版商
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Gandolfi B, Alamri S, Darby W, Adhikari B, Lattimer J, Malik R, et al. A dominant TRPV4 variant underlies osteochondrodysplasia in Scottish fold cats. Osteoarthritis Cartilage. 2016;24:1441-50 pubmed 出版商
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Guo C, Hao L, Yang Z, Chai R, Zhang S, Gu Y, et al. Deferoxamine-mediated up-regulation of HIF-1α prevents dopaminergic neuronal death via the activation of MAPK family proteins in MPTP-treated mice. Exp Neurol. 2016;280:13-23 pubmed 出版商
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Choi J, Kim J, Won Y, Uhm J, Park B, Lee Y. The potential of deferasirox as a novel therapeutic modality in gastric cancer. World J Surg Oncol. 2016;14:77 pubmed 出版商
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Jhaveri D, Kim M, Thompson E, Huang L, Sharma R, Klein A, et al. Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer. Cancer Immunol Res. 2016;4:225-33 pubmed 出版商
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Lyons M, Chen L, Deng J, Finn C, Pfenning A, Sabhlok A, et al. The transcription factor calcium-response factor limits NMDA receptor-dependent transcription in the developing brain. J Neurochem. 2016;137:164-76 pubmed 出版商
  • 流式细胞仪; 人类; 1:200
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Ketel K, Krauss M, Nicot A, Puchkov D, Wieffer M, Müller R, et al. A phosphoinositide conversion mechanism for exit from endosomes. Nature. 2016;529:408-12 pubmed 出版商
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Zhao Y, Feresin R, Falcon Perez J, Salazar G. Differential Targeting of SLC30A10/ZnT10 Heterodimers to Endolysosomal Compartments Modulates EGF-Induced MEK/ERK1/2 Activity. Traffic. 2016;17:267-88 pubmed 出版商
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Yamaguchi T, Lu C, Ida L, Yanagisawa K, Usukura J, Cheng J, et al. ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1. Nat Commun. 2016;7:10060 pubmed 出版商
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Nelson J, Cook E, Loregger A, Hoeksema M, Scheij S, Kovacevic I, et al. Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake. J Biol Chem. 2016;291:4813-25 pubmed 出版商
  • 免疫细胞化学; 大鼠; 图 1
Fan S, Numata Y, Numata M. Endosomal Na+/H+ exchanger NHE5 influences MET recycling and cell migration. Mol Biol Cell. 2016;27:702-15 pubmed 出版商
  • 免疫细胞化学; 仓鼠; 1:200; 图 6
  • 免疫印迹; 仓鼠; 图 8
Chen A, Kim S, Shepardson N, Patel S, Hong S, Selkoe D. Physical and functional interaction between the α- and γ-secretases: A new model of regulated intramembrane proteolysis. J Cell Biol. 2015;211:1157-76 pubmed 出版商
  • 免疫印迹; cabbage looper; 图 5
Patrone M, Coroadinha A, Teixeira A, Alves P. Palmitoylation Strengthens Cholesterol-dependent Multimerization and Fusion Activity of Human Cytomegalovirus Glycoprotein B (gB). J Biol Chem. 2016;291:4711-22 pubmed 出版商
  • 免疫印迹; 人类; 图 2d
Jabara H, Boyden S, Chou J, Ramesh N, Massaad M, Benson H, et al. A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency. Nat Genet. 2016;48:74-8 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 9
Natunen T, Takalo M, Kemppainen S, Leskelä S, Marttinen M, Kurkinen K, et al. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models. Neurobiol Dis. 2016;85:187-205 pubmed 出版商
  • 免疫细胞化学; African green monkey; 图 2
Billcliff P, Noakes C, Mehta Z, Yan G, Mak L, Woscholski R, et al. OCRL1 engages with the F-BAR protein pacsin 2 to promote biogenesis of membrane-trafficking intermediates. Mol Biol Cell. 2016;27:90-107 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:500; 图 3
  • 免疫印迹; 人类; 1:2000; 图 4
Mori M, Ito F, Shi L, Wang Y, Ishida C, Hattori Y, et al. Ovarian endometriosis-associated stromal cells reveal persistently high affinity for iron. Redox Biol. 2015;6:578-586 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100; 图 3
Covarrubias Pinto A, Moll P, Solís Maldonado M, Acuña A, Riveros A, Miró M, et al. Beyond the redox imbalance: Oxidative stress contributes to an impaired GLUT3 modulation in Huntington's disease. Free Radic Biol Med. 2015;89:1085-96 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 s1
Bruurs L, Donker L, Zwakenberg S, Zwartkruis F, Begthel H, Knisely A, et al. ATP8B1-mediated spatial organization of Cdc42 signaling maintains singularity during enterocyte polarization. J Cell Biol. 2015;210:1055-63 pubmed 出版商
  • 免疫印迹; 人类
Sirohi K, Kumari A, Radha V, Swarup G. A Glaucoma-Associated Variant of Optineurin, M98K, Activates Tbk1 to Enhance Autophagosome Formation and Retinal Cell Death Dependent on Ser177 Phosphorylation of Optineurin. PLoS ONE. 2015;10:e0138289 pubmed 出版商
  • 免疫印迹; 大鼠
Vanderwerf S, Buck D, Wilmarth P, Sears L, David L, Morton D, et al. Role for Rab10 in Methamphetamine-Induced Behavior. PLoS ONE. 2015;10:e0136167 pubmed 出版商
  • 免疫印迹; 大鼠; 1:200
Sun L, Yan M, Hu X, Peng L, Che H, Bao Y, et al. MicroRNA-9 induces defective trafficking of Nav1.1 and Nav1.2 by targeting Navβ2 protein coding region in rat with chronic brain hypoperfusion. Mol Neurodegener. 2015;10:36 pubmed 出版商
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David J, Stas J, Schmitt N, Bocksteins E. Auxiliary KCNE subunits modulate both homotetrameric Kv2.1 and heterotetrameric Kv2.1/Kv6.4 channels. Sci Rep. 2015;5:12813 pubmed 出版商
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Ferreira J, Schmidt J, Rio P, Águas R, Rooyakkers A, Li K, et al. GluN2B-Containing NMDA Receptors Regulate AMPA Receptor Traffic through Anchoring of the Synaptic Proteasome. J Neurosci. 2015;35:8462-79 pubmed 出版商
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Jang D, Kwon H, Jeong K, Lee J, Pak Y. Essential role of flotillin-1 palmitoylation in the intracellular localization and signaling function of IGF-1 receptor. J Cell Sci. 2015;128:2179-90 pubmed 出版商
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Chung J, Bauer D, Ghamari A, Nizzi C, Deck K, Kingsley P, et al. The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability. Sci Signal. 2015;8:ra34 pubmed 出版商
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Dayer C, Stamenkovic I. Recruitment of Matrix Metalloproteinase-9 (MMP-9) to the Fibroblast Cell Surface by Lysyl Hydroxylase 3 (LH3) Triggers Transforming Growth Factor-β (TGF-β) Activation and Fibroblast Differentiation. J Biol Chem. 2015;290:13763-78 pubmed 出版商
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Chen J, Tibroni N, Sauter D, Galaski J, Miura T, Alter G, et al. Modest attenuation of HIV-1 Vpu alleles derived from elite controller plasma. PLoS ONE. 2015;10:e0120434 pubmed 出版商
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Liu C, Tan F, Xiao Z, Dawe G. Amyloid precursor protein enhances Nav1.6 sodium channel cell surface expression. J Biol Chem. 2015;290:12048-57 pubmed 出版商
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Haakenson J, Khokhlatchev A, Choi Y, Linton S, Zhang P, Zaki P, et al. Lysosomal degradation of CD44 mediates ceramide nanoliposome-induced anoikis and diminished extravasation in metastatic carcinoma cells. J Biol Chem. 2015;290:8632-43 pubmed 出版商
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Alghamdi R, O Reilly P, Lu C, Gomes J, Lagace T, Basak A. LDL-R promoting activity of peptides derived from human PCSK9 catalytic domain (153-421): design, synthesis and biochemical evaluation. Eur J Med Chem. 2015;92:890-907 pubmed 出版商
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Dongiovanni P, Lanti C, Gatti S, Rametta R, Recalcati S, Maggioni M, et al. High fat diet subverts hepatocellular iron uptake determining dysmetabolic iron overload. PLoS ONE. 2015;10:e0116855 pubmed 出版商
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Pettingill P, Kramer H, Coebergh J, Pettingill R, Maxwell S, Nibber A, et al. Antibodies to GABAA receptor α1 and γ2 subunits: clinical and serologic characterization. Neurology. 2015;84:1233-41 pubmed 出版商
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Lee S, Uchida Y, Wang J, Matsudaira T, Nakagawa T, Kishimoto T, et al. Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase. EMBO J. 2015;34:669-88 pubmed 出版商
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Van de Laar E, Clifford M, Hasenoeder S, Kim B, Wang D, Lee S, et al. Cell surface marker profiling of human tracheal basal cells reveals distinct subpopulations, identifies MST1/MSP as a mitogenic signal, and identifies new biomarkers for lung squamous cell carcinomas. Respir Res. 2014;15:160 pubmed 出版商
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Zacherl S, La Venuta G, Muller H, Wegehingel S, Dimou E, Sehr P, et al. A direct role for ATP1A1 in unconventional secretion of fibroblast growth factor 2. J Biol Chem. 2015;290:3654-65 pubmed 出版商
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Ng D, Humphries J, Byron A, Millon Frémillon A, Humphries M. Microtubule-dependent modulation of adhesion complex composition. PLoS ONE. 2014;9:e115213 pubmed 出版商
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Ram S, Kim D, Ober R, Ward E. The level of HER2 expression is a predictor of antibody-HER2 trafficking behavior in cancer cells. MAbs. 2014;6:1211-9 pubmed 出版商
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Guo L, Alekseev O, Li Y, Song Y, Dunaief J. Iron increases APP translation and amyloid-beta production in the retina. Exp Eye Res. 2014;129:31-7 pubmed 出版商
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de Carvalho J, de Castro R, da Silva E, Silveira P, da Silva Januário M, Arruda E, et al. Nef neutralizes the ability of exosomes from CD4+ T cells to act as decoys during HIV-1 infection. PLoS ONE. 2014;9:e113691 pubmed 出版商
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Udensi U, Tackett A, Byrum S, Avaritt N, Sengupta D, Moreland L, et al. Proteomics-Based Identification of Differentially Abundant Proteins from Human Keratinocytes Exposed to Arsenic Trioxide. J Proteomics Bioinform. 2014;7:166-178 pubmed
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Siggs O, Grieve A, Xu H, Bambrough P, Christova Y, Freeman M. Genetic interaction implicates iRhom2 in the regulation of EGF receptor signalling in mice. Biol Open. 2014;3:1151-7 pubmed 出版商
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Cao C, Thomas C, Insogna K, O Brien K. Duodenal absorption and tissue utilization of dietary heme and nonheme iron differ in rats. J Nutr. 2014;144:1710-7 pubmed 出版商
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Takatsu H, Tanaka G, Segawa K, Suzuki J, Nagata S, Nakayama K, et al. Phospholipid flippase activities and substrate specificities of human type IV P-type ATPases localized to the plasma membrane. J Biol Chem. 2014;289:33543-56 pubmed 出版商
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Zhang Y, Wang N, Su P, Lu J, Wang Y. Disruption of dopamine D1 receptor phosphorylation at serine 421 attenuates cocaine-induced behaviors in mice. Neurosci Bull. 2014;30:1025-35 pubmed 出版商
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Orchard Webb D, Lee T, Cook G, Blair G. CUB domain containing protein 1 (CDCP1) modulates adhesion and motility in colon cancer cells. BMC Cancer. 2014;14:754 pubmed 出版商
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Shi Z, Shi F, Wang Y, Sheftel A, Nie G, Zhao Y, et al. Mitochondrial ferritin, a new target for inhibiting neuronal tumor cell proliferation. Cell Mol Life Sci. 2015;72:983-97 pubmed 出版商
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Pance A, Morrissey Wettey F, Craig H, Downing A, Talbot R, Jackson A. SDF-1 chemokine signalling modulates the apoptotic responses to iron deprivation of clathrin-depleted DT40 cells. PLoS ONE. 2014;9:e106278 pubmed 出版商
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Luteijn R, Hoelen H, Kruse E, van Leeuwen W, Grootens J, Horst D, et al. Cowpox virus protein CPXV012 eludes CTLs by blocking ATP binding to TAP. J Immunol. 2014;193:1578-89 pubmed 出版商
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Tseng H, Thorausch N, Ziegler T, Meves A, Fassler R, Böttcher R. Sorting nexin 31 binds multiple ? integrin cytoplasmic domains and regulates ?1 integrin surface levels and stability. J Mol Biol. 2014;426:3180-3194 pubmed 出版商
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Singh A, Kan C, Shende V, Dong B, Liu J. A novel posttranscriptional mechanism for dietary cholesterol-mediated suppression of liver LDL receptor expression. J Lipid Res. 2014;55:1397-407 pubmed 出版商
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Moroishi T, Yamauchi T, Nishiyama M, Nakayama K. HERC2 targets the iron regulator FBXL5 for degradation and modulates iron metabolism. J Biol Chem. 2014;289:16430-41 pubmed 出版商
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Thomas P, Cheng A, Colby C, Liu L, Patel C, Josephs L, et al. Localization and proteomic characterization of cholesterol-rich membrane microdomains in the inner ear. J Proteomics. 2014;103:178-93 pubmed 出版商
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Perdomini M, Belbellaa B, Monassier L, Reutenauer L, Messaddeq N, Cartier N, et al. Prevention and reversal of severe mitochondrial cardiomyopathy by gene therapy in a mouse model of Friedreich's ataxia. Nat Med. 2014;20:542-7 pubmed 出版商
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Satoh D, Hirose T, Harita Y, Daimon C, Harada T, Kurihara H, et al. aPKC? maintains the integrity of the glomerular slit diaphragm through trafficking of nephrin to the cell surface. J Biochem. 2014;156:115-28 pubmed 出版商
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Moissoglu K, Kiessling V, Wan C, Hoffman B, Norambuena A, Tamm L, et al. Regulation of Rac1 translocation and activation by membrane domains and their boundaries. J Cell Sci. 2014;127:2565-76 pubmed 出版商
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Sakane H, Horii Y, Nogami S, Kawano Y, Kaneko Kawano T, Shirataki H. ?-Taxilin interacts with sorting nexin 4 and participates in the recycling pathway of transferrin receptor. PLoS ONE. 2014;9:e93509 pubmed 出版商
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Montenegro M, Moral Naranjo M, Campoy F, Muñoz Delgado E, Vidal C. The lipid raft-bound alkaline phosphatase activity increases and the level of transcripts remains unaffected in liver of merosin-deficient LAMA2dy mouse. Chem Biol Interact. 2014;216:1-8 pubmed 出版商
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Ikeda Y, Ozono I, Tajima S, Imao M, Horinouchi Y, Izawa Ishizawa Y, et al. Iron chelation by deferoxamine prevents renal interstitial fibrosis in mice with unilateral ureteral obstruction. PLoS ONE. 2014;9:e89355 pubmed 出版商
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Follit J, San Agustin J, Jonassen J, Huang T, Rivera Perez J, Tremblay K, et al. Arf4 is required for Mammalian development but dispensable for ciliary assembly. PLoS Genet. 2014;10:e1004170 pubmed 出版商
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van Gent M, Braem S, de Jong A, Delagic N, Peeters J, Boer I, et al. Epstein-Barr virus large tegument protein BPLF1 contributes to innate immune evasion through interference with toll-like receptor signaling. PLoS Pathog. 2014;10:e1003960 pubmed 出版商
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Baumann T, Bergmann S, Schmidt Rose T, Max H, Martin A, Enthaler B, et al. Glutathione-conjugated sulfanylalkanols are substrates for ABCC11 and ?-glutamyl transferase 1: a potential new pathway for the formation of odorant precursors in the apocrine sweat gland. Exp Dermatol. 2014;23:247-52 pubmed 出版商
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Schneppenheim J, Hüttl S, Mentrup T, Lüllmann Rauch R, Rothaug M, Engelke M, et al. The intramembrane proteases signal Peptide peptidase-like 2a and 2b have distinct functions in vivo. Mol Cell Biol. 2014;34:1398-411 pubmed 出版商
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Bien Ly N, Yu Y, Bumbaca D, Elstrott J, Boswell C, Zhang Y, et al. Transferrin receptor (TfR) trafficking determines brain uptake of TfR antibody affinity variants. J Exp Med. 2014;211:233-44 pubmed 出版商
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Aida K, Hayashi H, Inamura K, Mizuno T, Sugiyama Y. Differential roles of ubiquitination in the degradation mechanism of cell surface-resident bile salt export pump and multidrug resistance-associated protein 2. Mol Pharmacol. 2014;85:482-91 pubmed 出版商
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Wang N, Su P, Zhang Y, Lu J, Xing B, Kang K, et al. Protein kinase D1-dependent phosphorylation of dopamine D1 receptor regulates cocaine-induced behavioral responses. Neuropsychopharmacology. 2014;39:1290-301 pubmed 出版商
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Even Desrumeaux K, Nevoltris D, Lavaut M, Alim K, Borg J, Audebert S, et al. Masked selection: a straightforward and flexible approach for the selection of binders against specific epitopes and differentially expressed proteins by phage display. Mol Cell Proteomics. 2014;13:653-65 pubmed 出版商
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Matsui T, Fukuda M. Methods of analysis of the membrane trafficking pathway from recycling endosomes to lysosomes. Methods Enzymol. 2014;534:195-206 pubmed 出版商
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Landry M, Champagne C, Boulanger M, Jetté A, Fuchs M, Dziengelewski C, et al. A functional interplay between the small GTPase Rab11a and mitochondria-shaping proteins regulates mitochondrial positioning and polarization of the actin cytoskeleton downstream of Src family kinases. J Biol Chem. 2014;289:2230-49 pubmed 出版商
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Veuthey T, Hoffmann D, Vaidya V, Wessling Resnick M. Impaired renal function and development in Belgrade rats. Am J Physiol Renal Physiol. 2014;306:F333-43 pubmed 出版商
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Gabriel L, Wu S, Kearney P, Bellve K, Standley C, Fogarty K, et al. Dopamine transporter endocytic trafficking in striatal dopaminergic neurons: differential dependence on dynamin and the actin cytoskeleton. J Neurosci. 2013;33:17836-46 pubmed 出版商
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Garrido Gil P, Rodriguez Pallares J, Dominguez Meijide A, Guerra M, Labandeira Garcia J. Brain angiotensin regulates iron homeostasis in dopaminergic neurons and microglial cells. Exp Neurol. 2013;250:384-96 pubmed 出版商
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Das U, Scott D, Ganguly A, Koo E, Tang Y, Roy S. Activity-induced convergence of APP and BACE-1 in acidic microdomains via an endocytosis-dependent pathway. Neuron. 2013;79:447-60 pubmed 出版商
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Tornieri K, Zlatic S, Mullin A, Werner E, Harrison R, L hernault S, et al. Vps33b pathogenic mutations preferentially affect VIPAS39/SPE-39-positive endosomes. Hum Mol Genet. 2013;22:5215-28 pubmed 出版商
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Bloomer S, Han O, Kregel K, Brown K. Altered expression of iron regulatory proteins with aging is associated with transient hepatic iron accumulation after environmental heat stress. Blood Cells Mol Dis. 2014;52:19-26 pubmed 出版商
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Byrne S, Buckett P, Kim J, Luo F, Sanford J, Chen J, et al. Ferristatin II promotes degradation of transferrin receptor-1 in vitro and in vivo. PLoS ONE. 2013;8:e70199 pubmed 出版商
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Marco S, Giralt A, Petrovic M, Pouladi M, Mart nez Turrillas R, Mart nez Hern ndez J, et al. Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models. Nat Med. 2013;19:1030-8 pubmed 出版商
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von Germar A, Barth K, Schwab W. Immunocytochemical and biochemical detection of the urokinase-type plasminogen activator receptor (uPAR) in the rat tooth germ and in lipid rafts of PMA-stimulated dental epithelial cells. Histochem Cell Biol. 2013;140:649-58 pubmed 出版商
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Mueller W, Schütz D, Nagel F, Schulz S, Stumm R. Hierarchical organization of multi-site phosphorylation at the CXCR4 C terminus. PLoS ONE. 2013;8:e64975 pubmed 出版商
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Ahn J, Truesdell P, Meens J, Kadish C, Yang X, Boag A, et al. Fer protein-tyrosine kinase promotes lung adenocarcinoma cell invasion and tumor metastasis. Mol Cancer Res. 2013;11:952-63 pubmed 出版商
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Sak M, Szymanska M, Bertelsen V, Hasmann M, Madshus I, Stang E. Pertuzumab counteracts the inhibitory effect of ErbB2 on degradation of ErbB3. Carcinogenesis. 2013;34:2031-8 pubmed 出版商
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Bol G, Raman V, van der Groep P, Vermeulen J, Patel A, van der Wall E, et al. Expression of the RNA helicase DDX3 and the hypoxia response in breast cancer. PLoS ONE. 2013;8:e63548 pubmed 出版商
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Boczek N, Best J, Tester D, Giudicessi J, Middha S, Evans J, et al. Exome sequencing and systems biology converge to identify novel mutations in the L-type calcium channel, CACNA1C, linked to autosomal dominant long QT syndrome. Circ Cardiovasc Genet. 2013;6:279-89 pubmed
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Kwon H, Lee J, Jeong K, Jang D, Pak Y. A novel actin cytoskeleton-dependent noncaveolar microdomain composed of homo-oligomeric caveolin-2 for activation of insulin signaling. Biochim Biophys Acta. 2013;1833:2176-89 pubmed 出版商
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Viswanathan J, Haapasalo A, Kurkinen K, Natunen T, Mäkinen P, Bertram L, et al. Ubiquilin-1 modulates ?-secretase-mediated ?-site cleavage in neuronal cells. Biochemistry. 2013;52:3899-912 pubmed 出版商
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Castillon G, Michon L, Watanabe R. Apical sorting of lysoGPI-anchored proteins occurs independent of association with detergent-resistant membranes but dependent on their N-glycosylation. Mol Biol Cell. 2013;24:2021-33 pubmed 出版商
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Holloway Z, Velayos Baeza A, Howell G, Levecque C, Ponnambalam S, Sztul E, et al. Trafficking of the Menkes copper transporter ATP7A is regulated by clathrin-, AP-2-, AP-1-, and Rab22-dependent steps. Mol Biol Cell. 2013;24:1735-48, S1-8 pubmed 出版商
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Duman J, Tzeng C, Tu Y, Munjal T, Schwechter B, Ho T, et al. The adhesion-GPCR BAI1 regulates synaptogenesis by controlling the recruitment of the Par3/Tiam1 polarity complex to synaptic sites. J Neurosci. 2013;33:6964-78 pubmed 出版商
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Caster A, Sztul E, Kahn R. A role for cargo in Arf-dependent adaptor recruitment. J Biol Chem. 2013;288:14788-804 pubmed 出版商
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Cone J, Chartoff E, Potter D, Ebner S, Roitman M. Prolonged high fat diet reduces dopamine reuptake without altering DAT gene expression. PLoS ONE. 2013;8:e58251 pubmed 出版商
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Murata Y, Constantine Paton M. Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway. J Neurosci. 2013;33:5040-52 pubmed 出版商
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Lane D, Chikhani S, Richardson V, Richardson D. Transferrin iron uptake is stimulated by ascorbate via an intracellular reductive mechanism. Biochim Biophys Acta. 2013;1833:1527-41 pubmed 出版商
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Martineau M, Shi T, Puyal J, Knolhoff A, Dulong J, Gasnier B, et al. Storage and uptake of D-serine into astrocytic synaptic-like vesicles specify gliotransmission. J Neurosci. 2013;33:3413-23 pubmed 出版商
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Stergiou L, Bauer M, Mair W, Bausch Fluck D, Drayman N, Wollscheid B, et al. Integrin-mediated signaling induced by simian virus 40 leads to transient uncoupling of cortical actin and the plasma membrane. PLoS ONE. 2013;8:e55799 pubmed 出版商
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Scotti E, Calamai M, Goulbourne C, Zhang L, Hong C, Lin R, et al. IDOL stimulates clathrin-independent endocytosis and multivesicular body-mediated lysosomal degradation of the low-density lipoprotein receptor. Mol Cell Biol. 2013;33:1503-14 pubmed 出版商
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Matsuoka H, Harada K, Nakamura J, Inoue M. Nerve growth factor-induced endocytosis of TWIK-related acid-sensitive K? 1 channels in adrenal medullary cells and PC12 cells. Pflugers Arch. 2013;465:1051-64 pubmed 出版商
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Sirohi K, Chalasani M, Sudhakar C, Kumari A, Radha V, Swarup G. M98K-OPTN induces transferrin receptor degradation and RAB12-mediated autophagic death in retinal ganglion cells. Autophagy. 2013;9:510-27 pubmed 出版商
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Dettmer U, Newman A, Luth E, Bartels T, Selkoe D. In vivo cross-linking reveals principally oligomeric forms of ?-synuclein and ?-synuclein in neurons and non-neural cells. J Biol Chem. 2013;288:6371-85 pubmed 出版商
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Yu Y, Suryo Rahmanto Y, Richardson D. Bp44mT: an orally active iron chelator of the thiosemicarbazone class with potent anti-tumour efficacy. Br J Pharmacol. 2012;165:148-66 pubmed 出版商
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Bijlmakers M, Kanneganti S, Barker J, Trembath R, Capon F. Functional analysis of the RNF114 psoriasis susceptibility gene implicates innate immune responses to double-stranded RNA in disease pathogenesis. Hum Mol Genet. 2011;20:3129-37 pubmed 出版商
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Malik I, Naz N, Sheikh N, Khan S, Moriconi F, Blaschke M, et al. Comparison of changes in gene expression of transferrin receptor-1 and other iron-regulatory proteins in rat liver and brain during acute-phase response. Cell Tissue Res. 2011;344:299-312 pubmed 出版商
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Zlatic S, Tornieri K, L hernault S, Faundez V. Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells. Mol Biol Cell. 2011;22:1699-715 pubmed 出版商
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Yu Y, Richardson D. Cellular iron depletion stimulates the JNK and p38 MAPK signaling transduction pathways, dissociation of ASK1-thioredoxin, and activation of ASK1. J Biol Chem. 2011;286:15413-27 pubmed 出版商
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Mostad E, Prohaska J. Glycosylphosphatidylinositol-linked ceruloplasmin is expressed in multiple rodent organs and is lower following dietary copper deficiency. Exp Biol Med (Maywood). 2011;236:298-308 pubmed 出版商
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Reyes Lopez M, Bermúdez Cruz R, Avila E, de la Garza M. Acetaldehyde/alcohol dehydrogenase-2 (EhADH2) and clathrin are involved in internalization of human transferrin by Entamoeba histolytica. Microbiology. 2011;157:209-19 pubmed 出版商
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Khirug S, Ahmad F, Puskarjov M, Afzalov R, Kaila K, Blaesse P. A single seizure episode leads to rapid functional activation of KCC2 in the neonatal rat hippocampus. J Neurosci. 2010;30:12028-35 pubmed 出版商
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Rolando M, Stefani C, Flatau G, Auberger P, Mettouchi A, Mhlanga M, et al. Transcriptome dysregulation by anthrax lethal toxin plays a key role in induction of human endothelial cell cytotoxicity. Cell Microbiol. 2010;12:891-905 pubmed 出版商
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Nitta T, Kuznetsov Y, McPherson A, Fan H. Murine leukemia virus glycosylated Gag (gPr80gag) facilitates interferon-sensitive virus release through lipid rafts. Proc Natl Acad Sci U S A. 2010;107:1190-5 pubmed 出版商
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Kerr M, Gasperini R, Gibbs M, Hou X, Shepherd C, Strickland D, et al. Inhibition of Abeta aggregation and neurotoxicity by the 39-kDa receptor-associated protein. J Neurochem. 2010;112:1199-209 pubmed 出版商
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Barrès C, Blanc L, Bette Bobillo P, Andre S, Mamoun R, Gabius H, et al. Galectin-5 is bound onto the surface of rat reticulocyte exosomes and modulates vesicle uptake by macrophages. Blood. 2010;115:696-705 pubmed 出版商
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Sarajärvi T, Haapasalo A, Viswanathan J, Mäkinen P, Laitinen M, Soininen H, et al. Down-regulation of seladin-1 increases BACE1 levels and activity through enhanced GGA3 depletion during apoptosis. J Biol Chem. 2009;284:34433-43 pubmed 出版商
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Ishikawa H, Ma Z, Barber G. STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity. Nature. 2009;461:788-92 pubmed 出版商
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Humphries J, Byron A, Bass M, Craig S, Pinney J, Knight D, et al. Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6. Sci Signal. 2009;2:ra51 pubmed 出版商
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Wu L, Derynck R. Essential role of TGF-beta signaling in glucose-induced cell hypertrophy. Dev Cell. 2009;17:35-48 pubmed 出版商
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Skinner A, O Neill S, Kurre P. Cellular microvesicle pathways can be targeted to transfer genetic information between non-immune cells. PLoS ONE. 2009;4:e6219 pubmed 出版商
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Roepstorff K, Grandal M, Henriksen L, Knudsen S, Lerdrup M, Grøvdal L, et al. Differential effects of EGFR ligands on endocytic sorting of the receptor. Traffic. 2009;10:1115-27 pubmed 出版商
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Salazar G, Falcon Perez J, Harrison R, Faundez V. SLC30A3 (ZnT3) oligomerization by dityrosine bonds regulates its subcellular localization and metal transport capacity. PLoS ONE. 2009;4:e5896 pubmed 出版商
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Liefhebber J, Brandt B, Broer R, Spaan W, van Leeuwen H. Hepatitis C virus NS4B carboxy terminal domain is a membrane binding domain. Virol J. 2009;6:62 pubmed 出版商
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Duan W, Zhang R, Guo Y, Jiang Y, Huang Y, Jiang H, et al. Nrf2 activity is lost in the spinal cord and its astrocytes of aged mice. In Vitro Cell Dev Biol Anim. 2009;45:388-97 pubmed 出版商
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Wang Y, Posner B, Balbis A. Compartmentalization of epidermal growth factor receptor in liver plasma membrane. J Cell Biochem. 2009;107:96-103 pubmed 出版商
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Rhee K, Wu S, Wu X, Huso D, Karim B, Franco A, et al. Induction of persistent colitis by a human commensal, enterotoxigenic Bacteroides fragilis, in wild-type C57BL/6 mice. Infect Immun. 2009;77:1708-18 pubmed 出版商
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Feldmann A, Winterstein C, White R, Trotter J, Krämer Albers E. Comprehensive analysis of expression, subcellular localization, and cognate pairing of SNARE proteins in oligodendrocytes. J Neurosci Res. 2009;87:1760-72 pubmed 出版商
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Youn P, Kim S, Ahn J, Kim Y, Park J, Ryu D. Regulation of iron metabolism-related genes in diethylnitrosamine-induced mouse liver tumors. Toxicol Lett. 2009;184:151-8 pubmed 出版商
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Persaud Sawin D, Lightcap S, Harry G. Isolation of rafts from mouse brain tissue by a detergent-free method. J Lipid Res. 2009;50:759-67 pubmed 出版商
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Witte V, Laffert B, Gintschel P, Krautkrämer E, Blume K, Fackler O, et al. Induction of HIV transcription by Nef involves Lck activation and protein kinase C theta raft recruitment leading to activation of ERK1/2 but not NF kappa B. J Immunol. 2008;181:8425-32 pubmed
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Kongkham P, Northcott P, Ra Y, Nakahara Y, Mainprize T, Croul S, et al. An epigenetic genome-wide screen identifies SPINT2 as a novel tumor suppressor gene in pediatric medulloblastoma. Cancer Res. 2008;68:9945-53 pubmed 出版商
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de Gassart A, Trentin B, Martin M, Hocquellet A, Bette Bobillo P, Mamoun R, et al. Exosomal sorting of the cytoplasmic domain of bovine leukemia virus TM Env protein. Cell Biol Int. 2009;33:36-48 pubmed 出版商
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Bergmann O, Mathahs M, Broadhurst K, Weydert J, Wilkinson N, Howe J, et al. Altered expression of iron regulatory genes in cirrhotic human livers: clues to the cause of hemosiderosis?. Lab Invest. 2008;88:1349-57 pubmed 出版商
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Persaud Sawin D, Banach L, Harry G. Raft aggregation with specific receptor recruitment is required for microglial phagocytosis of Abeta42. Glia. 2009;57:320-35 pubmed 出版商
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Lineberry N, Su L, Soares L, Fathman C. The single subunit transmembrane E3 ligase gene related to anergy in lymphocytes (GRAIL) captures and then ubiquitinates transmembrane proteins across the cell membrane. J Biol Chem. 2008;283:28497-505 pubmed 出版商
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Grimsey N, Han G, O Hara L, Rochford J, Carman G, Siniossoglou S. Temporal and spatial regulation of the phosphatidate phosphatases lipin 1 and 2. J Biol Chem. 2008;283:29166-74 pubmed 出版商
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Inoue H, Ha V, Prekeris R, Randazzo P. Arf GTPase-activating protein ASAP1 interacts with Rab11 effector FIP3 and regulates pericentrosomal localization of transferrin receptor-positive recycling endosome. Mol Biol Cell. 2008;19:4224-37 pubmed 出版商
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Roberts L, Black D, Raman C, Woodford K, Zhou M, Haggerty J, et al. Subcellular localization of transporters along the rat blood-brain barrier and blood-cerebral-spinal fluid barrier by in vivo biotinylation. Neuroscience. 2008;155:423-38 pubmed 出版商
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Lespagnol A, Duflaut D, Beekman C, Blanc L, Fiucci G, Marine J, et al. Exosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6/Steap3-null mice. Cell Death Differ. 2008;15:1723-33 pubmed 出版商
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Kamemura K, Ito A, Shimazu T, Matsuyama A, Maeda S, Yao T, et al. Effects of downregulated HDAC6 expression on the proliferation of lung cancer cells. Biochem Biophys Res Commun. 2008;374:84-9 pubmed 出版商
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Takahashi M, Shibutani M, Woo G, Inoue K, Fujimoto H, Igarashi K, et al. Cellular distributions of molecules with altered expression specific to the tumor promotion process from the early stage in a rat two-stage hepatocarcinogenesis model. Carcinogenesis. 2008;29:2218-26 pubmed 出版商
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Stehling O, Netz D, Niggemeyer B, Rösser R, Eisenstein R, Puccio H, et al. Human Nbp35 is essential for both cytosolic iron-sulfur protein assembly and iron homeostasis. Mol Cell Biol. 2008;28:5517-28 pubmed 出版商
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Zhang L, Lee J, Wilusz J, Wilusz C. The RNA-binding protein CUGBP1 regulates stability of tumor necrosis factor mRNA in muscle cells: implications for myotonic dystrophy. J Biol Chem. 2008;283:22457-63 pubmed 出版商
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Kolodziej A, Schulz S, Guyon A, Wu D, Pfeiffer M, Odemis V, et al. Tonic activation of CXC chemokine receptor 4 in immature granule cells supports neurogenesis in the adult dentate gyrus. J Neurosci. 2008;28:4488-500 pubmed 出版商
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Lelouvier B, Tamagno G, Kaindl A, Roland A, Lelievre V, Le Verche V, et al. Dynamics of somatostatin type 2A receptor cargoes in living hippocampal neurons. J Neurosci. 2008;28:4336-49 pubmed 出版商
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Hida T, Ikeda H, Kametaka S, Akazawa C, Kohsaka S, Ebisu S, et al. Specific depletion of GGA2 causes cathepsin D missorting in HeLa cells. Arch Histol Cytol. 2007;70:303-12 pubmed
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Koch A, Scherr M, Breyer B, Mancini A, Kardinal C, Battmer K, et al. Inhibition of Abl tyrosine kinase enhances nerve growth factor-mediated signaling in Bcr-Abl transformed cells via the alteration of signaling complex and the receptor turnover. Oncogene. 2008;27:4678-89 pubmed 出版商
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Barth K, Weinhold K, Guenther A, Linge A, Gereke M, Kasper M. Characterization of the molecular interaction between caveolin-1 and the P2X receptors 4 and 7 in E10 mouse lung alveolar epithelial cells. Int J Biochem Cell Biol. 2008;40:2230-9 pubmed 出版商
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Parisiadou L, Bethani I, Michaki V, Krousti K, Rapti G, Efthimiopoulos S. Homer2 and Homer3 interact with amyloid precursor protein and inhibit Abeta production. Neurobiol Dis. 2008;30:353-64 pubmed 出版商
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Nishimura N, Sasaki T. Cell-surface biotinylation to study endocytosis and recycling of occludin. Methods Mol Biol. 2008;440:89-96 pubmed 出版商
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Jansen M, Pietiäinen V, Pölönen H, Rasilainen L, Koivusalo M, Ruotsalainen U, et al. Cholesterol substitution increases the structural heterogeneity of caveolae. J Biol Chem. 2008;283:14610-8 pubmed 出版商
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Murray J, Sarkar S, Wolkoff A. Single vesicle analysis of endocytic fission on microtubules in vitro. Traffic. 2008;9:833-847 pubmed 出版商
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Fujibayashi A, Taguchi T, Misaki R, Ohtani M, Dohmae N, Takio K, et al. Human RME-8 is involved in membrane trafficking through early endosomes. Cell Struct Funct. 2008;33:35-50 pubmed
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Craige B, Salazar G, Faundez V. Phosphatidylinositol-4-kinase type II alpha contains an AP-3-sorting motif and a kinase domain that are both required for endosome traffic. Mol Biol Cell. 2008;19:1415-26 pubmed 出版商
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Boudanova E, Navaroli D, Melikian H. Amphetamine-induced decreases in dopamine transporter surface expression are protein kinase C-independent. Neuropharmacology. 2008;54:605-12 pubmed 出版商
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Rauch S, Pulkkinen K, Saksela K, Fackler O. Human immunodeficiency virus type 1 Nef recruits the guanine exchange factor Vav1 via an unexpected interface into plasma membrane microdomains for association with p21-activated kinase 2 activity. J Virol. 2008;82:2918-29 pubmed
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van de Graaf S, Rescher U, Hoenderop J, Verkaart S, Bindels R, Gerke V. TRPV5 is internalized via clathrin-dependent endocytosis to enter a Ca2+-controlled recycling pathway. J Biol Chem. 2008;283:4077-86 pubmed
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Flanagan M, Oldenburg J, Reignier T, Holt N, Hamilton G, Martin V, et al. New world clade B arenaviruses can use transferrin receptor 1 (TfR1)-dependent and -independent entry pathways, and glycoproteins from human pathogenic strains are associated with the use of TfR1. J Virol. 2008;82:938-48 pubmed 出版商
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Reignier T, Oldenburg J, Flanagan M, Hamilton G, Martin V, Cannon P. Receptor use by the Whitewater Arroyo virus glycoprotein. Virology. 2008;371:439-46 pubmed
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Singh R, Wangemann P. Free radical stress-mediated loss of Kcnj10 protein expression in stria vascularis contributes to deafness in Pendred syndrome mouse model. Am J Physiol Renal Physiol. 2008;294:F139-48 pubmed
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Imai Y, Inoue H, Kataoka A, Hua Qin W, Masuda M, Ikeda T, et al. Pael receptor is involved in dopamine metabolism in the nigrostriatal system. Neurosci Res. 2007;59:413-25 pubmed
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Nini L, Waheed A, Panicker L, Czapiga M, Zhang J, Simonds W. R7-binding protein targets the G protein beta 5/R7-regulator of G protein signaling complex to lipid rafts in neuronal cells and brain. BMC Biochem. 2007;8:18 pubmed
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Oztan A, Silvis M, Weisz O, Bradbury N, Hsu S, Goldenring J, et al. Exocyst requirement for endocytic traffic directed toward the apical and basolateral poles of polarized MDCK cells. Mol Biol Cell. 2007;18:3978-92 pubmed
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Schwab W, Harada H, Goetz W, Nowicki M, Witt M, Kasper M, et al. Immunocytochemical and biochemical detection of EMMPRIN in the rat tooth germ: differentiation-dependent co-expression with MMPs and co-localization with caveolin-1 in membrane rafts of dental epithelial cells. Histochem Cell Biol. 2007;128:195-203 pubmed
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Li X, Serwanski D, Miralles C, Bahr B, De Blas A. Two pools of Triton X-100-insoluble GABA(A) receptors are present in the brain, one associated to lipid rafts and another one to the post-synaptic GABAergic complex. J Neurochem. 2007;102:1329-45 pubmed
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Grosse S, Aron Y, Thévenot G, Monsigny M, Fajac I. Cytoskeletal involvement in the cellular trafficking of plasmid/PEI derivative complexes. J Control Release. 2007;122:111-7 pubmed
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Storch C, Ehehalt R, Haefeli W, Weiss J. Localization of the human breast cancer resistance protein (BCRP/ABCG2) in lipid rafts/caveolae and modulation of its activity by cholesterol in vitro. J Pharmacol Exp Ther. 2007;323:257-64 pubmed
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Zhao Z, Li X, Hao J, Winston J, Weinman S. The ClC-3 chloride transport protein traffics through the plasma membrane via interaction of an N-terminal dileucine cluster with clathrin. J Biol Chem. 2007;282:29022-31 pubmed
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Ducharme N, Williams J, Oztan A, Apodaca G, Lapierre L, Goldenring J. Rab11-FIP2 regulates differentiable steps in transcytosis. Am J Physiol Cell Physiol. 2007;293:C1059-72 pubmed
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Ignoul S, Simaels J, Hermans D, Annaert W, Eggermont J. Human ClC-6 is a late endosomal glycoprotein that associates with detergent-resistant lipid domains. PLoS ONE. 2007;2:e474 pubmed
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Fu D, van Dam E, Brymora A, Duggin I, Robinson P, Roufogalis B. The small GTPases Rab5 and RalA regulate intracellular traffic of P-glycoprotein. Biochim Biophys Acta. 2007;1773:1062-72 pubmed
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Goenaga A, Zhou Y, Legay C, Bougherara H, Huang L, Liu B, et al. Identification and characterization of tumor antigens by using antibody phage display and intrabody strategies. Mol Immunol. 2007;44:3777-88 pubmed
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Gil C, Cubi R, Aguilera J. Shedding of the p75NTR neurotrophin receptor is modulated by lipid rafts. FEBS Lett. 2007;581:1851-8 pubmed
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Abache T, Le Naour F, Planchon S, Harper F, Boucheix C, Rubinstein E. The transferrin receptor and the tetraspanin web molecules CD9, CD81, and CD9P-1 are differentially sorted into exosomes after TPA treatment of K562 cells. J Cell Biochem. 2007;102:650-64 pubmed
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Balbis A, Parmar A, Wang Y, Baquiran G, Posner B. Compartmentalization of signaling-competent epidermal growth factor receptors in endosomes. Endocrinology. 2007;148:2944-54 pubmed
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Lakkaraju A, Luyet P, Parone P, Falguières T, Strub K. Inefficient targeting to the endoplasmic reticulum by the signal recognition particle elicits selective defects in post-ER membrane trafficking. Exp Cell Res. 2007;313:834-47 pubmed
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Reversi A, Rimoldi V, Brambillasca S, Chini B. Effects of cholesterol manipulation on the signaling of the human oxytocin receptor. Am J Physiol Regul Integr Comp Physiol. 2006;291:R861-9 pubmed
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Gaggioli C, Robert G, Bertolotto C, Bailet O, Abbe P, Spadafora A, et al. Tumor-derived fibronectin is involved in melanoma cell invasion and regulated by V600E B-Raf signaling pathway. J Invest Dermatol. 2007;127:400-10 pubmed
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Shackelford R, Fu Y, Manuszak R, Brooks T, Sequeira A, Wang S, et al. Iron chelators reduce chromosomal breaks in ataxia-telangiectasia cells. DNA Repair (Amst). 2006;5:1327-36 pubmed
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Rutherford A, Traer C, Wassmer T, Pattni K, Bujny M, Carlton J, et al. The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport. J Cell Sci. 2006;119:3944-57 pubmed
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Ng P, Helguera G, Daniels T, Lomas S, Rodriguez J, Schiller G, et al. Molecular events contributing to cell death in malignant human hematopoietic cells elicited by an IgG3-avidin fusion protein targeting the transferrin receptor. Blood. 2006;108:2745-54 pubmed
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Salazar G, Craige B, Styers M, Newell Litwa K, Doucette M, Wainer B, et al. BLOC-1 complex deficiency alters the targeting of adaptor protein complex-3 cargoes. Mol Biol Cell. 2006;17:4014-26 pubmed
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O Donnell K, Yu D, Zeller K, Kim J, Racke F, Thomas Tikhonenko A, et al. Activation of transferrin receptor 1 by c-Myc enhances cellular proliferation and tumorigenesis. Mol Cell Biol. 2006;26:2373-86 pubmed
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Monzo P, Mari M, Kaddai V, Gonzalez T, Le Marchand Brustel Y, Cormont M. CD2AP, Rabip4, and Rabip4': analysis of interaction with Rab4a and regulation of endosomes morphology. Methods Enzymol. 2005;403:107-18 pubmed
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Parisiadou L, Efthimiopoulos S. Expression of mDab1 promotes the stability and processing of amyloid precursor protein and this effect is counteracted by X11alpha. Neurobiol Aging. 2007;28:377-88 pubmed
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Chen Z, Nomura J, Suzuki T, Suzuki N. Enhanced expression of transferrin receptor confers UV-resistance in human and monkey cells. J Radiat Res. 2005;46:443-51 pubmed
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Barel M, Pizzato N, Le Bouteiller P, Wiertz E, Lenfant F. Subtle sequence variation among MHC class I locus products greatly influences sensitivity to HCMV US2- and US11-mediated degradation. Int Immunol. 2006;18:173-82 pubmed
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Lerdrup M, Hommelgaard A, Grandal M, van Deurs B. Geldanamycin stimulates internalization of ErbB2 in a proteasome-dependent way. J Cell Sci. 2006;119:85-95 pubmed
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Zeng X, Tamai K, Doble B, Li S, Huang H, Habas R, et al. A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation. Nature. 2005;438:873-7 pubmed
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Snyder C, Mardones G, Ladinsky M, Howell K. GMx33 associates with the trans-Golgi matrix in a dynamic manner and sorts within tubules exiting the Golgi. Mol Biol Cell. 2006;17:511-24 pubmed
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Strick D, Elferink L. Rab15 effector protein: a novel protein for receptor recycling from the endocytic recycling compartment. Mol Biol Cell. 2005;16:5699-709 pubmed
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Theos A, Tenza D, Martina J, Hurbain I, Peden A, Sviderskaya E, et al. Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes. Mol Biol Cell. 2005;16:5356-72 pubmed
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Engelking L, Liang G, Hammer R, Takaishi K, Kuriyama H, Evers B, et al. Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins. J Clin Invest. 2005;115:2489-98 pubmed
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Barel M, Hassink G, van Voorden S, Wiertz E. Human cytomegalovirus-encoded US2 and US11 target unassembled MHC class I heavy chains for degradation. Mol Immunol. 2006;43:1258-66 pubmed
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Park G, Best S, Bloom M. Two mink parvoviruses use different cellular receptors for entry into CRFK cells. Virology. 2005;340:1-9 pubmed
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Doyotte A, Russell M, Hopkins C, Woodman P. Depletion of TSG101 forms a mammalian "Class E" compartment: a multicisternal early endosome with multiple sorting defects. J Cell Sci. 2005;118:3003-17 pubmed
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Berryman S, Clark S, Monaghan P, Jackson T. Early events in integrin alphavbeta6-mediated cell entry of foot-and-mouth disease virus. J Virol. 2005;79:8519-34 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
转铁蛋白受体单克隆抗体(H68.4)
目录# :
13-6800
规格 :
100微克
价格 :
美国402
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
鸡, 仓鼠, 人类, 小鼠, 大鼠
应用 :
ELISA: Assay-dependent, Immunocytochemistry: 1:250, Immunohistochemistry (Paraffin): Assay-dependent, Immunomicroscopy: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 0.5 µg/mL
物种 :
鸡, 仓鼠, 人类, 小鼠, 大鼠
克隆 :
H68.4
抗体亚型 :
IgG1
储存 :
-20°C
描述 :
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
免疫原 :
重组人类转铁蛋白受体
格式 :
液体
应用w/稀释 :
ELISA: Assay-dependent, Immunocytochemistry: 1:250, Immunohistochemistry (Paraffin): Assay-dependent, Immunomicroscopy: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 0.5 µg/mL
别名 :
2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国