产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IL-6 Monoclonal Antibody (MP5-32C11), Biotin, eBioscience
目录 :
13-7062-81
规格 :
50微克
价格 :
美国121
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
生物素
克隆名称 :
MP5-32C11
反应物种 :
小鼠
应用 :
酶联免疫吸附测定
更多信息或购买 :
文章摘录数: 45
出版应用/物种/样本/稀释 | 参考文献 |
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Sakai M, Yamashita K, Takemoto N, Ohshima Y, Tsukimoto M, Shinkai Y, et al. Diesel exhaust (DE) aggravates pathology of delayed-type hypersensitivity (DTH) induced by methyl-bovine serum albumin (mBSA) in mice. J Toxicol Sci. 2009;34:483-92 pubmed
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Tsukimoto M, Nakatsukasa H, Sugawara K, Yamashita K, Kojima S. Repeated 0.5-Gy gamma irradiation attenuates experimental autoimmune encephalomyelitis with up-regulation of regulatory T cells and suppression of IL17 production. Radiat Res. 2008;170:429-36 pubmed
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Tago F, Tsukimoto M, Nakatsukasa H, Kojima S. Repeated 0.5-Gy gamma irradiation attenuates autoimmune disease in MRL-lpr/lpr mice with suppression of CD3+CD4-CD8-B220+ T-cell proliferation and with up-regulation of CD4+CD25+Foxp3+ regulatory T cells. Radiat Res. 2008;169:59-66 pubmed
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Minges Wols H, Ippolito J, Yu Z, Palmer J, White F, Le P, et al. The effects of microenvironment and internal programming on plasma cell survival. Int Immunol. 2007;19:837-46 pubmed
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Mutou Y, Ibuki Y, Kojima S. Immunomodulatory effects of ultraviolet B irradiation on atopic dermatitis in NC/Nga mice. Photodermatol Photoimmunol Photomed. 2007;23:135-44 pubmed
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Gouze M, Laffitte J, Pinton P, Dedieux G, Galinier A, Thouvenot J, et al. Effect of subacute oral doses of nivalenol on immune and metabolic defence systems in mice. Vet Res. 2007;38:635-46 pubmed
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Grigorian A, Lee S, Tian W, Chen I, Gao G, Mendelsohn R, et al. Control of T Cell-mediated autoimmunity by metabolite flux to N-glycan biosynthesis. J Biol Chem. 2007;282:20027-35 pubmed
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Le Barillec K, Magalhaes J, Corcuff E, Thuizat A, Sansonetti P, Phalipon A, et al. Roles for T and NK cells in the innate immune response to Shigella flexneri. J Immunol. 2005;175:1735-40 pubmed
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Finkelman F, Morris S. Development of an assay to measure in vivo cytokine production in the mouse. Int Immunol. 1999;11:1811-8 pubmed
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Sander B, Höidén I, Andersson U, Moller E, Abrams J. Similar frequencies and kinetics of cytokine producing cells in murine peripheral blood and spleen. Cytokine detection by immunoassay and intracellular immunostaining. J Immunol Methods. 1993;166:201-14 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
IL-6 Monoclonal Antibody (MP5-32C11), Biotin, eBioscience
目录# :
13-7062-81
规格 :
50微克
价格 :
美国121
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
ELISA:0.5-2微克/毫升
物种 :
小鼠
克隆 :
MP5-32C11
抗体亚型 :
IgG2a, kappa
储存 :
4° C, 不冻结
描述 :
Interleukin 6 (IL-6) is a multifunctional 26 kD protein originally discovered in the medium of RNA-stimulated fibroblastoid cells. IL-6 appears to be directly involved in the responses that occur after infection and cellular injury, and it may prove to be important as IL-1 and TNF-a in regulating the acute phase response. IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages and endothelial cells. IL-6 acts upon a variety of cells including myeloid progenitor cells, T cells, B cells, and hepatocytes. In addition, IL-6 appears to interact with IL-2 in the proliferation of T lymphocytes. IL-6 potentiates the proliferative effect of IL-3 on multipotential hematopoietic progenitors. IL-6 plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. IL-6 is a very useful culture supplement for the generation of a high number of antibody-producing hybridomas. Primarily produced at sites of acute and chronic inflammation, IL-6 is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of IL-6 is implicated in a wide variety of inflammation-associated disease states including diabetes mellitus and systemic juvenile rheumatoid arthritis.
格式 :
液体
应用w/稀释 :
ELISA:0.5-2微克/毫升
别名 :
B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6
更多信息或购买 :
公司信息
赛默飞世尔
产品浏览
- IL-6 Monoclonal Antibody (MP5-32C11), Biotin, eBioscience | 13-7062-85
- IL-6 Monoclonal Antibody (MQ2-39C3), Biotin, eBioscience | 13-7068-81
- IL-6 Monoclonal Antibody (MQ2-39C3), Biotin, eBioscience | 13-7068-85
- CCL2 (MCP-1) Monoclonal Antibody (2H5), Biotin, eBioscience | 13-7096-85
- IL-10 Monoclonal Antibody (JES5-2A5), Biotin, eBioscience | 13-7102-81
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