产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
CaMKII alpha Monoclonal Antibody (Cba-2)
目录 :
13-7300
规格 :
100微克
价格 :
美国482
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
Cba-2
反应物种 :
人类, 小鼠, 大鼠, 家羊
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 20
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:1000; 图 2a
Wilkinson B, Li J, Coba M. Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling. Sci Rep. 2017;7:5272 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 4b
Zagrebelsky M, Lonnemann N, Fricke S, Kellner Y, Preuß E, Michaelsen Preusse K, et al. Nogo-A regulates spatial learning as well as memory formation and modulates structural plasticity in the adult mouse hippocampus. Neurobiol Learn Mem. 2017;138:154-163 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:1000; 图 3
Cohen S, Li B, Tsien R, Ma H. Evolutionary and functional perspectives on signaling from neuronal surface to nucleus. Biochem Biophys Res Commun. 2015;460:88-99 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:200; 图 s4
Gu Q, Yu D, Hu Z, Liu X, Yang Y, Luo Y, et al. miR-26a and miR-384-5p are required for LTP maintenance and spine enlargement. Nat Commun. 2015;6:6789 pubmed 出版商
  • 免疫印迹; 大鼠
Domínguez Alonso A, Valdés Tovar M, Solís Chagoyán H, Benítez King G. Melatonin stimulates dendrite formation and complexity in the hilar zone of the rat hippocampus: participation of the Ca++/Calmodulin complex. Int J Mol Sci. 2015;16:1907-27 pubmed 出版商
  • 免疫细胞化学; 小鼠
  • 免疫印迹; 小鼠; 1:1000
  • 免疫细胞化学; 大鼠
Jia J, Hu Z, Nordman J, Li Z. The schizophrenia susceptibility gene dysbindin regulates dendritic spine dynamics. J Neurosci. 2014;34:13725-36 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Huang Y, Ruiz C, Eyler E, Lin K, Meffert M. Dual regulation of miRNA biogenesis generates target specificity in neurotrophin-induced protein synthesis. Cell. 2012;148:933-46 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2
Huang K, Huang F, Shetty P. Stimulation-mediated translocation of calmodulin and neurogranin from soma to dendrites of mouse hippocampal CA1 pyramidal neurons. Neuroscience. 2011;178:1-12 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Lapchak P, SCHUBERT D, Maher P. Delayed treatment with a novel neurotrophic compound reduces behavioral deficits in rabbit ischemic stroke. J Neurochem. 2011;116:122-31 pubmed 出版商
Desch K, Langer J, Schuman E. Dynamic bi-directional phosphorylation events associated with the reciprocal regulation of synapses during homeostatic up- and down-scaling. Cell Rep. 2021;36:109583 pubmed 出版商
Zhan Q, Jeon J, Li Y, Huang Y, Xiong J, Wang Q, et al. CAMK2/CaMKII activates MLKL in short-term starvation to facilitate autophagic flux. Autophagy. 2021;:1-19 pubmed 出版商
McKay S, Ryan T, McQueen J, Indersmitten T, Marwick K, Hasel P, et al. The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences. Cell Rep. 2018;25:841-851.e4 pubmed 出版商
Lee S, Shin S, Zhong P, Kim H, Kim D, Kim J, et al. Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes. Nat Commun. 2018;9:3434 pubmed 出版商
Cohen S, Suutari B, He X, Wang Y, Sanchez S, Tirko N, et al. Calmodulin shuttling mediates cytonuclear signaling to trigger experience-dependent transcription and memory. Nat Commun. 2018;9:2451 pubmed 出版商
Nobili A, Latagliata E, Viscomi M, Cavallucci V, Cutuli D, Giacovazzo G, et al. Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer's disease. Nat Commun. 2017;8:14727 pubmed 出版商
Nehra S, Bhardwaj V, Kar S, Saraswat D. Chronic Hypobaric Hypoxia Induces Right Ventricular Hypertrophy and Apoptosis in Rats: Therapeutic Potential of Nanocurcumin in Improving Adaptation. High Alt Med Biol. 2016;17:342-352 pubmed
Millon Fremillon A, Brunner M, Abed N, Collomb E, Ribba A, Block M, et al. Calcium and calmodulin-dependent serine/threonine protein kinase type II (CaMKII)-mediated intramolecular opening of integrin cytoplasmic domain-associated protein-1 (ICAP-1?) negatively regulates ?1 integrins. J Biol Chem. 2013;288:20248-60 pubmed 出版商
Tang F, Kalil K. Netrin-1 induces axon branching in developing cortical neurons by frequency-dependent calcium signaling pathways. J Neurosci. 2005;25:6702-15 pubmed
Fang L, Wu J, Lin Q, Willis W. Calcium-calmodulin-dependent protein kinase II contributes to spinal cord central sensitization. J Neurosci. 2002;22:4196-204 pubmed
Christopherson K, Hillier B, Lim W, Bredt D. PSD-95 assembles a ternary complex with the N-methyl-D-aspartic acid receptor and a bivalent neuronal NO synthase PDZ domain. J Biol Chem. 1999;274:27467-73 pubmed
产品信息
产品类型 :
抗体
产品名称 :
CaMKII alpha Monoclonal Antibody (Cba-2)
目录# :
13-7300
规格 :
100微克
价格 :
美国482
克隆性 :
单克隆
纯度 :
抗原亲和色谱
宿主 :
小鼠
反应物种 :
Fish, Human, Mouse, Ovine, Rat
应用 :
ELISA: 0.1-1 µg/mL, Immunohistochemistry (Paraffin): 1-5 µg/mL, Immunoprecipitation: 2 µg, Western Blot: 0.5-1 µg/mL
物种 :
Fish, Human, Mouse, Ovine, Rat
克隆 :
Cba-2
抗体亚型 :
IgG2a, kappa
储存 :
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
描述 :
The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+/calmodulin (CaM) binding and autophosphorylation and has been implicated in regulation of the cell cycle and transcription. It is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner.
免疫原 :
Purified rat brain CaM Kinase.
格式 :
液体
应用w/稀释 :
ELISA: 0.1-1 µg/mL, Immunohistochemistry (Paraffin): 1-5 µg/mL, Immunoprecipitation: 2 µg, Western Blot: 0.5-1 µg/mL
别名 :
alpha CaM kinase II; alpha-CaMKII; Ca2+/calmodulin-dependent protein kinase II; Ca2+/calmodulin-dependent protein kinase II alpha; Calci; calcium/calmodulin dependent protein kinase II alpha; calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha; calcium/calmodulin-dependent protein kinase II alpha; calcium/calmodulin-dependent protein kinase II alpha subunit; calcium/calmodulin-dependent protein kinase II alpha-B subunit; calcium/calmodulin-dependent protein kinase type II alpha chain; calcium/calmodulin-dependent protein kinase type II subunit alpha; CaM kinase II alpha subunit; caM kinase II subunit alpha; CaMK II; CAMK2; Camk2a; CAMKA; CaMKII; CaMK-II alpha subunit; caMK-II subunit alpha; CaMKIINalpha; CaM-kinase II alpha chain; EC 2.7.11.17; KIAA0968; mKIAA0968; OTTHUMP00000165787; OTTHUMP00000165788; Phospho-CaMKI; PK2CDD; PKCCD; R74975
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国