产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IFN gamma Monoclonal Antibody (R4-6A2), Biotin, eBioscience
目录 :
13-7312-85
规格 :
500微克
价格 :
美国309
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
生物素
克隆名称 :
R4-6A2
反应物种 :
小鼠
应用 :
酶联免疫吸附测定
更多信息或购买 :
文章摘录数: 118
出版应用/物种/样本/稀释参考文献
  • 酶联免疫吸附测定; 小鼠; 图 s7a
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Massilamany C, Steffen D, Reddy J. An epitope from Acanthamoeba castellanii that cross-react with proteolipid protein 139-151-reactive T cells induces autoimmune encephalomyelitis in SJL mice. J Neuroimmunol. 2010;219:17-24 pubmed 出版商
Sasajima N, Ogasawara T, Takemura N, Fujiwara R, Watanabe J, Sonoyama K. Role of intestinal Bifidobacterium pseudolongum in dietary fructo-oligosaccharide inhibition of 2,4-dinitrofluorobenzene-induced contact hypersensitivity in mice. Br J Nutr. 2010;103:539-48 pubmed 出版商
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Chaitra M, Shaila M, Nayak R. Characterization of T-cell immunogenicity of two PE/PPE proteins of Mycobacterium tuberculosis. J Med Microbiol. 2008;57:1079-86 pubmed 出版商
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Niikura M, Kamiya S, Kita K, Kobayashi F. Coinfection with nonlethal murine malaria parasites suppresses pathogenesis caused by Plasmodium berghei NK65. J Immunol. 2008;180:6877-84 pubmed
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Castilow E, Olson M, Meyerholz D, Varga S. Differential role of gamma interferon in inhibiting pulmonary eosinophilia and exacerbating systemic disease in fusion protein-immunized mice undergoing challenge infection with respiratory syncytial virus. J Virol. 2008;82:2196-207 pubmed
Couper K, Blount D, Hafalla J, Van Rooijen N, de Souza J, Riley E. Macrophage-mediated but gamma interferon-independent innate immune responses control the primary wave of Plasmodium yoelii parasitemia. Infect Immun. 2007;75:5806-18 pubmed
Park S, Han Y, Aleyas A, George J, Yoon H, Lee J, et al. Low-dose antigen-experienced CD4+ T cells display reduced clonal expansion but facilitate an effective memory pool in response to secondary exposure. Immunology. 2008;123:426-37 pubmed
Olson M, Varga S. CD8 T cells inhibit respiratory syncytial virus (RSV) vaccine-enhanced disease. J Immunol. 2007;179:5415-24 pubmed
Miyazaki S, Ishikawa F, Shimizu K, Ubagai T, Edelstein P, Yamaguchi K. Gr-1high polymorphonuclear leukocytes and NK cells act via IL-15 to clear intracellular Haemophilus influenzae in experimental murine peritonitis and pneumonia. J Immunol. 2007;179:5407-14 pubmed
Hamby K, Trexler A, Pearson T, Larsen C, Rigby M, Kean L. NK cells rapidly reject allogeneic bone marrow in the spleen through a perforin- and Ly49D-dependent, but NKG2D-independent mechanism. Am J Transplant. 2007;7:1884-96 pubmed
Denkinger C, Denkinger M, Forsthuber T. Pertussis toxin-induced cytokine differentiation and clonal expansion of T cells is mediated predominantly via costimulation. Cell Immunol. 2007;246:46-54 pubmed
Mutou Y, Ibuki Y, Kojima S. Immunomodulatory effects of ultraviolet B irradiation on atopic dermatitis in NC/Nga mice. Photodermatol Photoimmunol Photomed. 2007;23:135-44 pubmed
Gouze M, Laffitte J, Pinton P, Dedieux G, Galinier A, Thouvenot J, et al. Effect of subacute oral doses of nivalenol on immune and metabolic defence systems in mice. Vet Res. 2007;38:635-46 pubmed
Grigorian A, Lee S, Tian W, Chen I, Gao G, Mendelsohn R, et al. Control of T Cell-mediated autoimmunity by metabolite flux to N-glycan biosynthesis. J Biol Chem. 2007;282:20027-35 pubmed
Hofstetter H, Kovalovsky A, Shive C, Lehmann P, Forsthuber T. Neonatal induction of myelin-specific Th1/Th17 immunity does not result in experimental autoimmune encephalomyelitis and can protect against the disease in adulthood. J Neuroimmunol. 2007;187:20-30 pubmed
Lichtenegger F, Kuerten S, Faas S, Boehm B, Tary Lehmann M, Lehmann P. Dissociation of experimental allergic encephalomyelitis protective effect and allergic side reactions in tolerization with neuroantigen. J Immunol. 2007;178:4749-56 pubmed
Hermans I, Silk J, Gileadi U, Masri S, Shepherd D, Farrand K, et al. Dendritic cell function can be modulated through cooperative actions of TLR ligands and invariant NKT cells. J Immunol. 2007;178:2721-9 pubmed
Sakai T, Kogiso M, Mitsuya K, Komatsu T, Yamamoto S. Genistein enhances antigen-specific cytokine production in female DO11.10 transgenic mice. J Nutr Sci Vitaminol (Tokyo). 2006;52:327-32 pubmed
Vinay D, Kim J, Kwon B. Amelioration of mercury-induced autoimmunity by 4-1BB. J Immunol. 2006;177:5708-17 pubmed
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Tanaka T, Tago F, Fang S, Shimura N, Kojima S. Repeated 0.5-Gy gamma-ray irradiation attenuates autoimmune manifestations in MRL-lpr/lpr mice. Int J Radiat Biol. 2005;81:731-40 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
IFN gamma Monoclonal Antibody (R4-6A2), Biotin, eBioscience
目录# :
13-7312-85
规格 :
500微克
价格 :
美国309
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
ELISA:0.5-2微克/毫升
物种 :
小鼠
克隆 :
R4-6A2
抗体亚型 :
IgG1, kappa
储存 :
4° C, 不冻结
描述 :
IFN gamma (Interferon gamma, Type II interferon) is a macrophage activation factor, and immune interferon that is produced primarily by T-lymphocytes and natural killer cells in response to antigens, mitogens, Staphylococcus enterotoxin B, phytohemaglutanin and other cytokines. IFN gamma is a dimeric protein consisting of two 146 amino acid subunits. IFN gamma is a glycoprotein that exists, functionally, as a homodimer of approximately 45 kDa. On SDS-PAGE, IFN gamma appears as a combination of 25, 20 and minor 15.5 kDa bands as a result of differential glycosylation. The biological activity of the IFN gamma homodimer is highly species specific. Human IFN gamma does not show cross-reactivity with mouse. IFN gamma function includes the following: antiviral activity, tumor antiproliferative activity, induction of class I and II MHC, macrophage activation, and enhanced immunoglobulin secretion by B lymphocytes. IFN gamma is involved in cytokine regulation and also acts synergistically with other cytokines. Activation of IFN gamma takes place through binding of IFN gamma receptor I and II, and activating the JAK-STAT pathway. IFN gamma does not show any homology with IFN alpha or IFN beta but human IFN gamma shows about 40% sequence homology with mouse IFN gamma. IFN gamma is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. IFN gamma gene mutations are associated with aplastic anemia.
格式 :
液体
应用w/稀释 :
ELISA:0.5-2微克/毫升
别名 :
BoIFNG; cytokine; EGK_03901; gamma interferon; gamma interferon precursor; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; Ifng; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; interferon-gamma precursor; Interferon?; M-IFN-g; R-IFN-g
更多信息或购买 :
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国