产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
TNF alpha Antibody Cocktail, Biotin, eBioscience
目录 :
13-7326-85
规格 :
500微克
价格 :
美国368
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
生物素
克隆名称 :
MP6-XT3, MP6-XT22
反应物种 :
小鼠
应用 :
酶联免疫吸附测定
更多信息或购买 :
文章摘录数: 15
出版应用/物种/样本/稀释 | 参考文献 |
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Chackerian B, Lowy D, Schiller J. Conjugation of a self-antigen to papillomavirus-like particles allows for efficient induction of protective autoantibodies. J Clin Invest. 2001;108:415-23 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
TNF alpha Antibody Cocktail, Biotin, eBioscience
目录# :
13-7326-85
规格 :
500微克
价格 :
美国368
克隆性 :
Cocktail
纯度 :
亲和色谱
宿主 :
大鼠
反应物种 :
小鼠
应用 :
ELISA:0.5-2微克/毫升
物种 :
小鼠
克隆 :
MP6-XT3, MP6-XT22
抗体亚型 :
IgG1, kappa
储存 :
4° C, 不冻结
描述 :
TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions. Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice. Other functions of TNF-alpha include its role in the immune response to bacterial, viral, parasitic and certain fungal infections, as well as its role in the necrosis of specific tumors. TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon-gamma in its cytotoxicity. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.
格式 :
液体
应用w/稀释 :
ELISA:0.5-2微克/毫升
别名 :
APC1 protein; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; TNFA; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; TNFSF2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor alpha precursor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor necrosis factor-alpha precursor; tumor-necrosis factor; tumour necrosis factor
更多信息或购买 :
公司信息
赛默飞世尔
产品浏览
- GM-CSF Monoclonal Antibody (MP1-31G6), Biotin, eBioscience | 13-7332-81
- GM-CSF Monoclonal Antibody (MP1-31G6), Biotin, eBioscience | 13-7332-85
- TNF alpha Polyclonal Antibody, Biotin, eBioscience | 13-7341-81
- TNF alpha Polyclonal Antibody, Biotin, eBioscience | 13-7341-85
- TNF alpha Monoclonal Antibody (MAb11), Biotin, eBioscience | 13-7349-81
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