产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
α微管蛋白单克隆抗体(TU-01)
目录 :
13-8000
规格 :
100微克
价格 :
美国400.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
TU-01
反应物种 :
African green monkey, 人类, 小鼠, 大鼠, 非洲爪蛙
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 52
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:400
  • 免疫印迹; 小鼠; 1:400
Sasaki M, Yoshimura Miyakoshi M, Sato Y, Nakanuma Y. A possible involvement of endoplasmic reticulum stress in biliary epithelial autophagy and senescence in primary biliary cirrhosis. J Gastroenterol. 2015;50:984-95 pubmed 出版商
  • 免疫印迹; 人类
Hashimoto Y, Shirane M, Matsuzaki F, Saita S, Ohnishi T, Nakayama K. Protrudin regulates endoplasmic reticulum morphology and function associated with the pathogenesis of hereditary spastic paraplegia. J Biol Chem. 2014;289:12946-61 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Sasaki M, Miyakoshi M, Sato Y, Nakanuma Y. A possible involvement of p62/sequestosome-1 in the process of biliary epithelial autophagy and senescence in primary biliary cirrhosis. Liver Int. 2012;32:487-99 pubmed 出版商
  • 免疫印迹; 人类; 1:7500; 图 2, 3
Tong J, Furukawa Y, Sherwin A, Hornykiewicz O, Kish S. Heterogeneous intrastriatal pattern of proteins regulating axon growth in normal adult human brain. Neurobiol Dis. 2011;41:458-68 pubmed 出版商
  • 免疫沉淀; 人类; 图 5
  • 免疫细胞化学; 人类; 图 6
  • 免疫印迹; 人类; 图 4
Tai C, Shen S, Lee W, Liao C, Deng W, Chiou H, et al. Increased cellular apoptosis susceptibility (CSE1L/CAS) protein expression promotes protrusion extension and enhances migration of MCF-7 breast cancer cells. Exp Cell Res. 2010;316:2969-81 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Liao C, Luo S, Tsai C, Tsao T, Chen S, Jiang M. CAS Enhances Chemotherapeutic Drug-Induced p53 Accumulation and Apoptosis: Use of CAS for High-Sensitivity Anticancer Drug Screening. Toxicol Mech Methods. 2008;18:771-6 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Sasaki M, Yamaguchi J, Ikeda H, Itatsu K, Nakanuma Y. Polycomb group protein Bmi1 is overexpressed and essential in anchorage-independent colony formation, cell proliferation and repression of cellular senescence in cholangiocarcinoma: tissue and culture studies. Hum Pathol. 2009;40:1723-30 pubmed 出版商
  • 免疫细胞化学; 人类
Miyajima N, Maruyama S, Nonomura K, Hatakeyama S. TRIM36 interacts with the kinetochore protein CENP-H and delays cell cycle progression. Biochem Biophys Res Commun. 2009;381:383-7 pubmed 出版商
  • 免疫印迹; 人类
Tsao T, Tsai C, Tung J, Chen S, Yue C, Liao C, et al. Function of CSE1L/CAS in the secretion of HT-29 human colorectal cells and its expression in human colon. Mol Cell Biochem. 2009;327:163-70 pubmed 出版商
  • 免疫印迹; 人类; 1 ug/ml; 图 3
Kano S, Miyajima N, Fukuda S, Hatakeyama S. Tripartite motif protein 32 facilitates cell growth and migration via degradation of Abl-interactor 2. Cancer Res. 2008;68:5572-80 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Sasaki M, Ikeda H, Itatsu K, Yamaguchi J, Sawada S, Minato H, et al. The overexpression of polycomb group proteins Bmi1 and EZH2 is associated with the progression and aggressive biological behavior of hepatocellular carcinoma. Lab Invest. 2008;88:873-82 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 4
Abdulghani J, Gu L, Dagvadorj A, Lutz J, Leiby B, Bonuccelli G, et al. Stat3 promotes metastatic progression of prostate cancer. Am J Pathol. 2008;172:1717-28 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Omura T, Kaneko M, Onoguchi M, Koizumi S, Itami M, Ueyama M, et al. Novel functions of ubiquitin ligase HRD1 with transmembrane and proline-rich domains. J Pharmacol Sci. 2008;106:512-9 pubmed
  • 免疫组化; 小鼠; 图 1
Sumioka A, Saito Y, Sakuma M, Araki Y, Yamamoto T, Suzuki T. The X11L/X11beta/MINT2 and X11L2/X11gamma/MINT3 scaffold proteins shuttle between the nucleus and cytoplasm. Exp Cell Res. 2008;314:1155-62 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Kaneko M, Yasui S, Niinuma Y, Arai K, Omura T, Okuma Y, et al. A different pathway in the endoplasmic reticulum stress-induced expression of human HRD1 and SEL1 genes. FEBS Lett. 2007;581:5355-60 pubmed
  • 免疫印迹; 人类; 1:7500; 图 3
Tong J, Hornykiewicz O, Furukawa Y, Kish S. Marked dissociation between high noradrenaline versus low noradrenaline transporter levels in human nucleus accumbens. J Neurochem. 2007;102:1691-1702 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Li P, Waters R, Redfern S, Zhang M, Mao L, Annex B, et al. Oxidative phenotype protects myofibers from pathological insults induced by chronic heart failure in mice. Am J Pathol. 2007;170:599-608 pubmed
  • 免疫印迹; 小鼠
Nakaya T, Suzuki T. Role of APP phosphorylation in FE65-dependent gene transactivation mediated by AICD. Genes Cells. 2006;11:633-45 pubmed
  • 免疫印迹; 小鼠; 图 2
Akimoto T, Pohnert S, Li P, Zhang M, Gumbs C, Rosenberg P, et al. Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathway. J Biol Chem. 2005;280:19587-93 pubmed
  • 免疫印迹; 人类; 1:1000
Trushina E, Dyer R, Badger J, Ure D, Eide L, Tran D, et al. Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro. Mol Cell Biol. 2004;24:8195-209 pubmed
  • 免疫印迹; 小鼠
Tsunematsu R, Nakayama K, Oike Y, Nishiyama M, Ishida N, Hatakeyama S, et al. Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development. J Biol Chem. 2004;279:9417-23 pubmed
  • 免疫细胞化学; African green monkey; 图 4
Ruddy M, Wong G, Liu X, Yamamoto H, Kasayama S, Kirkwood K, et al. Functional cooperation between interleukin-17 and tumor necrosis factor-alpha is mediated by CCAAT/enhancer-binding protein family members. J Biol Chem. 2004;279:2559-67 pubmed
  • 免疫印迹; 小鼠; 1:1000; 图 6
Laurent V, Jaubert Miazza L, Desjardins R, Day R, Lindberg I. Biosynthesis of proopiomelanocortin-derived peptides in prohormone convertase 2 and 7B2 null mice. Endocrinology. 2004;145:519-28 pubmed
  • 免疫印迹; 小鼠; 图 7
Cheng S, Shao J, Charlton Kachigian N, Loewy A, Towler D. MSX2 promotes osteogenesis and suppresses adipogenic differentiation of multipotent mesenchymal progenitors. J Biol Chem. 2003;278:45969-77 pubmed
  • 免疫印迹; 人类; 图 2b
Kudo Y, Kitajjma S, Sato S, Miyauchi M, Ogawa I, Takata T. Establishment of an oral squamous cell carcinoma cell line with high invasive and p27 degradation activities from a lymph node metastasis. Oral Oncol. 2003;39:515-20 pubmed
  • 免疫沉淀; 非洲爪蛙; 图 2
Lessman C, Kim H. Soluble tubulin complexes in oocytes of the common leopard frog, Rana pipiens, contain gamma-tubulin. Mol Reprod Dev. 2001;60:128-36 pubmed
  • 免疫细胞化学; 大鼠; 图 2
Iijima K, Ando K, Takeda S, Satoh Y, Seki T, Itohara S, et al. Neuron-specific phosphorylation of Alzheimer's beta-amyloid precursor protein by cyclin-dependent kinase 5. J Neurochem. 2000;75:1085-91 pubmed
  • 免疫细胞化学; 大鼠; 图 2
Ando K, Oishi M, Takeda S, Iijima K, Isohara T, Nairn A, et al. Role of phosphorylation of Alzheimer's amyloid precursor protein during neuronal differentiation. J Neurosci. 1999;19:4421-7 pubmed
Ochoa Maganda V, Rangel Castañeda I, Suárez Rico D, Cortes Zarate R, Hernández Hernández J, Perez Rangel A, et al. Antigiardial Activity of Acetylsalicylic Acid Is Associated with Overexpression of HSP70 and Membrane Transporters. Pharmaceuticals (Basel). 2020;13: pubmed 出版商
Margiotta A, Frei D, Sendstad I, Janssen L, Neefjes J, Bakke O. Invariant chain regulates endosomal fusion and maturation through an interaction with the SNARE Vti1b. J Cell Sci. 2020;133: pubmed 出版商
Kito Y, Matsumoto M, Hatano A, Takami T, Oshikawa K, Matsumoto A, et al. Cell cycle-dependent localization of the proteasome to chromatin. Sci Rep. 2020;10:5801 pubmed 出版商
Torres M, McLaughlin K, Renegar R, Valsaraj S, Whitehurst K, Sharaf O, et al. Intracardiac administration of ephrinA1-Fc preserves mitochondrial bioenergetics during acute ischemia/reperfusion injury. Life Sci. 2019;239:117053 pubmed 出版商
Bellon A, Wegener A, Lescallette A, Valente M, Yang S, Gardette R, et al. Transdifferentiation of Human Circulating Monocytes Into Neuronal-Like Cells in 20 Days and Without Reprograming. Front Mol Neurosci. 2018;11:323 pubmed 出版商
Hashimoto Y, Shirane M, Nakayama K. TMEM55B contributes to lysosomal homeostasis and amino acid-induced mTORC1 activation. Genes Cells. 2018;23:418-434 pubmed 出版商
Lo P, Yao Y, Lee J, Zhang Y, Huang W, KANE M, et al. LIPG signaling promotes tumor initiation and metastasis of human basal-like triple-negative breast cancer. elife. 2018;7: pubmed 出版商
Velez D, Tsui B, Goshia T, Chute C, Han A, Carter H, et al. 3D collagen architecture induces a conserved migratory and transcriptional response linked to vasculogenic mimicry. Nat Commun. 2017;8:1651 pubmed 出版商
Kjos I, Borg Distefano M, Sætre F, Repnik U, Holland P, Jones A, et al. Rab7b modulates autophagic flux by interacting with Atg4B. EMBO Rep. 2017;18:1727-1739 pubmed 出版商
Skvarova Kramarzova K, Osborn M, Webber B, Defeo A, McElroy A, Kim C, et al. CRISPR/Cas9-Mediated Correction of the FANCD1 Gene in Primary Patient Cells. Int J Mol Sci. 2017;18: pubmed 出版商
Dhenge A, Limbkar K, Melinkeri S, Kale V, Limaye L. Arachidonic acid and Docosahexanoic acid enhance platelet formation from human apheresis-derived CD34+ cells. Cell Cycle. 2017;16:979-990 pubmed 出版商
Nunukova A, Neradil J, Skoda J, Jaroš J, Hampl A, Sterba J, et al. Atypical nuclear localization of CD133 plasma membrane glycoprotein in rhabdomyosarcoma cell lines. Int J Mol Med. 2015;36:65-72 pubmed 出版商
Benada J, Burdová K, Lidak T, von Morgen P, Macurek L. Polo-like kinase 1 inhibits DNA damage response during mitosis. Cell Cycle. 2015;14:219-31 pubmed 出版商
Morelli E, Ginefra P, Mastrodonato V, Beznoussenko G, Rusten T, Bilder D, et al. Multiple functions of the SNARE protein Snap29 in autophagy, endocytic, and exocytic trafficking during epithelial formation in Drosophila. Autophagy. 2014;10:2251-68 pubmed 出版商
Wallace N, Robinson K, Galloway D. Beta human papillomavirus E6 expression inhibits stabilization of p53 and increases tolerance of genomic instability. J Virol. 2014;88:6112-27 pubmed 出版商
Ren Y, Cheung H, von Maltzhan G, Agrawal A, Cowley G, Weir B, et al. Targeted tumor-penetrating siRNA nanocomplexes for credentialing the ovarian cancer oncogene ID4. Sci Transl Med. 2012;4:147ra112 pubmed 出版商
Lueck K, Hennig M, Lommatzsch A, Pauleikhoff D, Wasmuth S. Complement and UV-irradiated photoreceptor outer segments increase the cytokine secretion by retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 2012;53:1406-13 pubmed 出版商
Henderson P, Li T, He M, Zhang H, Malfatti M, Gandara D, et al. A microdosing approach for characterizing formation and repair of carboplatin-DNA monoadducts and chemoresistance. Int J Cancer. 2011;129:1425-34 pubmed 出版商
Nishiyama M, Oshikawa K, Tsukada Y, Nakagawa T, Iemura S, Natsume T, et al. CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis. Nat Cell Biol. 2009;11:172-82 pubmed 出版商
Hah S, Mundt J, Kim H, Sumbad R, Turteltaub K, Henderson P. Measurement of 7,8-dihydro-8-oxo-2'-deoxyguanosine metabolism in MCF-7 cells at low concentrations using accelerator mass spectrometry. Proc Natl Acad Sci U S A. 2007;104:11203-8 pubmed
Kaneko Oshikawa C, Nakagawa T, Yamada M, Yoshikawa H, Matsumoto M, Yada M, et al. Mammalian E4 is required for cardiac development and maintenance of the nervous system. Mol Cell Biol. 2005;25:10953-64 pubmed
Baghdoyan S, Lamartine J, Castel D, Pitaval A, Roupioz Y, Franco N, et al. Id2 reverses cell cycle arrest induced by {gamma}-irradiation in human HaCaT keratinocytes. J Biol Chem. 2005;280:15836-41 pubmed
Tian F, Byfield S, Parks W, Stuelten C, Nemani D, Zhang Y, et al. Smad-binding defective mutant of transforming growth factor beta type I receptor enhances tumorigenesis but suppresses metastasis of breast cancer cell lines. Cancer Res. 2004;64:4523-30 pubmed
Akimoto T, Ribar T, Williams R, Yan Z. Skeletal muscle adaptation in response to voluntary running in Ca2+/calmodulin-dependent protein kinase IV-deficient mice. Am J Physiol Cell Physiol. 2004;287:C1311-9 pubmed
产品信息
产品类型 :
抗体
产品名称 :
α微管蛋白单克隆抗体(TU-01)
目录# :
13-8000
规格 :
100微克
价格 :
美国400.00
克隆性 :
单克隆
纯度 :
Ammonium sulfate precipitation, Caprylic acid precipitation, sequential chromatography
宿主 :
小鼠
反应物种 :
人类, 小鼠
应用 :
ELISA: Assay-dependent, Immunocytochemistry: 1:250, Immunohistochemistry (Frozen): 1:10-1:100, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: 1:250
物种 :
人类, 小鼠
克隆 :
TU-01
抗体亚型 :
IgG1
储存 :
-20°C
描述 :
Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells.
免疫原 :
Reacts with peptides that correspond to aa 65-79 in the N-terminus of alpha-tubulin
格式 :
液体
应用w/稀释 :
ELISA: Assay-dependent, Immunocytochemistry: 1:250, Immunohistochemistry (Frozen): 1:10-1:100, Immunohistochemistry (Paraffin): 1:10-1:100, Western Blot: 1:250
别名 :
&agr-tubulin 84B; 1t; a1t; ALPHA 84C; alpha tubulin; alpha tubulin 84B; alpha[[1]] tubulin; alpha[[1]]-tubulin; alpha1; alpha1 tubulin; alpha1t; alpha1tub; alpha1tub84B; alpha1-tubulin; alpha84B; alphaT; alphat-1; alphatub; alpha-tub; alphaTub1; alphatub84; alphaTUB84B; alpha-tub84B; alphaTub84B-PA; alphatubulin; alpha-tubulin; Alpha-tubulin 1; Alpha-tubulin 2; Alpha-tubulin 3; Alpha-tubulin 3C; alpha-tubulin 3C/D; Alpha-tubulin 3D; Alpha-tubulin 3E; alpha-tubulin 4; Alpha-tubulin 6; alphaTubulin 84B; alpha-Tubulin 84B; alpha-Tubulin at 84B; alpha-tubulin I; Alpha-tubulin II; alpha-tubulin III; Alpha-tubulin isotype M-alpha-1; alpha-tubulin isotype M-alpha-2; Alpha-tubulin isotype M-alpha-4; alpha-tubulin isotype M-alpha-6; alpha-tubulin TUB1; alpha-tubulin ubiquitous; alphaTubulin84B; Alpha-Tubulin84B; ALS22; anon-EST:Liang-1.59; anon-EST:Liang-2.30; AT25469p; aTub84B; a-tub84B; bA408E5.3; B-ALPHA-1; bcm948; BEST:LD32507; cb944; CG1913; CG1913-PA; chr3R:2914276. 2914416; clone 1.59; clone 2.30; Detyrosinated tubulin alpha-1A chain; Detyrosinated tubulin alpha-1B chain; Detyrosinated tubulin alpha-1C chain; Detyrosinated tubulin alpha-3 chain; Detyrosinated tubulin alpha-3C chain; Detyrosinated tubulin alpha-3D chain; Detyrosinated tubulin alpha-3E chain; DM1alpha; Dmel CG1913; Dmel_CG1913; DTA1; fb22g06; FLJ30169; H2 ALPHA; H2-ALPHA; hum-a-tub1; hum-a-tub2; I79_019110; K-ALPHA-1; l(3)84Bd; l(3)g3; lis3; LOC100726777; LOC100731885; LOC100857858; LOC101118307; LOC106557476; M[a]4; M[a]6; ms(3)nc33; nc33; RGD1565476; similar to alpha-tubulin isoform 1; similar to tubulin alpha 1; T; Talpha1; Talpha1 alpha-tubulin; TBA1_DROME; Testis-specific alpha-tubulin; Tub; Tub 84B; TUB1; Tub1C; Tub84B; TUBA1; Tuba-1; tuba1 protein; TUBA1/3/4; Tuba1a; tuba1a.L; tuba1a-a; tuba1a-b; TUBA1B; TUBA1C; tuba1l; tuba1l2; TUBA2; TUBA3; TUBA3C; TUBA3D; TUBA3E; Tuba4; Tuba4a; TUBA5; Tuba6; tuba8.S; tubA84B; tubal2; Tubalpha1; tubulin; tubulin 1 alpha-chain; tubulin 1alpha; tubulin alpha; tubulin alpha 1a; tubulin alpha 1a L homeolog; tubulin alpha 1b; tubulin alpha 1c; tubulin alpha 3; tubulin alpha 3c; tubulin alpha 3e; tubulin alpha 4a; tubulin alpha 6; tubulin alpha 8 S homeolog; tubulin alpha1; tubulin alpha-1 chain; tubulin alpha1 promoter; Tubulin alpha-1A chain; tubulin alpha-1B chain; Tubulin alpha-1C chain; tubulin alpha-1C chain-like; tubulin alpha-2 chain; Tubulin alpha-3 chain; Tubulin alpha-3C chain; tubulin alpha-3C/D chain; Tubulin alpha-3D chain; Tubulin alpha-3E chain; tubulin alpha-4 chain; Tubulin alpha-4A chain; Tubulin alpha-5 chain; tubulin alpha-5 chain-like; tubulin alpha-6 chain; tubulin alpha-8 chain; tubulin alpha-ubiquitous chain; tubulin B-alpha-1; Tubulin H2-alpha; tubulin K-alpha-1; tubulin(alpha1); tubulin, alpha 1; tubulin, alpha 1 (testis specific); tubulin, alpha 1, like; tubulin, alpha 1, like 2; tubulin, alpha 1a; tubulin, alpha 1b; tubulin, alpha 1c; tubulin, alpha 2; tubulin, alpha 3c; tubulin, alpha 3e; tubulin, alpha 4; tubulin, alpha 4a; tubulin, alpha 5; tubulin, alpha 6; tubulin, alpha, brain-specific; tubulin, alpha, ubiquitous; tubulin1alpha; tubulin84B; Tubulin-alpha1; Unknown (protein for MGC:133894); unnamed protein product; wu:fb22g06; wu:fb37a10; XELAEV_18019849mg; XELAEV_18020901mg; YML085C
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国